| scholarly article | Q13442814 |
| review article | Q7318358 |
| P50 | author | C. Ronald Kahn | Q16106681 |
| P2093 | author name string | David E Cohen | |
| Samir Softic | |||
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| Critical role of stearoyl-CoA desaturase-1 (SCD1) in the onset of diet-induced hepatic insulin resistance | Q42506602 | ||
| The role of ATP citrate-lyase in the metabolic regulation of plasma lipids. Hypolipidaemic effects of SB-204990, a lactone prodrug of the potent ATP citrate-lyase inhibitor SB-201076. | Q42991440 | ||
| Investigation of anthropometric, biochemical and dietary parameters of obese children with and without non-alcoholic fatty liver disease | Q43714030 | ||
| The global NAFLD epidemic | Q44238213 | ||
| High-fat, high-fructose diet induces hepatic iron overload via a hepcidin-independent mechanism prior to the onset of liver steatosis and insulin resistance in mice | Q44245342 | ||
| Suppression of diacylglycerol acyltransferase-2 (DGAT2), but not DGAT1, with antisense oligonucleotides reverses diet-induced hepatic steatosis and insulin resistance | Q28583146 | ||
| Hepatic de novo lipogenesis is present in liver-specific ACC1-deficient mice | Q28589371 | ||
| Critical nodes in signalling pathways: insights into insulin action | Q29614735 | ||
| Design and validation of a histological scoring system for nonalcoholic fatty liver disease | Q29614930 | ||
| Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease | Q29619334 | ||
| De novo lipogenesis in humans: metabolic and regulatory aspects | Q33655979 | ||
| ATP-citrate lyase deficiency in the mouse | Q33923761 | ||
| Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity | Q33960868 | ||
| High-fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis | Q34023013 | ||
| Consumption of added sugars and indicators of cardiovascular disease risk among US adolescents | Q34025295 | ||
| Sugar, uric acid, and the etiology of diabetes and obesity. | Q34038315 | ||
| Added sugar intake and cardiovascular diseases mortality among US adults | Q34039753 | ||
| Deficiency in hepatic ATP-citrate lyase affects VLDL-triglyceride mobilization and liver fatty acid composition in mice | Q34053069 | ||
| Increased fructose consumption is associated with fibrosis severity in patients with nonalcoholic fatty liver disease | Q34069352 | ||
| Dietary fructose reduction improves markers of cardiovascular disease risk in Hispanic-American adolescents with NAFLD. | Q34091776 | ||
| FATP2 is a hepatic fatty acid transporter and peroxisomal very long-chain acyl-CoA synthetase | Q34149531 | ||
| High dietary fructose intake: Sweet or bitter life? | Q34210101 | ||
| Sweetened beverage consumption, incident coronary heart disease, and biomarkers of risk in men. | Q34260855 | ||
| A randomized trial of sugar-sweetened beverages and adolescent body weight | Q34301068 | ||
| A trial of sugar-free or sugar-sweetened beverages and body weight in children | Q34301075 | ||
| Insulin concentration modulates hepatic lipid accumulation in mice in part via transcriptional regulation of fatty acid transport proteins | Q34321195 | ||
| A causal role for uric acid in fructose-induced metabolic syndrome | Q34460827 | ||
| Liver transplantation and non-alcoholic fatty liver disease | Q34499022 | ||
| Liver ATP synthesis is lower and relates to insulin sensitivity in patients with type 2 diabetes. | Q34507251 | ||
| Deletion of ELOVL6 blocks the synthesis of oleic acid but does not prevent the development of fatty liver or insulin resistance | Q34565290 | ||
| Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis | Q34609585 | ||
| Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin. | Q34657137 | ||
| Triglyceride accumulation protects against fatty acid-induced lipotoxicity | Q34866329 | ||
