β-Ketoacyl-Acyl Carrier Protein Synthase III (FabH) Is Essential for Bacterial Fatty Acid Synthesis

scientific article published on September 30, 2003

β-Ketoacyl-Acyl Carrier Protein Synthase III (FabH) Is Essential for Bacterial Fatty Acid Synthesis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M308638200
P953full work available at URLhttp://www.jbc.org/article/S0021925820754128/pdf
https://api.elsevier.com/content/article/PII:S0021925820754128?httpAccept=text/plain
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https://syndication.highwire.org/content/doi/10.1074/jbc.M308638200
P698PubMed publication ID14523010

P2093author name stringChiou-Yan Lai
John E. Cronan
P2860cites workA RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATIONQ25939000
The crystal structure of E. coli pantothenate synthetase confirms it as a member of the cytidylyltransferase superfamilyQ27632199
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR productsQ27860842
Regulation of coenzyme A biosynthesisQ28273878
Characterization of a Pseudomonas aeruginosa fatty acid biosynthetic gene cluster: purification of acyl carrier protein (ACP) and malonyl-coenzyme A:ACP transacylase (FabD)Q28493242
An efficient recombination system for chromosome engineering in Escherichia coliQ29615038
Conditional-replication, integration, excision, and retrieval plasmid-host systems for gene structure-function studies of bacteriaQ30731601
Overproduction of beta-ketoacyl-acyl carrier protein synthase I imparts thiolactomycin resistance to Escherichia coli K-12Q33273138
Low-redundancy sequencing of the entire Lactococcus lactis IL1403 genomeQ33757935
beta-ketoacyl-acyl carrier protein synthase III (FabH) is a determining factor in branched-chain fatty acid biosynthesisQ33993532
FabF is required for piezoregulation of cis-vaccenic acid levels and piezophilic growth of the deep-Sea bacterium Photobacterium profundum strain SS9Q33993903
Genetic Modification of Membrane LipidQ34008543
A missense mutation in the fabB (beta-ketoacyl-acyl carrier protein synthase I) gene confers tiolactomycin resistance to Escherichia coli.Q34107208
Escherichia coli as a model for the regulation of dissociable (type II) fatty acid biosynthesisQ34387800
Multi-subunit acetyl-CoA carboxylasesQ34744707
Electrospray ionization mass spectroscopic analysis of human erythrocyte plasma membrane phospholipidsQ35866657
Supercoiled circular DNA-protein complex in Escherichia coli: purification and induced conversion to an opern circular DNA formQ36450037
A collection of strains containing genetically linked alternating antibiotic resistance elements for genetic mapping of Escherichia coli.Q37055071
Beta-ketoacyl acyl carrier protein synthase III (FabH) is essential for fatty acid biosynthesis in Streptomyces coelicolor A3(2).Q39527279
Purification and characterization of fatty acyl-acyl carrier protein synthetase from Vibrio harveyiQ39926779
New and versatile cloning vectors with kanamycin-resistance markerQ48352251
Purification and activities of the Rhodobacter capsulatus RpoN (sigma N) protein.Q54585939
Electrospray ionization mass spectrometric analysis of phospholipids of Escherichia coli.Q54590813
Regulation of malonyl-CoA metabolism by acyl-acyl carrier protein and beta-ketoacyl-acyl carrier protein synthases in Escherichia coli.Q54610162
A soluble fatty acyl-acyl carrier protein synthetase from the bioluminescent bacterium Vibrio harveyiQ68576361
Enzymatic synthesis of beta-[U-14C]alanine and D-[1,2,3-14C]pantothenate of high specific radioactivityQ72138955
Chromatographic behaviour of isomeric long-chain aliphatic compounds. I. Thin-layer chromatography of some oxygenated fatty acid derivativesQ72655790
Biosynthesis of lipid A precursors in Escherichia coli. A cytoplasmic acyltransferase that converts UDP-N-acetylglucosamine to UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine.Q110199000
Isolation and characterization of the beta-ketoacyl-acyl carrier protein synthase III gene (fabH) from Escherichia coli K-12.Q115743546
P433issue51
P407language of work or nameEnglishQ1860
P921main subjectbiochemistryQ7094
cell biologyQ7141
fatty acidQ61476
P304page(s)51494-51503
P577publication date2003-09-30
P1433published inJournal of Biological ChemistryQ867727
P1476titleBeta-ketoacyl-acyl carrier protein synthase III (FabH) is essential for bacterial fatty acid synthesis
β-Ketoacyl-Acyl Carrier Protein Synthase III (FabH) Is Essential for Bacterial Fatty Acid Synthesis
P478volume278

