T. brucei RNA editing: action of the U-insertional TUTase within a U-deletion cycle.

scientific article published in March 2006

T. brucei RNA editing: action of the U-insertional TUTase within a U-deletion cycle. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1261/RNA.2243206
P932PMC publication ID1383585
P698PubMed publication ID16495238
P5875ResearchGate publication ID7282577

P50authorJorge Cruz-ReyesQ57730274
Julie A. LawQ64815016
P2093author name stringSean F O'Hearn
Barbara Sollner-Webb
Catherine E Huang
Alevtina G Zhelonkina
Vadim S Alatortsev
P2860cites workPurification of a functional enzymatic editing complex from Trypanosoma brucei mitochondriaQ42623988
Extensive editing of the cytochrome c oxidase III transcript in Trypanosoma bruceiQ43573848
Is the Trypanosoma brucei REL1 RNA ligase specific for U-deletion RNA editing, and is the REL2 RNA ligase specific for U-insertion editing?Q44441848
TbMP57 is a 3' terminal uridylyl transferase (TUTase) of the Trypanosoma brucei editosomeQ44487520
Mass spectrometric analysis of the editosome and other multiprotein complexes in Trypanosoma brucei.Q44499264
Separate insertion and deletion subcomplexes of the Trypanosoma brucei RNA editing complex.Q44612182
Generation of unexpected editing patterns in Leishmania tarentolae mitochondrial mRNAs: misediting produced by misguidingQ44999695
Addition of uridines to edited RNAs in trypanosome mitochondria occurs independently of transcriptionQ45346139
Partially edited mRNAs for cytochrome b and subunit III of cytochrome oxidase from Leishmania tarentolae mitochondria: RNA editing intermediates.Q45949285
The Leishmania kinetoplast-mitochondrion contains terminal uridylyltransferase and RNA ligase activitiesQ46756988
Trypanosome mitochondrial 3' terminal uridylyl transferase (TUTase): the key enzyme in U-insertion/deletion RNA editingQ46840499
An RNA ligase essential for RNA editing and survival of the bloodstream form of Trypanosoma bruceiQ46859677
T. brucei RNA editing: adenosine nucleotides inversely affect U-deletion and U-insertion reactions at mRNA cleavageQ47858606
Biochemical methods for analysis of kinetoplastid RNA editing.Q48008133
RNA editing: a mechanism for gRNA-specified uridylate insertion into precursor mRNA.Q54649086
Direct visualization of uridylate deletion in vitro suggests a mechanism for kinetoplastid RNA editingQ71000760
RNA Editing: Transfer of Genetic Information from gRNA to Precursor mRNA in VitroQ71653038
Inhibition of Trypanosoma brucei gene expression by RNA interference using an integratable vector with opposing T7 promotersQ73025256
Defining the editing 'reaction'Q73049585
Unexpected electrophoretic migration of RNA with different 3' termini causes a RNA sizing ambiguity that can be resolved using nuclease P1-generated sequencing laddersQ74477697
Ribonuclease activities of trypanosome RNA editing complex directed to cleave specifically at a chosen siteQ74584561
An improved capillary electrophoresis method for measuring tissue metabolites associated with cellular energy stateQ77363197
The mechanism of U insertion/deletion RNA editing in kinetoplastid mitochondriaQ24545284
A model for RNA editing in kinetoplastid mitochondria: "guide" RNA molecules transcribed from maxicircle DNA provide the edited informationQ28255689
Roles for ligases in the RNA editing complex of Trypanosoma brucei: band IV is needed for U-deletion and RNA repair.Q28348370
RNA editing: complexity and complicationsQ28610127
Physiological concentrations of purines and pyrimidinesQ29616721
A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma bruceiQ29617358
RNA editing involves indiscriminate U changes throughout precisely defined editing domainsQ33255447
Kinetoplastid RNA-editing-associated protein 1 (REAP-1): a novel editing complex protein with repetitive domains.Q33889874
