Effect of peptidases on the ability of exogenous and endogenous neurokinins to produce neurokinin 1 receptor internalization in the rat spinal cord

scientific article published on November 17, 2003

Effect of peptidases on the ability of exogenous and endogenous neurokinins to produce neurokinin 1 receptor internalization in the rat spinal cord is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/SJ.BJP.0705578
P953full work available at URLhttps://bpspubs.onlinelibrary.wiley.com/doi/pdfdirect/10.1038/sj.bjp.0705578
https://europepmc.org/articles/PMC1574162
https://europepmc.org/articles/PMC1574162?pdf=render
https://doi.org/10.1038/sj.bjp.0705578
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1038%2Fsj.bjp.0705578
https://bpspubs.onlinelibrary.wiley.com/doi/pdf/10.1038/sj.bjp.0705578
P932PMC publication ID1574162
P698PubMed publication ID14623771
P5875ResearchGate publication ID9003054

P2093author name stringBingbing Song
Xueren Wang
Li-Jun Lao
Juan Carlos G. Marvizon
P2860cites workInhibition of hyperalgesia by ablation of lamina I spinal neurons expressing the substance P receptorQ73763175
Nerve growth factor- and neurotrophin-3-induced changes in nociceptive threshold and the release of substance P from the rat isolated spinal cordQ73797605
Time-course of the internalization and recycling of neurokinin 1 receptors in rat dorsal horn neuronsQ74430664
Evidence for tonic activation of NK-1 receptors during the second phase of the formalin test in the RatQ78025269
Spinal substance P receptor expression and internalization in acute, short-term, and long-term inflammatory pain statesQ78166434
Altered nociception, analgesia and aggression in mice lacking the receptor for substance PQ24322842
Leucine aminopeptidase: bestatin inhibition and a model for enzyme-catalyzed peptide hydrolysisQ24563697
Receptors and antagonists for substance P and related peptidesQ28287568
CB(1) receptor antagonist SR141716A increases capsaicin-evoked release of Substance P from the adult mouse spinal cordQ28344830
Primary afferent tachykinins are required to experience moderate to intense painQ28506575
Deficits in visceral pain and hyperalgesia of mice with a disruption of the tachykinin NK1 receptor geneQ31395644
Role of central and peripheral tachykinin NK1 receptors in capsaicin-induced pain and hyperalgesia in mice.Q31889264
Novel approaches to targeting neuropeptide systemsQ34106722
Repeated systemic administration of the mixed inhibitor of enkephalin-degrading enzymes, RB101, does not induce either antinociceptive tolerance or cross-tolerance with morphineQ34295761
Inhibition of the enkephalin-metabolizing enzymes by the first systemically active mixed inhibitor prodrug RB 101 induces potent analgesic responses in mice and ratsQ34377116
Synaptic relationship between substance P and the substance P receptor: light and electron microscopic characterization of the mismatch between neuropeptides and their receptorsQ37558489
Peptidases prevent mu-opioid receptor internalization in dorsal horn neurons by endogenously released opioids.Q40263009
Tachykinin receptors in the spinal cordQ40940969
Characterization of antisera specific to NK1, NK2, and NK3 neurokinin receptors and their utilization to localize receptors in the rat gastrointestinal tract.Q41156993
Substance P release in the dorsal horn assessed by receptor internalization: NMDA receptors counteract a tonic inhibition by GABA(B) receptorsQ41610524
The dual nature of the tachykinin NK1 receptor.Q41633157
Internalization of mu-opioid receptors in rat spinal cord slicesQ41684135
Spinal opioid analgesia: how critical is the regulation of substance P signaling?Q41697764
Effect of the tachykinin NK1 receptor antagonists, RP 67580 and SR 140333, on electrically-evoked substance P release from rat spinal cordQ41790903
Involvement of enzymatic degradation in the inactivation of tachykinin neurotransmitters in neonatal rat spinal cordQ41809899
Comparison of the effects of epithelium removal and of an enkephalinase inhibitor on the neurokinin-induced contractions of guinea-pig isolated tracheaQ42848928
Presynaptic regulation of spinal cord tachykinin signaling via GABA(B) but not GABA(A) receptor activationQ43557132
Projection neurons in lamina I of rat spinal cord with the neurokinin 1 receptor are selectively innervated by substance p-containing afferents and respond to noxious stimulation.Q43999186
Amino acid-mediated EPSPs at primary afferent synapses with substantia gelatinosa neurones in the rat spinal cordQ44134973
Postsynaptic signaling via the [mu]-opioid receptor: responses of dorsal horn neurons to exogenous opioids and noxious stimulation.Q44333978
Effects of three peptidase inhibitors, amastatin, captopril and phosphoramidon, on the hydrolysis of [Met5]-enkephalin-Arg6-Phe7 and other opioid peptidesQ44348401
Relationship between capsaicin-evoked substance P release and neurokinin 1 receptor internalization in the rat spinal cord.Q44406479
Differential contribution of substance P and neurokinin A to spinal cord neurokinin-1 receptor signaling in the rat.Q45027502
Studies on the effect of SCH-34826 and thiorphan on [Met5]enkephalin levels and release in rat spinal cord.Q45934622
Inflammation increases the distribution of dorsal horn neurons that internalize the neurokinin-1 receptor in response to noxious and non-noxious stimulation.Q46304913
NMDA-receptor regulation of substance P release from primary afferent nociceptorsQ46378238
Thiorphan increases capsaicin-evoked release of substance P from slices of dorsal spinal cord of guinea pig.Q46494871
Neurokinin 1 receptor internalization in spinal cord slices induced by dorsal root stimulation is mediated by NMDA receptors.Q46662825
Effect of peptidase inhibition on the pattern of intraspinally released immunoreactive substance P detected with antibody microprobesQ47569918
Lack of physical dependence in mice after repeated systemic administration of the mixed inhibitor prodrug of enkephalin-degrading enzymes, RB101Q48407392
Aminopeptidase P from rat brain. Purification and action on bioactive peptidesQ48719143
Blind patch-clamp recordings from substantia gelatinosa neurons in adult rat spinal cord slices: pharmacological properties of synaptic currents.Q51671347
Bronchoconstrictor and hypotensive effects in relation to pharmacokinetics of tachykinins in the guinea-pig--evidence for extraneuronal cleavage of neuropeptide K to neurokinin A.Q51787780
C-fiber excitability in the cat.Q54074721
Inhibition of aminopeptidases N, A and WQ56450176
Enkephalin degradation in mouse brain studied by a new H.P.L.C. method: Further evidence for the involvement of carboxydipeptidaseQ66981908
Excitability characteristics of the A- and C-fibers in a peripheral nerveQ67435205
Is substance P released from slices of the rat spinal cord inactivated by peptidase(s) distinct from both ‘enkephalinase’ and ‘angiotensin-converting enzyme’?Q67689315
Phosphoramidon potentiates mammalian tachykinin-induced biting, licking and scratching behaviour in miceQ67689702
Release of substance P from the cat spinal cordQ69022182
Peptidase inhibitors improve recovery of substance P and calcitonin gene-related peptide release from rat spinal cord slicesQ71570083
The correlation between the distribution of the NK1 receptor and the actions of tachykinin agonists in the dorsal horn of the rat indicates that substance P does not have a functional role on substantia gelatinosa (lamina II) neuronsQ71662662
Receptor endocytosis and dendrite reshaping in spinal neurons after somatosensory stimulationQ71696623
The spinal contribution of substance P to the generation and maintenance of inflammatory hyperalgesia in the ratQ71733165
Gamma-aminobutyric acidB, but not gamma-aminobutyric acidA receptor activation, inhibits electrically evoked substance P-like immunoreactivity release from the rat spinal cord in vitroQ72094858
Long-term potentiation and long-term depression of primary afferent neurotransmission in the rat spinal cordQ72640836
Action of peptidase inhibitors on methionine5-enkephalin-arginine6-phenylalanine7 (YGGFMRF) and methionine5-enkephalin (YGGFM) metabolism and on electroacupuncture antinociceptionQ72739799
Neurochemical and cellular reorganization of the spinal cord in a murine model of bone cancer painQ73263697
Noxious cutaneous thermal stimuli induce a graded release of endogenous substance P in the spinal cord: imaging peptide action in vivoQ73507903
Low-frequency stimulation of afferent Adelta-fibers induces long-term depression at primary afferent synapses with substantia gelatinosa neurons in the ratQ73542551
Enzymatic inactivation of enkephalin neurotransmitters in the spinal cord of the neonatal ratQ73544660
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectpharmacologyQ128406
NK1 receptor antagonistsQ12744608
P304page(s)1389-1398
P577publication date2003-11-17
P1433published inBritish Journal of PharmacologyQ919631
P1476titleEffect of peptidases on the ability of exogenous and endogenous neurokinins to produce neurokinin 1 receptor internalization in the rat spinal cord
P478volume140

