scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1022545215 |
P356 | DOI | 10.1038/376785A0 |
P953 | full work available online at | http://www.nature.com/articles/376785a0 |
http://www.nature.com/articles/376785a0.pdf | ||
P698 | PubMed publication ID | 7651539 |
P2093 | author name string | P. Pandey | |
D. W. Kufe | |||
R. R. Weichselbaum | |||
S. Kharbanda | |||
R. Ren | |||
S. M. Feller | |||
T. D. Shafman | |||
P2860 | cites work | Structural aspects of platinum anticancer drug interactions with DNA | Q60174164 |
Mechanism of monofunctional and bifunctional alkylation of DNA by mitomycin C | Q70394741 | ||
JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain | Q24308838 | ||
A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle | Q24319785 | ||
c-Abl kinase regulates the protein binding activity of c-Crk | Q24595669 | ||
Abl protein-tyrosine kinase selects the Crk adapter as a substrate using SH3-binding sites | Q28238659 | ||
SH2 and SH3 domains as molecular adhesives: the interactions of Crk and Abl | Q28307277 | ||
Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene | Q28512170 | ||
Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line | Q29547239 | ||
Production of high-titer helper-free retroviruses by transient transfection | Q29547802 | ||
Catalytic specificity of protein-tyrosine kinases is critical for selective signalling | Q29616451 | ||
The stress-activated protein kinase subfamily of c-Jun kinases | Q29620001 | ||
Phosphorylation of c-jun mediated by MAP kinases. | Q34947174 | ||
The nuclear tyrosine kinase c-Abl negatively regulates cell growth | Q42799874 | ||
Differential phosphorylation of c-Abl in cell cycle determined by cdc2 kinase and phosphatase activity. | Q46008782 | ||
Cell cycle-regulated binding of c-Abl tyrosine kinase to DNA | Q46126062 | ||
The UV response involving the Ras signaling pathway and AP-1 transcription factors is conserved between yeast and mammals | Q46508406 | ||
P433 | issue | 6543 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | mitogen-activated protein kinase kinases | Q6593810 |
mitogen-activated protein (MAP) kinase, JNK | Q24774703 | ||
P304 | page(s) | 785-788 | |
P577 | publication date | 1995-08-01 | |
1995-08-31 | |||
P1433 | published in | Nature | Q180445 |
P1476 | title | Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents | |
Activation of the c-Abl tyrosine kinase in the stress response to DMA-damaging agents | |||
P478 | volume | 376 |
Q30157529 | A crucial role in cell spreading for the interaction of Abl PxxP motifs with Crk and Nck adaptors |
Q33888587 | A cytoplasmic cell cycle controls the activity of a K+ channel in pre-implantation mouse embryos. |
Q48012149 | A deficiency in Syk enhances ceramide-induced apoptosis in DT40 lymphoma B cells |
Q33551475 | A non-Smad mechanism of fibroblast activation by transforming growth factor-beta via c-Abl and Egr-1: selective modulation by imatinib mesylate |
Q39079799 | A novel antitumor piperazine alkyl compound causes apoptosis by inducing RhoB expression via ROS‑mediated c‑Abl/p38 MAPK signaling |
Q40386894 | A nuclear tyrosine phosphorylation circuit: c-Jun as an activator and substrate of c-Abl and JNK. |
Q36017683 | A role for p300/CREB binding protein genes in promoting cancer progression in colon cancer cell lines with microsatellite instability |
Q59094153 | A sense-abl response? |
Q35625983 | ATM and ATR: sensing DNA damage. |
Q34425440 | ATM, a central controller of cellular responses to DNA damage. |
Q33771767 | ATM: a mediator of multiple responses to genotoxic stress |
Q42823498 | Activated c-Abl is degraded by the ubiquitin-dependent proteasome pathway |
Q38316514 | Activation of DNA-dependent protein kinase by single-stranded DNA ends |
Q33964540 | Activation of MEK kinase 1 by the c-Abl protein tyrosine kinase in response to DNA damage |
