| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2003Sci...302.2137N |
| P356 | DOI | 10.1126/SCIENCE.1092481 |
| P698 | PubMed publication ID | 14684824 |
| P50 | author | Manabu Sugai | Q126200547 |
| P2093 | author name string | Yasutoshi Agata | |
| Akira Shimizu | |||
| Hiroyuki Gonda | |||
| Tomoya Katakai | |||
| Yoshifumi Yokota | |||
| Yukiko Nambu | |||
| Chung-Gi Lee | |||
| P433 | issue | 5653 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 2137-2140 | |
| P577 | publication date | 2003-12-01 | |
| P1433 | published in | Science | Q192864 |
| P1476 | title | Transcription-coupled events associating with immunoglobulin switch region chromatin | |
| P478 | volume | 302 |
| Q37620941 | "Cotranscriptionality": the transcription elongation complex as a nexus for nuclear transactions |
| Q48277866 | 53BP1 Contributes to Igh Locus Chromatin Topology during Class Switch Recombination |
| Q48158448 | A broad atlas of somatic hypermutation allows prediction of activation-induced deaminase targets. |
| Q33605445 | A coming-of-age story: activation-induced cytidine deaminase turns 10. |
| Q52723490 | A licensing step links AID to transcription elongation for mutagenesis in B cells. |
| Q36403922 | A role for Msh6 but not Msh3 in somatic hypermutation and class switch recombination |
| Q36340835 | A role for the RNA pol II-associated PAF complex in AID-induced immune diversification |
| Q34133261 | A source of the single-stranded DNA substrate for activation-induced deaminase during somatic hypermutation |
| Q38680202 | A transcriptional serenAID: the role of noncoding RNAs in class switch recombination |
| Q30537745 | AID and Apobec3G haphazard deamination and mutational diversity |
| Q34118000 | AID and somatic hypermutation. |
| Q37164471 | AID hits the jackpot when missing the target |
| Q33839428 | AID induces double-strand breaks at immunoglobulin switch regions and c-MYC causing chromosomal translocations in yeast THO mutants |
| Q27692655 | AID targeting is dependent on RNA polymerase II pausing |
| Q36170796 | AID to overcome the limitations of genomic information |
| Q41887653 | AID- and Ung-dependent generation of staggered double-strand DNA breaks in immunoglobulin class switch DNA recombination: a post-cleavage role for AID. |
| Q90362370 | AID-RNA polymerase II transcription-dependent deamination of IgV DNA |
| Q40328411 | AID-dependent histone acetylation is detected in immunoglobulin S regions |
| Q36845671 | AID-initiated purposeful mutations in immunoglobulin genes |
| Q37815430 | AID: a riddle wrapped in a mystery inside an enigma |
| Q37683558 | AIDing Chromatin and Transcription-Coupled Orchestration of Immunoglobulin Class-Switch Recombination. |
| Q36399334 | ATM is required for efficient recombination between immunoglobulin switch regions |
| Q37512363 | Activation-induced cytidine deaminase (AID) can target both DNA strands when the DNA is supercoiled |
| Q35709088 | Activation-induced cytidine deaminase (AID)-dependent somatic hypermutation requires a splice isoform of the serine/arginine-rich (SR) protein SRSF1 |
| Q34427913 | Activation-induced cytidine deaminase alters the subcellular localization of Tet family proteins |
| Q28284694 | Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming |
| Q37994933 | Activation-induced cytidine deaminase in antibody diversification and chromosome translocation |
| Q34357060 | Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5 |
| Q40566152 | Activation-induced cytosine deaminase (AID) is actively exported out of the nucleus but retained by the induction of DNA breaks |
| Q36508536 | Activation-induced deaminase-mediated class switch recombination is blocked by anti-IgM signaling in a phosphatidylinositol 3-kinase-dependent fashion |
| Q27337984 | Activation-induced deoxycytidine deaminase (AID) co-transcriptional scanning at single-molecule resolution. |
| Q41733193 | Active RNAP pre-initiation sites are highly mutated by cytidine deaminases in yeast, with AID targeting small RNA genes. |
| Q45143151 | An evolutionarily conserved target motif for immunoglobulin class-switch recombination |
| Q36949047 | Analysis of intergenic transcription and histone modification across the human immunoglobulin heavy-chain locus |
