Clonal relationships of CSF B cells in treatment-naive multiple sclerosis patients.

scientific article published on 16 November 2017

Clonal relationships of CSF B cells in treatment-naive multiple sclerosis patients. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1172/JCI.INSIGHT.92724
P932PMC publication ID5752381
P698PubMed publication ID29202449

P50authorStephen L. HauserQ7609730
Michael R WilsonQ56434547
Hans-Christian von BüdingenQ73517832
Antje BischofQ85643745
Stanislas DemuthQ89476296
Ariele L GreenfieldQ102220100
Erica L EggersQ114403604
Aya AbounasrQ125288548
Natalie S PiersonQ125289085
P2093author name stringHao Wu
Carolyn J Bevan
Bruce Ac Cree
Roland G Henry
Brady A Michel
Sheng-Zhi Wang
Elizabeth Leitner
Max Kazer
P2860cites workCerebrospinal fluid B cells correlate with early brain inflammation in multiple sclerosisQ21144285
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Ocrelizumab in relapsing-remitting multiple sclerosis: a phase 2, randomised, placebo-controlled, multicentre trialQ34229618
Performance comparison of benchtop high-throughput sequencing platformsQ34241334
Immunoglobulin class-switched B cells form an active immune axis between CNS and periphery in multiple sclerosis.Q34251673
Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic proteinQ34293468
The cerebrospinal fluid immunoglobulin transcriptome and proteome in neuromyelitis optica reveals central nervous system-specific B cell populationsQ34459965
Gadolinium-based MRI characterization of leptomeningeal inflammation in multiple sclerosisQ34472457
Expansion of CD27high plasmablasts in transverse myelitis patients that utilize VH4 and JH6 genes and undergo extensive somatic hypermutation.Q35077861
Functional capacities of human IgM memory B cells in early inflammatory responses and secondary germinal center reactionsQ35090021
B-cell subsets in the joint compartments of seropositive and seronegative rheumatoid arthritis (RA) and No-RA arthritides express memory markers and ZAP70 and characterize the aggregate pattern irrespectively of the autoantibody status.Q35286950
B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodesQ35298764
Rituximab reduces B cells and T cells in cerebrospinal fluid of multiple sclerosis patientsQ35585366
The search for the target antigens of multiple sclerosis, part 2: CD8+ T cells, B cells, and antibodies in the focus of reverse-translational researchQ35883319
B cell repertoire expansion occurs in meningeal ectopic lymphoid tissue.Q36220292
B cell exchange across the blood-brain barrier in multiple sclerosisQ36498036
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Specific peripheral B cell tolerance defects in patients with multiple sclerosisQ36890946
Recapitulation of B cell differentiation in the central nervous system of patients with multiple sclerosis.Q37285430
Clonal expansion and somatic hypermutation of V(H) genes of B cells from cerebrospinal fluid in multiple sclerosis.Q37385073
Onset of secondary progressive MS after long-term rituximab therapy - a case report.Q37572960
In multiple sclerosis, oligoclonal bands connect to peripheral B-cell responses.Q37652977
Ocrelizumab versus Placebo in Primary Progressive Multiple SclerosisQ40400256
Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple SclerosisQ40400262
Human blood IgM "memory" B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoireQ41505077
B cell repertoire diversity and clonal expansion in multiple sclerosis brain lesionsQ41697260
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Intrathecal somatic hypermutation of IgM in multiple sclerosis and neuroinflammationQ44681284
Rituximab in relapsing-remitting multiple sclerosis: a 72-week, open-label, phase I trialQ45119459
Cerebrospinal fluid parameters of B cell-related activity in patients with active disease during natalizumab therapyQ45405778
Safety and efficacy of ofatumumab in relapsing-remitting multiple sclerosis: a phase 2 studyQ45890653
The risk of relapses in multiple sclerosis during systemic infectionsQ46129279
Comparative analysis of the CD19+ and CD138+ cell antibody repertoires in the cerebrospinal fluid of patients with multiple sclerosisQ47309556
Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis.Q47357498
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Clonally expanded plasma cells in the cerebrospinal fluid of patients with central nervous system autoimmune demyelination produce "oligoclonal bands".Q48412765
Rituximab in patients with primary progressive multiple sclerosis: results of a randomized double-blind placebo-controlled multicenter trial.Q48427388
Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitmentQ48701331
Short-lived plasma blasts are the main B cell effector subset during the course of multiple sclerosisQ48949365
Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosisQ48949792
Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis.Q51027456
Matching of oligoclonal immunoglobulin transcriptomes and proteomes of cerebrospinal fluid in multiple sclerosis.Q54180855
Multiple sclerosis: BAFF and CXCL13 in cerebrospinal fluidQ59543689
Lymphocyte Subpopulations in the Cerebrospinal Fluid and Peripheral Blood in Patients with Multiple SclerosisQ66881982
Analysis of multiple sclerosis cerebrospinal fluid reveals a continuum of clonally related antibody-secreting cells that are predominantly plasma blastsQ81588164
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Conversion from clinically isolated syndrome to multiple sclerosis: A large multicentre studyQ85291118
P4510describes a project that usesCytoscapeQ3699942
P433issue22
P577publication date2017-11-16
P1433published inJCI insightQ27727187
P1476titleClonal relationships of CSF B cells in treatment-naive multiple sclerosis patients
P478volume2

Reverse relations

cites work (P2860)
Q89943881A New Risk Variant for Multiple Sclerosis at 11q23.3 Locus Is Associated with Expansion of CXCR5+ Circulating Regulatory T Cells
Q88161098Antibody repertoire analysis in polygenic autoimmune diseases
Q46583404B Cell Therapy for Multiple Sclerosis: Entering an Era.
Q104479846B cell depletion therapies in autoimmune disease: advances and mechanistic insights
Q91236273B cells in autoimmune and neurodegenerative central nervous system diseases
Q92712543Central Nervous System Inflammatory Aggregates in the Theiler's Virus Model of Progressive Multiple Sclerosis
Q52650355Cladribine treatment of multiple sclerosis is associated with depletion of memory B cells.
Q52577393Human central nervous system astrocytes support survival and activation of B cells: implications for MS pathogenesis.
Q92339537Induction of brain-infiltrating T-bet-expressing B cells in multiple sclerosis
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Q91728778Primary vitreoretinal lymphomas display a remarkably restricted immunoglobulin gene repertoire
Q89171079Reassessing B cell contributions in multiple sclerosis
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Q96306924[Ocrelizumab for treatment of multiple sclerosis]

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