| PKCδ regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans | Q35015769 | ||
| Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasis | Q35039363 | ||
| Hepatic steatosis, inflammation, and ER stress in mice maintained long term on a very low-carbohydrate ketogenic diet. | Q35057010 | ||
| Presence and significance of microvesicular steatosis in nonalcoholic fatty liver disease | Q35115991 | ||
| Fatty acid synthesis is essential in embryonic development: fatty acid synthase null mutants and most of the heterozygotes die in utero | Q35142911 | ||
| Consumption of added sugars is decreasing in the United States | Q35163947 | ||
| Fast food diet mouse: novel small animal model of NASH with ballooning, progressive fibrosis, and high physiological fidelity to the human condition | Q35562084 | ||
| Dissociation of inositol-requiring enzyme (IRE1α)-mediated c-Jun N-terminal kinase activation from hepatic insulin resistance in conditional X-box-binding protein-1 (XBP1) knock-out mice | Q35709954 | ||
| Acetyl-CoA carboxylase 2-/- mutant mice are protected against fatty liver under high-fat, high-carbohydrate dietary and de novo lipogenic conditions. | Q35874567 | ||
| Diacylglycerol activation of protein kinase Cε and hepatic insulin resistance | Q35964800 | ||
| Hepatic insulin signaling is required for obesity-dependent expression of SREBP-1c mRNA but not for feeding-dependent expression | Q36060375 | ||
| Children with NAFLD are more sensitive to the adverse metabolic effects of fructose beverages than children without NAFLD. | Q36069817 | ||
| Higher dietary fructose is associated with impaired hepatic adenosine triphosphate homeostasis in obese individuals with type 2 diabetes | Q36120653 | ||
| Consumption of fructose- but not glucose-sweetened beverages for 10 weeks increases circulating concentrations of uric acid, retinol binding protein-4, and gamma-glutamyl transferase activity in overweight/obese humans | Q36295250 | ||
| The metabolic syndrome: a call to action | Q36351233 | ||
| Uric acid induces hepatic steatosis by generation of mitochondrial oxidative stress: potential role in fructose-dependent and -independent fatty liver. | Q36418940 | ||
| Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice | Q36479005 | ||
| Isocaloric fructose restriction and metabolic improvement in children with obesity and metabolic syndrome | Q36531438 | ||
| Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes | Q36698641 | ||
| Association between noninvasive fibrosis markers and mortality among adults with nonalcoholic fatty liver disease in the United States | Q36756206 | ||
| Mechanisms of hepatic triglyceride accumulation in non-alcoholic fatty liver disease | Q36788344 | ||
| Differential effects of central fructose and glucose on hypothalamic malonyl-CoA and food intake. | Q36964213 | ||
| An overview of the safety and efficacy of a novel, natural(-)-hydroxycitric acid extract (HCA-SX) for weight management. | Q37033923 | ||
| Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight loss | Q37105351 | ||
| Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans | Q37170824 | ||
| Fatty acid metabolism: target for metabolic syndrome. | Q37338828 | ||
| Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice | Q37375695 | ||
| The role of the lipogenic pathway in the development of hepatic steatosis. | Q37386081 | ||
| Interplay between FGF21 and insulin action in the liver regulates metabolism | Q37524205 | ||
| Lipoprotein metabolism, dyslipidemia, and nonalcoholic fatty liver disease | Q37705810 | ||
| The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome | Q37724585 | ||
| Hormonal and nutritional regulation of SCD1 gene expression. | Q37780318 | ||
