| scholarly article | Q13442814 |
| P50 | author | Danielle E Haslam | Q56384257 |
| Sarah Anissa Hannou | Q57319834 | ||
| Mark A. Herman | Q63365209 | ||
| Nicola M. McKeown | Q95292624 | ||
| P2860 | cites work | Polyol pathway in human epididymis and semen | Q24294400 |
| Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice | Q24306427 | ||
| Molecular basis of essential fructosuria: molecular cloning and mutational analysis of human ketohexokinase (fructokinase) | Q24310921 | ||
| Properties of normal and mutant recombinant human ketohexokinases and implications for the pathogenesis of essential fructosuria | Q24318466 | ||
| Dietary and developmental regulation of intestinal sugar transport | Q24533525 | ||
| Absorption capacity of fructose in healthy adults. Comparison with sucrose and its constituent monosaccharides | Q24548149 | ||
| Obesity Is a Fibroblast Growth Factor 21 (FGF21)-Resistant State | Q24625976 | ||
| Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans | Q24643492 | ||
| Slc2a5 (Glut5) is essential for the absorption of fructose in the intestine and generation of fructose-induced hypertension | Q24652515 | ||
| Fructose-induced leptin resistance exacerbates weight gain in response to subsequent high-fat feeding | Q24656064 | ||
| Consumption of sugar sweetened beverages, artificially sweetened beverages, and fruit juice and incidence of type 2 diabetes: systematic review, meta-analysis, and estimation of population attributable fraction | Q26801197 | ||
| Separate circuitries encode the hedonic and nutritional values of sugar | Q27311559 | ||
| Sugar-sweetened beverage consumption and incident hypertension: a systematic review and meta-analysis of prospective cohorts | Q27694730 | ||
| Sugar consumption, metabolic disease and obesity: The state of the controversy | Q27968233 | ||
| Sequence, tissue distribution, and functional characterization of the rat fructose transporter GLUT5 | Q28116197 | ||
| Peroxisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta ), a novel PGC-1-related transcription coactivator associated with host cell factor | Q28208668 | ||
| Adverse metabolic effects of dietary fructose: results from the recent epidemiological, clinical, and mechanistic studies | Q28289130 | ||
| The effect of high glucose and oxidative stress on lens metabolism, aldose reductase, and senile cataractogenesis | Q28289860 | ||
| Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
| Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis | Q28508851 | ||
| Transport, metabolism, and endosomal trafficking-dependent regulation of intestinal fructose absorption | Q28509620 | ||
| Fructose-induced hypertension: essential role of chloride and fructose absorbing transporters PAT1 and Glut5 | Q28510658 | ||
| A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism | Q28513195 | ||
| Transcriptional activation of apolipoprotein CIII expression by glucose may contribute to diabetic dyslipidemia | Q28565000 | ||
| Glucose induces FGF21 mRNA expression through ChREBP activation in rat hepatocytes | Q28571616 | ||
| FGF21 is an endocrine signal of protein restriction | Q28572009 | ||
| Increased fibroblast growth factor 21 in obesity and nonalcoholic fatty liver disease | Q36889026 | ||
| Dietary sugars stimulate fatty acid synthesis in adults | Q36898127 | ||
| Facilitated hexose transporters: new perspectives on form and function | Q36910739 | ||
| New insights into ER stress-induced insulin resistance. | Q38024445 | ||
| Does fructose consumption contribute to non-alcoholic fatty liver disease? | Q38026247 | ||
| Hepatic expression and cellular distribution of the glucose transporter family. | Q38067388 | ||
| Novel insights into ChREBP regulation and function. | Q38099905 | ||
| The role of the carbohydrate response element-binding protein in male fructose-fed rats | Q38319892 | ||
| Impaired cellular insulin binding and insulin sensitivity induced by high-fructose feeding in normal subjects | Q38357079 | ||
| Integration of ChREBP-Mediated Glucose Sensing into Whole Body Metabolism. | Q38622648 | ||
| Adverse effects of fructose on cardiometabolic risk factors and hepatic lipid metabolism in subjects with abdominal obesity. | Q38761767 | ||
