Ischaemic postconditioning protects against reperfusion injury via the SAFE pathway

scientific article published on 7 August 2009

Ischaemic postconditioning protects against reperfusion injury via the SAFE pathway is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/CVR/CVP274
P698PubMed publication ID19666677
P5875ResearchGate publication ID26728555

P50authorLionel OpieQ61046058
P2093author name stringSarin Somers
Sandrine Lecour
Lydia Lacerda
P2860cites workTumor necrosis factor-alpha and its receptors 1 and 2: Yin and Yang in myocardial infarction?Q51789753
Current trends and controversies in ischemia-reperfusion research--meeting report of the Hatter Institute 3rd International Workshop on Cardioprotection.Q53302031
An RNA-binding protein alphaCP-1 is involved in the STAT3-mediated suppression of NF-kappaB transcriptional activity.Q53563553
Inhibition of myocardial injury by ischemic postconditioning during reperfusion: comparison with ischemic preconditioningQ28187266
Myocardial reperfusion: a double-edged sword?Q28236054
Dual activation of STAT-3 and Akt is required during the trigger phase of ischaemic preconditioningQ28771386
Myocardial reperfusion injury.Q34687124
Activation of the protective Survivor Activating Factor Enhancement (SAFE) pathway against reperfusion injury: Does it go beyond the RISK pathway?Q34974091
Inflammatory mediators and the failing heart: past, present, and the foreseeable futureQ35011415
G protein mediated signaling pathways in lysophospholipid induced cell proliferation and survivalQ35839028
Signal transducer and activator of transcription 3 is involved in the cardioprotective signalling pathway activated by insulin therapy at reperfusionQ36099739
Combined sphingosine, S1P and ischemic postconditioning rescue the heart after protracted ischemiaQ36109455
A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth programQ36187399
Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarctionQ36977754
Role of glycogen synthase kinase-3beta in cardioprotectionQ37303154
Aging mouse hearts are refractory to infarct size reduction with post-conditioningQ39321486
Insights from knock-out models concerning postischemic release of TNFalpha from isolated mouse heartsQ42504019
Ischemic postconditioning during reperfusion activates Akt and ERK without protecting against lethal myocardial ischemia-reperfusion injury in pigsQ42670257
Identification of a novel role for sphingolipid signaling in TNF alpha and ischemic preconditioning mediated cardioprotectionQ44022447
Classic ischemic but not pharmacologic preconditioning is abrogated following genetic ablation of the TNFalpha geneQ44088296
Postconditioning: a form of "modified reperfusion" protects the myocardium by activating the phosphatidylinositol 3-kinase-Akt pathwayQ44970377
Sphingosine kinase activation mediates ischemic preconditioning in murine heartQ45081177
Free radicals trigger TNF alpha-induced cardioprotectionQ45203259
Native and reconstituted HDL activate Stat3 in ventricular cardiomyocytes via ERK1/2: role of sphingosine-1-phosphateQ46158490
TNFalpha is required to confer protection in an in vivo model of classical ischaemic preconditioningQ46224947
Ischemic postconditioning in pigs: no causal role for RISK activation.Q46225223
Effect of cyclosporine on reperfusion injury in acute myocardial infarctionQ46453592
Glycogen synthase kinase-3 inactivation is not required for ischemic preconditioning or postconditioning in the mouseQ46516043
Ischaemic postconditioning protects isolated mouse hearts against ischaemia/reperfusion injury via sphingosine kinase isoform-1 activationQ46707477
Postconditioning the human heartQ46722557
Pharmacological preconditioning with tumor necrosis factor-alpha activates signal transducer and activator of transcription-3 at reperfusion without involving classic prosurvival kinases (Akt and extracellular signal-regulated kinase).Q46847925
Multiple protective pathways against reperfusion injury: a SAFE path without Aktion?Q51752588
P433issue2
P921main subjectreperfusion injuryQ1413991
P304page(s)201-208
P577publication date2009-08-07
P1433published inCardiovascular ResearchQ4642329
P1476titleIschaemic postconditioning protects against reperfusion injury via the SAFE pathway
P478volume84

Reverse relations

cites work (P2860)
Q47237585A systematic review and meta-analysis evaluating ischemic conditioning during percutaneous coronary intervention
Q38125624Adiponectin: mechanisms and new therapeutic approaches for restoring diabetic heart sensitivity to ischemic post-conditioning
Q90642839Adropin reduces hypoxia/reoxygenation-induced myocardial injury via the reperfusion injury salvage kinase pathway
Q54920287An overview of protective strategies against ischemia/reperfusion injury: The role of hyperbaric oxygen preconditioning.
