Wikidata entity: Q425729

C₂₇H₃₆N₂O₅ (P274)


Wikimedia Commons category is Ivabradine

Contact

P856official websitehttps://www.corlanorhcp.com

Quantities

P4250defined daily dose10
P2067mass468.262422

P3780 active ingredient in ... Q47521405 (Corlanor) Corlanor
P233 canonical SMILES String CN(CCCN1CCC2=CC(=C(C=C2CC1=O)OC)OC)CC3CC4=CC(=C(C=C34)OC)OC ???
P373 Commons category String Ivabradine ???
P366 has use ... Q12140 (medication) medication
P31 instance of ... Q113145171 (type of chemical entity) type of chemical entity
P2017 isomeric SMILES String CN(CCCN1CCC2=CC(=C(C=C2CC1=O)OC)OC)C[C@H]3CC4=CC(=C(C=C34)OC)OC ???
P8026 LiverTox likelihood score ... Q83284667 (LiverTox toxicity likelihood category E) LiverTox toxicity likelihood category E
P2175 medical condition treated ... Q847583 (cardiomyopathy) cardiomyopathy
P2175 medical condition treated ... Q19000661 (congestive heart failure) congestive heart failure
P129 physically interacts with ... Q21115989 (Hyperpolarization activated cyclic nucleotide gated potassium channel 1) Hyperpolarization activated cyclic nucleotide gated potassium channel 1
P129 physically interacts with ... Q21115996 (Hyperpolarization activated cyclic nucleotide gated potassium channel 3) Hyperpolarization activated cyclic nucleotide gated potassium channel 3
P129 physically interacts with ... Q21115998 (Hyperpolarization activated cyclic nucleotide gated potassium channel 4) Hyperpolarization activated cyclic nucleotide gated potassium channel 4
P129 physically interacts with ... Q21982207 (Hyperpolarization-activated, cyclic nucleotide-gated K+ 2) Hyperpolarization-activated, cyclic nucleotide-gated K+ 2
P129 physically interacts with ... Q21982210 (Hyperpolarization activated cyclic nucleotide gated potassium channel 1) Hyperpolarization activated cyclic nucleotide gated potassium channel 1
P3489 pregnancy category ... Q3679274 (Australian pregnancy category D) Australian pregnancy category D
P636 route of administration ... Q285166 (oral administration) oral administration
P769 significant drug interaction ... Q7739 (arsenic trioxide) arsenic trioxide
P769 significant drug interaction ... Q118551 (clarithromycin) clarithromycin
P769 significant drug interaction ... Q144085 (pimozide) pimozide
P769 significant drug interaction ... Q174259 (droperidol) droperidol
P769 significant drug interaction ... Q179996 ((RS)-methadone) (RS)-methadone
P769 significant drug interaction ... Q213511 (erythromycin) erythromycin
P769 significant drug interaction ... Q228143 (zuclopenthixol) zuclopenthixol
P769 significant drug interaction ... Q251347 (haloperidol) haloperidol
P769 significant drug interaction ... Q407883 (ketoconazole) ketoconazole
P769 significant drug interaction ... Q407972 (chlorpromazine) chlorpromazine
P769 significant drug interaction ... Q408637 (dronedarone) dronedarone
P769 significant drug interaction ... Q409672 ((RS)-citalopram) (RS)-citalopram
P769 significant drug interaction ... Q410061 (amiodarone) amiodarone
P769 significant drug interaction ... Q410291 (verapamil) verapamil
P769 significant drug interaction ... Q411229 (itraconazole) itraconazole
P769 significant drug interaction ... Q412236 (voriconazole) voriconazole
P769 significant drug interaction ... Q421937 ((RS)-hydroxyzine) (RS)-hydroxyzine
P769 significant drug interaction ... Q422229 (diltiazem) diltiazem
P769 significant drug interaction ... Q412690 (galantamine) galantamine
P769 significant drug interaction ... Q413591 (sotalol) sotalol
P769 significant drug interaction ... Q415081 (donepezil) donepezil
P769 significant drug interaction ... Q422418 ((RS)-sulpiride) (RS)-sulpiride
P769 significant drug interaction ... Q422618 (ritonavir) ritonavir
P769 significant drug interaction ... Q424940 (moxifloxacin) moxifloxacin
P769 significant drug interaction ... Q425120 (disopyramide) disopyramide
P769 significant drug interaction ... Q425137 (fingolimod) fingolimod
P769 significant drug interaction ... Q906453 (posaconazole) posaconazole
P769 significant drug interaction ... Q3896970 (pasireotide) pasireotide
P769 significant drug interaction ... Q3993743 ((Z)-Toremifene) (Z)-Toremifene
P769 significant drug interaction ... Q5186964 (crizotinib) crizotinib
P769 significant drug interaction ... Q5473363 (fosphenytoin) fosphenytoin
P769 significant drug interaction ... Q7914515 (vandetanib) vandetanib
P3364 stereoisomer of ... Q27273145 ((-)-ivabradine) (-)-ivabradine
P279 subclass of ... Q27275319 ((+/-)-ivabradine) (+/-)-ivabradine
P2868 subject has role ... Q50429907 (cardiovascular agent) cardiovascular agent
External Ids
P267ATC codeC01EB17
P231CAS Registry Number155974-00-8
P683ChEBI ID85966
P592ChEMBL IDCHEMBL471737
P661ChemSpider ID117373
P9272DeCS ID57675
P715DrugBank IDDB09083
P11198DrugCentral ID3312
P8494DSSTOX compound identifierDTXCID3028215
P3117DSSTox substance IDDTXSID2048240
P646Freebase ID/m/0d5glz
P595Guide to Pharmacology Ligand ID2357
P234InChIInChI=1S/C27H36N2O5/c1-28(17-21-11-20-14-25(33-4)26(34-5)16-22(20)21)8-6-9-29-10-7-18-12-23(31-2)24(32-3)13-19(18)15-27(29)30/h12-14,16,21H,6-11,15,17H2,1-5H3/t21-/m1/s1
P235InChIKeyACRHBAYQBXXRTO-OAQYLSRUSA-N
P665KEGG IDD07165
P7830LiverTox IDIvabradine
P10245MedlinePlus drug identifiera615027
P486MeSH descriptor IDD000077550
P672MeSH tree codeD03.633.100.079.801
P6366Microsoft Academic ID (discontinued)2779167562
P2115NDF-RT IDN0000191553
P10283OpenAlex IDC2779167562
P11199Probes And Drugs IDPD000477
P662PubChem CID132999
P3345RxNorm CUI1649480
P2877SureChEMBL ID23472
P2892UMLS CUIC0257190
P11089UniChem compound ID443398
P652UNII3H48L0LPZQ
P11143WikiProjectMed IDIvabradine

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