The RelA nuclear localization signal folds upon binding to IκBα.

scientific article published on 19 November 2010

The RelA nuclear localization signal folds upon binding to IκBα. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.JMB.2010.10.055
P932PMC publication ID3056351
P698PubMed publication ID21094161
P5875ResearchGate publication ID49625377

P50authorH. Jane DysonQ30513249
Magnus KjaergaardQ42129953
P2093author name stringElizabeth A Komives
Simon Bergqvist
Carla F Cervantes
Shih-Che Sue
Gerard Kroon
P2860cites workStructure of an IkappaBalpha/NF-kappaB complexQ22008582
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Structure of the Minimal Interface Between ApoE and LRPQ27660292
The role of DNA in the mechanism of NFkappaB dimer formation: crystal structures of the dimerization domains of the p50 and p65 subunitsQ27748097
Crystal structure of p50/p65 heterodimer of transcription factor NF-kappaB bound to DNAQ27748829
The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NF-kappaB inactivationQ27766393
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Phosphorylation meets ubiquitination: the control of NF-[kappa]B activityQ27860643
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Nuclear targeting sequences--a consensus?Q27860997
NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responsesQ27861101
Ikappa Balpha functions through direct contacts with the nuclear localization signals and the DNA binding sequences of NF-kappaBQ28282499
Molecular recognition via coupled folding and binding in a TPR domainQ28910476
Rapid measurement of binding constants and heats of binding using a new titration calorimeterQ29547842
Activators and target genes of Rel/NF-kappaB transcription factorsQ29547882
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Coupling of local folding to site-specific binding of proteins to DNAQ29616464
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Backbone dynamics of Escherichia coli ribonuclease HI: correlations with structure and function in an active enzymeQ29616524
Sequence requirements for nuclear location of simian virus 40 large-T antigenQ29620588
Induced fit, folding, and recognition of the NF-kappaB-nuclear localization signals by IkappaBalpha and IkappaBbeta.Q30359466
Binding in the growth hormone receptor complexQ33593803
Genetic approaches in mice to understand Rel/NF-kappaB and IkappaB function: transgenics and knockoutsQ33797150
Construction and characterization of an SV40 mutant defective in nuclear transport of T antigen.Q34054639
Structure and mechanism in NF-kappa B/I kappa B signalingQ34170945
Characterization of the three-dimensional solution structure of human profilin: 1H, 13C, and 15N NMR assignments and global folding patternQ34346858
Regions of IkappaBalpha that are critical for its inhibition of NF-kappaB.DNA interaction fold upon binding to NF-kappaBQ35539707
Identification of the human c-myc protein nuclear translocation signalQ36846194
Folding landscapes of ankyrin repeat proteins: experiments meet theoryQ37075180
The IkappaBalpha/NF-kappaB complex has two hot spots, one at either end of the interfaceQ41492776
Functional dynamics of the folded ankyrin repeats of I kappa B alpha revealed by nuclear magnetic resonanceQ42097999
Distinct roles of IkappaB proteins in regulating constitutive NF-kappaB activity.Q42483415
A homeostatic model of IkappaB metabolism to control constitutive NF-kappaB activityQ42512304
Thermodynamics reveal that helix four in the NLS of NF-kappaB p65 anchors IkappaBalpha, forming a very stable complex.Q43130560
Sequence-dependent correction of random coil NMR chemical shiftsQ43677693
Structural and dynamic characterization of intrinsically disordered human securin by NMR spectroscopyQ45324865
Global Folds of Highly Deuterated, Methyl-Protonated Proteins by Multidimensional NMR†Q57851041
Dissection of the karyopherin alpha nuclear localization signal (NLS)-binding groove: functional requirements for NLS bindingQ73806566
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)754-764
P577publication date2010-11-19
P1433published inJournal of Molecular BiologyQ925779
P1476titleThe RelA nuclear localization signal folds upon binding to IκBα.
P478volume405

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Q34765931Inhibition of UII/UTR system relieves acute inflammation of liver through preventing activation of NF-κB pathway in ALF mice
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Q64033774The isolated C-terminal nuclear localization sequence of the breast cancer metastasis suppressor 1 is disordered

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