Q35879483Cardiac and hepatic role of r-AtHSP70: basal effects and protection against ischemic and sepsis conditions
Q64115717Cardiac inflammatory CD11b/c cells exert a protective role in hypertrophied cardiomyocyte by promoting TNFR- and Orai3- dependent signaling
Q37160528Cardiac vulnerability to ischemia/reperfusion injury drastically increases in late pregnancy
Q90102755Cardiomyocyte damage control in heart failure and the role of the sarcolemma
Q42318959Cardiomyocyte mitochondria as targets of humoral factors released by remote ischemic preconditioning
Q49046559Cardioprotection by ischemic postconditioning is abolished in depressed rats: role of Akt and signal transducer and activator of transcription-3
Q39284051Cardioprotection with postconditioning: loss of efficacy in murine models of type-2 and type-1 diabetes
Q38055280Cardioprotection: chances and challenges of its translation to the clinic
Q38855645Caveolin-1/-3: therapeutic targets for myocardial ischemia/reperfusion injury.
Q36320864Chronic intermittent hypoxia exposure improves left ventricular contractility in transgenic mice with heart failure
Q37427908Controlled Reperfusion Strategies Improve Cardiac Hemodynamic Recovery after Warm Global Ischemia in an Isolated, Working Rat Heart Model of Donation after Circulatory Death (DCD).
Q34583556Critical role of the STAT3 pathway in the cardioprotective efficacy of zoniporide in a model of myocardial preservation – the rat isolated working heart
Q28396645Cytoprotection by the modulation of mitochondrial electron transport chain: the emerging role of mitochondrial STAT3
Q34181839Deciphering STAT3 Signaling in the Heart: Plasticity and Vascular Inflammation
Q47968505Diazoxide postconditioning induces mitochondrial protein S-nitrosylation and a redox-sensitive mitochondrial phosphorylation/translocation of RISK elements: no role for SAFE.
Q36895459Differential STAT3 signaling in the heart: Impact of concurrent signals and oxidative stress
Q54394090Effects of ischaemic post-conditioning on the early and late testicular damage after experimental testis ischaemia-reperfusion.
Q37871976Efficacy of cardioprotective 'conditioning' strategies in aging and diabetic cohorts: the co-morbidity conundrum
Q35902467Endogenous cardioprotection by ischaemic postconditioning and remote conditioning
Q48118483Enhanced Cardiac S100A1 Expression Improves Recovery from Global Ischemia-Reperfusion Injury
Q44796686Essential role of EGFR in cardioprotection and signaling responses to A1 adenosine receptors and ischemic preconditioning
Q42861824Ethanolamine is a novel STAT-3 dependent cardioprotective agent
Q38803858Evidence of necroptosis in hearts subjected to various forms of ischemic insults.
Q54463866Glimepiride treatment facilitates ischemic preconditioning in the diabetic heart.
Q39323549Glucagon-like peptide-1 (GLP-1) mediates cardioprotection by remote ischaemic conditioning
Q38255143Hexokinases and cardioprotection
Q36895483High density lipoprotein/sphingosine-1-phosphate-induced cardioprotection: Role of STAT3 as part of the SAFE pathway
Q46359823High-Density Lipoprotein Regulation of Mitochondrial Function
Q38827052High-density lipoprotein, mitochondrial dysfunction and cell survival mechanisms
Q42052171Hydrogen sulfide post-conditioning preserves interfibrillar mitochondria of rat heart during ischemia reperfusion injury
Q36355264Influence of tumour necrosis factor alpha on the outcome of ischaemic postconditioning in the presence of obesity and diabetes
Q34300508Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion
Q54168695Interleukin-27, a novel cytokine induced by ischemia-reperfusion injury in rat hearts, mediates cardioprotective effects via the gp130/STAT3 pathway.
