| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Mark A. Herman | Q63365209 |
| P2093 | author name string | Varman T Samuel | |
| P2860 | cites work | Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade | Q77795070 |
| National estimates of dietary fructose intake increased from 1977 to 2004 in the United States | Q83747795 | ||
| Identification of human and rat FAD-AMP lyase (cyclic FMN forming) as ATP-dependent dihydroxyacetone kinases | Q24295027 | ||
| Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice | Q24306427 | ||
| FGF-21 as a novel metabolic regulator | Q24523933 | ||
| Genome-wide association analyses identify 18 new loci associated with serum urate concentrations | Q24620065 | ||
| Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans | Q24643492 | ||
| FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response | Q24653481 | ||
| Kinetic analysis of the liver-type (GLUT2) and brain-type (GLUT3) glucose transporters in Xenopus oocytes: substrate specificities and effects of transport inhibitors | Q27865317 | ||
| Beverage purchases from stores in Mexico under the excise tax on sugar sweetened beverages: observational study | Q28005561 | ||
| Peroxisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta ), a novel PGC-1-related transcription coactivator associated with host cell factor | Q28208668 | ||
| Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity | Q28253424 | ||
| Regulation of expression of the human fructose transporter (GLUT5) by cyclic AMP | Q28369320 | ||
| Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
| Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis | Q28508851 | ||
| A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism | Q28513195 | ||
| Inhibition of protein kinase Cepsilon prevents hepatic insulin resistance in nonalcoholic fatty liver disease | Q28571421 | ||
| Glucose induces FGF21 mRNA expression through ChREBP activation in rat hepatocytes | Q28571616 | ||
| Effects of a High Fructose Diet on Lipogenic Enzyme Activities in Some Organs of Rats Fed ad libitum | Q67326294 | ||
| Effects of nutrients and hormones on transcriptional and post-transcriptional regulation of fatty acid synthase in rat liver | Q68523170 | ||
| Purification and Properties of Rat Liver Fructokinase | Q72231038 | ||
| Glucokinase regulatory protein may interact with glucokinase in the hepatocyte nucleus | Q72989985 | ||
| Dietary fructose induces a wide range of genes with distinct shift in carbohydrate and lipid metabolism in fed and fasted rat liver | Q28575499 | ||
| Aldolase-B knockout in mice phenocopies hereditary fructose intolerance in humans | Q28588701 | ||
| Both isoforms of ketohexokinase are dispensable for normal growth and development | Q28589951 | ||
| Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states | Q29615208 | ||
| Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21 | Q29615209 | ||
| Metabolic control through the PGC-1 family of transcription coactivators | Q29616509 | ||
| Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake | Q30412686 | ||
| mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway | Q30425628 | ||
| ²H enrichment distribution of hepatic glycogen from ²H₂O reveals the contribution of dietary fructose to glycogen synthesis | Q30580162 | ||
| Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis | Q33734679 | ||
| Sugar-sweetened beverage consumption is associated with abdominal fat partitioning in healthy adults | Q33888223 | ||
| Hepatic glucose uptake and disposition during short-term high-fat vs. high-fructose feeding | Q33913097 | ||
| American Academy of Pediatrics: The use and misuse of fruit juice in pediatrics | Q33945059 | ||
| Metabolic fate of fructose ingested with and without glucose in a mixed meal. | Q33963267 | ||
| Sugar-sweetened beverages and prevalence of the metabolically abnormal phenotype in the Framingham Heart Study | Q34071040 | ||
| Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma | Q34224637 | ||
