scholarly article | Q13442814 |
P50 | author | Kenneth M. Scaglione | Q42386382 |
Larry Sklar | Q59753606 | ||
Tione Buranda | Q124727190 | ||
P2093 | author name string | Lingxiao Zhang | |
Dorota Skowyra | |||
Andrew E Deffenbaugh | |||
Johnnie M Moore | |||
P2860 | cites work | SGT1 encodes an essential component of the yeast kinetochore assembly pathway and a novel subunit of the SCF ubiquitin ligase complex | Q22003770 |
ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity | Q22009487 | ||
Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex | Q24290565 | ||
The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction | Q24292709 | ||
Conformational flexibility underlies ubiquitin ligation mediated by the WWP1 HECT domain E3 ligase | Q24292829 | ||
Protein-protein interactions within an E2-RING finger complex. Implications for ubiquitin-dependent DNA damage repair | Q42691419 | ||
Detection of epitope-tagged proteins in flow cytometry: fluorescence resonance energy transfer-based assays on beads with femtomole resolution | Q43793868 | ||
Context of multiubiquitin chain attachment influences the rate of Sic1 degradation | Q44487504 | ||
Construct for high-level expression and low misincorporation of lysine for arginine during expression of pET-encoded eukaryotic proteins in Escherichia coli | Q73206776 | ||
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex | Q24294734 | ||
Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase | Q24306203 | ||
The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2 | Q24597101 | ||
Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34 | Q24602536 | ||
Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade | Q27620360 | ||
Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases | Q27626747 | ||
Structure of a conjugating enzyme-ubiquitin thiolester intermediate reveals a novel role for the ubiquitin tail | Q27635260 | ||
Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase | Q27640370 | ||
Structure of tetraubiquitin shows how multiubiquitin chains can be formed | Q27730945 | ||
Mechanisms underlying ubiquitination | Q27860656 | ||
Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex | Q27933259 | ||
F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex | Q27934075 | ||
SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box | Q27936367 | ||
The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain | Q27937065 | ||
A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p | Q27939049 | ||
The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae | Q27939221 | ||
Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1. | Q27940059 | ||
Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast | Q27940196 | ||
The Ubc3 (Cdc34) ubiquitin-conjugating enzyme is ubiquitinated and phosphorylated in vivo | Q27940309 | ||
RING finger proteins: mediators of ubiquitin ligase activity | Q28139717 | ||
Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha | Q28143121 | ||
The Nedd8-conjugated ROC1-CUL1 core ubiquitin ligase utilizes Nedd8 charged surface residues for efficient polyubiquitin chain assembly catalyzed by Cdc34 | Q28201996 | ||
Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication | Q28209282 | ||
Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase | Q28506124 | ||
SCF and Cullin/Ring H2-based ubiquitin ligases | Q29547637 | ||
Phosphorylation of Sic1p by G1 Cdk required for its degradation and entry into S phase | Q29618007 | ||
A chimeric ubiquitin conjugating enzyme that combines the cell cycle properties of CDC34 (UBC3) and the DNA repair properties of RAD6 (UBC2): implications for the structure, function and evolution of the E2s | Q33938223 | ||
Creation of a pluripotent ubiquitin-conjugating enzyme | Q34012276 | ||
An essential domain within Cdc34p is required for binding to a complex containing Cdc4p and Cdc53p in Saccharomyces cerevisiae | Q34455840 | ||
Structural basis of ubiquitylation. | Q35035278 | ||
Cdc34 self-association is facilitated by ubiquitin thiolester formation and is required for its catalytic activity | Q35161788 | ||
Multiple lysine mutations in the C-terminal domain of p53 interfere with MDM2-dependent protein degradation and ubiquitination | Q39540284 | ||
NEDD8 recruits E2-ubiquitin to SCF E3 ligase. | Q39731260 | ||
SIC1 is ubiquitinated in vitro by a pathway that requires CDC4, CDC34, and cyclin/CDK activities | Q40243716 | ||
Identification of a portable determinant of cell cycle function within the carboxyl-terminal domain of the yeast CDC34 (UBC3) ubiquitin conjugating (E2) enzyme | Q41531902 | ||
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | protein ubiquitination | Q3547638 |
P304 | page(s) | 611-622 | |
P577 | publication date | 2003-09-01 | |
P1433 | published in | Cell | Q655814 |
P1476 | title | Release of ubiquitin-charged Cdc34-S - Ub from the RING domain is essential for ubiquitination of the SCF(Cdc4)-bound substrate Sic1. | |
P478 | volume | 114 |
Q27930959 | ATP hydrolysis-dependent disassembly of the 26S proteasome is part of the catalytic cycle |
Q28478315 | An acidic loop and cognate phosphorylation sites define a molecular switch that modulates ubiquitin charging activity in Cdc34-like enzymes |
