The requirement of IRE1 and XBP1 in resolving physiological stress during Drosophila development

scientific article published on 3 August 2017

The requirement of IRE1 and XBP1 in resolving physiological stress during Drosophila development is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1242/JCS.203612
P932PMC publication ID5612175
P698PubMed publication ID28775151

P50authorDavid RonQ18195722
Hyung Don RyooQ61009980
P2093author name stringTaiyoun Rhim
Huai-Wei Huang
Xiaomei Zeng
P2860cites workCoupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1Q22011167
XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel diseaseQ22252318
Plasma cell differentiation requires the transcription factor XBP-1Q24291453
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factorQ24292102
Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans developmentQ24292104
Unfolded protein response in a Drosophila model for retinal degenerationQ24682908
Drosophila as a model for unfolded protein response researchQ26863590
Structure of the Dual Enzyme Ire1 Reveals the Basis for Catalysis and Regulation in Nonconventional RNA SplicingQ27649529
The unfolded protein response signals through high-order assembly of Ire1Q27653139
Structural and functional basis for RNA cleavage by Ire1Q27670676
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNAQ28214814
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glandsQ28510479
Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survivalQ28593963
The unfolded protein response: from stress pathway to homeostatic regulationQ29547396
Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesisQ29615747
Paneth cells as a site of origin for intestinal inflammation.Q30559414
A genetic screen in Drosophila reveals novel cytoprotective functions of the autophagy-lysosome pathwayQ33475622
An essential role for XBP-1 in host protection against immune activation in C. elegansQ33710158
A drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathwayQ33888386
On the mechanism of sensing unfolded protein in the endoplasmic reticulumQ34230593
P[acman]: a BAC transgenic platform for targeted insertion of large DNA fragments in D. melanogaster.Q34586256
Innate immune homeostasis by the homeobox gene caudal and commensal-gut mutualism in Drosophila.Q34740991
Messenger RNA targeting to endoplasmic reticulum stress signalling sites.Q34903088
Drosophila XBP1 expression reporter marks cells under endoplasmic reticulum stress and with high protein secretory loadQ35010090
The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein responseQ35029280
Induction of excessive endoplasmic reticulum stress in the Drosophila male accessory gland results in infertility.Q35151224
CDK5 and MEKK1 mediate pro-apoptotic signalling following endoplasmic reticulum stress in an autosomal dominant retinitis pigmentosa modelQ35870707
Membrane lipid saturation activates endoplasmic reticulum unfolded protein response transducers through their transmembrane domainsQ36712468
A modified UPR stress sensing system reveals a novel tissue distribution of IRE1/XBP1 activity during normal Drosophila developmentQ36780339
Using natural variation in Drosophila to discover previously unknown endoplasmic reticulum stress genesQ36895564
EGFR signaling regulates the proliferation of Drosophila adult midgut progenitorsQ37205147
Regulated Ire1-dependent decay of messenger RNAs in mammalian cellsQ37309146
Function of IRE1 alpha in the placenta is essential for placental development and embryonic viabilityQ37377347
Xbp1-independent Ire1 signaling is required for photoreceptor differentiation and rhabdomere morphogenesis in DrosophilaQ37381743
4E-BP is a target of the GCN2-ATF4 pathway during Drosophila development and agingQ37576581
Insect seminal fluid proteins: identification and functionQ37587506
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response.Q38311676
Membrane aberrancy and unfolded proteins activate the endoplasmic reticulum stress sensor Ire1 in different waysQ38394944
Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein responseQ38845249
Intestinal IRE1 Is Required for Increased Triglyceride Metabolism and Longer Lifespan under Dietary RestrictionQ41642408
Ablation of insulin-producing neurons in flies: growth and diabetic phenotypesQ43988822
Relish, a central factor in the control of humoral but not cellular immunity in DrosophilaQ45007881
Brummer lipase is an evolutionary conserved fat storage regulator in DrosophilaQ47070072
A putative digestive cysteine proteinase from Drosophila melanogaster is predominantly expressed in the embryonic and larval midgutQ48075555
Synthesis of two Drosophila male accessory gland proteins and their fate after transfer to the female during mating.Q52239400
Characterization of Myosin-IA and Myosin-IB, Two Unconventional Myosins Associated with theDrosophilaBrush Border CytoskeletonQ52537092
P4510describes a project that usesCytoscapeQ3699942
DESeq2Q113018293
P433issue18
P407language of work or nameEnglishQ1860
P921main subjectDrosophilaQ312154
P304page(s)3040-3049
P577publication date2017-08-03
P1433published inJournal of Cell ScienceQ1524177
P1476titleThe requirement of IRE1 and XBP1 in resolving physiological stress during Drosophila development
P478volume130

Reverse relations

cites work (P2860)
Q58799768Baldspot/ELOVL6 is a conserved modifier of disease and the ER stress response
Q89664044Decoupling of Apoptosis from Activation of the ER Stress Response by the Drosophila Metallopeptidase superdeath
Q91633568The unfolded protein response in metazoan development
Q41997586Unfolded protein response transducer IRE1-mediated signaling independent of XBP1 mRNA splicing is not required for growth and development of medaka fish

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