The central nervous system is a viral reservoir in simian immunodeficiency virus--infected macaques on combined antiretroviral therapy: a model for human immunodeficiency virus patients on highly active antiretroviral therapy

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The central nervous system is a viral reservoir in simian immunodeficiency virus--infected macaques on combined antiretroviral therapy: a model for human immunodeficiency virus patients on highly active antiretroviral therapy is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1015893542
P356DOI10.1080/13550280590922748
P698PubMed publication ID16036796
P5875ResearchGate publication ID7708327

P2093author name stringMing Li
Janice E Clements
M Christine Zink
Joseph L Mankowski
Lucio Gama
Brandon Bullock
Lucy M Carruth
P2860cites workIdentification of a reservoir for HIV-1 in patients on highly active antiretroviral therapyQ28253761
Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapyQ29615992
Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapyQ29615993
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The changing pattern of HIV neuropathology in the HAART era.Q30797688
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High viral load in the cerebrospinal fluid and brain correlates with severity of simian immunodeficiency virus encephalitis.Q33825647
HIV-1 can be recovered from a variety of cells including peripheral blood monocytes of patients receiving highly active antiretroviral therapy: a further obstacle to eradicationQ33917711
Molecular analysis of cerebrospinal fluid: potential for the study of HIV-1 infection of the central nervous systemQ33953033
The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitorsQ34065800
Basic principles of immunological surveillance of the normal central nervous systemQ34398602
Reservoirs for HIV infection and their persistence in the face of undetectable viral loadQ34426036
Resting CD4+ T lymphocytes but not thymocytes provide a latent viral reservoir in a simian immunodeficiency virus-Macaca nemestrina model of human immunodeficiency virus type 1-infected patients on highly active antiretroviral therapyQ34857454
Searching for clues: tracking the pathogenesis of human immunodeficiency virus central nervous system disease by use of an accelerated, consistent simian immunodeficiency virus macaque modelQ34993089
A novel simian immunodeficiency virus model that provides insight into mechanisms of human immunodeficiency virus central nervous system diseaseQ35030075
Changing patterns in the neuropathogenesis of HIV during the HAART era.Q35126422
Antiviral treatment normalizes neurophysiological but not movement abnormalities in simian immunodeficiency virus-infected monkeysQ35128071
Patterns of viral replication correlate with outcome in simian immunodeficiency virus (SIV)-infected macaques: effect of prior immunization with a trivalent SIV vaccine in modified vaccinia virus Ankara.Q35861490
Molecular and biological characterization of a neurovirulent molecular clone of simian immunodeficiency virusQ35889564
Pathogenesis of simian immunodeficiency virus encephalitis: viral determinants of neurovirulenceQ35890115
Evidence for human immunodeficiency virus type 1 replication in vivo in CD14(+) monocytes and its potential role as a source of virus in patients on highly active antiretroviral therapyQ39685944
Relative potency of protease inhibitors in monocytes/macrophages acutely and chronically infected with human immunodeficiency virus.Q41018028
Expression kinetics and subcellular localization of HIV-1 regulatory proteins Nef, Tat and Rev in acutely and chronically infected lymphoid cell linesQ41504229
Time course of cerebrospinal fluid responses to antiretroviral therapy: evidence for variable compartmentalization of infection.Q41677720
Cerebrospinal fluid HIV RNA originates from both local CNS and systemic sourcesQ41721709
Changes in pathological findings at autopsy in AIDS cases for the last 15 yearsQ41724548
Anti-retrovirus activity of 9-(2-phosphonylmethoxyethyl)adenine (PMEA) in vivo increases when it is less frequently administeredQ42831609
Plasma SIV RNA viral load determination by real-time quantification of product generation in reverse transcriptase-polymerase chain reactionQ44244285
Beta-chemokines MCP-1 and RANTES are selectively increased in cerebrospinal fluid of patients with human immunodeficiency virus-associated dementiaQ44253971
Cerebrospinal fluid HIV-1 RNA during treatment with ritonavir/saquinavir or ritonavir/saquinavir/stavudineQ44527304
The central nervous system as a reservoir for simian immunodeficiency virus (SIV): steady-state levels of SIV DNA in brain from acute through asymptomatic infectionQ45730919
Increased macrophage chemoattractant protein-1 in cerebrospinal fluid precedes and predicts simian immunodeficiency virus encephalitisQ45735521
Comparative assessment of antiretrovirals in human monocyte-macrophages and lymphoid cell lines acutely and chronically infected with the human immunodeficiency virusQ45846545
HIV-related neuropathology, 1985 to 1999: rising prevalence of HIV encephalopathy in the era of highly active antiretroviral therapyQ46103833
Quantifying residual HIV-1 replication in patients receiving combination antiretroviral therapyQ47960975
HIV-1 infection of subcortical astrocytes in the pediatric central nervous systemQ48162348
Overexpression of nef as a marker for restricted HIV-1 infection of astrocytes in postmortem pediatric central nervous tissuesQ48162358
Astrocytes: HIV cellular reservoirs and important participants in neuropathogenesisQ48235017
Effect of genotypic resistance on the virological response to highly active antiretroviral therapy in cerebrospinal fluidQ48372719
Cervical lymphatics, the blood-brain barrier and the immunoreactivity of the brain: a new viewQ48400195
In vitro blood-brain barrier permeability of nevirapine compared to other HIV antiretroviral agentsQ48497171
Monocytes harbour replication-competent, non-latent HIV-1 in patients on highly active antiretroviral therapy.Q52021616
Detection of infectious HIV in circulating monocytes from patients on prolonged highly active antiretroviral therapy.Q54057499
Persistence of HIV-1 Transcription in Peripheral-Blood Mononuclear Cells in Patients Receiving Potent Antiretroviral TherapyQ57075703
In vitro activity of inhibitors of late stages of the replication of HIV in chronically infected macrophagesQ72182519
Investigation of distribution, transport and uptake of anti-HIV drugs to the central nervous systemQ73850558
Neuropathology and general autopsy findings in AIDS during the last 15 yearsQ74237358
Changes to AIDS dementia complex in the era of highly active antiretroviral therapyQ78029535
P433issue2
P921main subjectpatientQ181600
Simian immunodeficiency virusQ1890246
anti-retroviral agentQ50430310
P304page(s)180-189
P577publication date2005-04-01
P1433published inJournal of NeuroVirologyQ6295640
P1476titleThe central nervous system is a viral reservoir in simian immunodeficiency virus--infected macaques on combined antiretroviral therapy: a model for human immunodeficiency virus patients on highly active antiretroviral therapy
P478volume11

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