| Novel locus including FGF21 is associated with dietary macronutrient intake | Q34325630 | ||
| Uric acid stimulates fructokinase and accelerates fructose metabolism in the development of fatty liver | Q34462446 | ||
| A dose-response study of consuming high-fructose corn syrup-sweetened beverages on lipid/lipoprotein risk factors for cardiovascular disease in young adults | Q34473275 | ||
| Effects of decreasing sugar-sweetened beverage consumption on body weight in adolescents: a randomized, controlled pilot study | Q34498698 | ||
| Development of muscle insulin resistance after liver insulin resistance in high-fat-fed rats | Q34975588 | ||
| Fructose ingestion acutely stimulates circulating FGF21 levels in humans | Q35040490 | ||
| The role of peroxisome proliferator-activated receptor gamma coactivator-1 beta in the pathogenesis of fructose-induced insulin resistance. | Q35090215 | ||
| Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease | Q35239565 | ||
| Consumption of fructose and high fructose corn syrup increase postprandial triglycerides, LDL-cholesterol, and apolipoprotein-B in young men and women | Q35432878 | ||
| Effect of a High-Fructose Weight-Maintaining Diet on Lipogenesis and Liver Fat. | Q35680888 | ||
| Dissociation of inositol-requiring enzyme (IRE1α)-mediated c-Jun N-terminal kinase activation from hepatic insulin resistance in conditional X-box-binding protein-1 (XBP1) knock-out mice | Q35709954 | ||
| Hepatic insulin signaling is required for obesity-dependent expression of SREBP-1c mRNA but not for feeding-dependent expression | Q36060375 | ||
| Fructose-induced increases in expression of intestinal fructolytic and gluconeogenic genes are regulated by GLUT5 and KHK. | Q36114134 | ||
| Moderate amounts of fructose consumption impair insulin sensitivity in healthy young men: a randomized controlled trial | Q36477877 | ||
| Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis | Q36557194 | ||
| FGF21 Regulates Sweet and Alcohol Preference. | Q36567992 | ||
| FGF21 Mediates Endocrine Control of Simple Sugar Intake and Sweet Taste Preference by the Liver | Q36588765 | ||
| Inhibition of ADRP prevents diet-induced insulin resistance | Q36877282 | ||
| Increased fibroblast growth factor 21 in obesity and nonalcoholic fatty liver disease | Q36889026 | ||
| Selective versus total insulin resistance: a pathogenic paradox | Q37076798 | ||
| Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans | Q37170824 | ||
| PGC-1β and ChREBP partner to cooperatively regulate hepatic lipogenesis in a glucose concentration-dependent manner | Q37173344 | ||
| Endocrine and metabolic effects of consuming fructose- and glucose-sweetened beverages with meals in obese men and women: influence of insulin resistance on plasma triglyceride responses. | Q37198051 | ||
| Glucokinase and molecular aspects of liver glycogen metabolism | Q37225692 | ||
| Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome | Q37324307 | ||
| XBP1: the last two decades | Q37649065 | ||
| The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome | Q37724585 | ||
| Novel insights into ChREBP regulation and function. | Q38099905 | ||
| FGF21-based pharmacotherapy--potential utility for metabolic disorders | Q38202720 | ||
| The role of the carbohydrate response element-binding protein in male fructose-fed rats | Q38319892 | ||
| Snacks, sweetened beverages, added sugars, and schools | Q38364996 | ||
| PKC-theta knockout mice are protected from fat-induced insulin resistance | Q39989111 | ||
| Hormone-stimulated phosphorylation of liver phosphofructokinase in vivo | Q40231592 | ||
| Prevalence of Obesity Among Adults and Youth: United States, 2011-2014. | Q40246125 | ||
| High-fat and high-sucrose (western) diet induces steatohepatitis that is dependent on fructokinase | Q41856930 | ||
| Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2. | Q42033681 | ||