Functions and mechanisms of RNA editingQ33926245
Association of two novel proteins, TbMP52 and TbMP48, with the Trypanosoma brucei RNA editing complexQ33966791
Four related proteins of the Trypanosoma brucei RNA editing complex.Q34012441
Assembly and function of the RNA editing complex in Trypanosoma brucei requires band III proteinQ34278417
Editing machines: the complexities of trypanosome RNA editingQ34574307
Isolation of a U-insertion/deletion editing complex from Leishmania tarentolae mitochondriaQ34582995
Uridine insertion/deletion RNA editing in trypanosome mitochondria: a complex businessQ35068202
A tale of two TUTasesQ35977107
Complex management: RNA editing in trypanosomesQ36030102
RNA editing in kinetoplastid protozoaQ36574222
Trypanosome U-deletional RNA editing involves guide RNA-directed endonuclease cleavage, terminal U exonuclease, and RNA ligase activitiesQ37376878
TbMP42, a protein component of the RNA editing complex in African trypanosomes, has endo-exoribonuclease activityQ38329755
Trypanosoma brucei guide RNA poly(U) tail formation is stabilized by cognate mRNA.Q39450743
Trypanosome RNA editing: simple guide RNA features enhance U deletion 100-fold.Q39457744
The two RNA ligases of the Trypanosoma brucei RNA editing complex: cloning the essential band IV gene and identifying the band V geneQ39526694
Uridylate addition and RNA ligation contribute to the specificity of kinetoplastid insertion RNA editingQ39540061
Role of uridylate-specific exoribonuclease activity in Trypanosoma brucei RNA editingQ39618738
TbMP81 is required for RNA editing in Trypanosoma bruceiQ39647029
Distinct functions of two RNA ligases in active Trypanosoma brucei RNA editing complexes.Q39674967
RNA sequence and base pairing effects on insertion editing in Trypanosoma bruceiQ39677689
Trypanosoma brucei U insertion and U deletion activities co-purify with an enzymatic editing complex but are differentially optimized.Q39724699
Trypanosoma brucei RNA editing complex: band II is structurally critical and maintains band V ligase, which is nonessentialQ39940448
In Trypanosoma brucei RNA editing, band II enables recognition specifically at each step of the U insertion cycleQ40446650
Guide RNA-directed uridine insertion RNA editing in vitroQ41078882
Native mRNA editing complexes from Trypanosoma brucei mitochondriaQ41545292
Effects of temperature shift on cell cycle, apoptosis and nucleotide pools in CHO cell batch cultuesQ41790686
Identification of novel components of Trypanosoma brucei editosomesQ41827505
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectTrypanosoma bruceiQ33244
P304page(s)476-487
P577publication date2006-03-01
P1433published inRNAQ7277164
P1476titleT. brucei RNA editing: action of the U-insertional TUTase within a U-deletion cycle
P478volume12

Reverse relations

cites work (P2860)
Q41149338Determinants for association and guide RNA-directed endonuclease cleavage by purified RNA editing complexes from Trypanosoma brucei.
Q42124628In Trypanosoma brucei RNA editing, TbMP18 (band VII) is critical for editosome integrity and for both insertional and deletional cleavages.
Q24642701Mouse let-7 miRNA populations exhibit RNA editing that is constrained in the 5'-seed/ cleavage/anchor regions and stabilize predicted mmu-let-7a:mRNA duplexes
Q33247054Taking U out, with two nucleases?
Q38569224Trypanosoma brucei RNA editing protein TbMP42 (band VI) is crucial for the endonucleolytic cleavages but not the subsequent steps of U-deletion and U-insertion.
Q43077446Trypanosoma brucei RNA editing: coupled cycles of U deletion reveal processive activity of the editing complex.
Q44577937Uridylate-specific 3' 5'-exoribonucleases involved in uridylate-deletion RNA editing in trypanosomatid mitochondria.