| Risk of Cardiovascular Disease in Patients with Nonalcoholic Fatty Liver Disease | Q37794163 | ||
| Insulin signaling to hepatic lipid metabolism in health and disease. | Q37877710 | ||
| The role of fructose-enriched diets in mechanisms of nonalcoholic fatty liver disease | Q37963122 | ||
| Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss | Q38364224 | ||
| Decreased survival of subjects with elevated liver function tests during a 28-year follow-up. | Q38447369 | ||
| Silencing of hepatic fatty acid transporter protein 5 in vivo reverses diet-induced non-alcoholic fatty liver disease and improves hyperglycemia | Q39975300 | ||
| PKC-theta knockout mice are protected from fat-induced insulin resistance | Q39989111 | ||
| SITES OF INITIAL REMOVAL OF CHYLOMICRON TRIGLYCERIDE FATTY ACIDS FROM THE BLOOD. | Q40319790 | ||
| Increasing prevalence of the metabolic syndrome among u.s. Adults. | Q40479545 | ||
| Physiological and molecular mechanisms involved in nutritional regulation of fatty acid synthesis | Q40576744 | ||
| Diacylglycerol/protein kinase C signalling: a mechanism for insulin resistance? | Q40864322 | ||
| Regulation of hepatic de novo lipogenesis in humans | Q41138438 | ||
| High-fat and high-sucrose (western) diet induces steatohepatitis that is dependent on fructokinase | Q41856930 | ||
| CITRATE AND THE CONVERSION OF CARBOHYDRATE INTO FAT. THE ACTIVITIES OF CITRATE-CLEAVAGE ENZYME AND ACETATE THIOKINASE IN LIVERS OF STARVED AND RE-FED RATS | Q41997998 | ||
| Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2. | Q42033681 | ||
| P433 | issue | 5 | |
| P921 | main subject | liver disease | Q929737 |
| fatty liver disease | Q6058862 | ||
| P304 | page(s) | 1282-1293 | |
| P577 | publication date | 2016-02-08 | |
| P1433 | published in | Digestive Diseases and Sciences | Q15716711 |
| P1476 | title | Role of Dietary Fructose and Hepatic De Novo Lipogenesis in Fatty Liver Disease | |
| P478 | volume | 61 |
| Q64096895 | A Pathophysiological Model of Non-Alcoholic Fatty Liver Disease Using Precision-Cut Liver Slices |
| Q52324645 | A comparative genomics study of carbohydrate/glucose metabolic genes: from fish to mammals. |
| Q90436197 | Administration of ursolic acid to new-born pups prevents dietary fructose-induced non-alcoholic fatty liver disease in Sprague Dawley rats |
| Q38761767 | Adverse effects of fructose on cardiometabolic risk factors and hepatic lipid metabolism in subjects with abdominal obesity. |
| Q97523790 | Ameliorative Effects of Bredemolic Acid on Markers Associated with Renal Dysfunction in a Diet-Induced Prediabetic Rat Model |
| Q33749401 | An In Vivo Magnetic Resonance Spectroscopy Study of the Effects of Caloric and Non-Caloric Sweeteners on Liver Lipid Metabolism in Rats |
| Q90302599 | Association between dietary total antioxidant capacity and hepatocellular ballooning in nonalcoholic steatohepatitis: a cross-sectional study |
| Q89861347 | Beneficial Effects of Lactobacillus plantarum Strains on Non-Alcoholic Fatty Liver Disease in High Fat/High Fructose Diet-Fed Rats |
| Q89966279 | Bredemolic Acid Improves Cardiovascular Function and Attenuates Endothelial Dysfunction in Diet-Induced Prediabetes: Effects on Selected Markers |
| Q42015805 | Chronic consumption of fructose in combination with trans fatty acids but not with saturated fatty acids induces nonalcoholic steatohepatitis with fibrosis in rats |
| Q28072381 | Clinical assessment of hepatic de novo lipogenesis in non-alcoholic fatty liver disease |
| Q98291407 | Computational Modeling of Fructose Metabolism and Development in NAFLD |
| Q42502672 | Consumption of the total Western diet differentially affects the response to green tea in rodent models of chronic disease compared to the AIN93G diet. |
| Q97643687 | Conversion of a dietary fructose: new clues from the gut microbiome |
