Advances in bone marrow-derived cell therapy: CD31-expressing cells as next generation cardiovascular cell therapy

scientific article published on May 2011

Advances in bone marrow-derived cell therapy: CD31-expressing cells as next generation cardiovascular cell therapy is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2217/RME.11.24
P932PMC publication ID3129287
P698PubMed publication ID21548739
P5875ResearchGate publication ID51104192

P2093author name stringYoung-sup Yoon
Sung-Whan Kim
Hyongbum Kim
P2860cites workRegenerating the heartQ22251075
PECAM-1 (CD31) Cloning and Relation to Adhesion Molecules of the Immunoglobulin Gene SuperfamilyQ24299656
A mechanosensitive transcriptional mechanism that controls angiogenesisQ24314809
Cardiac repair with intramyocardial injection of allogeneic mesenchymal stem cells after myocardial infarctionQ24534652
Origins of circulating endothelial cells and endothelial outgrowth from bloodQ24599869
Molecular and cellular properties of PECAM-1 (endoCAM/CD31): a novel vascular cell-cell adhesion moleculeQ24644205
Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cellsQ24672061
Bone marrow-derived endothelial progenitor cells are a major determinant of nascent tumor neovascularizationQ24673319
Multilineage potential of adult human mesenchymal stem cellsQ27860737
Stem cells, cancer, and cancer stem cellsQ27860878
Stem CellsQ28111899
A perivascular origin for mesenchymal stem cells in multiple human organsQ28131808
Stem cells: units of development, units of regeneration, and units in evolutionQ28143314
Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cellQ28188430
Impaired recruitment of bone-marrow–derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growthQ28203327
Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytesQ28209232
Bone marrow cells regenerate infarcted myocardiumQ28210640
Transplantation of Progenitor Cells and Regeneration Enhancement in Acute Myocardial Infarction (TOPCARE-AMI)Q28216990
Endothelial progenitor cells control the angiogenic switch in mouse lung metastasisQ28264314
Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord bloodQ28269379
Isolation of putative progenitor endothelial cells for angiogenesisQ28302884
Heart disease and stroke statistics--2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics SubcommitteeQ28303699
Functional neurogenesis in the adult hippocampusQ29618708
Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuliQ29618769
Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivoQ29619355
Mobilization of bone marrow-derived cells enhances the angiogenic response to hypoxia without transdifferentiation into endothelial cellsQ30438261
Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarctionQ30824170
Determinants of functional recovery after myocardial infarction of patients treated with bone marrow-derived stem cells after thrombolytic therapyQ30883977
Clinical outcome 2 years after intracoronary administration of bone marrow-derived progenitor cells in acute myocardial infarctionQ30968626
Bone marrow-derived cells do not incorporate into the adult growing vasculature.Q31031009
Paracrine action accounts for marked protection of ischemic heart by Akt-modified mesenchymal stem cellsQ47820046
Local delivery of marrow-derived stromal cells augments collateral perfusion through paracrine mechanismsQ47945142
Intracoronary infusion of CD133+ endothelial progenitor cells improves heart function and quality of life in patients with chronic post-infarct heart insufficiencyQ48257019
Regenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens.Q48414650
Human umbilical cord blood-derived CD133+ cells enhance function and repair of the infarcted myocardiumQ48944721
Evidence that intracoronary-injected CD133+ peripheral blood progenitor cells home to the myocardium in chronic postinfarction heart failureQ50894332
Intramyocardial transplantation of autologous CD34+ stem cells for intractable angina: a phase I/IIa double-blind, randomized controlled trialQ50981942
Spontaneous transformation of cultured mouse bone marrow-derived stromal cellsQ51104088
Soluble factors released by endothelial progenitor cells promote migration of endothelial cells and cardiac resident progenitor cellsQ51345347