| Sugar-sweetened Beverage Consumption Among U.S. Youth, 2011-2014. | Q38992061 | ||
| Stimulation of human purine synthesis de novo by fructose infusion | Q39933905 | ||
| Comparative effects of fructose and glucose on the lipid and carbohydrate metabolism of perfused rat liver | Q40000632 | ||
| Eucalyptus leaf extract suppresses the postprandial elevation of portal, cardiac and peripheral fructose concentrations after sucrose ingestion in rats. | Q40625064 | ||
| No differential effect of beverages sweetened with fructose, high-fructose corn syrup, or glucose on systemic or adipose tissue inflammation in normal-weight to obese adults: a randomized controlled trial | Q40675350 | ||
| Regulation of hepatic de novo lipogenesis in humans | Q41138438 | ||
| Lipogenic transcription factor ChREBP mediates fructose-induced metabolic adaptations to prevent hepatotoxicity. | Q41661616 | ||
| Circulating fibroblast growth factor-21 is elevated in impaired glucose tolerance and type 2 diabetes and correlates with muscle and hepatic insulin resistance. | Q41760918 | ||
| The mechanism of adenosine triphosphate depletion in the liver after a load of fructose. A kinetic study of liver adenylate deaminase | Q41864594 | ||
| Investigation on the mechanism by which fructose, hexitols and other compounds regulate the translocation of glucokinase in rat hepatocytes | Q42034649 | ||
| The problem of establishing relationships between hepatic steatosis and hepatic insulin resistance | Q42113466 | ||
| Fructose 2,6-bisphosphate 2 years after its discovery | Q42124382 | ||
| Activation of aldose reductase from human tissues | Q42226117 | ||
| Fructose Consumption, Lipogenesis, and Non-Alcoholic Fatty Liver Disease. | Q42368231 | ||
| Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease. | Q42462295 | ||
| Reduced Circulating Insulin Enhances Insulin Sensitivity in Old Mice and Extends Lifespan | Q42512280 | ||
| Adverse effects of the classic antioxidant uric acid in adipocytes: NADPH oxidase-mediated oxidative/nitrosative stress | Q42829265 | ||
| Effect of administration of the fructose on the glycogenolytic action of glucagon. An investigation of the pathogeny of hereditary fructose intolerance. | Q42923926 | ||
| The immediate effects of insulin and fructose on the metabolism of the perfused liver. Changes in lipoprotein secretion, fatty acid oxidation and esterification, lipogenesis and carbohydrate metabolism | Q42924597 | ||
| Effects of short-term overfeeding with fructose, fat and fructose plus fat on plasma and hepatic lipids in healthy men. | Q43059708 | ||
| Overweight and seminal quality: a study of 794 patients | Q43200162 | ||
| Relationship between hyperuricemia (HUC) and metabolic syndrome (MS) in institutionalized elderly men. | Q43224141 | ||
| Response to carbohydrate and fat refeeding in the expression of genes involved in nutrient partitioning and metabolism: striking effects on fibroblast growth factor-21 induction. | Q43259536 | ||
| Replacing dietary glucose with fructose increases ChREBP activity and SREBP-1 protein in rat liver nucleus | Q43267910 | ||
| Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes | Q43833528 | ||
| Opiate-like effects of sugar on gene expression in reward areas of the rat brain | Q44890065 | ||
| Fructose-responsive genes in the small intestine of neonatal rats | Q44901291 | ||
| Hyperlipidemic effects of dietary saturated fats mediated through PGC-1beta coactivation of SREBP. | Q45244060 | ||
| On the conversion of fructose to glucose by guinea pig intestine | Q46306220 | ||
| Trends in sugar-sweetened beverage consumption among youth and adults in the United States: 1999-2010. | Q46624341 | ||
| Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides | Q46809732 | ||
| Increased hepatic de novo lipogenesis and mitochondrial efficiency in a model of obesity induced by diets rich in fructose | Q46942890 | ||
| Intestinal, but not hepatic, ChREBP is required for fructose tolerance. | Q47268980 | ||
| Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling | Q47708428 | ||
| Metabolism of fructose in the small intestine. 1. The effect of fructose feeding on fructose transport and metabolism in rat small intestine | Q48010332 | ||
