Stat3 controls lysosomal-mediated cell death in vivo

scientific article published on 20 February 2011

Stat3 controls lysosomal-mediated cell death in vivo is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/NCB2171
P698PubMed publication ID21336304
P5875ResearchGate publication ID49850523

P50authorValeria PoliQ35703792
Richard ClarksonQ43081627
Anna D StaniszewskaQ52430540
Peter A KreuzalerQ63762484
P2093author name stringWenjing Li
Richard A Flavell
Christine J Watson
James Turkson
Nader Omidvar
Blandine Kedjouar
P2860cites workFas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector moleculeQ24290576
An intracellular serpin regulates necrosis by inhibiting the induction and sequelae of lysosomal injuryQ24294713
Signal transducers and activators of transcription 3 (STAT3) inhibits transcription of the inducible nitric oxide synthase gene by interacting with nuclear factor kappaBQ24534564
Gene expression profiling of mammary gland development reveals putative roles for death receptors and immune mediators in post-lactational regressionQ24794250
Multiple pathways of TWEAK-induced cell deathQ28214614
Sphingosine-induced apoptosis is dependent on lysosomal proteasesQ28360876
Cathepsin B knockout mice are resistant to tumor necrosis factor-alpha-mediated hepatocyte apoptosis and liver injury: implications for therapeutic applicationsQ28365734
Caspases 3 and 7: key mediators of mitochondrial events of apoptosisQ28588439
STATs in cancer inflammation and immunity: a leading role for STAT3Q29547203
IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancerQ29614594
Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factorQ30481000
The murine Spi-2 proteinase inhibitor locus: a multigene family with a hypervariable reactive site domain.Q30885505
A dual role for oncostatin M signaling in the differentiation and death of mammary epithelial cells in vivoQ33642635
Implication of cysteine proteases calpain, cathepsin and caspase in ischemic neuronal death of primatesQ33935231
Essential role of STAT3 in the control of the acute-phase response as revealed by inducible gene inactivation [correction of activation] in the liverQ33967216
A nonapoptotic cell death process, entosis, that occurs by cell-in-cell invasion.Q34008429
Two distinct phases of apoptosis in mammary gland involution: proteinase-independent and -dependent pathways.Q34103424
Decreased apoptosis in the brain and premature lethality in CPP32-deficient miceQ34408475
Identification of a molecular signaling network that regulates a cellular necrotic cell death pathwayQ34910947
Suppression of epithelial apoptosis and delayed mammary gland involution in mice with a conditional knockout of Stat3.Q35207498
Caspase-independent cell death?Q35743103
Lysosomes in cell deathQ35743134
Lysosomes and autophagy in cell death controlQ36292872
Cysteine cathepsins: multifunctional enzymes in cancerQ36600996
The beginning of the end: death signaling in early involutionQ36752770
NF-kappaB protects from the lysosomal pathway of cell death.Q39927881
IKKbeta/2 induces TWEAK and apoptosis in mammary epithelial cellsQ40300890
NF-kappaB inhibits apoptosis in murine mammary epitheliaQ40884614
Sensitization to the lysosomal cell death pathway by oncogene-induced down-regulation of lysosome-associated membrane proteins 1 and 2.Q42809574
A dual, non-redundant, role for LIF as a regulator of development and STAT3-mediated cell death in mammary glandQ44480678
Serine protease inhibitor 2A is a protective factor for memory T cell developmentQ45018416
Interaction of the baculovirus anti-apoptotic protein p35 with caspases. Specificity, kinetics, and characterization of the caspase/p35 complex.Q46026102
Eradication of glioblastoma, and breast and colon carcinoma xenografts by Hsp70 depletion.Q48420309
The IL-4/IL-13/Stat6 signalling pathway promotes luminal mammary epithelial cell developmentQ48543461
Transforming growth factor beta3 induces cell death during the first stage of mammary gland involution.Q52167469
Efficient BLG-Cre mediated gene deletion in the mammary gland.Q52181362
Deficiency in caspase-9 or caspase-3 induces compensatory caspase activationQ70607132
Capillary surface area is reduced and tissue thickness from capillaries to myocytes is increased in the left ventricle of streptozotocin-diabetic ratsQ72348996
Mouse mammary gland involution is associated with cytochrome c release and caspase activationQ74014346
Reduced tumour cell proliferation and delayed development of high-grade mammary carcinomas in cathepsin B-deficient miceQ80883582
C/EBPdelta is a crucial regulator of pro-apoptotic gene expression during mammary gland involutionQ81279579
Mammary gland involution is associated with rapid down regulation of major mammary Ca2+-ATPasesQ82564839
Nitration of cathepsin D enhances its proteolytic activity during mammary gland remodelling after lactationQ83151521
P433issue3
P921main subjectcell deathQ2383867
P304page(s)303-309
P577publication date2011-02-20
P1433published inNature Cell BiologyQ1574111
P1476titleStat3 controls lysosomal-mediated cell death in vivo
P478volume13

Reverse relations

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