scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1023854792 |
P356 | DOI | 10.1038/NATURE21079 |
P698 | PubMed publication ID | 28076346 |
P50 | author | Reinhard Georg Lührmann | Q1317944 |
Cindy L Will | Q63134178 | ||
Berthold Kastner | Q63134443 | ||
Henning Urlaub | Q28037184 | ||
Karl Bertram | Q41599411 | ||
P2093 | author name string | Holger Stark | |
Dmitry E Agafonov | |||
Klaus Hartmuth | |||
Olexandr Dybkov | |||
Wen-Ti Liu | |||
P2860 | cites work | Human step II splicing factor hSlu7 functions in restructuring the spliceosome between the catalytic steps of splicing | Q22009171 |
Cwc2 and its human homologue RBM22 promote an active conformation of the spliceosome catalytic centre | Q24301865 | ||
The crystal structure of PPIL1 bound to cyclosporine A suggests a binding mode for a linear epitope of the SKIP protein | Q24305898 | ||
Solution structure of human peptidyl prolyl isomerase-like protein 1 and insights into its interaction with SKIP | Q24314428 | ||
A human protein required for the second step of pre-mRNA splicing is functionally related to a yeast splicing factor | Q24314559 | ||
Genetic and physical interactions between factors involved in both cell cycle progression and pre-mRNA splicing in Saccharomyces cerevisiae | Q24548138 | ||
The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions | Q24595096 | ||
PHENIX: a comprehensive Python-based system for macromolecular structure solution | Q24654617 | ||
MolProbity: all-atom contacts and structure validation for proteins and nucleic acids | Q24684673 | ||
The architecture of the spliceosomal U4/U6.U5 tri-snRNP. | Q27316447 | ||
Crystal structure of Prp8 reveals active site cavity of the spliceosome | Q27676016 | ||
Structure of a yeast spliceosome at 3.6-angstrom resolution | Q27701867 | ||
The 3.8 Å structure of the U4/U6.U5 tri-snRNP: Insights into spliceosome assembly and catalysis | Q27703519 | ||
Molecular architecture of the human U4/U6.U5 tri-snRNP | Q27704181 | ||
Structure of a yeast activated spliceosome at 3.5 Å resolution | Q27721209 | ||
Structure of a yeast catalytic step I spliceosome at 3.4 Å resolution | Q27721261 | ||
Cryo-EM structure of the spliceosome immediately after branching | Q27722247 | ||
Molecular architecture of the Saccharomyces cerevisiae activated spliceosome | Q27727737 | ||
SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling | Q27860614 | ||
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei | Q27860728 | ||
Features and development of Coot | Q27861079 | ||
A U5 small nuclear ribonucleoprotein particle protein involved only in the second step of pre-mRNA splicing in Saccharomyces cerevisiae | Q27930011 | ||
Spliceosome activation by PRP2 ATPase prior to the first transesterification reaction of pre-mRNA splicing | Q27931041 | ||
Prp45 affects Prp22 partition in spliceosomal complexes and splicing efficiency of non-consensus substrates. | Q27932020 | ||
3D cryo-EM structure of an active step I spliceosome and localization of its catalytic core | Q41616762 | ||
GraFix: sample preparation for single-particle electron cryomicroscopy | Q41623539 | ||
Structural bioinformatics of the human spliceosomal proteome | Q42286114 | ||
Lysine-specific chemical cross-linking of protein complexes and identification of cross-linking sites using LC-MS/MS and the xQuest/xProphet software pipeline | Q42634194 | ||
Release of SF3 from the intron branchpoint activates the first step of pre-mRNA splicing | Q42914749 | ||
Requirement of the RNA helicase-like protein PRP22 for release of messenger RNA from spliceosomes | Q44165085 | ||
Suppression of multiple substrate mutations by spliceosomal prp8 alleles suggests functional correlations with ribosomal ambiguity mutants | Q47654036 | ||
Isolation of an active step I spliceosome and composition of its RNP core | Q50336090 | ||
Three-dimensional structure of C complex spliceosomes by electron microscopy. | Q51021603 | ||
The HAT helix, a repetitive motif implicated in RNA processing. | Q52561891 | ||
Structural basis of pre-mRNA splicing. | Q53378420 | ||
The U5 and U6 small nuclear RNAs as active site components of the spliceosome | Q64383669 | ||
U5 snRNA interacts with exon sequences at 5′ and 3′ splice sites | Q67753779 | ||
Functional domains of the yeast splicing factor Prp22p | Q73702880 | ||