| Decreased consumption of sugar-sweetened beverages improved selected biomarkers of chronic disease risk among US adults: 1999 to 2010. | Q51328641 | ||
| Soft drink consumption and risk of developing cardiometabolic risk factors and the metabolic syndrome in middle-aged adults in the community. | Q51467220 | ||
| The glucose-6-phosphatase/glucokinase ratio in the liver of obese-diabetic subjects. | Q51622379 | ||
| Metabolic effects of oral fructose in the liver of fasted rats. | Q51641155 | ||
| Role of the Kidney in the Metabolism of Fructose in 60-hour Fasted Humans | Q51650860 | ||
| Long-term effects of moderate fructose feeding on glucose tolerance parameters in rats. | Q51655865 | ||
| Effects of mannose and fructose on the synthesis and secretion of insulin | Q34501066 | ||
| Physiological handling of dietary fructose-containing sugars: implications for health | Q34519291 | ||
| Controversies about sugars: results from systematic reviews and meta-analyses on obesity, cardiometabolic disease and diabetes | Q34546202 | ||
| A protein from rat liver confers to glucokinase the property of being antagonistically regulated by fructose 6-phosphate and fructose 1-phosphate | Q34561586 | ||
| Review article: fructose malabsorption and the bigger picture | Q34600800 | ||
| A dual sugar challenge test for lipogenic sensitivity to dietary fructose | Q34617112 | ||
| The sorbitol pathway in the human lens: aldose reductase and polyol dehydrogenase. | Q34712879 | ||
| ChREBP mediates glucose repression of peroxisome proliferator-activated receptor alpha expression in pancreatic beta-cells | Q34787111 | ||
| Polyol pathway and diabetic peripheral neuropathy | Q34800429 | ||
| Fructose ingestion acutely stimulates circulating FGF21 levels in humans | Q35040490 | ||
| Glucose transporters (GLUT and SGLT): expanded families of sugar transport proteins. | Q35060202 | ||
| The role of peroxisome proliferator-activated receptor gamma coactivator-1 beta in the pathogenesis of fructose-induced insulin resistance. | Q35090215 | ||
| Is there a pathogenetic role for uric acid in hypertension and cardiovascular and renal disease? | Q35111714 | ||
| Association of fructose consumption and components of metabolic syndrome in human studies: a systematic review and meta-analysis. | Q35139058 | ||
| Effects of fructose on hepatic glucose metabolism | Q35154240 | ||
| Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease | Q35239565 | ||
| Differential effects of fructose versus glucose on brain and appetitive responses to food cues and decisions for food rewards | Q35644650 | ||
| Fructose levels are markedly elevated in cerebrospinal fluid compared to plasma in pregnant women | Q35649791 | ||
| The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans | Q36005304 | ||
| Endoplasmic reticulum stress in liver disease | Q36031838 | ||
| Hepatic insulin signaling is required for obesity-dependent expression of SREBP-1c mRNA but not for feeding-dependent expression | Q36060375 | ||
| First-Year Evaluation of Mexico's Tax on Nonessential Energy-Dense Foods: An Observational Study | Q36068218 | ||
| Fructose-induced increases in expression of intestinal fructolytic and gluconeogenic genes are regulated by GLUT5 and KHK. | Q36114134 | ||
| Fructose intake and risk of gout and hyperuricemia: a systematic review and meta-analysis of prospective cohort studies | Q36152073 | ||
| Effect of fructose consumption on insulin sensitivity in nondiabetic subjects: a systematic review and meta-analysis of diet-intervention trials. | Q36217404 | ||
| Uric acid induces hepatic steatosis by generation of mitochondrial oxidative stress: potential role in fructose-dependent and -independent fatty liver. | Q36418940 | ||
| Sugar-Sweetened Beverage Consumption Is Associated With Change of Visceral Adipose Tissue Over 6 Years of Follow-Up | Q36510530 | ||
| Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis | Q36557194 | ||
| FGF21 Regulates Sweet and Alcohol Preference. | Q36567992 | ||
| FGF21 Mediates Endocrine Control of Simple Sugar Intake and Sweet Taste Preference by the Liver | Q36588765 | ||
| HIF-driven SF3B1 induces KHK-C to enforce fructolysis and heart disease. | Q36666891 | ||
