"ER stress(ed out)!": Paneth cells and ischemia-reperfusion injury of the small intestine

scientific article published on 18 December 2010

"ER stress(ed out)!": Paneth cells and ischemia-reperfusion injury of the small intestine is …
instance of (P31):
editorialQ871232
scholarly articleQ13442814

External links are
P356DOI10.1053/J.GASTRO.2010.12.015
P932PMC publication ID4594951
P698PubMed publication ID21172333

P50authorArthur KaserQ88612415
P2093author name stringRichard S Blumberg
Michal Tomczak
P2860cites workGenome-wide association defines more than 30 distinct susceptibility loci for Crohn's diseaseQ22251069
XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel diseaseQ22252318
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controlsQ24550675
Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestineQ24604466
Homeostasis and inflammation in the intestineQ24613509
Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interfaceQ24644721
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesisQ24656576
Hypoxia: an alarm signal during intestinal inflammationQ27691319
Signal integration in the endoplasmic reticulum unfolded protein responseQ27860577
Genome-wide association identifies multiple ulcerative colitis susceptibility lociQ27865246
Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteriaQ28204776
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glandsQ28510479
The transcription factor XBP-1 is essential for the development and survival of dendritic cellsQ28512302
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tractQ28587612
Regulation mechanisms and signaling pathways of autophagyQ29547416
The gut microbiota shapes intestinal immune responses during health and diseaseQ29547727
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cellsQ29614565
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibilityQ29614872
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1Q29614873
Inflammatory bowel diseaseQ29615500
Inflammatory bowel diseaseQ29616286
Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cellsQ29619410
Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationshipQ34899429
TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages.Q35041384
The endoplasmic reticulum stress response in immunity and autoimmunityQ37231726
Endoplasmic reticulum stress in the intestinal epithelium and inflammatory bowel diseaseQ37399734
Ischemia activates the ATF6 branch of the endoplasmic reticulum stress responseQ37447782
Enteric defensins are essential regulators of intestinal microbial ecologyQ37483232
The genetics of Crohn's diseaseQ37488205
Endoplasmic reticulum stress and intestinal inflammationQ37623437
Endoplasmic reticulum stress: implications for inflammatory bowel disease pathogenesisQ37760005
Disruption of Paneth and goblet cell homeostasis and increased endoplasmic reticulum stress in Agr2-/- miceQ41977500
B- and T-cell development both involve activity of the unfolded protein response pathway.Q51790130
Level of activation of the unfolded protein response correlates with Paneth cell apoptosis in human small intestine exposed to ischemia/reperfusion.Q53294250
The Paneth cell alpha-defensin deficiency of ileal Crohn's disease is linked to Wnt/Tcf-4Q80819683
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectreperfusion injuryQ1413991
P304page(s)393-396
P577publication date2010-12-18
P1433published inGastroenterologyQ4039279
P1476title"ER stress(ed out)!": Paneth cells and ischemia-reperfusion injury of the small intestine
P478volume140

Reverse relations

cites work (P2860)
Q38270128Animal models of ischemia-reperfusion-induced intestinal injury: progress and promise for translational research.
Q36431001Mucosal Immune System and M Cell-targeting Strategies for Oral Mucosal Vaccination
Q51069633Protective effect of glutamine on the main and adjacent organs damaged by ischemia-reperfusion in rats.
Q35085852The cell biology of the unfolded protein response.
Q27676939The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance
Q90446620Unfolded protein response (UPR) integrated signaling networks determine cell fate during hypoxia
Q37745551Upregulation of miR-665 promotes apoptosis and colitis in inflammatory bowel disease by repressing the endoplasmic reticulum stress components XBP1 and ORMDL3.

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