Extracardiac progenitor cells repopulate most major cell types in the transplanted human heartQ51833240
Heart transplantation in a 68-year-old patient with senile systemic amyloidosisQ51931372
Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptideQ52008649
Dystrophin expression in the mdx mouse restored by stem cell transplantationQ52174025
Accumulated chromosomal instability in murine bone marrow mesenchymal stem cells leads to malignant transformation.Q53352599
Impact of implanted bone marrow progenitor cell composition on limb salvage after cell implantation in patients with critical limb ischemiaQ53371543
Unexpected severe calcification after transplantation of bone marrow cells in acute myocardial infarctionQ53638713
Critical roles of muscle-secreted angiogenic factors in therapeutic neovascularization.Q55041759
Autologous bone marrow-derived stem-cell transfer in patients with ST-segment elevation myocardial infarction: double-blind, randomised controlled trialQ56610959
Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarctsQ59064540
Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusionQ59064568
Human cardiomyocyte progenitor cell transplantation preserves long-term function of the infarcted mouse myocardiumQ59196002
Lymphocyte-endothelial cell adhesion molecules at the primary tumor site in human lung and renal cell carcinomasQ72068235
Peripheral blood "endothelial progenitor cells" are derived from monocyte/macrophages and secrete angiogenic growth factorsQ73075799
Endothelial cell tube formation depends on cadherin 5 and CD31 interactions with filamentous actinQ73271340
Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survivalQ73755005
Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted heartsQ73791469
Chimerism of the Transplanted HeartQ77452324
Evidence for cardiomyocyte repopulation by extracardiac progenitors in transplanted human heartsQ77885470
Transdifferentiation of Human Peripheral Blood CD34 + -Enriched Cell Population Into Cardiomyocytes, Endothelial Cells, and Smooth Muscle Cells In VivoQ79186612
CD34-positive cells exhibit increased potency and safety for therapeutic neovascularization after myocardial infarction compared with total mononuclear cellsQ79317344
Intracoronary injection of autologous bone marrow-derived mononuclear cells in patients with large anterior acute myocardial infarction: a prematurely terminated randomized studyQ80485648
Intracoronary transplantation of non-expanded peripheral blood-derived mononuclear cells promotes improvement of cardiac function in patients with acute myocardial infarctionQ80673912
Synergistic neovascularization by mixed transplantation of early endothelial progenitor cells and late outgrowth endothelial cells: the role of angiogenic cytokines and matrix metalloproteinasesQ81168941
Improved graft mesenchymal stem cell survival in ischemic heart with a hypoxia-regulated heme oxygenase-1 vectorQ81297170
Umbilical cord mesenchymal stem cells: role of regulatory genes in their differentiation to osteoblastsQ83151420
Bone marrow stem cells prevent left ventricular remodeling of ischemic heart through paracrine signalingQ83323467
Intracoronary bone marrow cell transfer after myocardial infarction: eighteen months' follow-up data from the randomized, controlled BOOST (BOne marrOw transfer to enhance ST-elevation infarct regeneration) trialQ31033745
PECAM-1 shedding during apoptosis generates a membrane-anchored truncated molecule with unique signaling characteristicsQ31825950
Monocytes coexpress endothelial and macrophagocytic lineage markers and form cord-like structures in Matrigel under angiogenic conditionsQ33181601
Bone marrow-derived hematopoietic cells generate cardiomyocytes at a low frequency through cell fusion, but not transdifferentiationQ33202256
Dual angiogenic and neurotrophic effects of bone marrow-derived endothelial progenitor cells on diabetic neuropathyQ33403153
Human CD133+ progenitor cells promote the healing of diabetic ischemic ulcers by paracrine stimulation of angiogenesis and activation of Wnt signalingQ33649290
Unchain my heart: the scientific foundations of cardiac repairQ33683767
Clonally expanded novel multipotent stem cells from human bone marrow regenerate myocardium after myocardial infarctionQ33777861
