| scholarly article | Q13442814 |
| P50 | author | Stephen Peuchen | Q71675612 |
| P2093 | author name string | J B Clark | |
| G P Davey | |||
| P2860 | cites work | Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor | Q24561804 |
| P433 | issue | 21 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | mitochondrion | Q39572 |
| neurodegeneration | Q1755122 | ||
| P304 | page(s) | 12753-12757 | |
| P577 | publication date | 1998-05-01 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Energy thresholds in brain mitochondria. Potential involvement in neurodegeneration | |
| P478 | volume | 273 |
| Q51974526 | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced complex I inhibition is reversed by disulfide reductant, dithiothreitol in mouse brain. |
| Q48251144 | 4-Hydroxy-2(E)-nonenal inhibits CNS mitochondrial respiration at multiple sites |
| Q34058380 | A mild impairment of mitochondrial electron transport has sex-specific effects on lifespan and aging in mice |
| Q36724691 | AIF, reactive oxygen species, and neurodegeneration: a "complex" problem |
| Q40461220 | Acidosis during reoxygenation has an early detrimental effect on neuronal metabolic activity. |
| Q45306888 | Age-dependent changes in nitric oxide synthase activity and protein expression in striata of mice transgenic for the Huntington's disease mutation |
| Q33709605 | Age-related changes in mitochondrial respiration and oxidative damage in the cerebral cortex of the Fischer 344 rat. |
| Q34147870 | Age-related mitochondrial changes after traumatic brain injury |
| Q39329410 | Alterations in bioenergetic function induced by Parkinson's disease mimetic compounds: lack of correlation with superoxide generation |
| Q35090105 | Altered zinc transport disrupts mitochondrial protein processing/import in fragile X-associated tremor/ataxia syndrome |
| Q50032095 | An investigation into closed-loop treatment of neurological disorders based on sensing mitochondrial dysfunction |
| Q36502980 | Analysis of regional brain mitochondrial bioenergetics and susceptibility to mitochondrial inhibition utilizing a microplate based system |
| Q37411623 | Antagonism of nitric oxide toward the inhibition of cytochrome c oxidase by carbon monoxide and cyanide |
| Q44189183 | Antioxidant properties of MDL and MMDL, two nicergoline metabolites, during chronic administration of haloperidol |
| Q44175709 | Apolipoprotein E deficiency promotes increased oxidative stress and compensatory increases in antioxidants in brain tissue |
| Q39625718 | Apolipoprotein E4 domain interaction mediates detrimental effects on mitochondria and is a potential therapeutic target for Alzheimer disease |
| Q43623410 | Assessing functional integrity of mitochondria in vitro and in vivo |
| Q90632651 | Assessment of Mitochondrial Dysfunction in Experimental Autoimmune Encephalomyelitis (EAE) Models of Multiple Sclerosis |
| Q45323360 | Association of a missense nucleotide polymorphism in the MT-ND2 gene with mitochondrial reactive oxygen species production in the Tibet chicken embryo incubated in normoxia or simulated hypoxia |
| Q33836239 | Bioenergetics in Huntington's disease |
| Q47265377 | Biological Implications of Differential Expression of Mitochondrial-Shaping Proteins in Parkinson's Disease. |
| Q22252362 | Brain cholinesterases: II. The molecular and cellular basis of Alzheimer's disease |
| Q41626712 | Bypassing the compromised mitochondrial electron transport with methylene blue alleviates efavirenz/isoniazid-induced oxidant stress and mitochondria-mediated cell death in mouse hepatocytes |
| Q42810724 | Cellular Stress Responses, Mitostress and Carnitine Insufficiencies as Critical Determinants in Aging and Neurodegenerative Disorders: Role of Hormesis and Vitagenes |
| Q37001813 | Cerebral mitochondrial metabolism in early Parkinson's disease |
| Q43145621 | Cerebrospinal fluid ATP metabolites in multiple sclerosis |
| Q46519868 | Characteristics of alpha-glycerophosphate-evoked H2O2 generation in brain mitochondria |
