Longitudinally persistent cerebrospinal fluid B cells can resist treatment in multiple sclerosis

scientific article published on 21 March 2019

Longitudinally persistent cerebrospinal fluid B cells can resist treatment in multiple sclerosis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1172/JCI.INSIGHT.126599
P932PMC publication ID6482992
P698PubMed publication ID30747723

P50authorStephen L. HauserQ7609730
Antje BischofQ85643745
Ariele L GreenfieldQ102220100
Erica L EggersQ114403604
Akshaya RameshQ114403622
Natalie S PiersonQ125289085
Michael R WilsonQ56434547
P2093author name stringHao Wu
Martin S Weber
Bruce Ac Cree
Roland G Henry
H-Christian von Büdingen
Sarah Laurent
Ravi Dandekar
William Harkin
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Intrathecally synthesized IgG in multiple sclerosis cerebrospinal fluid recognizes identical epitopes over timeQ34073320
Immunoglobulin class-switched B cells form an active immune axis between CNS and periphery in multiple sclerosis.Q34251673
Related B cell clones populate the meninges and parenchyma of patients with multiple sclerosisQ34538912
IgBLAST: an immunoglobulin variable domain sequence analysis toolQ34720205
Related B cell clones that populate the CSF and CNS of patients with multiple sclerosis produce CSF immunoglobulinQ34960518
MENINGEAL INFLAMMATION AND CORTICAL DEMYELINATION IN ACUTE MULTIPLE SCLEROSISQ58552252
Peripheral B cell depletion and central proinflammatory cytokine reduction following repeated intrathecal administration of rituximab in progressive Multiple SclerosisQ61230854
A new primate model for multiple sclerosis in the common marmosetQ73822837
Regeneration of B cell subsets after transient B cell depletion using anti-CD20 antibodies in rheumatoid arthritisQ79992105
IMGT/V-QUEST: IMGT standardized analysis of the immunoglobulin (IG) and T cell receptor (TR) nucleotide sequencesQ84245408
The Multiple Roles of B Cells in Multiple Sclerosis and Their Implications in Multiple Sclerosis TherapiesQ88376284
Functional capacities of human IgM memory B cells in early inflammatory responses and secondary germinal center reactionsQ35090021
B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodesQ35298764
Naive antibody gene-segment frequencies are heritable and unaltered by chronic lymphocyte ablationQ35647840
A germinal center-independent pathway generates unswitched memory B cells early in the primary responseQ35825984
The Charcot Lecture | beating MS: a story of B cells, with twists and turnsQ36086475
B cell repertoire expansion occurs in meningeal ectopic lymphoid tissue.Q36220292
Cellular Dynamics of Memory B Cell Populations: IgM+ and IgG+ Memory B Cells Persist Indefinitely as Quiescent CellsQ36260505
Temporal invariance and clonal uniformity of brain and cerebrospinal IgG, IgA, and IgM in multiple sclerosisQ36351504
Insufficient disease inhibition by intrathecal rituximab in progressive multiple sclerosisQ36639659
Lineage tracing of human B cells reveals the in vivo landscape of human antibody class switchingQ37146773
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B cells as therapeutic targets in autoimmune neurological disordersQ37278022
Recapitulation of B cell differentiation in the central nervous system of patients with multiple sclerosis.Q37285430
MHC class II-dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodiesQ37397820
Long-term evolution of multiple sclerosis disability in the treatment era.Q37409279
Eye on the B-ALL: B-cell receptor repertoires reveal persistence of numerous B-lymphoblastic leukemia subclones from diagnosis to relapse.Q37500642
Onset of secondary progressive MS after long-term rituximab therapy - a case report.Q37572960
In multiple sclerosis, oligoclonal bands connect to peripheral B-cell responses.Q37652977
Ectopic lymphoid-like structures in infection, cancer and autoimmunityQ38221815
Greater sensitivity to multiple sclerosis disability worsening and progression events using a roving versus a fixed reference value in a prospective cohort studyQ38758444
Memory B Cells are Major Targets for Effective Immunotherapy in Relapsing Multiple SclerosisQ39119839
Ocrelizumab versus Placebo in Primary Progressive Multiple SclerosisQ40400256
Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple SclerosisQ40400262
B Cell Reconstitution after Rituximab Treatment in Idiopathic Nephrotic SyndromeQ41124267
Oligoclonal "fingerprint" of CSF IgG in multiple sclerosis patients is not modified following intrathecal administration of natural beta-interferonQ42583785
Maintenance of B lymphocyte-related clones in the cerebrospinal fluid of multiple sclerosis patientsQ42613948
B Cell Therapy for Multiple Sclerosis: Entering an Era.Q46583404
Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis.Q47357498
Clonal relationships of CSF B cells in treatment-naive multiple sclerosis patients.Q47935420
MiXCR: software for comprehensive adaptive immunity profiling.Q48193977
Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology.Q48200750
Clonally expanded plasma cells in the cerebrospinal fluid of patients with central nervous system autoimmune demyelination produce "oligoclonal bands".Q48412765
Rituximab in patients with primary progressive multiple sclerosis: results of a randomized double-blind placebo-controlled multicenter trial.Q48427388
Short-lived plasma blasts are the main B cell effector subset during the course of multiple sclerosisQ48949365
The role of brain barriers in fluid movement in the CNS: is there a 'glymphatic' system?Q50048969
Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis.Q51027456
Immunological memory: contribution of memory B cells expressing costimulatory molecules in the resting state.Q52016419
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectimmunologyQ101929
neuroscienceQ207011
P577publication date2019-03-21
P1433published inJCI insightQ27727187
P1476titleLongitudinally persistent cerebrospinal fluid B cells can resist treatment in multiple sclerosis
P478volume4

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cites work (P2860)
Q92339537Induction of brain-infiltrating T-bet-expressing B cells in multiple sclerosis
Q93062665Single-Cell High-Throughput Technologies in Cerebrospinal Fluid Research and Diagnostics

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