Reverse relations

cites work (P2860)
Q28578470Acute inflammation induces segmental, bilateral, supraspinally mediated opioid release in the rat spinal cord, as measured by mu-opioid receptor internalization
Q33803774Cannabinoid CB1 receptor facilitation of substance P release in the rat spinal cord, measured as neurokinin 1 receptor internalization
Q36155156Comparing analgesia and mu-opioid receptor internalization produced by intrathecal enkephalin: requirement for peptidase inhibition
Q35186509Inflammation enhances Y1 receptor signaling, neuropeptide Y-mediated inhibition of hyperalgesia, and substance P release from primary afferent neurons.
Q37998313Inhibiting the breakdown of endogenous opioids and cannabinoids to alleviate pain
Q44348612Inhibition by spinal mu- and delta-opioid agonists of afferent-evoked substance P release.
Q44349884Mechanisms of μ-opioid receptor inhibition of NMDA receptor-induced substance P release in the rat spinal cord
Q34536694N-methyl-D-aspartate receptors and large conductance calcium-sensitive potassium channels inhibit the release of opioid peptides that induce mu-opioid receptor internalization in the rat spinal cord
Q39576351NMDA receptors in primary afferents require phosphorylation by Src family kinases to induce substance P release in the rat spinal cord
Q34142913Src family kinases mediate the inhibition of substance P release in the rat spinal cord by μ-opioid receptors and GABA(B) receptors, but not α2 adrenergic receptors
Q41924456Substance P release and neurokinin 1 receptor activation in the rat spinal cord increase with the firing frequency of C-fibers.
Q26745801The involvement of TRPV1 in emesis and anti-emesis
Q37721910μ-Opioid receptor inhibition of substance P release from primary afferents disappears in neuropathic pain but not inflammatory pain

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