Q46273075Interplay between SAFE and RISK pathways in sphingosine-1-phosphate-induced cardioprotection
Q46031696Intralipid protects the heart in late pregnancy against ischemia/reperfusion injury via Caveolin2/STAT3/GSK-3β pathway.
Q36196031Involvement of Glycogen Synthase Kinase-3β and Oxidation Status in the Loss of Cardioprotection by Postconditioning in Chronic Diabetic Male Rats.
Q34166155Is red wine a SAFE sip away from cardioprotection? Mechanisms involved in resveratrol- and melatonin-induced cardioprotection
Q33605260Is there a role for ischaemic conditioning in cardiac surgery?
Q28072918Ischaemic conditioning and targeting reperfusion injury: a 30 year voyage of discovery
Q38192849Ischaemic conditioning strategies for the nephrologist: a promise lost in translation?
Q34457775Ischemic conditioning: the challenge of protecting the diabetic heart
Q90581463Ischemic postconditioning reduces infarct size and microvascular obstruction zone in acute ST-elevation myocardial infarction - a randomized study
Q41394648JAK-STAT: Getting to the heart of the matter
Q37234246Kinetics and Signal Activation Properties of Circulating Factor(s) From Healthy Volunteers Undergoing Remote Ischemic Pre-Conditioning
Q34636288Long-term impact of postconditioning on infarct size and left ventricular ejection fraction in patients with ST-elevation myocardial infarction
Q38382564Long-term outcome following remote ischemic postconditioning during percutaneous coronary interventions-the RIP-PCI trial long-term follow-up
Q35750878Long-term, regular remote ischemic preconditioning improves endothelial function in patients with coronary heart disease
Q35037331MG53 participates in ischaemic postconditioning through the RISK signalling pathway
Q37225580MG53 permeates through blood-brain barrier to protect ischemic brain injury
Q89551733Mechanical Postconditioning Promotes Glucose Metabolism and AMPK Activity in Parallel with Improved Post-Ischemic Recovery in an Isolated Rat Heart Model of Donation after Circulatory Death
Q38391278Mitochondria as key targets of cardioprotection in cardiac ischemic disease: role of thyroid hormone triiodothyronine
Q38120093Molecular mechanisms of ischemic conditioning: translation into patient outcomes
Q36908289Myocardial AKT: the omnipresent nexus
Q34659969Myocardial post-conditioning with Danshen-Gegen decoction protects against isoproterenol-induced myocardial injury via a PKCε/mKATP-mediated pathway in rats
Q36405244N-Acetylcysteine Restores Sevoflurane Postconditioning Cardioprotection against Myocardial Ischemia-Reperfusion Injury in Diabetic Rats.
Q98224540Novel Therapeutic Targets for Hypoxia-Related Cardiovascular Diseases: The Role of HIF-1
Q38046547Oxidative stress and myocardial injury in the diabetic heart
Q39238269Parathyroid Hormone-Related Peptide: A Novel Endocrine Cardioprotective "Conditioning Mimetic".
Q34206337Perconditioning and postconditioning: current knowledge, knowledge gaps, barriers to adoption, and future directions
Q35556989Pharmacological postconditioning with lactic acid and hydrogen rich saline alleviates myocardial reperfusion injury in rats
Q52578576Phoenixin: uncovering its receptor, signaling and functions.
Q37499879Phosphomimetic modulation of eNOS improves myocardial reperfusion and mimics cardiac postconditioning in mice.
Q84040560Post-ischemic early acidosis in cardiac postconditioning modifies the activity of antioxidant enzymes, reduces nitration, and favors protein S-nitrosylation
Q37744271Postconditioning and protection from reperfusion injury: where do we stand? Position paper from the Working Group of Cellular Biology of the Heart of the European Society of Cardiology
Q85122796Postconditioning in acute myocardial infarction: Primary angioplasty revisited?