| Q47558662 | Chronic dietary creatine enhances hippocampal-dependent spatial memory, bioenergetics, and levels of plasticity-related proteins associated with NF-κB. |
| Q37108109 | Clearing the brain's cobwebs: the role of autophagy in neuroprotection |
| Q90043232 | Complex I Controls Mitochondrial and Plasma Membrane Potentials in Nerve Terminals |
| Q37152829 | Complex I is rate-limiting for oxygen consumption in the nerve terminal |
| Q42123867 | Complex I-mediated reactive oxygen species generation: modulation by cytochrome c and NAD(P)+ oxidation-reduction state. |
| Q37854101 | Connectivity between mitochondrial functions and psychiatric disorders |
| Q44740371 | Contribution of the phosphorylable complex I in the growth phase-dependent respiration of C6 glioma cells in vitro |
| Q42732590 | Curcumin attenuates aluminum-induced oxidative stress and mitochondrial dysfunction in rat brain |
| Q34240503 | Cytochrome c oxidase loses catalytic activity and structural integrity during the aging process in Drosophila melanogaster |
| Q43115232 | Cytochrome c redox state influences the binding and release of cytochrome c in model membranes and in brain mitochondria |
| Q48125319 | Decline in cytochrome c oxidase activity in rat-brain mitochondria with aging. Role of peroxidized cardiolipin and beneficial effect of melatonin |
| Q44270676 | Delayed hypothermia prevents decreases in N-acetylaspartate and reduced glutathione in the cerebral cortex of the neonatal pig following transient hypoxia-ischaemia. |
| Q48198160 | Differences in the activation of the mitochondrial permeability transition among brain regions in the rat correlate with selective vulnerability |
| Q33978880 | Differential effects of antiretroviral nucleoside analogs on mitochondrial function in HepG2 cells |
| Q36494335 | Differential mitochondrial protein expression profiling in neurodegenerative diseases |
| Q35906775 | Dynamics of subcellular proteomes during brain development |
| Q47074213 | Early developmental pathology due to cytochrome c oxidase deficiency is revealed by a new zebrafish model |
| Q38880828 | Efavirenz alters mitochondrial respiratory function in cultured neuron and glial cell lines |
| Q28344441 | Effect of 'binary mitochondrial heteroplasmy' on respiration and ATP synthesis: implications for mitochondrial diseases |
| Q43639267 | Effect of antioxidants on L-glutamate and N-methyl-4-phenylpyridinium ion induced-neurotoxicity in PC12 cells |
| Q53445968 | Effect of chronic treatment of haloperidol on the rat liver: a stereological and histopathological study. |
| Q48494914 | Effects of partial inhibition of respiratory complex I on H2O 2 production by isolated brain mitochondria in different respiratory states |
| Q48591601 | Elevated oxidative stress and decreased antioxidant function in the human hippocampus and frontal cortex with increasing age: implications for neurodegeneration in Alzheimer's disease |
| Q34995130 | Energetics and oxidative stress in synaptic plasticity and neurodegenerative disorders |
| Q44884784 | Energy failure in astrocytes increases the vulnerability of neurons to spreading depression |
| Q28389950 | Energy failure: does it contribute to neurodegeneration? |
| Q46412503 | Enhancement of cyanide-induced mitochondrial dysfunction and cortical cell necrosis by uncoupling protein-2. |
| Q43248182 | Evidence of reactive oxygen species-mediated damage to mitochondrial DNA in children with typical autism |
| Q35678101 | Expression of oxidative phosphorylation components in mitochondria of long-living Ames dwarf mice |
| Q34477829 | Expression profiles of mitochondrial genes in the frontal cortex and the caudate nucleus of developing humans and mice selectively bred for high and low fear |
| Q35068082 | Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders |
| Q33680041 | Ginkgo biloba extract ameliorates oxidative phosphorylation performance and rescues abeta-induced failure |
