Release of ubiquitin-charged Cdc34-S - Ub from the RING domain is essential for ubiquitination of the SCF(Cdc4)-bound substrate Sic1.

scientific article published in September 2003

Release of ubiquitin-charged Cdc34-S - Ub from the RING domain is essential for ubiquitination of the SCF(Cdc4)-bound substrate Sic1. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0092-8674(03)00641-X
P698PubMed publication ID13678584
P5875ResearchGate publication ID9887275

P50authorKenneth M. ScaglioneQ42386382
Larry SklarQ59753606
Tione BurandaQ124727190
P2093author name stringLingxiao Zhang
Dorota Skowyra
Andrew E Deffenbaugh
Johnnie M Moore
P2860cites workSGT1 encodes an essential component of the yeast kinetochore assembly pathway and a novel subunit of the SCF ubiquitin ligase complexQ22003770
ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activityQ22009487
Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complexQ24290565
The ubiquitin-proteasome proteolytic pathway: destruction for the sake of constructionQ24292709
Conformational flexibility underlies ubiquitin ligation mediated by the WWP1 HECT domain E3 ligaseQ24292829
Protein-protein interactions within an E2-RING finger complex. Implications for ubiquitin-dependent DNA damage repairQ42691419
Detection of epitope-tagged proteins in flow cytometry: fluorescence resonance energy transfer-based assays on beads with femtomole resolutionQ43793868
Context of multiubiquitin chain attachment influences the rate of Sic1 degradationQ44487504
Construct for high-level expression and low misincorporation of lysine for arginine during expression of pET-encoded eukaryotic proteins in Escherichia coliQ73206776
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complexQ24294734
Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligaseQ24306203
The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2Q24597101
Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34Q24602536
Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascadeQ27620360
Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligasesQ27626747
Structure of a conjugating enzyme-ubiquitin thiolester intermediate reveals a novel role for the ubiquitin tailQ27635260
Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligaseQ27640370
Structure of tetraubiquitin shows how multiubiquitin chains can be formedQ27730945
Mechanisms underlying ubiquitinationQ27860656
Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complexQ27933259
F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complexQ27934075
SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-boxQ27936367
The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chainQ27937065
A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1pQ27939049
The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiaeQ27939221
Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1.Q27940059
Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeastQ27940196
The Ubc3 (Cdc34) ubiquitin-conjugating enzyme is ubiquitinated and phosphorylated in vivoQ27940309
RING finger proteins: mediators of ubiquitin ligase activityQ28139717
Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alphaQ28143121
The Nedd8-conjugated ROC1-CUL1 core ubiquitin ligase utilizes Nedd8 charged surface residues for efficient polyubiquitin chain assembly catalyzed by Cdc34Q28201996
Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replicationQ28209282
Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligaseQ28506124
SCF and Cullin/Ring H2-based ubiquitin ligasesQ29547637
Phosphorylation of Sic1p by G1 Cdk required for its degradation and entry into S phaseQ29618007
A chimeric ubiquitin conjugating enzyme that combines the cell cycle properties of CDC34 (UBC3) and the DNA repair properties of RAD6 (UBC2): implications for the structure, function and evolution of the E2sQ33938223
Creation of a pluripotent ubiquitin-conjugating enzymeQ34012276
An essential domain within Cdc34p is required for binding to a complex containing Cdc4p and Cdc53p in Saccharomyces cerevisiaeQ34455840
Structural basis of ubiquitylation.Q35035278
Cdc34 self-association is facilitated by ubiquitin thiolester formation and is required for its catalytic activityQ35161788
Multiple lysine mutations in the C-terminal domain of p53 interfere with MDM2-dependent protein degradation and ubiquitinationQ39540284
NEDD8 recruits E2-ubiquitin to SCF E3 ligase.Q39731260
SIC1 is ubiquitinated in vitro by a pathway that requires CDC4, CDC34, and cyclin/CDK activitiesQ40243716
Identification of a portable determinant of cell cycle function within the carboxyl-terminal domain of the yeast CDC34 (UBC3) ubiquitin conjugating (E2) enzymeQ41531902
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectprotein ubiquitinationQ3547638
P304page(s)611-622
P577publication date2003-09-01
P1433published inCellQ655814
P1476titleRelease of ubiquitin-charged Cdc34-S - Ub from the RING domain is essential for ubiquitination of the SCF(Cdc4)-bound substrate Sic1.
P478volume114

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