Q73934980 | Activation of PKCα Downstream from Caspases during Apoptosis Induced by 7-Hydroxystaurosporine or the Topoisomerase Inhibitors, Camptothecin and Etoposide, in Human Myeloid Leukemia HL60 Cells |
Q44177985 | Activation of SAPK/JNK signaling by protein kinase Cdelta in response to DNA damage |
Q24315773 | Activation of a human Ste20-like kinase by oxidant stress defines a novel stress response pathway |
Q38721357 | Activation of c-Abl Kinase Potentiates the Anti-myeloma Drug Lenalidomide by Promoting DDA1 Protein Recruitment to the CRL4 Ubiquitin Ligase |
Q54105065 | Activation of c-Abl tyrosine kinase requires caspase activation and is not involved in JNK/SAPK activation during apoptosis of human monocytic leukemia U937 cells |
Q41489968 | Activation of hematopoietic growth factor signal transduction pathways by the human oncogene BCR/ABL. |
Q41166239 | Activation of p38 mitogen-activated protein kinase by c-Abl-dependent and -independent mechanisms |
Q30175353 | Activation of the Abl tyrosine kinase in vivo by Src homology 3 domains from the Src homology 2/Src homology 3 adaptor Nck. |
Q47608162 | Active site-adjacent phosphorylation at Tyr-397 by c-Abl kinase inactivates caspase-9. |
Q83169213 | Advances in cellular and molecular radiation oncology |
Q43737676 | Age-specific changes in expression, activity, and activation of the c-Jun NH(2)-terminal kinase and p38 mitogen-activated protein kinases by methyl methanesulfonate in rats |
Q33959767 | Altered telomere nuclear matrix interactions and nucleosomal periodicity in ataxia telangiectasia cells before and after ionizing radiation treatment |
Q30176270 | An intramolecular SH3-domain interaction regulates c-Abl activity |
Q44401305 | Antagonistic Effects of ABL and BCRABL Proteins on Proliferation and the Response to Genotoxic Stress in Normal and Leukemic Myeloid Cells |
Q40657611 | Antioxidant ameliorates cisplatin-induced renal tubular cell death through inhibition of death receptor-mediated pathways |
Q77802842 | Apoptosis in the failing heart |
Q42162973 | Apoptosis resistance in tumor cells |
Q73434116 | Apoptosis-linked in vivo regulation of the tissue transglutaminase gene promoter |
Q36226739 | Apoptotic pathways and therapy resistance in human malignancies |
Q24315701 | ArgBP2, a Multiple Src Homology 3 Domain-containing, Arg/Abl-interacting Protein, Is Phosphorylated in v-Abl-transformed Cells and Localized in Stress Fibers and Cardiocyte Z-disks |
Q38289031 | Ascorbate up-regulates MLH1 (Mut L homologue-1) and p73: implications for the cellular response to DNA damage |
Q34909764 | Association of the ATM gene polymorphisms with papillary thyroid cancer |
Q29871427 | Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation |
Q33838181 | BUB3 that dissociates from BUB1 activates caspase-independent mitotic death (CIMD). |
Q40966218 | Bcl-xL blocks activation of related adhesion focal tyrosine kinase/proline-rich tyrosine kinase 2 and stress-activated protein kinase/c-Jun N-terminal protein kinase in the cellular response to methylmethane sulfonate |
Q44167851 | Bcr/Abl, leukemogenesis, and genomic instability: a complex partnership |
Q37875377 | Beyond ATM: The protein kinase landscape of the DNA damage response |
Q40583589 | Bidirectional signaling links the Abelson kinases to the platelet-derived growth factor receptor |
Q28249903 | Binding of Ku and c-Abl at the Kinase Homology Region of DNA-dependent Protein Kinase Catalytic Subunit |
Q73155209 | CL100/MKP-1 modulates JNK activation and apoptosis in response to cisplatin |
Q39674453 | Calpain-mediated Bid cleavage and calpain-independent Bak modulation: two separate pathways in cisplatin-induced apoptosis |
Q36627909 | Candidate protein biodosimeters of human exposure to ionizing radiation. |