| Q36231123 | Antibody class switch recombination: roles for switch sequences and mismatch repair proteins |
| Q45174128 | Antibody diversity: one enzyme to rule them all. |
| Q47703435 | Antisense intergenic transcription in V(D)J recombination |
| Q33656131 | Attracting AID to targets of somatic hypermutation |
| Q34427857 | B cells from hyper-IgM patients carrying UNG mutations lack ability to remove uracil from ssDNA and have elevated genomic uracil |
| Q40329923 | Biased dA/dT somatic hypermutation as regulated by the heavy chain intronic iEmu enhancer and 3'Ealpha enhancers in human lymphoblastoid B cells |
| Q36124379 | Binding of LBP-1a to specific immunoglobulin switch regions in vivo correlates with specific repression of class switch recombination |
| Q36973654 | Changes in RNA polymerase II progression influence somatic hypermutation of Ig-related genes by AID |
| Q33823918 | Chromatin architecture near a potential 3' end of the igh locus involves modular regulation of histone modifications during B-Cell development and in vivo occupancy at CTCF sites |
| Q33299578 | Chromatin structure regulates gene conversion |
| Q36769461 | Class switch recombination: a comparison between mouse and human. |
| Q28269740 | Class-switch recombination: interplay of transcription, DNA deamination and DNA repair |
| Q36316915 | Combinatorial mechanisms regulating AID-dependent DNA deamination: interacting proteins and post-translational modifications |
| Q84974896 | Combined deficiency of MSH2 and Sμ region abolishes class switch recombination |
| Q34958445 | Complex regulation and function of activation-induced cytidine deaminase |
| Q36228204 | Control of gene conversion and somatic hypermutation by immunoglobulin promoter and enhancer sequences |
| Q34189624 | Controlling somatic hypermutation in immunoglobulin variable and switch regions |
| Q36015019 | DNA deamination in immunity |
| Q36229513 | DNA polymerase beta is able to repair breaks in switch regions and plays an inhibitory role during immunoglobulin class switch recombination |
| Q37397523 | DNA targets of AID evolutionary link between antibody somatic hypermutation and class switch recombination |
| Q53656220 | Decision criteria for resolving isotype switching conflicts by B cells. |
| Q33757410 | Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes |
| Q36228903 | Detection of chromatin-associated single-stranded DNA in regions targeted for somatic hypermutation. |
| Q37593556 | Differential regulation of histone acetylation and generation of mutations in switch regions is associated with Ig class switching |
| Q36845653 | Discovery of activation-induced cytidine deaminase, the engraver of antibody memory |
| Q24623341 | Endonuclease G plays a role in immunoglobulin class switch DNA recombination by introducing double-strand breaks in switch regions |
| Q34831630 | Epigenetic targeting of activation-induced cytidine deaminase. |
| Q26772330 | Epigenetics of Peripheral B-Cell Differentiation and the Antibody Response |
| Q37097751 | Epigenetics of the antibody response |
| Q55011560 | Epigenomic Modifications Mediating Antibody Maturation. |
| Q36389685 | Evaluation of molecular models for the affinity maturation of antibodies: roles of cytosine deamination by AID and DNA repair |
| Q36845675 | Evolution of the immunoglobulin heavy chain class switch recombination mechanism |
| Q38019962 | Evolutionary comparison of the mechanism of DNA cleavage with respect to immune diversity and genomic instability |
| Q28589828 | Examination of Msh6- and Msh3-deficient mice in class switching reveals overlapping and distinct roles of MutS homologues in antibody diversification |
| Q33947867 | Expression of activation-induced cytidine deaminase is regulated by cell division, providing a mechanistic basis for division-linked class switch recombination |
| Q37692338 | Extension of the germinal center stage of B cell development promotes autoantibodies in BXD2 mice |
| Q33551464 | Fanconi anemia protein FANCD2 promotes immunoglobulin gene conversion and DNA repair through a mechanism related to homologous recombination |
| Q38943944 | Functions and Malfunctions of Mammalian DNA-Cytosine Deaminases |
| Q37832456 | Functions of Runx in IgA class switch recombination |
| Q36906733 | GANP regulates recruitment of AID to immunoglobulin variable regions by modulating transcription and nucleosome occupancy |