| Q93016060 | Cytochrome P450 endoplasmic reticulum-associated degradation (ERAD): therapeutic and pathophysiological implications |
| Q99630796 | Dietary Additives and Supplements Revisited: The Fewer, the Safer for Liver and Gut Health |
| Q92826678 | Dietary Fructose and the Metabolic Syndrome |
| Q64091151 | Dietary Sources of Fructose and Its Association with Fatty Liver in Mexican Young Adults |
| Q90438587 | Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins |
| Q90665321 | Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate |
| Q90665359 | Dietary modifications for enhanced cancer therapy |
| Q49612956 | Diets High in Fat or Fructose Differentially Modulate Bone Health and Lipid Metabolism |
| Q58110770 | Differential capability of metabolic substrates to promote hepatocellular lipid accumulation |
| Q47246053 | Disturbed Vitamin A Metabolism in Non-Alcoholic Fatty Liver Disease (NAFLD). |
| Q47708428 | Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling |
| Q53762139 | Ectopic fat: a target for cardiometabolic risk management. |
| Q55003303 | Effect of Dietary Sugar Intake on Biomarkers of Subclinical Inflammation: A Systematic Review and Meta-Analysis of Intervention Studies. |
| Q61806319 | Effect of Wakame and Carob Pod Snacks on Non-Alcoholic Fatty Liver Disease |
| Q93080906 | Effects of Fructose or Glucose on Circulating ApoCIII and Triglyceride and Cholesterol Content of Lipoprotein Subfractions in Humans |
| Q57245574 | Effects of Leaves Extract on High Glucose-Induced Metabolic Changes in HepG2 Cells |
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| Q60935528 | Gegen Qinlian Decoction Attenuates High-Fat Diet-Induced Steatohepatitis in Rats via Gut Microbiota |
| Q91715909 | Genetic Permissiveness and Dietary Glycemic Load Interact to Predict Type-II Diabetes in the Nile rat (Arvicanthis niloticus) |
| Q55515105 | Habitual Fructose Intake Relates to Insulin Sensitivity and Fatty Liver Index in Recent-Onset Type 2 Diabetes Patients and Individuals without Diabetes. |
| Q46237033 | Hepatoprotective effect of calculus bovis sativus on nonalcoholic fatty liver disease in mice by inhibiting oxidative stress and apoptosis of hepatocytes. |
| Q92455104 | High-Fat Feeding in Time-Dependent Manner Affects Metabolic Routes Leading to Nervonic Acid Synthesis in NAFLD |
| Q55374784 | Importance of Nutrients and Nutrient Metabolism on Human Health. |
| Q47709525 | Increased incidence of non-alcoholic fatty liver disease in male rat offspring exposed to fluoxetine during fetal and neonatal life involves the NLRP3 inflammasome and augmented de novo hepatic lipogenesis. |
| Q47744258 | Influence of dietary macronutrients on liver fat accumulation and metabolism. |
| Q92416873 | Interleukin-12p35 deficiency enhances mitochondrial dysfunction and aggravates cardiac remodeling in aging mice |
| Q47553435 | Interplay between ChREBP and SREBP-1c Coordinates Postprandial Glycolysis and Lipogenesis in Livers of Mice |
| Q88643832 | Intestinal Absorption of Fructose |
| Q92441889 | Intestinal Fructose and Glucose Metabolism in Health and Disease |
| Q92354069 | Isocaloric Fructose Restriction Reduces Serum d-Lactate Concentration in Children With Obesity and Metabolic Syndrome |
| Q101051109 | Ketohexokinase-A acts as a nuclear protein kinase that mediates fructose-induced metastasis in breast cancer |
| Q64326583 | Leucrose, a Sucrose Isomer, Suppresses Hepatic Fat Accumulation by Regulating Hepatic Lipogenesis and Fat Oxidation in High-fat Diet-induced Obese Mice |
| Q45875766 | Lipocalin-2 in Fructose-Induced Fatty Liver Disease |
| Q39227666 | Liver Fatty Acid Composition and Inflammation in Mice Fed with High-Carbohydrate Diet or High-Fat Diet |