Prp22, a DExH-box RNA helicase, plays two distinct roles in yeast pre-mRNA splicing | Q27934705 | ||
Prp2-mediated protein rearrangements at the catalytic core of the spliceosome as revealed by dcFCCS. | Q27935431 | ||
PRP16 is an RNA-dependent ATPase that interacts transiently with the spliceosome | Q27937219 | ||
Reconstitution of both steps of Saccharomyces cerevisiae splicing with purified spliceosomal components | Q27937542 | ||
Rearrangement of competing U2 RNA helices within the spliceosome promotes multiple steps in splicing | Q27939473 | ||
Identification and characterization of Prp45p and Prp46p, essential pre-mRNA splicing factors | Q27939548 | ||
Molecular dissection of step 2 catalysis of yeast pre-mRNA splicing investigated in a purified system | Q27939740 | ||
The spliceosome: design principles of a dynamic RNP machine | Q28131809 | ||
A large intrinsically disordered region in SKIP and its disorder-order transition induced by PPIL1 binding revealed by NMR | Q28910448 | ||
RELION: implementation of a Bayesian approach to cryo-EM structure determination | Q29547673 | ||
Visualizing density maps with UCSF Chimera | Q29619793 | ||
Identification of cross-linked peptides from complex samples. | Q30418939 | ||
RNA structure analysis of human spliceosomes reveals a compact 3D arrangement of snRNAs at the catalytic core | Q30556912 | ||
Characterization and functional ordering of Slu7p and Prp17p during the second step of pre-mRNA splicing in yeast | Q33863083 | ||
Semiquantitative proteomic analysis of the human spliceosome via a novel two-dimensional gel electrophoresis method | Q34181884 | ||
Crystal structure of a eukaryotic group II intron lariat | Q34339669 | ||
RNA catalyses nuclear pre-mRNA splicing | Q34382976 | ||
DEAH-box ATPase Prp16 has dual roles in remodeling of the spliceosome in catalytic steps | Q34415414 | ||
Organization of core spliceosomal components U5 snRNA loop I and U4/U6 Di-snRNP within U4/U6.U5 Tri-snRNP as revealed by electron cryomicroscopy | Q34575318 | ||
Evidence for a group II intron-like catalytic triplex in the spliceosome | Q34641230 | ||
A conformational rearrangement in the spliceosome sets the stage for Prp22-dependent mRNA release | Q34788134 | ||
ModeRNA: a tool for comparative modeling of RNA 3D structure | Q35017843 | ||
Allele-specific genetic interactions between Prp8 and RNA active site residues suggest a function for Prp8 at the catalytic core of the spliceosome. | Q35202911 | ||
Functional interactions of Prp8 with both splice sites at the spliceosomal catalytic center | Q35203137 | ||
Insights into the mechanisms of splicing: more lessons from the ribosome | Q36276514 | ||
Movies of ice-embedded particles enhance resolution in electron cryo-microscopy | Q36433748 | ||
Gel electrophoretic isolation of splicing complexes containing U1 small nuclear ribonucleoprotein particles | Q36783515 | ||
Spliceosomal DEAH-Box ATPases Remodel Pre-mRNA to Activate Alternative Splice Sites | Q37165431 | ||
The mechanism of the second step of pre-mRNA splicing | Q37947529 | ||
An essential splicing factor, SLU7, mediates 3' splice site choice in yeast | Q38324793 | ||
Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 Å resolution | Q38584680 | ||
The mammalian homologue of Prp16p is overexpressed in a cell line tolerant to Leflunomide, a new immunoregulatory drug effective against rheumatoid arthritis | Q41017180 | ||
Dissection of the factor requirements for spliceosome disassembly and the elucidation of its dissociation products using a purified splicing system | Q41553559 | ||
P433 | issue | 7641 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | spliceosome | Q915868 |
cryogenic electron microscopy | Q5190506 | ||
P304 | page(s) | 318-323 | |
P577 | publication date | 2017-01-11 | |
P1433 | published in | Nature | Q180445 |
P1476 | title | Cryo-EM structure of a human spliceosome activated for step 2 of splicing | |
P478 | volume | 542 |
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Q46170660 | Globular domain structure and function of restriction-like-endonuclease LINEs: similarities to eukaryotic splicing factor Prp8. |
Q47626728 | Human METTL16 is a N6-methyladenosine (m6A) methyltransferase that targets pre-mRNAs and various non-coding RNAs. |
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