Q34346819 | Biochemical and structural characterization of the ubiquitin-conjugating enzyme UBE2W reveals the formation of a noncovalent homodimer |
Q40322697 | CAND1-mediated substrate adaptor recycling is required for efficient repression of Nrf2 by Keap1. |
Q35541468 | COP9 signalosome: a multifunctional regulator of SCF and other cullin-based ubiquitin ligases |
Q47845473 | CSN facilitates Cullin-RING ubiquitin ligase function by counteracting autocatalytic adapter instability |
Q40140650 | Cdc34 C-terminal tail phosphorylation regulates Skp1/cullin/F-box (SCF)-mediated ubiquitination and cell cycle progression. |
Q79108304 | Cdc34: cycling on and off the SCF |
Q40020862 | Coordinated activation of the nuclear ubiquitin ligase Cul3-SPOP by the generation of phosphatidylinositol 5-phosphate. |
Q35740993 | Cullin-based ubiquitin ligases: Cul3-BTB complexes join the family. |
Q48271368 | DNA Damage-Induced Foci of E2 Ubiquitin-Conjugating Enzyme are Detectable upon Co-transfection with an Interacting E3 Ubiquitin Ligase. |
Q35786131 | DNA damage-induced activation of CUL4B targets HUWE1 for proteasomal degradation |
Q78756247 | Dynamic release of Cdc34 from SCF. the hand that rocks the cradle |
Q28270616 | E2 conjugating enzymes must disengage from their E1 enzymes before E3-dependent ubiquitin and ubiquitin-like transfer |
Q39936932 | E3 ligases determine ubiquitination site and conjugate type by enforcing specificity on E2 enzymes |
Q42083948 | Entropy-driven mechanism of an E3 ligase |
Q28131707 | Function and regulation of cullin-RING ubiquitin ligases |
Q27316805 | Functional diversity and structural disorder in the human ubiquitination pathway |
Q35681247 | Getting into position: the catalytic mechanisms of protein ubiquitylation |
Q79968436 | HIF-1alpha and EPAS ubiquitination mediated by the VHL tumour suppressor involves flexibility in the ubiquitination mechanism, similar to other RING E3 ligases |
Q42067617 | Human Cdc34 employs distinct sites to coordinate attachment of ubiquitin to a substrate and assembly of polyubiquitin chains |
Q28298559 | Identification of the preferential ubiquitination site and ubiquitin-dependent degradation signal of Rpn4 |
Q46086721 | In vitro reconstitution of SCF substrate ubiquitination with purified proteins |
Q42493490 | Mechanisms of mono- and poly-ubiquitination: Ubiquitination specificity depends on compatibility between the E2 catalytic core and amino acid residues proximal to the lysine. |
Q27653834 | Mechanistic insights into active site-associated polyubiquitination by the ubiquitin-conjugating enzyme Ube2g2 |
Q37018242 | Molecular and structural insight into lysine selection on substrate and ubiquitin lysine 48 by the ubiquitin-conjugating enzyme Cdc34 |
Q40337840 | Molecular basis for lysine specificity in the yeast ubiquitin-conjugating enzyme Cdc34. |
Q24563960 | N-Terminal ubiquitination of extracellular signal-regulated kinase 3 and p21 directs their degradation by the proteasome |
Q26865081 | Protein monoubiquitination and polyubiquitination generate structural diversity to control distinct biological processes |
Q37893657 | Proteolysis in illness-associated skeletal muscle atrophy: from pathways to networks |
Q44945693 | Proteolysis-independent regulation of the transcription factor Met4 by a single Lys 48-linked ubiquitin chain. |
Q24530602 | Proximity-induced activation of human Cdc34 through heterologous dimerization |
Q36882870 | RNF168 forms a functional complex with RAD6 during the DNA damage response |
Q27931730 | Rpn4 is a physiological substrate of the Ubr2 ubiquitin ligase |
Q35950158 | SCF E3-mediated autoubiquitination negatively regulates activity of Cdc34 E2 but plays a nonessential role in the catalytic cycle in vitro and in vivo |
Q27678117 | Selective Recruitment of an E2 Ubiquitin Complex by an E3 Ubiquitin Ligase |
Q38346254 | Stability of homologue of Slimb F-box protein is regulated by availability of its substrate |
Q27936146 | The NEF4 complex regulates Rad4 levels and utilizes Snf2/Swi2-related ATPase activity for nucleotide excision repair |
Q28279993 | The SCF ubiquitin ligase: insights into a molecular machine |
Q29618398 | The anaphase promoting complex/cyclosome: a machine designed to destroy |
Q37681979 | The enzymes in ubiquitin-like post-translational modifications |
Q42720645 | The loop-less tmCdc34 E2 mutant defective in polyubiquitination in vitro and in vivo supports yeast growth in a manner dependent on Ubp14 and Cka2. |
Q24299024 | Topors functions as an E3 ubiquitin ligase with specific E2 enzymes and ubiquitinates p53 |
Q24653688 | Ubc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradation |
Q24676092 | Ubiquitin charging of human class III ubiquitin-conjugating enzymes triggers their nuclear import |
Q37637735 | Ufd2p synthesizes branched ubiquitin chains to promote the degradation of substrates modified with atypical chains |
Q42196272 | Unique role for the UbL-UbA protein Ddi1 in turnover of SCFUfo1 complexes |
Q44852706 | Vpu-mediated degradation of CD4 reconstituted in yeast reveals mechanistic differences to cellular ER-associated protein degradation |
Q34545649 | gp78 elongates of polyubiquitin chains from the distal end through the cooperation of its G2BR and CUE domains |
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