Q38254387 | Caspase-9 as a therapeutic target for treating cancer |
Q37401482 | Cell cycle genes and ovarian cancer susceptibility: a tagSNP analysis |
Q34667098 | Cell signaling in aging and apoptosis |
Q34089685 | Cellular Responses to Cisplatin‐Induced DNA Damage |
Q29617899 | Cellular processing of platinum anticancer drugs |
Q24554382 | Characterization of a novel member of the DOK family that binds and modulates Abl signaling |
Q41515353 | Chemotherapy-induced apoptosis |
Q33788519 | Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer |
Q74613490 | Cisplatin-induced apoptosis by translocation of endogenous Bax in mouse collecting duct cells |
Q40689887 | Cisplatin-induced apoptosis in auditory cells: role of death receptor and mitochondrial pathways |
Q33179964 | Cisplatin-induced apoptotic cell death in Mongolian gerbil cochlea |
Q24318851 | Cockayne syndrome protein B interacts with and is phosphorylated by c-Abl tyrosine kinase |
Q24537451 | Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation |
Q34011009 | Controlling the Mdm2-Mdmx-p53 Circuit |
Q33698505 | Critical targets of protein kinase C in differentiation of tumour cells. |
Q33632975 | Cycling, stressed-out and nervous: cellular functions of c-Abl |
Q40631806 | Cyclopalladated compounds as chemotherapeutic agents: Antitumor activity against a murine melanoma cell line |
Q28143462 | Cytoskeletal protein PSTPIP1 directs the PEST-type protein tyrosine phosphatase to the c-Abl kinase to mediate Abl dephosphorylation |
Q38106985 | DNA Double-Strand Break Repair as Determinant of Cellular Radiosensitivity to Killing and Target in Radiation Therapy |
Q36324767 | DNA Repair--A Double-Edged Sword in the Genomic Stability of Cancer Cells--The Case of Chronic Myeloid Leukemia. |
Q58997314 | DNA damage enables p73 |
Q31427260 | Death signaling pathway induced by pyrrolidine dithiocarbamate-Cu(2+) complex in the cultured rat cortical astrocytes |
Q42509312 | Differential activation of mitogen-activated protein kinases by methyl methanesulfonate in the kidney of young and old rats |
Q41099165 | Distinctive functions of Syk and Lyn in mediating osmotic stress- and ultraviolet C irradiation-induced apoptosis in chicken B cells. |
Q38045474 | Does the small tyrosine kinase inhibitor imatinib mesylate counteract diabetes by affecting pancreatic islet amyloidosis and fibrosis? |
Q40893564 | Dominant-negative Jun N-terminal protein kinase (JNK-1) inhibits metabolic oxidative stress during glucose deprivation in a human breast carcinoma cell line |
Q40966703 | EAT/mcl-1, a member of the bcl-2 related genes, confers resistance to apoptosis induced by cis-diammine dichloroplatinum (II) via a p53-independent pathway |
Q33528959 | ER-alpha36, a variant of ER-alpha, promotes tamoxifen agonist action in endometrial cancer cells via the MAPK/ERK and PI3K/Akt pathways |
Q35101753 | Early growth response transcription factors: key mediators of fibrosis and novel targets for anti-fibrotic therapy |
Q36691949 | Effect of c-Abl tyrosine kinase on the cellular response to paclitaxel-induced microtubule damage |
Q28277030 | Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells |
Q41767263 | Enhancing CHK1 inhibitor lethality in glioblastoma |
Q28504693 | Essential roles for the Abl and Arg tyrosine kinases in neurulation |
Q28575987 | Fe65 is required for Tip60-directed histone H4 acetylation at DNA strand breaks |
Q73088388 | Function for p300 and not CBP in the apoptotic response to DNA damage |
Q28590355 | Functional interaction between DNA-PK and c-Abl in response to DNA damage |
Q24600427 | Functional interaction between RAFT1/FRAP/mTOR and protein kinase cdelta in the regulation of cap-dependent initiation of translation |
Q30175301 | Functional interaction between SHPTP1 and the Lyn tyrosine kinase in the apoptotic response to DNA damage |