| Q55192876 | LiverSex Computational Model: Sexual Aspects in Hepatic Metabolism and Abnormalities. |
| Q91576706 | Longitudinal associations between ultra-processed foods and blood lipids in childhood |
| Q92505744 | Management of Diabetes Mellitus in Patients with Chronic Liver Diseases |
| Q47168175 | Maternal dietary free or bound fructose diversely influence developmental programming of lipogenesis. |
| Q59443140 | Mechanisms of NAFLD development and therapeutic strategies. |
| Q44303902 | MicroRNA-27a regulates hepatic lipid metabolism and alleviates NAFLD via repressing FAS and SCD1. |
| Q38806212 | Modeling fructose-load-induced hepatic de-novo lipogenesis by model simplification |
| Q61808513 | Neonatal intake of oleanolic acid attenuates the subsequent development of high fructose diet-induced non-alcoholic fatty liver disease in rats |
| Q28070168 | New Concepts on Pathogenesis and Diagnosis of Liver Fibrosis; A Review Article |
| Q30235846 | Non-alcoholic fatty liver disease: an emerging driving force in chronic kidney disease. |
| Q92363742 | Nonalcoholic fatty liver disease and the gut microbiome: Are bacteria responsible for fatty liver? |
| Q58783695 | PGC-1α in hepatic UPR during high-fat high-fructose diet and exercise training in mice |
| Q58800011 | Paeoniflorin Ameliorates Fructose-Induced Insulin Resistance and Hepatic Steatosis by Activating LKB1/AMPK and AKT Pathways |
| Q88674656 | Pathways and mechanisms linking dietary components to cardiometabolic disease: thinking beyond calories |
| Q93200077 | Preclinical Models for Studying NASH-Driven HCC: How Useful Are They? |
| Q92309434 | Prediabetes Induced by Fructose-Enriched Diet Influences Cardiac Lipidome and Proteome and Leads to Deterioration of Cardiac Function prior to the Development of Excessive Oxidative Stress and Cell Damage |
| Q37586657 | Regulatory landscape of AGE-RAGE-oxidative stress axis and its modulation by PPARγ activation in high fructose diet-induced metabolic syndrome |
| Q92435669 | Review article: emerging role of the gut microbiome in the progression of nonalcoholic fatty liver disease and potential therapeutic implications |
| Q89742823 | Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Liver-Targeting Acetyl-CoA Carboxylase Inhibitor (PF-05221304): A Three-Part Randomized Phase 1 Study |
| Q59792718 | Selenium-binding protein 1 (SELENBP1) is a marker of mature adipocytes |
| Q90279569 | Sex modifies the consequences of extended fructose consumption on liver health, motor function, and physiological damage in rats |
| Q47114574 | Sexual dimorphism in the hepatic protein response to a moderate trans fat diet in senescence-accelerated mice. |
| Q38782180 | Similarities and interactions between the ageing process and high chronic intake of added sugars |
| Q90351265 | Substitution of linoleic acid with α-linolenic acid or long chain n-3 polyunsaturated fatty acid prevents Western diet induced nonalcoholic steatohepatitis |
| Q99418706 | The mega-importance of de novo lipogenesis in platelet production |
| Q92861761 | The negative and detrimental effects of high fructose on the liver, with special reference to metabolic disorders |
| Q36044190 | The role of the gut microbiota in NAFLD. |
| Q97643745 | The small intestine shields the liver from fructose-induced steatosis |
| Q58802792 | Thiazolidinedione induces a therapeutic effect on hepatosteatosis by regulating stearoyl-CoA desaturase-1, lipase activity, leptin and resistin |
| Q90690372 | Transcriptome signature for dietary fructose-specific changes in rat renal cortex: A quantitative approach to physiological relevance |
| Q89014954 | Vegetarian diet, food substitution, and nonalcoholic fatty liver |
| Q56701573 | What Is the Optimal Dietary Composition for NAFLD? |
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