Cardiomyocytes can be generated from marrow stromal cells in vitroQ33843659
Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularizationQ33870103
Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursorsQ33887795
From marrow to brain: expression of neuronal phenotypes in adult mice.Q33926766
Human CD34+ cells in experimental myocardial infarction: long-term survival, sustained functional improvement, and mechanism of actionQ34012519
Endothelial cell apoptosis in angiogenesis and vessel regressionQ34033870
Human adult vena saphena contains perivascular progenitor cells endowed with clonogenic and proangiogenic potentialQ34051091
Human peripheral blood-derived CD31+ cells have robust angiogenic and vasculogenic properties and are effective for treating ischemic vascular diseaseQ34051561
Isolated allogeneic bone marrow-derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: Implications for cell therapy of boneQ34066339
Neuropilin-1 is required for vascular development and is a mediator of VEGF-dependent angiogenesis in zebrafishQ34074705
Survival and development of neonatal rat cardiomyocytes transplanted into adult myocardiumQ34114690
CD31+ cells represent highly angiogenic and vasculogenic cells in bone marrow: novel role of nonendothelial CD31+ cells in neovascularization and their therapeutic effects on ischemic vascular diseaseQ34125508
Tie receptors: new modulators of angiogenic and lymphangiogenic responsesQ34205564
Cardiac progenitor cells and bone marrow-derived very small embryonic-like stem cells for cardiac repair after myocardial infarctionQ34334027
VasculogenesisQ34387300
Randomized transcoronary delivery of CD34(+) cells with perfusion versus stop-flow method in patients with recent myocardial infarction: Early cardiac retention of ⁹⁹(m)Tc-labeled cells activityQ34544884
A granulocyte-macrophage colony-stimulating factor and interleukin-15 fusokine induces a regulatory B cell population with immune suppressive properties.Q34996561
Transplantation of ex vivo expanded endothelial progenitor cells for therapeutic neovascularizationQ35111623
Wharton's jelly-derived cells are a primitive stromal cell populationQ35849157
Clinical applications of stem cells for the heartQ36030311
Unresolved questions, changing definitions, and novel paradigms for defining endothelial progenitor cellsQ36132926
Immunogenicity of adult mesenchymal stem cells: lessons from the fetal allograft.Q36169728
Role of host tissues for sustained humoral effects after endothelial progenitor cell transplantation into the ischemic heartQ36294424
PECAM-1 is required for transendothelial migration of leukocytesQ36362038
Molecular cloning and adhesive properties of murine platelet/endothelial cell adhesion molecule 1.Q36364434
A randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (prochymal) after acute myocardial infarctionQ36634299
Immune plasticity of bone marrow-derived mesenchymal stromal cellsQ36842407
PECAM-1: a multi-functional molecule in inflammation and vascular biologyQ36943068
Cell therapy in peripheral arterial diseaseQ37279639
Bone marrow mononuclear cells have neurovascular tropism and improve diabetic neuropathyQ37352703
Adipose tissue-derived stem cells: characterization and potential for cardiovascular repairQ37560486
COMP-Ang1: a designed angiopoietin-1 variant with nonleaky angiogenic activityQ37681973
Mesenchymal Stem Cell Therapy for Cardiac RepairQ37777383
Monocytes stimulate expression of the Bcl-2 family member, A1, in endothelial cells and confer protection against apoptosisQ38328396
Characterization and functionality of cell surface molecules on human mesenchymal stem cellsQ38357443
Unblinded pilot study of autologous transplantation of bone marrow mononuclear cells in patients with thromboangiitis obliteransQ39342745
Circulating endothelial progenitor cells, vascular function, and cardiovascular riskQ39513285
HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathwayQ39946864
Intramuscular transplantation of G-CSF-mobilized CD34(+) cells in patients with critical limb ischemia: a phase I/IIa, multicenter, single-blinded, dose-escalation clinical trialQ39951889
Sarcoma derived from cultured mesenchymal stem cellsQ40220522