Q24290639 | Functional interaction between c-Abl and the p21-activated protein kinase gamma-PAK |
Q28207612 | Functional interaction between the c-Abl and Arg protein-tyrosine kinases in the oxidative stress response |
Q34425450 | Functional interactions and signaling properties of mammalian DNA mismatch repair proteins |
Q33957163 | Functional role for protein kinase Cbeta as a regulator of stress-activated protein kinase activation and monocytic differentiation of myeloid leukemia cells |
Q41659051 | Functional role for the c-Abl protein tyrosine kinase in the cellular response to genotoxic stress |
Q30157957 | Fusion protein containing SH3 domain of c-Abl induces hepatocarcinoma cells to apoptosis |
Q38797526 | GADD45α modulates curcumin sensitivity through c-Abl- and JNK-dependent signaling pathways in a mismatch repair-dependent manner |
Q40734383 | Gene expression profiling by cDNA array in human hepatoma cell line in response to cisplatin treatment |
Q41157469 | Genotoxic drugs induce interaction of the c-Abl tyrosine kinase and the tumor suppressor protein p53. |
Q37588562 | Grape seed proanthocyanidin extract protects from cisplatin-induced nephrotoxicity by inhibiting endoplasmic reticulum stress-induced apoptosis |
Q42810871 | Growth inhibition by Abl requires an interplay of its SH2 and tyrosine kinase domains |
Q24314936 | HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway |
Q28138179 | Human 75-kDa DNA-pairing protein is identical to the pro-oncoprotein TLS/FUS and is able to promote D-loop formation |
Q24294875 | Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response |
Q28141846 | Human POMp75 is identified as the pro-oncoprotein TLS/FUS: both POMp75 and POMp100 DNA homologous pairing activities are associated to cell proliferation |
Q42709756 | Hyper-methylated miR-203 dysregulates ABL1 and contributes to the nickel-induced tumorigenesis |
Q41639296 | Hypothesis: Ataxia‐telangiectasia: Is ATM a sensor of oxidative damage and stress? |
Q34615934 | Identification and analysis of a hyperactive mutant form of Drosophila P-element transposase. |
Q38330988 | Impaired ionizing radiation-induced activation of a nuclear signal essential for phosphorylation of c-Jun by dually phosphorylated c-Jun amino-terminal kinases in ataxia telangiectasia fibroblasts |
Q36617515 | Induction of JNK and c-Abl signalling by cisplatin and oxaliplatin in mismatch repair-proficient and -deficient cells |
Q73692153 | Inhibition of Phosphatidylinositol 3-Kinase by c-Abl in the Genotoxic Stress Response |
Q40921673 | Inhibition of extracellular signal-regulated protein kinase or c-Jun N-terminal protein kinase cascade, differentially activated by cisplatin, sensitizes human ovarian cancer cell line |
Q46575255 | Integrin-mediated dendrite branch maintenance requires Abelson (Abl) family kinases. |
Q28239339 | Interaction between ATM protein and c-Abl in response to DNA damage |
Q31095720 | Interaction between UV-damaged DNA binding activity proteins and the c-Abl tyrosine kinase |
Q43559316 | Interaction of hematopoietic progenitor kinase 1 and c-Abl tyrosine kinase in response to genotoxic stress |
Q36076782 | Interleukin 8-stimulated phosphatidylinositol-3-kinase activity regulates the migration of human neutrophils independent of extracellular signal-regulated kinase and p38 mitogen-activated protein kinases |
Q28218739 | Involvement of TRAF4 in oxidative activation of c-Jun N-terminal kinase |
Q34997821 | Involvement of c-Abl, p53 and the MAP kinase JNK in the cell death program initiated in A2E-laden ARPE-19 cells by exposure to blue light |
Q36300473 | Isolation of full-length ATM cDNA and correction of the ataxia-telangiectasia cellular phenotype |
Q24294273 | JNK phosphorylation of 14-3-3 proteins regulates nuclear targeting of c-Abl in the apoptotic response to DNA damage |
