The impact of cellular networks on disease comorbidity

scientific article published on 7 April 2009

The impact of cellular networks on disease comorbidity is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/MSB.2009.16
P932PMC publication ID2683720
P698PubMed publication ID19357641
P5875ResearchGate publication ID24267784

P50authorAlbert-László BarabásiQ725467
Nicholas A. ChristakisQ1094336
P2093author name stringDeok-Sun Lee
Juyong Park
P2860cites workA dynamic network approach for the study of human phenotypesQ21145365
Towards a proteome-scale map of the human protein–protein interaction networkQ21735930
Scale-free networks in cell biologyQ22306161
A human protein-protein interaction network: a resource for annotating the proteomeQ24324450
The implications of human metabolic network topology for disease comorbidityQ24655183
The human disease networkQ24678240
A network biology approach to prostate cancerQ24678469
Pfam: clans, web tools and servicesQ25257103
Network biology: understanding the cell's functional organizationQ27861027
Drug-target networkQ29614447
Network motifs: theory and experimental approachesQ29615325
Reverse engineering of regulatory networks in human B cellsQ30004211
Proteomics. Integrating interactomesQ31034567
Probing genetic overlap among complex human phenotypes.Q35868799
Human disease classification in the postgenomic era: a complex systems approach to human pathobiologyQ35940380
Network properties of genes harboring inherited disease mutationsQ36670355
Networking metabolites and diseasesQ36786957
Biological impacts and context of network theoryQ36798117
A global view of pleiotropy and phenotypically derived gene function in yeastQ40510242
Amyloid and peripheral nervous system diseaseQ40754609
Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissuesQ42479713
Socio-economic status, obesity and prevalence of Type 1 and Type 2 diabetes mellitusQ45310190
Heart Disease and Dementia: A Population-based StudyQ57540223
Breast cancer after treatment for osteosarcomaQ70129346
Association studies in an era of too much information: clinical analysis of new biomarker and genetic dataQ81509480
Childhood Type 1 diabetes and parental occupation involving parental mixing and infectious contactsQ95799983
Computers and the Theory of Statistics: Thinking the UnthinkableQ100718400
P921main subjectcomorbidityQ1414874
P304page(s)262
P577publication date2009-04-07
P1433published inMolecular Systems BiologyQ2261043
P1476titleThe impact of cellular networks on disease comorbidity
P478volume5