Effects of intracoronary infusion of peripheral blood stem-cells mobilised with granulocyte-colony stimulating factor on left ventricular systolic function and restenosis after coronary stenting in myocardial infarction: the MAGIC cell randomised clQ40525372
Intramyocardial transplantation of autologous endothelial progenitor cells for therapeutic neovascularization of myocardial ischemiaQ40608302
Gene therapy strategy for long-term myocardial protection using adeno-associated virus-mediated delivery of heme oxygenase geneQ40662320
Involvement of human PECAM-1 in angiogenesis and in vitro endothelial cell migrationQ40739492
Changing potency by spontaneous fusion.Q40740330
Implantation of bone marrow mononuclear cells into ischemic myocardium enhances collateral perfusion and regional function via side supply of angioblasts, angiogenic ligands, and cytokinesQ40783492
Adhesion molecules involved in transendothelial migration of human hematopoietic progenitor cellsQ40843286
Endothelial-like cells derived from human CD14 positive monocytes.Q40863903
Involvement of endothelial PECAM-1/CD31 in angiogenesisQ42087882
Roles of platelet/endothelial cell adhesion molecule-1 (PECAM-1, CD31) in natural killer cell transendothelial migration and beta 2 integrin activation.Q42816537
Interleukin-8 as a macrophage-derived mediator of angiogenesisQ44053300
Angiopoietin-regulated recruitment of vascular smooth muscle cells by endothelial-derived heparin binding EGF-like growth factorQ44575195
Amniotic fluid as a rich source of mesenchymal stromal cells for transplantation therapyQ45347085
Long-term clinical outcomes for patients with lower limb ischemia implanted with G-CSF-mobilized autologous peripheral blood mononuclear cellsQ45744623
Muscle regeneration by bone marrow-derived myogenic progenitorsQ45885806
Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardiumQ46057122
Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanismsQ47248012
Reduction of myocardial scar size after implantation of mesenchymal stem cells in rats: what is the mechanism?Q47377559
Diverse origin and function of cells with endothelial phenotype obtained from adult human blood.Q47398233
Evidence for circulating bone marrow-derived endothelial cellsQ47612637
P433issue3
P304page(s)335-349
P577publication date2011-05-01
P1433published inRegenerative MedicineQ19921466
P1476titleAdvances in bone marrow-derived cell therapy: CD31-expressing cells as next generation cardiovascular cell therapy
P478volume6

Reverse relations

cites work (P2860)
Q49475284CD34- human placenta-derived mesenchymal stem cells protect against heat stroke mortality in rats
Q35916753Chronic endurance exercise affects paracrine action of CD31+ and CD34+ cells on endothelial tube formation
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Q87310781Effect of calycosin on left ventricular ejection fraction and angiogenesis in rat models with myocardial infarction
Q53355573Endothelial Differentiation and Vasculogenesis Induced by Three‐Dimensional Adipose‐Derived Stem Cells
Q39133326Endothelial cell markers from clinician's perspective.
Q92500962Exercise and Cardiovascular Progenitor Cells
Q92481678Immune cell extracellular vesicles and their mitochondrial content decline with ageing
Q50436947Improved revascularization of islet grafts using an angiogenic monocyte subpopulation derived from spheroid culture of bone marrow mononuclear cells
Q48037777Investigating the extremes of the continuum of paracrine functions in CD34-/CD31+ CACs across diverse populations
Q35684128Isolation of Foreign Material-Free Endothelial Progenitor Cells Using CD31 Aptamer and Therapeutic Application for Ischemic Injury
Q53727483Mitochondria-specific antioxidant supplementation does not influence endurance exercise training-induced adaptations in circulating angiogenic cells, skeletal muscle oxidative capacity or maximal oxygen uptake
Q34256907Overexpression of angiopoietin-1 increases CD133+/c-kit+ cells and reduces myocardial apoptosis in db/db mouse infarcted hearts
Q37593811Prognostic significance of circulating and endothelial progenitor cell markers in type 2 diabetic foot.
Q53666140The role of eNOS in the migration and proliferation of bone-marrow derived endothelial progenitor cells and in vitro angiogenesis

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