Q53744555 | JNK/SAPK mediates doxorubicin-induced differentiation and apoptosis in MCF-7 breast cancer cells |
Q39147181 | KAT5 tyrosine phosphorylation couples chromatin sensing to ATM signalling |
Q77993726 | Lack of c-Jun activity increases survival to cisplatin |
Q28509902 | Late activation of stress kinases (SAPK/JNK) by genotoxins requires the DNA repair proteins DNA-PKcs and CSB |
Q41876225 | Late activation of stress-activated protein kinases/c-Jun N-terminal kinases triggered by cisplatin-induced DNA damage in repair-defective cells. |
Q74317765 | Lisofylline suppresses ex vivo release by murine spleen cells of hematopoietic inhibitors induced by cancer chemotherapeutic agents |
Q37459028 | Long-term Activation of c-Jun N-terminal Kinase through Receptor Interacting Protein is Associated with DNA Damage-induced Cell Death |
Q44104450 | MEK/ERK pathway protects ionizing radiation-induced loss of mitochondrial membrane potential and cell death in lymphocytic leukemia cells |
Q40084513 | MLH1- and ATM-dependent MAPK signaling is activated through c-Abl in response to the alkylator N-methyl-N'-nitro-N'-nitrosoguanidine |
Q36305476 | MLN4924 Synergistically Enhances Cisplatin-induced Cytotoxicity via JNK and Bcl-xL Pathways in Human Urothelial Carcinoma |
Q24298896 | MUC1 oncoprotein blocks nuclear targeting of c-Abl in the apoptotic response to DNA damage |
Q35503340 | MUC1 oncoprotein regulates Bcr-Abl stability and pathogenesis in chronic myelogenous leukemia cells |
Q34662602 | Male sterility and enhanced radiation sensitivity in TLS(-/-) mice |
Q38005668 | Mammalian MAPK Signal Transduction Pathways Activated by Stress and Inflammation: A 10-Year Update |
Q34802108 | Manganese-induced apoptosis in PC12 cells. |
Q52560042 | Mechanisms of radiation-induced gene responses |
Q34282241 | Mechanisms of resistance to cisplatin |
Q33946147 | Mechanisms of transformation by the BCR/ABL oncogene |
Q24601584 | Membrane-bound mucins: the mechanistic basis for alterations in the growth and survival of cancer cells |
Q47830356 | MicroRNA-203 suppresses proliferation in liver cancer associated with PIK3CA, p38 MAPK, c-Jun, and GSK3 signaling. |
Q41102936 | Mitogen-activated protein kinase cascades and regulation of gene expression |
Q39890068 | Mitogen-activated protein kinase phosphatase-1 modulated JNK activation is critical for apoptosis induced by inhibitor of epidermal growth factor receptor-tyrosine kinase |
Q30450695 | Modulation of DNA damage-induced apoptosis by cell adhesion is independently mediated by p53 and c-Abl. |
Q64389287 | Modulation of cellular response to ionizing radiation: towards new molecular targets? |
Q40935129 | Mutational status of the p53 gene modulates the basal level of jun N-terminal kinase and its inducibility by ultraviolet irradiation in A1-5 rat fibroblasts |
Q40235595 | NF-kappaB regulates the stability and activity of p73 by inducing its proteolytic degradation through a ubiquitin-dependent proteasome pathway |
Q28207707 | Negative Regulation of the SHPTP1 Protein Tyrosine Phosphatase by Protein Kinase C δ in Response to DNA Damage |
Q22010652 | Negative regulation of PYK2/related adhesion focal tyrosine kinase signal transduction by hematopoietic tyrosine phosphatase SHPTP1 |
Q40776013 | Nicotine affects the signaling of the death pathway, reducing the response of head and neck cancer cell lines to DNA damaging agents |
Q47891394 | Nitroxides Tempol and Tempo Induce Divergent Signal Transduction Pathways in MDA-MB 231 Breast Cancer Cells |
Q40809860 | Novel role for JNK as a stress-activated Bcl2 kinase |
Q28609906 | Nuclear export of the stress-activated protein kinase p38 mediated by its substrate MAPKAP kinase-2 |
Q41099672 | Nuclear tyrosine kinases: from Abl to WEE1. |