| Q28576791 | Ginkgo biloba extracts EGb 761 and bilobalide increase NADH dehydrogenase mRNA level and mitochondrial respiratory control ratio in PC12 cells |
| Q37865165 | Glucose in platelet additive solutions: to add or not to add? |
| Q34816461 | Glutathione, iron and Parkinson's disease |
| Q35203821 | High-level inhibition of mitochondrial complexes III and IV is required to increase glutamate release from the nerve terminal |
| Q45061851 | Highly selective and prolonged depletion of mitochondrial glutathione in astrocytes markedly increases sensitivity to peroxynitrite. |
| Q32138928 | How understanding the control of energy metabolism can help investigation of mitochondrial dysfunction, regulation and pharmacology |
| Q39318947 | Human neuronal coenzyme Q10 deficiency results in global loss of mitochondrial respiratory chain activity, increased mitochondrial oxidative stress and reversal of ATP synthase activity: implications for pathogenesis and treatment. |
| Q43884183 | Hypothesis: the mitochondrial NO(*) signaling pathway, and the transduction of nitrosative to oxidative cell signals: an alternative function for cytochrome C oxidase |
| Q47797190 | Implications of enzyme deficiencies on mitochondrial energy metabolism and reactive oxygen species formation of neurons involved in rotenone-induced Parkinson's disease: a model-based analysis |
| Q42808298 | In brain mitochondria the branched-chain fatty acid phytanic acid impairs energy transduction and sensitizes for permeability transition |
| Q34062684 | In vivo control of respiration by cytochrome c oxidase in human cells |
| Q34308036 | Initiation of neuronal damage by complex I deficiency and oxidative stress in Parkinson's disease. |
| Q33300939 | Interaction of cyanide and nitric oxide with cytochrome c oxidase: implications for acute cyanide toxicity |
| Q34868333 | Intrinsic bioenergetic properties and stress sensitivity of dopaminergic synaptosomes |
| Q37152258 | Investigating complex I deficiency in Purkinje cells and synapses in patients with mitochondrial disease |
| Q35668405 | Is defective electron transport at the hub of aging? |
| Q34073840 | Long-lasting inhibition of presynaptic metabolism and neurotransmitter release by protein S-nitrosylation |
| Q24299953 | Loss of m-AAA protease in mitochondria causes complex I deficiency and increased sensitivity to oxidative stress in hereditary spastic paraplegia |
| Q38070400 | MPTP mouse models of Parkinson's disease: an update |
| Q35045143 | Mechanisms of cell death pathway activation following drug-induced inhibition of mitochondrial complex I. |
| Q33954265 | Mechanisms of pathogenesis in drug hepatotoxicity putting the stress on mitochondria |
| Q28507748 | Metabolic consequences of the cytochrome c oxidase deficiency in brain of copper-deficient Mo(vbr) mice |
| Q24651159 | Metabolic control analysis in a cellular model of elevated MAO-B: relevance to Parkinson's disease |
| Q44509587 | Method for measuring ATP production in isolated mitochondria: ATP production in brain and liver mitochondria of Fischer-344 rats with age and caloric restriction |
| Q47853116 | Mitochondria at the neuronal presynapse in health and disease. |
| Q43516555 | Mitochondria deficient in complex I activity are depolarized by hydrogen peroxide in nerve terminals: relevance to Parkinson's disease |
| Q38678063 | Mitochondrial Mutations in Cardiac Disorders |
| Q45306770 | Mitochondrial NAD+-linked State 3 respiration and complex-I activity are compromised in the cerebral cortex of 3-nitropropionic acid-induced rat model of Huntington's disease. |
| Q42391404 | Mitochondrial alpha-synuclein accumulation impairs complex I function in dopaminergic neurons and results in increased mitophagy in vivo |
| Q26824090 | Mitochondrial biology and Parkinson's disease |
| Q46104140 | Mitochondrial calcium transport and mitochondrial dysfunction after global brain ischemia in rat hippocampus. |
| Q48933219 | Mitochondrial complex I subunits are altered in rats with neonatal ventral hippocampal damage but not in rats exposed to oxygen restriction at neonatal age. |