| Metabolic and endocrine profiles in response to systemic infusion of fructose and glucose in rhesus macaques | Q36692063 | ||
| Synergistic effect of uricase blockade plus physiological amounts of fructose-glucose on glomerular hypertension and oxidative stress in rats. | Q36699780 | ||
| Activation of PPARα ameliorates hepatic insulin resistance and steatosis in high fructose-fed mice despite increased endoplasmic reticulum stress. | Q36867522 | ||
| A splicing switch from ketohexokinase-C to ketohexokinase-A drives hepatocellular carcinoma formation | Q36955860 | ||
| Examining the addictive-like properties of binge eating using an animal model of sugar dependence | Q36966009 | ||
| The polyol pathway as a mechanism for diabetic retinopathy: attractive, elusive, and resilient | Q37068700 | ||
| Hyperuricemia, gout and the metabolic syndrome | Q37113366 | ||
| Sweetened beverage consumption and risk of coronary heart disease in women | Q37154702 | ||
| GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice | Q37170811 | ||
| Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans | Q37170824 | ||
| PGC-1β and ChREBP partner to cooperatively regulate hepatic lipogenesis in a glucose concentration-dependent manner | Q37173344 | ||
| Glucokinase and molecular aspects of liver glycogen metabolism | Q37225692 | ||
| Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome | Q37324307 | ||
| Diabetes regulates fructose absorption through thioredoxin-interacting protein | Q37329069 | ||
| ChREBP regulates fructose-induced glucose production independently of insulin signaling | Q37395843 | ||
| The role of diet in symptoms of irritable bowel syndrome in adults: a narrative review | Q37532807 | ||
| A critical role for ChREBP-mediated FGF21 secretion in hepatic fructose metabolism. | Q37571422 | ||
| The human brain produces fructose from glucose | Q37646879 | ||
| Insulin resistance and compensatory hyperinsulinemia: role in hypertension, dyslipidemia, and coronary heart disease | Q37678379 | ||
| The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome | Q37724585 | ||
| Elevated circulating lipasin/betatrophin in human type 2 diabetes and obesity | Q37738417 | ||
| Diabetes mellitus and sperm parameters. | Q37862912 | ||
| Uric acid and fructose: potential biological mechanisms. | Q37945960 | ||
| Implications of an animal model of sugar addiction, withdrawal and relapse for human health. | Q52289233 | ||
| The effectiveness of some sugars in stimulating licking behavior in the rat. | Q52321204 | ||
| Uric acid induces endothelial dysfunction by vascular insulin resistance associated with the impairment of nitric oxide synthesis. | Q53061295 | ||
| Insulin action and resistance in obesity and type 2 diabetes. | Q53733290 | ||
| Studies of the mechanism of fructose-induced hypertriglyceridemia in the rat. | Q54510482 | ||
| Impact of the Berkeley Excise Tax on Sugar-Sweetened Beverage Consumption | Q57311724 | ||
| Glucose 6-phosphate, rather than xylulose 5-phosphate, is required for the activation of ChREBP in response to glucose in the liver | Q61203329 | ||
| Determination of the kinetic constants of fructose transport and phosphorylation in the perfused rat liver | Q68686602 | ||
| Activity of hepatic glucose phosphorylating and NADPH generating enzymes in Zucker rats | Q69549256 | ||
| Decrease and Inhibition of Liver Glycogen Phosphorylase After Fructose: An Experimental Model for the Study of Hereditary Fructose Intolerance | Q69796055 | ||
| Conversion of fructose to glucose in the rabbit small intestine. A reappraisal of the direct pathway | Q70669792 | ||
| Metabolic intermediates in liver of rats given large amounts of fructose or dihydroxyacetone | Q72370685 | ||
| Essential fructosuria and hereditary fructose intolerance | Q72383358 | ||
| Glucokinase regulatory protein may interact with glucokinase in the hepatocyte nucleus | Q72989985 | ||
| Activation of liver pyruvate kinase by fructose-1-phosphate | Q77922444 | ||
| [Anomaly of hepatic aldolase in intolerance to fructose.] | Q79408429 | ||
| National estimates of dietary fructose intake increased from 1977 to 2004 in the United States | Q83747795 | ||
| Effects of fructose infusion on lactate and uric acid metabolism | Q93696336 | ||