Q34047274 | Nuclear tyrosine phosphorylation: the beginning of a map. |
Q42315791 | Opposing roles of KIT and ABL1 in the therapeutic response of gastrointestinal stromal tumor (GIST) cells to imatinib mesylate. |
Q26862927 | Orchestrating B cell lymphopoiesis through interplay of IL-7 receptor and pre-B cell receptor signalling |
Q45875403 | Overexpression of manganese superoxide dismutase (MnSOD) in whole lung or alveolar type II cells of MnSOD transgenic mice does not provide intrinsic lung irradiation protection |
Q32144613 | Oxidative stress and c-Jun-amino-terminal kinase activation involved in apoptosis of primary astrocytes induced by disulfiram-Cu(2+) complex |
Q22011202 | PSK, a novel STE20-like kinase derived from prostatic carcinoma that activates the c-Jun N-terminal kinase mitogen-activated protein kinase pathway and regulates actin cytoskeletal organization |
Q36655956 | Parkinson's disease: a complex interplay of mitochondrial DNA alterations and oxidative stress |
Q35023172 | Persistent inhibition of ABL tyrosine kinase causes enhanced apoptotic response to TRAIL and disrupts the pro-apoptotic effect of chloroquine |
Q35849547 | Pharmacodynamics of cytarabine alone and in combination with 7-hydroxystaurosporine (UCN-01) in AML blasts in vitro and during a clinical trial |
Q24298958 | Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function |
Q34093159 | Phosphorylation in transcription: the CTD and more |
Q24305397 | Phosphorylation of DNA topoisomerase I by the c-Abl tyrosine kinase confers camptothecin sensitivity |
Q37549839 | Phosphorylation of the Mdm2 oncoprotein by the c-Abl tyrosine kinase regulates p53 tumor suppression and the radiosensitivity of mice |
Q37078179 | Post-treatment effects of erythropoietin and nordihydroguaiaretic acid on recovery from cisplatin-induced acute renal failure in the rat. |
Q41439150 | Potential molecular targets for manipulating the radiation response |
Q37626855 | Potential utility of small tyrosine kinase inhibitors in the treatment of diabetes |
Q42910099 | Programmed Cell Death of the Megagametophyte during Post-germinative Growth of White Spruce (Picea glauca) Seeds is Regulated by Reactive Oxygen Species and the Ubiquitin-mediated Proteolytic System |
Q39052637 | Protective effect of acetyl-l-carnitine against cisplatin ototoxicity: role of apoptosis-related genes and pro-inflammatory cytokines |
Q34360256 | Protective effect of cactus cladode extract against cisplatin induced oxidative stress, genotoxicity and apoptosis in balb/c mice: combination with phytochemical composition |
Q35037746 | Protein kinases and their involvement in the cellular responses to genotoxic stress. |
Q40932936 | Protein tyrosine kinase Lyn mediates apoptosis induced by topoisomerase II inhibitors in DT40 cells |
Q37210693 | Proteomics and pathway analysis identifies JNK signaling as critical for high linear energy transfer radiation-induced apoptosis in non-small lung cancer cells |
Q38215237 | Pulmonary complications of childhood cancers |
Q61483298 | Radioresistant Burkitt?s lymphoma cells exhibit defective MAPK signalling |
Q47770267 | Radiosensitivity and oxidative signalling in ataxia telangiectasia: an update |
Q33294129 | Reduced tumor growth in vivo and increased c-Abl activity in PC3 prostate cancer cells overexpressing the Shb adapter protein |
Q33765328 | Regulated phosphorylation of the RNA polymerase II C-terminal domain (CTD). |
Q41659032 | Regulation and function of the JNK subgroup of MAP kinases |
Q24320206 | Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase |
Q30176052 | Regulation of DNA-dependent Protein Kinase by the Lyn Tyrosine Kinase |
Q24336551 | Regulation of Rad51 Function by c-Abl in Response to DNA Damage |
Q34103653 | Regulation of cell death by the Abl tyrosine kinase |