| Investigation on the mechanism by which fructose, hexitols and other compounds regulate the translocation of glucokinase in rat hepatocytes | Q42034649 | ||
| Mechanisms of fructose-induced hypertriglyceridaemia in the rat. Activation of hepatic pyruvate dehydrogenase through inhibition of pyruvate dehydrogenase kinase | Q42161658 | ||
| Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease. | Q42462295 | ||
| Tissue Specific Effects of Dietary Carbohydrates and Obesity on ChREBPα and ChREBPβ Expression | Q42484522 | ||
| Response to carbohydrate and fat refeeding in the expression of genes involved in nutrient partitioning and metabolism: striking effects on fibroblast growth factor-21 induction. | Q43259536 | ||
| Replacing dietary glucose with fructose increases ChREBP activity and SREBP-1 protein in rat liver nucleus | Q43267910 | ||
| Increased protein kinase C theta in skeletal muscle of diabetic patients | Q43586617 | ||
| Stimulating effects of low-dose fructose on insulin-stimulated hepatic glycogen synthesis in humans | Q43618908 | ||
| Amelioration of high fructose-induced metabolic derangements by activation of PPARalpha | Q43948724 | ||
| Fasting and postprandial overproduction of intestinally derived lipoproteins in an animal model of insulin resistance. Evidence that chronic fructose feeding in the hamster is accompanied by enhanced intestinal de novo lipogenesis and ApoB48-contain | Q44031791 | ||
| Stearoyl-CoA desaturase 1 gene expression is necessary for fructose-mediated induction of lipogenic gene expression by sterol regulatory element-binding protein-1c-dependent and -independent mechanisms | Q44832224 | ||
| Plasma D-glucose, D-fructose and insulin responses after oral administration of D-glucose, D-fructose and sucrose to normal rats | Q45091942 | ||
| Hyperlipidemic effects of dietary saturated fats mediated through PGC-1beta coactivation of SREBP. | Q45244060 | ||
| Fructose-induced increases in neonatal rat intestinal fructose transport involve the PI3-kinase/Akt signaling pathway | Q45251295 | ||
| Study of hereditary fructose intolerance by use of 31P magnetic resonance spectroscopy | Q46779898 | ||
| Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides | Q46809732 | ||
| Restoration of autophagy alleviates hepatic ER stress and impaired insulin signalling transduction in high fructose-fed male mice | Q46961307 | ||
| Fructose overconsumption causes dyslipidemia and ectopic lipid deposition in healthy subjects with and without a family history of type 2 diabetes | Q47915943 | ||
| ChREBP*Mlx is the principal mediator of glucose-induced gene expression in the liver | Q50336015 | ||
| Intestinal SR-BI is upregulated in insulin-resistant states and is associated with overproduction of intestinal apoB48-containing lipoproteins. | Q51373683 | ||
| Changes of liver metabolite concentrations in adults with disorders of fructose metabolism after intravenous fructose by 31P magnetic resonance spectroscopy. | Q51593640 | ||
| Diet-induced epigenetic regulation in vivo of the intestinal fructose transporter Glut5 during development of rat small intestine. | Q51891571 | ||
| Induction by fructose force-feeding of histone H3 and H4 acetylation at their lysine residues around the Slc2a5 gene and its expression in mice. | Q54647472 | ||
| Acute Fructose Administration Decreases the Glycemic Response to an Oral Glucose Tolerance Test in Normal Adults1 | Q56610849 | ||
| P433 | issue | 10 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 719-730 | |
| P577 | publication date | 2016-07-04 | |
| P1433 | published in | Trends in Endocrinology and Metabolism | Q15265727 |
| P1476 | title | The Sweet Path to Metabolic Demise: Fructose and Lipid Synthesis | |
| P478 | volume | 27 |
| Q64096895 | A Pathophysiological Model of Non-Alcoholic Fatty Liver Disease Using Precision-Cut Liver Slices |
| Q57039736 | A Study on Neonatal Intake of Oleanolic Acid and Metformin in Rats () with Metabolic Dysfunction: Implications on Lipid Metabolism and Glucose Transport |