| Q35707180 | Mitochondrial disease: a historical, biochemical, and London perspective |
| Q37558748 | Mitochondrial dysfunction in autism |
| Q30995022 | Mitochondrial dysfunction in bipolar disorder: evidence from magnetic resonance spectroscopy research |
| Q34801664 | Mitochondrial function and dysfunction in the cell: its relevance to aging and aging-related disease |
| Q35707222 | Mitochondrial function in apoptotic neuronal cell death |
| Q34344644 | Mitochondrial involvement in brain function and dysfunction: relevance to aging, neurodegenerative disorders and longevity |
| Q24537310 | Mitochondrial lipid abnormality and electron transport chain impairment in mice lacking alpha-synuclein |
| Q46189389 | Mitochondrial remodeling in the liver following chronic alcohol feeding to rats |
| Q45297269 | Mitochondrial respiration and ATP production are significantly impaired in striatal cells expressing mutant huntingtin |
| Q48127824 | Mitochondrial respiratory function and cell death in focal cerebral ischemia |
| Q35017647 | Mitochondrial threshold effects. |
| Q77993742 | Mutation of the mitochrondrially encoded ATPase 6 gene modeled in the ATP synthase of Escherichia coli |
| Q48451343 | N-Methyl, N-propynyl-2-phenylethylamine (MPPE), a Selegiline Analog, Attenuates MPTP-induced Dopaminergic Toxicity with Guaranteed Behavioral Safety: Involvement of Inhibitions of Mitochondrial Oxidative Burdens and p53 Gene-elicited Pro-apoptotic C |
| Q34074236 | NO synthase and NO-dependent signal pathways in brain aging and neurodegenerative disorders: the role of oxidant/antioxidant balance. |
| Q33383204 | Neuroanatomical pattern of mitochondrial complex I pathology varies between schizophrenia, bipolar disorder and major depression |
| Q34733383 | Neuroprotective effect of EGb761® and low-dose whole-body γ-irradiation in a rat model of Parkinson's disease |
| Q35051331 | Nitric oxide-induced mitochondrial dysfunction: implications for neurodegeneration |
| Q35789018 | Nonselenium glutathione peroxidase in human brain : elevated levels in Parkinson's disease and dementia with lewy bodies |
| Q35038212 | Normal brain ageing: models and mechanisms |
| Q24307861 | Oxidative damage to mitochondrial complex I due to peroxynitrite: identification of reactive tyrosines by mass spectrometry |
| Q54596363 | PPARalpha-mediated upregulation of uncoupling protein-2 switches cyanide-induced apoptosis to necrosis in primary cortical cells. |
| Q26746899 | Parkinson's Disease: The Mitochondria-Iron Link |
| Q29547424 | Parkinson's disease: mechanisms and models |
| Q46326704 | Physiopathological effects of the NO donor 3-morpholinosydnonimine on rat cortical synaptosomes |
| Q44214157 | Pre-treatment with R-lipoic acid alleviates the effects of GSH depletion in PC12 cells: implications for Parkinson's disease therapy |
| Q45973362 | Protective effect of curcuminoids on age-related mitochondrial impairment in female Wistar rat brain. |
| Q32062163 | Protein thiol oxidation by haloperidol results in inhibition of mitochondrial complex I in brain regions: comparison with atypical antipsychotics |
| Q28579972 | Proteomic and metabolomic analyses of mitochondrial complex I-deficient mouse model generated by spontaneous B2 short interspersed nuclear element (SINE) insertion into NADH dehydrogenase (ubiquinone) Fe-S protein 4 (Ndufs4) gene |
| Q33588989 | Quantitative proteomics of synaptic and nonsynaptic mitochondria: insights for synaptic mitochondrial vulnerability. |
| Q37417088 | Reactive oxygen species regulation by AIF- and complex I-depleted brain mitochondria. |
| Q33914038 | Repositioning chlorpromazine for treating chemoresistant glioma through the inhibition of cytochrome c oxidase bearing the COX4-1 regulatory subunit |
| Q43975363 | Seizure-dependent modulation of mitochondrial oxidative phosphorylation in rat hippocampus |