Reverse relations

cites work (P2860)
Q55257457A Network-Biology Informed Computational Drug Repositioning Strategy to Target Disease Risk Trajectories and Comorbidities of Peripheral Artery Disease.
Q64274684A Novel Discovery: Holistic Efficacy at the Special Organ Level of Pungent Flavored Compounds from Pungent Traditional Chinese Medicine
Q42634026A co-module approach for elucidating drug–disease associations and revealing their molecular basis
Q38193097A conceptual review on systems biology in health and diseases: from biological networks to modern therapeutics
Q38807516A model-driven methodology for exploring complex disease comorbidities applied to autism spectrum disorder and inflammatory bowel disease
Q84073956A novel integrative network approach to understand the interplay between cardiovascular disease and other complex disorders
Q37822219Addressing the complexity of chronic obstructive pulmonary disease: from phenotypes and biomarkers to scale-free networks, systems biology, and P4 medicine
Q34778702Analysis and Prediction of Pathways in HeLa Cells by Integrating Biological Levels of Organization with Systems-Biology Approaches
Q91910092Analysis of disease comorbidity patterns in a large-scale China population
Q47314703Applications of network analysis to routinely collected health care data: a systematic review.
Q36188889Biconnectivity of the cellular metabolism: A cross-species study and its implication for human diseases
Q45847143Biological function through network topology: a survey of the human diseasome
Q38796894Biomechanisms of Comorbidity: Reviewing Integrative Analyses of Multi-omics Datasets and Electronic Health Records
Q35110311COSINE: COndition-SpecIfic sub-NEtwork identification using a global optimization method
Q33717801Cardiovascular networks: systems-based approaches to cardiovascular disease
Q33986568Combinations of newly confirmed Glioma-Associated loci link regions on chromosomes 1 and 9 to increased disease risk.
Q49469643Common Variable Immunodeficiency Non-Infectious Disease Endotypes Redefined Using Unbiased Network Clustering in Large Electronic Datasets
Q36333988Community of protein complexes impacts disease association
Q35953653Comorbidities of Psoriasis - Exploring the Links by Network Approach
Q39406922Comorbidity in the Tunisian population
Q91198982Comorbidity of asthma and hypertension may be mediated by shared genetic dysregulation and drug side effects
Q87259728Comorbidity: a multidimensional approach
Q24307380Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia
Q35751212Complex-disease networks of trait-associated single-nucleotide polymorphisms (SNPs) unveiled by information theory.
Q36396910Computational analysis of multimorbidity between asthma, eczema and rhinitis
Q28655601Data integration in the era of omics: current and future challenges
Q35917229Disease Comorbidity Network Guides the Detection of Molecular Evidence for the Link Between Colorectal Cancer and Obesity
Q84717320Disease embryo development network reveals the relationship between disease genes and embryo development genes
Q36337024Evolutionary history of human disease genes reveals phenotypic connections and comorbidity among genetic diseases
Q26828976Excess costs of comorbidities in chronic obstructive pulmonary disease: a systematic review
Q33987719Exploring and exploiting disease interactions from multi-relational gene and phenotype networks.
Q37439086Exploring the molecular basis of age-related disease comorbidities using a multi-omics graphical model
Q35689793Finding directionality and gene-disease predictions in disease associations
Q38479519Finding disease similarity based on implicit semantic similarity
Q64929055Focus on the emerging new fields of Network Physiology and Network Medicine.
Q41770491Formal concept analysis of disease similarity
Q31160925From comorbidities of chronic obstructive pulmonary disease to identification of shared molecular mechanisms by data integration
Q47136082Functional diversity of topological modules in human protein-protein interaction networks.
Q51398877GPEC: A Cytoscape plug-in for random walk-based gene prioritization and biomedical evidence collection
Q50718927Gene coexpression as Hebbian learning in prokaryotic genomes
Q41108481Genetic and functional characterization of disease associations explains comorbidity
Q28478625Genetic co-occurrence network across sequenced microbes
Q35559086Genetic similarity between cancers and comorbid Mendelian diseases identifies candidate driver genes
Q38791078Genomic insights into ayurvedic and western approaches to personalized medicine
Q28486526Global analysis of the human pathophenotypic similarity gene network merges disease module components
Q90164234High-risk multimorbidity patterns on the road to cardiovascular mortality
Q35775025How to build personalized multi-omics comorbidity profiles
Q38065572Human diseases through the lens of network biology
Q42668669Human symptoms-disease network
Q37519334Identification of disease comorbidity through hidden molecular mechanisms
Q41886030Identification of human disease genes from interactome network using graphlet interaction
Q40050351Impact of Comorbidity on Fatality Rate of Patients with Middle East Respiratory Syndrome.
Q34979129Insights from systems pharmacology into cardiovascular drug discovery and therapy
Q37247744Integrative Toxicoproteomics Implicates Impaired Mitochondrial Glutathione Import as an Off-Target Effect of Troglitazone
Q35078279Integrative network analysis unveils convergent molecular pathways in Parkinson's disease and diabetes
Q29615773Interactome networks and human disease
Q37345367Interactome-transcriptome analysis discovers signatures complementary to GWAS Loci of Type 2 Diabetes
Q96171869Interpreting molecular similarity between patients as a determinant of disease comorbidity relationships