| Q37571422 | A critical role for ChREBP-mediated FGF21 secretion in hepatic fructose metabolism. |
| Q64946819 | A study on hepatopathic, dyslipidemic and immunogenic properties of fructosylated-HSA-AGE and binding of autoantibodies in sera of obese and overweight patients with fructosylated-HSA-AGE. |
| Q89861347 | Beneficial Effects of Lactobacillus plantarum Strains on Non-Alcoholic Fatty Liver Disease in High Fat/High Fructose Diet-Fed Rats |
| Q89880944 | Beverage Consumption and Longitudinal Changes in Lipoprotein Concentrations and Incident Dyslipidemia in US Adults: The Framingham Heart Study |
| Q54259624 | ChREBP Rather Than SHP Regulates Hepatic VLDL Secretion. |
| Q50936974 | ChREBP refines the hepatic response to fructose to protect the liver from injury. |
| Q60923925 | Childhood Fructoholism and Fructoholic Liver Disease |
| Q64057845 | Complementary foods in baby food pouches: position statement from the Nutrition Commission of the German Society for Pediatrics and Adolescent Medicine (DGKJ, e.V.) |
| Q99630796 | Dietary Additives and Supplements Revisited: The Fewer, the Safer for Liver and Gut Health |
| Q92826678 | Dietary Fructose and the Metabolic Syndrome |
| Q90665321 | Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate |
| Q97905921 | Dihydroxyacetone phosphate signals glucose availability to mTORC1 |
| Q47309989 | Effect of dietary palmitic and stearic acids on sucrose motivation and hypothalamic and striatal cell signals in the rat. |
| Q52649427 | Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf2 (NF-E2 p45-Related Factor 2). |
| Q42368231 | Fructose Consumption, Lipogenesis, and Non-Alcoholic Fatty Liver Disease. |
| Q50147806 | Fructose and sugar: A major mediator of non-alcoholic fatty liver disease. |
| Q49498180 | Fructose metabolism and metabolic disease |
| Q39168770 | Fructose and NAFLD: The Multifaceted Aspects of Fructose Metabolism |
| Q44406447 | High fructose-mediated attenuation of insulin receptor signaling does not affect PDGF-induced proliferative signaling in vascular smooth muscle cells. |
| Q34541913 | High-fructose diet is as detrimental as high-fat diet in the induction of insulin resistance and diabetes mediated by hepatic/pancreatic endoplasmic reticulum (ER) stress. |
| Q61818543 | Homeostasis of Glucose and Lipid in Non-Alcoholic Fatty Liver Disease |
| Q58700518 | Human hepatic 3D spheroids as a model for steatosis and insulin resistance |
| Q47553435 | Interplay between ChREBP and SREBP-1c Coordinates Postprandial Glycolysis and Lipogenesis in Livers of Mice |
| Q33868369 | Is the calorie concept a real solution to the obesity epidemic? |
| Q49396335 | Kiwifruit Non-Sugar Components Reduce Glycaemic Response to Co-Ingested Cereal in Humans |
| Q90685522 | Mechanisms of Insulin Action and Insulin Resistance |
| Q57109055 | Mechanistic and therapeutic advances in non-alcoholic fatty liver disease by targeting the gut microbiota |
| Q38845655 | Medical nutrition therapy for post-bariatric hypoglycemia: practical insights |
| Q90031078 | Metabolic Targets in Nonalcoholic Fatty Liver Disease |
| Q47779219 | Nonalcoholic Fatty Liver Disease as a Nexus of Metabolic and Hepatic Diseases |
| Q64076256 | Nutritional Regulation of Gene Expression: Carbohydrate-, Fat- and Amino Acid-Dependent Modulation of Transcriptional Activity |
| Q89450069 | Repurposing matrine for the treatment of hepatosteatosis and associated disorders in glucose homeostasis in mice |
| Q45988896 | The FGF21 response to fructose predicts metabolic health and persists after bariatric surgery in obese humans. |
| Q39152848 | The Role of Carbohydrate Response Element Binding Protein in Intestinal and Hepatic Fructose Metabolism |
| Q91698411 | The integrative biology of type 2 diabetes |
| Q59336549 | The protective effect of neonatal oral administration of oleanolic acid against the subsequent development of fructose-induced metabolic dysfunction in male and female rats |
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