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cites work (P2860)
Q92090558A Novel Gene Contributing to the Initiation of Fatty Acid Biosynthesis in Escherichia coli
Q54460714A genome rearrangement has orphaned the Escherichia coli K-12 AcpT phosphopantetheinyl transferase from its cognate Escherichia coli O157:H7 substrates.
Q35220686A homologue of the 3-oxoacyl-(acyl carrier protein) synthase III gene located in the glycosylation island of Pseudomonas syringae pv. tabaci regulates virulence factors via N-acyl homoserine lactone and fatty acid synthesis
Q34142701Adaptation to cold and proteomic responses of the psychrotrophic biopreservative Lactococcus piscium strain CNCM I-4031
Q24524159Alteration of the fatty acid profile of Streptomyces coelicolor by replacement of the initiation enzyme 3-ketoacyl acyl carrier protein synthase III (FabH).
Q38696811An integrative machine learning strategy for improved prediction of essential genes in Escherichia coli metabolism using flux-coupled features.
Q37807651Application and engineering of fatty acid biosynthesis in Escherichia coli for advanced fuels and chemicals
Q26829512Bacterial lipids: metabolism and membrane homeostasis
Q33842277Characterization of protein redox dynamics induced during light-to-dark transitions and nutrient limitation in cyanobacteria
Q33473123Cloning and sequence analysis of putative type II fatty acid synthase genes from Arachis hypogaea L.
Q27676144Combining functional and structural genomics to sample the essential Burkholderia structome
Q27656925Crystal structures of bacterial FabH suggest a molecular basis for the substrate specificity of the enzyme
Q92525511Diazaquinomycin Biosynthetic Gene Clusters from Marine and Freshwater Actinomycetes
Q35668053Dimerization of the bacterial biotin carboxylase subunit is required for acetyl coenzyme A carboxylase activity in vivo
Q24538774Discovery of FabH/FabF inhibitors from natural products
Q24674719Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties
Q50918080Dissection of the neocarazostatin: a C4 alkyl side chain biosynthesis by in vitro reconstitution.
Q49996981Efficient odd straight medium chain free fatty acid production by metabolically engineered Escherichia coli
Q51120231Engineering Escherichia coli to produce branched-chain fatty acids in high percentages.
Q28259142Enhanced production of branched-chain fatty acids by replacing β-ketoacyl-(acyl-carrier-protein) synthase III (FabH)
Q41200125Expression of Vibrio harveyi acyl-ACP synthetase allows efficient entry of exogenous fatty acids into the Escherichia coli fatty acid and lipid A synthetic pathways
Q36037219FabQ, a dual-function dehydratase/isomerase, circumvents the last step of the classical fatty acid synthesis cycle
Q28493145Fatty acid biosynthesis in Pseudomonas aeruginosa is initiated by the FabY class of β-ketoacyl acyl carrier protein synthases
Q28660457Fatty acid synthesis in Escherichia coli and its applications towards the production of fatty acid based biofuels
Q33979089Functional replacement of the FabA and FabB proteins of Escherichia coli fatty acid synthesis by Enterococcus faecalis FabZ and FabF homologues
Q90204231Genetic and Chemical-Genetic Interactions Map Biogenesis and Permeability Determinants of the Outer Membrane of Escherichia coli
Q27028222Genetic resources for advanced biofuel production described with the Gene Ontology
Q37424941Genomic Landscape of Intrahost Variation in Group A Streptococcus: Repeated and Abundant Mutational Inactivation of the fabT Gene Encoding a Regulator of Fatty Acid Synthesis
Q36464020Inhibiting bacterial fatty acid synthesis