Q37773558It's the machine that matters: Predicting gene function and phenotype from protein networks
Q28543366Knowledge retrieval from PubMed abstracts and electronic medical records with the Multiple Sclerosis Ontology
Q26801048Knowledge-based analysis of genetic associations of rheumatoid arthritis to inform studies searching for pleiotropic genes: a literature review and network analysis
Q34253535LDGIdb: a database of gene interactions inferred from long-range strong linkage disequilibrium between pairs of SNPs
Q37205132Large numbers of genetic variants considered to be pathogenic are common in asymptomatic individuals
Q60927110Large-scale mining disease comorbidity relationships from post-market drug adverse events surveillance data
Q24570119MalaCards: an integrated compendium for diseases and their annotation
Q55116101Mapping biological process relationships and disease perturbations within a pathway network.
Q92258448Mechanism-based disease similarity
Q34434844Mining cancer-specific disease comorbidities from a large observational health database
Q27927409Mining electronic health records: towards better research applications and clinical care
Q35497573Modeling of pathological traits in Alzheimer's disease based on systemic extracellular signaling proteome.
Q47252526Neighbor-favoring weight reinforcement to improve random walk-based disease gene prioritization
Q35753618Network Modules of the Cross-Species Genotype-Phenotype Map Reflect the Clinical Severity of Human Diseases
Q28392031Network analysis of unstructured EHR data for clinical research
Q29091067Network biology concepts in complex disease comorbidities
Q21146673Network medicine analysis of COPD multimorbidities
Q29547462Network medicine: a network-based approach to human disease
Q33595196Network properties of human disease genes with pleiotropic effects
Q37195763Network-based SNP meta-analysis identifies joint and disjoint genetic features across common human diseases
Q21284301Network-based analysis of comorbidities risk during an infection: SARS and HIV case studies
Q44745615Network-based analysis of diagnosis progression patterns using claims data
Q46895478Network-based analysis of genotype-phenotype correlations between different inheritance modes
Q38089597Network-based drug repositioning
Q60923535Novel disease syndromes unveiled by integrative multiscale network analysis of diseases sharing molecular effectors and comorbidities
Q41018163Phenotypic connections in surprising places
Q34241793Predicting disease associations via biological network analysis.
Q92331743Prediction of comorbid diseases using weighted geometric embedding of human interactome
Q47133255Prediction of missing common genes for disease pairs using network based module separation on incomplete human interactome
Q58610106Prevalence of comorbidities in cases of Middle East respiratory syndrome coronavirus: a retrospective study
Q37988818Principles of phenomics in endometriosis
Q35088894Protein localization as a principal feature of the etiology and comorbidity of genetic diseases
Q33911954Protein-protein binding selectivity and network topology constrain global and local properties of interface binding networks
Q33983503Proteomic analysis shows synthetic oleanane triterpenoid binds to mTOR
Q99237814Pulmonary and Extra-Pulmonary Clinical Manifestations of COVID-19
Q42957866Putative Role of MicroRNA-Regulated Pathways in Comorbid Neurological and Cardiovascular Disorders
Q42697674Quantitative mapping of genetic similarity in human heritable diseases by shared mutations
Q27902294Quantitative modeling of dose–response and drug combination based on pathway network
Q35768656Relationships between predicted moonlighting proteins, human diseases, and comorbidities from a network perspective
Q59137074Statistical methods for constructing disease comorbidity networks from longitudinal inpatient data
Q38036241Studying protein-protein interaction networks: a systems view on diseases
Q43055273Synergy-COPD: a systems approach for understanding and managing chronic diseases
Q41968042Systematic large-scale study of the inheritance mode of Mendelian disorders provides new insight into human diseasome.
Q37232687Systems Pharmacology Dissection of the Integrated Treatment for Cardiovascular and Gastrointestinal Disorders by Traditional Chinese Medicine
Q38647215Systems biology and the future of medicine
Q64458955The Alzheimer's comorbidity phenome: mining from a large patient database and phenome-driven genetics prediction
Q44972024The effects of feedback loops on disease comorbidity in human signaling networks
Q34036307The human metabolic reconstruction Recon 1 directs hypotheses of novel human metabolic functions
Q42964767The relationship between modularity and robustness in signalling networks
Q38266033The role of protein interaction networks in systems biomedicine.
Q33796471Towards building a disease-phenotype knowledge base: extracting disease-manifestation relationship from literature.
Q31099591Towards finding the linkage between metabolic and age-related disorders using semantic gene data network analysis
Q90730661Tracing diagnosis trajectories over millions of patients reveal an unexpected risk in schizophrenia
Q33613094Unraveling human protein interaction networks underlying co-occurrences of diseases and pathological conditions
Q29126350Using Electronic Patient Records to Discover Disease Correlations and Stratify Patient Cohorts
Q34325431Viral perturbations of host networks reflect disease etiology
Q58840477What the Journal Would Like to Publish on Chronic Obstructive Pulmonary Disease
Q42720400comoR: a software for disease comorbidity risk assessment.
Q35146179dRiskKB: a large-scale disease-disease risk relationship knowledge base constructed from biomedical text.

Search more.