Q24652254 | Regulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contexts |
Q40751506 | Regulation of p73 by c-Abl through the p38 MAP kinase pathway. |
Q43075879 | Regulation of p73-mediated apoptosis by c-Jun N-terminal kinase |
Q33601067 | Regulation of the DNA-dependent protein kinase (DNA-PK) activity in eukaryotic cells. |
Q39424924 | Regulation of the Mdm2-p53 signaling axis in the DNA damage response and tumorigenesis |
Q64388536 | Regulation of the hTERT telomerase catalytic subunit by the c-Abl tyrosine kinase |
Q28141152 | Regulation of the rapamycin and FKBP-target 1/mammalian target of rapamycin and cap-dependent initiation of translation by the c-Abl protein-tyrosine kinase |
Q36042664 | Relevance of atypical protein kinase C isotypes to the drug discovery process |
Q54663743 | Requirement for caspase activation in monocytic differentiation of myeloid leukemia cells |
Q42833330 | Requirement of caspase-mediated cleavage of c-Abl during stress-induced apoptosis |
Q33755493 | Rescue of Hippo coactivator YAP1 triggers DNA damage-induced apoptosis in hematological cancers. |
Q40802404 | Residual ataxia telangiectasia mutated protein function in cells from ataxia telangiectasia patients, with 5762ins137 and 7271T-->G mutations, showing a less severe phenotype. |
Q83524944 | Resveratrol Improves Hippocampal Atrophy in Chronic Fatigue Mice by Enhancing Neurogenesis and Inhibiting Apoptosis of Granular Cells |
Q44151433 | Retinoblastoma protein-mediated apoptosis after gamma-irradiation |
Q40732586 | Reversal of cisplatin resistance in human ovarian cancer cell lines by a c-jun antisense oligodeoxynucleotide (ISIS 10582): evidence for the role of transcription factor overexpression in determining resistant phenotype |
Q26782005 | Rho GTPases: Novel Players in the Regulation of the DNA Damage Response? |
Q22254596 | Role for Lyn tyrosine kinase as a regulator of stress-activated protein kinase activity in response to DNA damage |
Q41183906 | Role for c-Abl tyrosine kinase in growth arrest response to DNA damage. |
Q33957777 | Role for caspase-mediated cleavage of Rad51 in induction of apoptosis by DNA damage |
Q77800919 | Role for p300 in stabilization of p53 in the response to DNA damage |
Q28396643 | Role of ABL family kinases in cancer: from leukaemia to solid tumours |
Q43559235 | Role of ATM in oxidative stress-mediated c-Jun phosphorylation in response to ionizing radiation and CdCl2. |
Q36919677 | Role of Akt and c-Jun N-terminal Kinase 2 in Apoptosis Induced by Interleukin-4 Deprivation |
Q34333852 | Role of Bcl-xL/Beclin-1 in synergistic apoptotic effects of secretory TRAIL-armed adenovirus in combination with mitomycin C and hyperthermia on colon cancer cells |
Q35910747 | Role of DNA mismatch repair in apoptotic responses to therapeutic agents |
Q30164884 | Role of SHP-2 tyrosine phosphatase in the DNA damage-induced cell death response |
Q41515342 | Role of p53 in apoptosis. |
Q42527540 | Role of the stress-activated/c-Jun NH2-terminal protein kinase pathway in the cellular response to adriamycin and other chemotherapeutic drugs |
Q46857265 | Roles of volume-sensitive Cl- channel in cisplatin-induced apoptosis in human epidermoid cancer cells |
Q44414169 | SEK1-dependent JNK1 activation prolongs cell survival during G-Rh2-induced apoptosis |
Q35615838 | SHP-2 phosphatase is required for hematopoietic cell transformation by Bcr-Abl |
Q46784050 | SHP-2 phosphatase regulates DNA damage-induced apoptosis and G2/M arrest in catalytically dependent and independent manners, respectively |
Q34310555 | Shared pathways: death receptors and cytotoxic drugs in cancer therapy |
Q41750250 | Signal Transduction through MAP Kinase Cascades |
Q41679375 | Signal transduction by wild-type and leukemogenic Abl proteins. |