| Structure and alternative splicing of the ketohexokinase gene | Q28580227 | ||
| Aldolase-B knockout in mice phenocopies hereditary fructose intolerance in humans | Q28588701 | ||
| Ketohexokinase: expression and localization of the principal fructose-metabolizing enzyme | Q28594314 | ||
| Hereditary fructose intolerance | Q28638020 | ||
| The Genotype-Tissue Expression (GTEx) project | Q28657968 | ||
| Banting lecture 1988. Role of insulin resistance in human disease | Q29547283 | ||
| Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states | Q29615208 | ||
| Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21 | Q29615209 | ||
| Metabolic control through the PGC-1 family of transcription coactivators | Q29616509 | ||
| Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease | Q29619334 | ||
| Added Sugars and Cardiovascular Disease Risk in Children: A Scientific Statement From the American Heart Association. | Q30248346 | ||
| The Sweet Path to Metabolic Demise: Fructose and Lipid Synthesis | Q30249128 | ||
| Dietary sugars intake and cardiovascular health: a scientific statement from the American Heart Association. | Q30380074 | ||
| Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake | Q30412686 | ||
| mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway | Q30425628 | ||
| Measurement of glucose and fructose in clinical samples using gas chromatography/mass spectrometry | Q33615615 | ||
| Glucose transporter 8 (GLUT8) mediates fructose-induced de novo lipogenesis and macrosteatosis | Q33676162 | ||
| Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis | Q33734679 | ||
| Serum uric acid levels and multiple health outcomes: umbrella review of evidence from observational studies, randomised controlled trials, and Mendelian randomisation studies | Q33770852 | ||
| Effects of fructose vs glucose on regional cerebral blood flow in brain regions involved with appetite and reward pathways | Q33825301 | ||
| Elevated Serum Sorbitol and not Fructose in Type 2 Diabetic Patients | Q33887976 | ||
| Fructose and related food carbohydrates. Sources, intake, absorption, and clinical implications | Q33972303 | ||
| Association between Serum Uric Acid Level and Metabolic Syndrome and Its Sex Difference in a Chinese Community Elderly Population | Q34032758 | ||
| Fructose, high-fructose corn syrup, sucrose, and nonalcoholic fatty liver disease or indexes of liver health: a systematic review and meta-analysis. | Q34056163 | ||
| Sugar-sweetened beverages and prevalence of the metabolically abnormal phenotype in the Framingham Heart Study | Q34071040 | ||
| Sucrose-sweetened beverages increase fat storage in the liver, muscle, and visceral fat depot: a 6-mo randomized intervention study | Q34113313 | ||
| Identification of biochemical differences between different forms of male infertility by nuclear magnetic resonance (NMR) spectroscopy. | Q34145713 | ||
| Sweetened beverage consumption, incident coronary heart disease, and biomarkers of risk in men. | Q34260855 | ||
| Dietary fructose reduces circulating insulin and leptin, attenuates postprandial suppression of ghrelin, and increases triglycerides in women | Q34325034 | ||
| Novel locus including FGF21 is associated with dietary macronutrient intake | Q34325630 | ||
| Dietary fructose and gastrointestinal symptoms: a review | Q34352997 | ||
| Sugar-sweetened beverages and weight gain in children and adults: a systematic review and meta-analysis | Q34365714 | ||
| Endogenous fructose production and fructokinase activation mediate renal injury in diabetic nephropathy | Q34427632 | ||
| Uric acid stimulates fructokinase and accelerates fructose metabolism in the development of fatty liver | Q34462446 | ||
| A dose-response study of consuming high-fructose corn syrup-sweetened beverages on lipid/lipoprotein risk factors for cardiovascular disease in young adults | Q34473275 | ||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 545-555 | |
| P577 | publication date | 2018-02-01 | |
| P1433 | published in | Journal of Clinical Investigation | Q3186904 |
| P1476 | title | Fructose metabolism and metabolic disease | |
| P478 | volume | 128 |
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