| Q28576367 | Selective binding of nuclear alpha-synuclein to the PGC1alpha promoter under conditions of oxidative stress may contribute to losses in mitochondrial function: implications for Parkinson's disease |
| Q35634060 | Selective defect of in vivo glycolysis in early Huntington's disease striatum |
| Q37984548 | Selective vulnerability of synaptic signaling and metabolism to nitrosative stress |
| Q44005791 | Sequence analysis of two nuclear encoded subunits (10 and 51 kDa) of mitochondrial complex I in Parkinson disease |
| Q30586804 | Socially responsive effects of brain oxidative metabolism on aggression |
| Q36691223 | Some observations upon biochemical causes of ataxia and a new disease entity ubiquinone, CoQ10 deficiency |
| Q33296977 | Sp1 expression is disrupted in schizophrenia; a possible mechanism for the abnormal expression of mitochondrial complex I genes, NDUFV1 and NDUFV2 |
| Q40379655 | Structural determinants of schisandrin B which enhance mitochondrial functional ability and glutathione status as well as heat shock protein expression in rat hearts and H9c2 cells |
| Q35856269 | Sustained expression of PGC-1α in the rat nigrostriatal system selectively impairs dopaminergic function. |
| Q35628591 | Synapses and Sisyphus: life without paraplegin |
| Q50222849 | Targeting mitochondria with methylene blue protects mice against acetaminophen-induced liver injury |
| Q35574384 | Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice. |
| Q92890389 | The Genomic Origins of Small Mitochondrial RNAs: Are They Transcribed by the Mitochondrial DNA or by Mitochondrial Pseudogenes within the Nucleus (NUMTs)? |
| Q28220024 | The NDUFS4 nuclear gene of complex I of mitochondria and the cAMP cascade |
| Q73713859 | The changing face of mitochondrial research |
| Q28072937 | The chicken or the egg: mitochondrial dysfunction as a cause or consequence of toxicity in Huntington's disease |
| Q37588978 | The energy-redox axis in aging and age-related neurodegeneration |
| Q48136460 | The expression of several mitochondrial and nuclear genes encoding the subunits of electron transport chain enzyme complexes, cytochrome c oxidase, and NADH dehydrogenase, in different brain regions in Alzheimer's disease |
| Q34765899 | The human postsynaptic density shares conserved elements with proteomes of unicellular eukaryotes and prokaryotes |
| Q34612231 | The interplay between mitochondrial complex I, dopamine and Sp1 in schizophrenia |
| Q28304995 | The ketogenic diet component decanoic acid increases mitochondrial citrate synthase and complex I activity in neuronal cells |
| Q36853449 | The pleiotropic effects of decanoic acid treatment on mitochondrial function in fibroblasts from patients with complex I deficient Leigh syndrome |
| Q57086168 | The use of lymphocytes to screen for oxidative phosphorylation disorders |
| Q42120615 | Therapeutic effects of hydrogen in animal models of Parkinson's disease. |
| Q24648251 | Thiamine triphosphate synthesis in rat brain occurs in mitochondria and is coupled to the respiratory chain |
| Q44156159 | Thioltransferase (glutaredoxin) mediates recovery of motor neurons from excitotoxic mitochondrial injury. |
| Q42996199 | Tissue variation in the control of oxidative phosphorylation: implication for mitochondrial diseases |
| Q47442924 | Towards an Understanding of Energy Impairment in Huntington's Disease Brain |
| Q36957020 | Toxicity of the flame-retardant BDE-49 on brain mitochondria and neuronal progenitor striatal cells enhanced by a PTEN-deficient background |
| Q38836746 | Tristetraprolin inhibits mitochondrial function through suppression of α-Synuclein expression in cancer cells |
| Q32139005 | What do mitochondrial diseases teach us about normal mitochondrial functions...that we already knew: threshold expression of mitochondrial defects. |
| Q47202550 | α-Synuclein protects neurons from apoptosis downstream of free-radical production through modulation of the MAPK signalling pathway. |
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