Q41228964 | Signal transduction pathways regulated by mitogen-activated/extracellular response kinase kinase kinase induce cell death |
Q41106742 | Sounding the alarm: protein kinase cascades activated by stress and inflammation |
Q40142360 | Stabilization of p73 by nuclear IkappaB kinase-alpha mediates cisplatin-induced apoptosis |
Q28307140 | Steel factor induces tyrosine phosphorylation of CRKL and binding of CRKL to a complex containing c-kit, phosphatidylinositol 3-kinase, and p120(CBL) |
Q39676953 | Sunitinib improves chemotherapeutic efficacy and ameliorates cisplatin-induced nephrotoxicity in experimental animals |
Q40664009 | Sustained activation of JNK/p38 MAPK pathways in response to cisplatin leads to Fas ligand induction and cell death in ovarian carcinoma cells |
Q41133285 | Syk-dependent and -independent signaling cascades in B cells elicited by osmotic and oxidative stress. |
Q21146439 | T cell receptor-independent basal signaling via Erk and Abl kinases suppresses RAG gene expression |
Q37286884 | TRAIL-induced apoptosis in gliomas is enhanced by Akt-inhibition and is independent of JNK activation |
Q53453867 | TTK/Mps1 controls nuclear targeting of c-Abl by 14-3-3-coupled phosphorylation in response to oxidative stress |
Q35782893 | Targeting mutated tyrosine kinases in the therapy of myeloid leukaemias |
Q28572770 | Targeting of the c-Abl tyrosine kinase to mitochondria in endoplasmic reticulum stress-induced apoptosis |
Q28207630 | The ARG tyrosine kinase interacts with Siva-1 in the apoptotic response to oxidative stress |
Q28206550 | The Abl family kinases: mechanisms of regulation and signaling |
Q40876650 | The BCR/ABL tyrosine kinase induces production of reactive oxygen species in hematopoietic cells |
Q40023085 | The Level of Intracellular Glutathione Is a Key Regulator for the Induction of Stress-Activated Signal Transduction Pathways Including Jun N-Terminal Protein Kinases and p38 Kinase by Alkylating Agents |
Q24606662 | The PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activity |
Q47096280 | The Role of MDM2 in Promoting Genome Stability versus Instability. |
Q34979711 | The activity and stability of the intrinsically disordered Cip/Kip protein family are regulated by non-receptor tyrosine kinases |
Q24649024 | The amphiphysin-like protein 1 (ALP1) interacts functionally with the cABL tyrosine kinase and may play a role in cytoskeletal regulation |
Q41751646 | The c-Abl tyrosine kinase contributes to the transient activation of MAP kinase in cells plated on fibronectin |
Q28508496 | The cytostatic function of c-Abl is controlled by multiple nuclear localization signals and requires the p53 and Rb tumor suppressor gene products |
Q37173931 | The effects of c-Abl mutation on developing B cell differentiation and survival |
Q22254262 | The evi-1 oncoprotein inhibits c-Jun N-terminal kinase and prevents stress-induced cell death |
Q40963201 | The presence of the Rb c-box peptide in the cytoplasm inhibits p210bcr-abl transforming function |
Q28611462 | The role of the stress-activated protein kinase (SAPK/JNK) signaling pathway in radiation-induced apoptosis |
Q30176902 | The stress response to ionizing radiation involoves c-Abl-dependent phosphorylation of SHPTP1. |
Q41200518 | The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat |
Q22010200 | The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage |
Q42807014 | Three distinct signalling responses by murine fibroblasts to genotoxic stress |
Q59054090 | Three paths to stress relief |
Q34616111 | Topoisomerase poisons activate the transcription factor NF-kappaB in ACH-2 and CEM cells |
Q38994070 | Trace levels of mitomycin C disrupt genomic integrity and lead to DNA damage response defect in long-term-cultured human embryonic stem cells |
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