Q41517603Lactococcus lactis fabH, encoding beta-ketoacyl-acyl carrier protein synthase, can be functionally replaced by the Plasmodium falciparum congener.
Q34406049Mechanisms of self-resistance in the platensimycin- and platencin-producing Streptomyces platensis MA7327 and MA7339 strains.
Q51541096Microbial production of bi-functional molecules by diversification of the fatty acid pathway.
Q24812834Modeling Lactococcus lactis using a genome-scale flux model
Q46032138Modular pathway engineering for the microbial production of branched-chain fatty alcohols.
Q83943548Molecular dynamics and docking simulations as a proof of high flexibility in E. coli FabH and its relevance for accurate inhibitor modeling
Q38148202Novel FabH inhibitors: an updated article literature review (July 2012 to June 2013).
Q36052586Parasite plastids: approaching the endgame
Q38468310Platensimycin is a selective FabF inhibitor with potent antibiotic properties
Q35754601Ralstonia solanacearum RSp0194 Encodes a Novel 3-Keto-Acyl Carrier Protein Synthase III
Q57819618Rapid determination of biosynthetic pathways using fractional isotope enrichment and high-resolution dynamic nuclear polarization enhanced NMR
Q38124842Recent advances in inhibitors of bacterial fatty acid synthesis type II (FASII) system enzymes as potential antibacterial agents
Q36280073Regulation of cell size in response to nutrient availability by fatty acid biosynthesis in Escherichia coli
Q41722339Retrieval of Enterobacteriaceae drug targets using singular value decomposition
Q36690781Shewanella oneidensis FabB: A β-ketoacyl-ACP Synthase That Works with C16:1-ACP.
Q47106726Structural evidence for the covalent modification of FabH by 4,5-dichloro-1,2-dithiol-3-one (HR45).
Q27649337Structure-assisted discovery of an aminothiazole derivative as a lead molecule for inhibition of bacterial fatty-acid synthesis
Q41844519Substrate recognition by β-ketoacyl-ACP synthases.
Q39442654Suppression of fabB Mutation by fabF1 Is Mediated by Transcription Read-through in Shewanella oneidensis.
Q41746413The Fatty Acid Regulator FadR Influences the Expression of the Virulence Cascade in the El Tor Biotype of Vibrio cholerae by Modulating the Levels of ToxT via Two Different Mechanisms
Q33660653The Lactococcus lactis FabF fatty acid synthetic enzyme can functionally replace both the FabB and FabF proteins of Escherichia coli and the FabH protein of Lactococcus lactis
Q46465470The Production of Curli Amyloid Fibers Is Deeply Integrated into the Biology of Escherichia coli.
Q35362525The surfactant of Legionella pneumophila Is secreted in a TolC-dependent manner and is antagonistic toward other Legionella species
Q44369412Transcriptional regulation of fatty acid biosynthesis in Streptococcus pneumoniae
Q46524369Transcriptional response of Escherichia coli to temperature shift
Q37173688Transcriptomic Responses of the Interactions between Clostridium cellulovorans 743B and Rhodopseudomonas palustris CGA009 in a Cellulose-Grown Coculture for Enhanced Hydrogen Production
Q57244151Type II fatty acid synthesis is not a suitable antibiotic target for Gram-positive pathogens
Q28080940Using modern tools to probe the structure-function relationship of fatty acid synthases
Q36276335Will the initiator of fatty acid synthesis in Pseudomonas aeruginosa please stand up?
Q37232899Xanthomonas campestris FabH is required for branched-chain fatty acid and DSF-family quorum sensing signal biosynthesis
Q55431582fabH deletion increases DHA production in Escherichia coli expressing Pfa genes.

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