| Q34025211 | GANP-mediated recruitment of activation-induced cytidine deaminase to cell nuclei and to immunoglobulin variable region DNA. |
| Q38202855 | Genetic diversification by somatic gene conversion |
| Q28266306 | Genome instability: a mechanistic view of its causes and consequences |
| Q37124102 | H3 trimethyl K9 and H3 acetyl K9 chromatin modifications are associated with class switch recombination |
| Q36091851 | H4K16 acetylation affects recombination and ncRNA transcription at rDNA in Saccharomyces cerevisiae. |
| Q34031388 | High resolution analysis of the chromatin landscape of the IgE switch region in human B cells |
| Q24300395 | Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation |
| Q34647217 | Histone deacetylase inhibitors upregulate B cell microRNAs that silence AID and Blimp-1 expression for epigenetic modulation of antibody and autoantibody responses |
| Q48268350 | Histone methyltransferase MMSET promotes AID-mediated DNA breaks at the donor switch region during class switch recombination. |
| Q40273513 | IGH switch breakpoints in Burkitt lymphoma: exclusive involvement of noncanonical class switch recombination |
| Q56749508 | Identification of a specific domain required for dimerization of activation-induced cytidine deaminase |
| Q45111031 | Identification of an AID-independent pathway for chromosomal translocations between the Igh switch region and Myc. |
| Q42972358 | Identifying protein-protein interactions in somatic hypermutation |
| Q37273114 | Ikaros controls isotype selection during immunoglobulin class switch recombination |
| Q24647660 | Immunoglobulin class switch recombination is impaired in Atm-deficient mice |
| Q36534234 | Immunoglobulin class-switch DNA recombination: induction, targeting and beyond |
| Q37273168 | Immunoglobulin switch mu sequence causes RNA polymerase II accumulation and reduces dA hypermutation. |
| Q45030696 | Immunology: aid for AID. |
| Q33328760 | Impact of phosphorylation and phosphorylation-null mutants on the activity and deamination specificity of activation-induced cytidine deaminase |
| Q40464870 | Interaction of HTLV-1 Tax and methyl-CpG-binding domain 2 positively regulates the gene expression from the hypermethylated LTR. |
| Q37138006 | Interference of mismatch and base excision repair during the processing of adjacent U/G mispairs may play a key role in somatic hypermutation |
| Q35792957 | Known components of the immunoglobulin A:T mutational machinery are intact in Burkitt lymphoma cell lines with G:C bias |
| Q37748073 | Long noncoding RNAs: implications for antigen receptor diversification |
| Q36037736 | Mechanism and control of V(D)J recombination versus class switch recombination: similarities and differences |
| Q34764888 | Mechanism and regulation of class switch recombination |
| Q35992414 | Mice lacking Sμ tandem repeats maintain RNA polymerase patterns but exhibit histone modification pattern shifts linked to class switch site locations |
| Q33688205 | MicroRNA activity in B lymphocytes |
| Q87129183 | Mir-17-92 regulates bone marrow homing of plasma cells and production of immunoglobulin G2c |
| Q35488455 | Mitochondrial function provides instructive signals for activation-induced B-cell fates |
| Q40009105 | Modulation of immunoglobulin gene conversion frequency and distribution by the histone deacetylase HDAC2 in chicken DT40. |
| Q37851179 | Molecular mechanism of immunoglobulin V-region diversification regulated by transcription and RNA metabolism in antigen-driven B cells |
| Q26768663 | Mutations, kataegis and translocations in B cells: understanding AID promiscuous activity |
| Q37164511 | NF-kappa B binds to the immunoglobulin S gamma 3 region in vivo during class switch recombination |
| Q35589869 | Non-coding RNA Generated following Lariat Debranching Mediates Targeting of AID to DNA |
| Q40029354 | Nuclear Exclusion of the HIV-1 host defense factor APOBEC3G requires a novel cytoplasmic retention signal and is not dependent on RNA binding. |
| Q35128767 | Overlapping hotspots in CDRs are critical sites for V region diversification |
| Q28585503 | PTIP promotes chromatin changes critical for immunoglobulin class switch recombination |
| Q47108181 | Physiological Roles of DNA Double-Strand Breaks |