Q35426709Postconditioning inhibits myocardial apoptosis during prolonged reperfusion via a JAK2-STAT3-Bcl-2 pathway
Q27021021Postconditioning signalling in the heart: mechanisms and translatability
Q42039904Potential humoral mediators of remote ischemic preconditioning in patients undergoing surgical coronary revascularization
Q34215871RISK and SAFE signaling pathway involvement in apolipoprotein A-I-induced cardioprotection
Q38125147Regulation of cellular gas exchange, oxygen sensing, and metabolic control
Q41686281Remote Ischemic Conditioning by Effluent Collected from a Novel Isolated Hindlimb Model Reduces Infarct Size in an Isolated Heart Model
Q96348665Remote ischemic conditioning in active ulcerative colitis: An explorative randomized clinical trial
Q26830560Role of the MPTP in conditioning the heart - translatability and mechanism
Q40434074Role of toll-like receptor 4 in melatonin-induced cardioprotection
Q38256778Roles of obese-insulin resistance and anti-diabetic drugs on the heart with ischemia-reperfusion injury
Q36895468STAT transcription in the ischemic heart
Q54390219STAT3α interacts with nuclear GSK3beta and cytoplasmic RISK pathway and stabilizes rhythm in the anoxic-reoxygenated embryonic heart.
Q41823037Short-interval postconditioning protects the bowel against ischaemia-reperfusion injury in rats
Q38247701Signalling pathways and mechanisms of protection in pre- and postconditioning: historical perspective and lessons for the future
Q48961004Silencing cardiomyocyte TLR4 reduces injury following hypoxia
Q34584267Soluble TNF receptors are associated with infarct size and ventricular dysfunction in ST-elevation myocardial infarction
Q27001065Sphingosine kinase and sphingosine 1-phosphate in the heart: a decade of progress
Q38202410Stromal derived factor 1α: a chemokine that delivers a two-pronged defence of the myocardium.
Q55088026Study of respiratory chain dysfunction in heart disease.
Q34458657Sustained Ligand-Activated Preconditioning via δ-Opioid Receptors
Q50130549TNF receptor-activated factor 2 mediates cardiac protection through noncanonical NF-κB signaling
Q41239818TNFR2 Stimulation Promotes Mitochondrial Fusion via Stat3- and NF-kB-Dependent Activation of OPA1 Expression
Q37767172TNFα in myocardial ischemia/reperfusion, remodeling and heart failure
Q36148170TNFα protects cardiac mitochondria independently of its cell surface receptors
Q39046345Tackling myocardial ischemic injury: the signal transducer and activator of transcription 3 (STAT3) at a good site
Q38010782Targeting reperfusion injury in acute myocardial infarction: a review of reperfusion injury pharmacotherapy
Q51124858The RIPOST-MI study, assessing remote ischemic perconditioning alone or in combination with local ischemic postconditioning in ST-segment elevation myocardial infarction.
Q47100578The RISK pathway and beyond.
Q99615238The Rationale of Neprilysin Inhibition in Prevention of Myocardial Ischemia-Reperfusion Injury during ST-Elevation Myocardial Infarction
Q48238697The SAFE pathway for cardioprotection: is this a promising target?
Q47255415The antiarrhythmic dipeptide ZP1609 (danegaptide) when given at reperfusion reduces myocardial infarct size in pigs
Q36072077The immunosuppressant FTY720 prolongs survival in a mouse model of diet-induced coronary atherosclerosis and myocardial infarction.
Q38191219The impact of ischemia-reperfusion injury on the effectiveness of primary angioplasty in ST-segment elevation myocardial infarction
Q38274962The mitochondrial permeability transition pore and its role in myocardial ischemia reperfusion injury.
Q38318626Trans-system mechanisms against ischemic myocardial injury
Q38075417Translating cardioprotection for patient benefit: position paper from the Working Group of Cellular Biology of the Heart of the European Society of Cardiology.
Q55296393Transplantation of Hearts Donated after Circulatory Death.
Q38542449Treatment of Myocardial Ischemia/Reperfusion Injury by Ischemic and Pharmacological Postconditioning
Q38790211Understanding STAT3 signaling in cardiac ischemia.
Q37838085When are pro-inflammatory cytokines SAFE in heart failure?