scholarly article | Q13442814 |
P50 | author | Ross Vlahos | Q87918648 |
Stephen R. Robinson | Q37828979 | ||
P2093 | author name string | Jun Xu | |
Wen Tan | |||
Songpei Li | |||
Xiao-Yi Zeng | |||
Ji-Ming Ye | |||
Xiu Zhou | |||
Ali Mahzari | |||
P2860 | cites work | Liver-specific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice. | Q38311106 |
Increased levels of nuclear SREBP-1c associated with fatty livers in two mouse models of diabetes mellitus | Q38319698 | ||
Nonalcoholic fatty liver disease is associated with an almost twofold increased risk of incident type 2 diabetes and metabolic syndrome. Evidence from a systematic review and meta-analysis. | Q38669230 | ||
Repurposing Drugs to Target the Diabetes Epidemic | Q38743445 | ||
Non-alcoholic fatty liver disease (NAFLD) prevalence and its metabolic associations in patients with type 1 diabetes and type 2 diabetes | Q38833207 | ||
Screening for the efficacy on lipid accumulation in 3T3-L1 cells is an effective tool for the identification of new anti-diabetic compounds | Q39310551 | ||
Effect of matrine on the expression of substance P receptor and inflammatory cytokines production in human skin keratinocytes and fibroblasts | Q40139694 | ||
Role of unfolded protein response in lipogenesis | Q41128321 | ||
Heat treatment improves glucose tolerance and prevents skeletal muscle insulin resistance in rats fed a high-fat diet | Q43177148 | ||
Decreased expression of heat shock protein 72 in skeletal muscle of patients with type 2 diabetes correlates with insulin resistance | Q43935456 | ||
PPARalpha /gamma ragaglitazar eliminates fatty liver and enhances insulin action in fat-fed rats in the absence of hepatomegaly | Q44295528 | ||
Protective effects of matrine against progression of high-fructose diet-induced steatohepatitis by enhancing antioxidant and anti-inflammatory defences involving Nrf2 translocation | Q45345539 | ||
Restoration of autophagy alleviates hepatic ER stress and impaired insulin signalling transduction in high fructose-fed male mice | Q46961307 | ||
Effects of fructose and glucose overfeeding on hepatic insulin sensitivity and intrahepatic lipids in healthy humans. | Q51343064 | ||
Chronic inhibition of dipeptidyl peptidase-4 with a sitagliptin analog preserves pancreatic beta-cell mass and function in a rodent model of type 2 diabetes. | Q51497444 | ||
Fructose-induced in vivo insulin resistance and elevated plasma triglyceride levels in rats. | Q51620845 | ||
Obesity depresses the anti-inflammatory HSP70 pathway, contributing to NAFLD progression. | Q53013442 | ||
IRE1 impairs insulin signaling transduction of fructose-fed mice via JNK independent of excess lipid. | Q55069645 | ||
Investigation of the role of SREBP-1c in the pathogenesis of HCV-related steatosis | Q61895897 | ||
Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding | Q63372079 | ||
HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1alpha-XBP1 signaling through a physical interaction | Q21145793 | ||
Antidiabetic and antisteatotic effects of the selective fatty acid synthase (FAS) inhibitor platensimycin in mouse models of diabetes | Q24629052 | ||
Endoplasmic reticulum stress and the inflammatory basis of metabolic disease | Q24633352 | ||
Hepatitis C virus hijacks host lipid metabolism | Q24652319 | ||
Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis | Q28508851 | ||
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes | Q28575190 | ||
Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease | Q29619334 | ||
The Sweet Path to Metabolic Demise: Fructose and Lipid Synthesis | Q30249128 | ||
Mitochondrial dysfunction precedes insulin resistance and hepatic steatosis and contributes to the natural history of non-alcoholic fatty liver disease in an obese rodent model | Q34021867 | ||
Differing endoplasmic reticulum stress response to excess lipogenesis versus lipid oversupply in relation to hepatic steatosis and insulin resistance. | Q34166238 | ||
Oleanolic acid reduces hyperglycemia beyond treatment period with Akt/FoxO1-induced suppression of hepatic gluconeogenesis in type-2 diabetic mice. | Q34364516 | ||
Reversal of nonalcoholic hepatic steatosis, hepatic insulin resistance, and hyperglycemia by moderate weight reduction in patients with type 2 diabetes | Q34370610 | ||
Lipid-induced insulin resistance: unravelling the mechanism | Q34370958 | ||
Nonalcoholic steatosis and steatohepatitis. III. Peroxisomal beta-oxidation, PPAR alpha, and steatohepatitis | Q34436747 | ||
PPARδ agonists have opposing effects on insulin resistance in high fat-fed rats and mice due to different metabolic responses in muscle | Q35005682 | ||
Chronic hepatitis C is associated with peripheral rather than hepatic insulin resistance. | Q35016133 | ||
Radix Sophorae flavescentis for chronic hepatitis B: a systematic review of randomized trials | Q35207408 | ||
Effect of a High-Fructose Weight-Maintaining Diet on Lipogenesis and Liver Fat. | Q35680888 | ||
The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes | Q35811523 | ||
Identification of matrine as a promising novel drug for hepatic steatosis and glucose intolerance with HSP72 as an upstream target | Q36016417 | ||
HSP72 protects against obesity-induced insulin resistance | Q36446531 | ||
Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice | Q36479005 | ||
Activation of PPARα ameliorates hepatic insulin resistance and steatosis in high fructose-fed mice despite increased endoplasmic reticulum stress. | Q36867522 | ||
Hepatitis C virus infection activates an innate pathway involving IKK-α in lipogenesis and viral assembly | Q36913366 | ||
GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice | Q37170811 | ||
Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans | Q37170824 | ||
Physiologically based pharmacokinetics of matrine in the rat after oral administration of pure chemical and ACAPHA | Q37188046 | ||
Dissociating fatty liver and diabetes | Q38050214 | ||
De novo lipogenesis in health and disease. | Q38210722 | ||
P433 | issue | 11 | |
P304 | page(s) | 1753-1759 | |
P577 | publication date | 2018-07-06 | |
P1433 | published in | Acta Pharmacologica Sinica | Q15749885 |
P1476 | title | Repurposing matrine for the treatment of hepatosteatosis and associated disorders in glucose homeostasis in mice | |
P478 | volume | 39 |
Q61799706 | Effects of Radix Linderae extracts on a mouse model of diabetic bladder dysfunction in later decompensated phase |
Q64093846 | Matrine Protects Against MCD-Induced Development of NASH via Upregulating HSP72 and Downregulating mTOR in a Manner Distinctive From Metformin |
Q59330033 | Matrine attenuates endoplasmic reticulum stress and mitochondrion dysfunction in nonalcoholic fatty liver disease by regulating SERCA pathway |
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