| Q37326092 | Post-translational regulation of activation-induced cytidine deaminase |
| Q36699771 | Proteasomal degradation restricts the nuclear lifespan of AID |
| Q28087424 | RNA Exosome Regulates AID DNA Mutator Activity in the B Cell Genome |
| Q37730047 | Regulating infidelity: RNA-mediated recruitment of AID to DNA during class switch recombination |
| Q26853622 | Regulation of Aicda expression and AID activity |
| Q24633098 | Regulation of aicda expression and AID activity: relevance to somatic hypermutation and class switch DNA recombination |
| Q34115234 | Regulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair |
| Q36300042 | Replacement of Igamma3 germ-line promoter by Igamma1 inhibits class-switch recombination to IgG3. |
| Q31099047 | Replication protein A interacts with AID to promote deamination of somatic hypermutation targets |
| Q36487660 | Retinoic acid promotes mouse splenic B cell surface IgG expression and maturation stimulated by CD40 and IL-4. |
| Q35797150 | Role of Id proteins in B lymphocyte activation: new insights from knockout mouse studies |
| Q34308191 | Roles for histone H3K4 methyltransferase activities during immunoglobulin class-switch recombination |
| Q38438140 | Seeking sense of antisense switch transcripts. |
| Q42739452 | Sense transcription through the S region is essential for immunoglobulin class switch recombination. |
| Q28505280 | Shifts in targeting of class switch recombination sites in mice that lack mu switch region tandem repeats or Msh2 |
| Q37241469 | Single nucleotide changes in the human Igamma1 and Igamma4 promoters underlie different transcriptional responses to CD40. |
| Q24307502 | Solubility-based genetic screen identifies RING finger protein 126 as an E3 ligase for activation-induced cytidine deaminase |
| Q36399510 | Somatic hypermutation is limited by CRM1-dependent nuclear export of activation-induced deaminase |
| Q35978867 | Somatic hypermutation: a mutational panacea |
| Q34217718 | Specific recruitment of protein kinase A to the immunoglobulin locus regulates class-switch recombination |
| Q44623657 | Stabilised DNA secondary structures with increasing transcription localise hypermutable bases for somatic hypermutation in IGHV3-23. |
| Q79427918 | Stimuli that enhance IgA class switching increase histone 3 acetylation at S alpha, but poorly stimulate sequential switching from IgG2b |
| Q36845667 | Targeting of AID-mediated sequence diversification by cis-acting determinants |
| Q34551108 | Targeting of somatic hypermutation |
| Q37994927 | The AID dilemma: infection, or cancer? |
| Q34715036 | The AID-induced DNA damage response in chromatin |
| Q24337929 | The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates |
| Q42286497 | The in vivo pattern of AID targeting to immunoglobulin switch regions deduced from mutation spectra in msh2-/- ung-/- mice |
| Q36150234 | The phosphoinositide 3-kinase signaling pathway in normal and malignant B cells: activation mechanisms, regulation and impact on cellular functions. |
| Q36231119 | The repair of DNA damages/modifications during the maturation of the immune system: lessons from human primary immunodeficiency disorders and animal models. |
| Q36845661 | The role of activation-induced deaminase in antibody diversification and chromosome translocations |
| Q38357746 | The two-component system BfrAB regulates expression of ABC transporters in Streptococcus gordonii and Streptococcus sanguinis |
| Q36403120 | The very 5' end and the constant region of Ig genes are spared from somatic mutation because AID does not access these regions |
| Q36235676 | Three-dimensional architecture of the IgH locus facilitates class switch recombination |
| Q91844697 | Transcription factor binding at Ig enhancers is linked to somatic hypermutation targeting |
| Q21194855 | Transcription-coupled mutagenesis by the DNA deaminase AID |
| Q37061670 | Transcriptional pausing and stalling causes multiple clustered mutations by human activation-induced deaminase |
| Q40522938 | Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch |
| Q34063549 | Vitamin A and immune function: retinoic acid modulates population dynamics in antigen receptor and CD38-stimulated splenic B cells |
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