Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling

scientific article published on 3 October 2017

Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1172/JCI94585
P932PMC publication ID5663363
P698PubMed publication ID28972537

P50authorC. Ronald KahnQ16106681
Christopher B NewgardQ87867408
P2093author name stringDavid E Cohen
Shiho Fujisaka
Olga Ilkayeva
Kevin Fitzgerald
Samir Softic
Tata Nageswara Rao
Brian T O'Neill
Carole Harbison
Guo-Xiao Wang
Jennifer Willoughby
Manoj K Gupta
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Long-Term Fructose Intake Increases Adipogenic Potential: Evidence of Direct Effects of Fructose on Adipocyte Precursor CellsQ36846250
Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humansQ37170824
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ChREBP regulates fructose-induced glucose production independently of insulin signalingQ37395843
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Central glucagon-like peptide 1 receptor-induced anorexia requires glucose metabolism-mediated suppression of AMPK and is impaired by central fructoseQ39206330
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High-fat and high-sucrose (western) diet induces steatohepatitis that is dependent on fructokinaseQ41856930
Lipodystrophy Due to Adipose Tissue-Specific Insulin Receptor Knockout Results in Progressive NAFLD.Q41889139
Adiponectin resistance and proinflammatory changes in the visceral adipose tissue induced by fructose consumption via ketohexokinase-dependent pathwayQ42199169
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Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1cQ43848640
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The effect of a low fructose and low glycemic index/load (FRAGILE) dietary intervention on indices of liver function, cardiometabolic risk factors, and body composition in children and adolescents with nonalcoholic fatty liver disease (NAFLD).Q44475268
A reduced-glycemic load diet in the treatment of adolescent obesity.Q44545449
Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistanceQ44760628
A lipidomic analysis of nonalcoholic fatty liver disease.Q44931121
Nonalcoholic fatty liver disease in humans is associated with increased plasma endotoxin and plasminogen activator inhibitor 1 concentrations and with fructose intakeQ46473255
Up-regulation of PPAR-gamma mRNA expression in the liver of obese patients: an additional reinforcing lipogenic mechanism to SREBP-1c inductionQ50162855
Increased de novo lipogenesis is a distinct characteristic of individuals with nonalcoholic fatty liver disease.Q51330295
Effects of carbohydrate sugars and artificial sweeteners on appetite and the secretion of gastrointestinal satiety peptides.Q51381196
Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis.Q53555710
Dissociation of Hepatic Steatosis and Insulin Resistance in Mice Overexpressing DGAT in the LiverQ57016669
Mechanisms for the acute effect of fructose on postprandial lipemiaQ80447618
Increased P85alpha is a potent negative regulator of skeletal muscle insulin signaling and induces in vivo insulin resistance associated with growth hormone excessQ81222711
P4510describes a project that usesImageJQ1659584
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)4059-4074
P577publication date2017-10-03
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleDivergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling
P478volume127

Reverse relations

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