| scholarly article | Q13442814 |
| P2093 | author name string | Irving M Shapiro | |
| Makarand V Risbud | |||
| Zariel I Johnson | |||
| P2860 | cites work | Bridging the NFAT and NF-kappaB families: NFAT5 dimerization regulates cytokine gene transcription in response to osmotic stress | Q24291525 |
| NFAT5 binds to the TNF promoter distinctly from NFATp, c, 3 and 4, and activates TNF transcription during hypertonic stress alone | Q24816996 | ||
| Role of cytokines in intervertebral disc degeneration: pain and disc content | Q27001658 | ||
| TonEBP stimulates multiple cellular pathways for adaptation to hypertonic stress: organic osmolyte-dependent and -independent pathways | Q28302484 | ||
| Hypoxia activates MAPK activity in rat nucleus pulposus cells: regulation of integrin expression and cell survival | Q28576901 | ||
| Osmolarity and intracellular calcium regulate aquaporin2 expression through TonEBP in nucleus pulposus cells of the intervertebral disc | Q28582270 | ||
| Osmoprotective transcription factor NFAT5/TonEBP modulates nuclear factor-kappaB activity | Q30496797 | ||
| Changes in water content of intervertebral discs and paravertebral muscles before and after bed rest | Q33408878 | ||
| TonEBP/OREBP is a regulator of nucleus pulposus cell function and survival in the intervertebral disc | Q83986148 | ||
| The intervertebral disc contains intrinsic circadian clocks that are regulated by age and cytokines and linked to degeneration | Q33731721 | ||
| Structure and function of aggrecan | Q34122868 | ||
| T1ρ magnetic resonance imaging and discography pressure as novel biomarkers for disc degeneration and low back pain | Q34167386 | ||
| Tonicity-responsive microRNAs contribute to the maximal induction of osmoregulatory transcription factor OREBP in response to high-NaCl hypertonicity | Q34513790 | ||
| Leptin induces cyclin D1 expression and proliferation of human nucleus pulposus cells via JAK/STAT, PI3K/Akt and MEK/ERK pathways | Q34541732 | ||
| PI3K/AKT regulates aggrecan gene expression by modulating Sox9 expression and activity in nucleus pulposus cells of the intervertebral disc | Q34589291 | ||
| Monocyte chemotactic protein 1 (MCP-1) modulates pro-survival signaling to promote progression of head and neck squamous cell carcinoma | Q35106460 | ||
| BMP-2 and TGF-beta stimulate expression of beta1,3-glucuronosyl transferase 1 (GlcAT-1) in nucleus pulposus cells through AP1, TonEBP, and Sp1: role of MAPKs | Q35157807 | ||
| Extracellular osmolarity regulates matrix homeostasis in the intervertebral disc and articular cartilage: evolving role of TonEBP | Q35323760 | ||
| Hyperosmolarity invokes distinct anti-inflammatory mechanisms in pulmonary epithelial cells: evidence from signaling and transcription layers | Q35494634 | ||
| Monocyte chemotactic protein-1 promotes the proliferation and invasion of osteosarcoma cells and upregulates the expression of AKT | Q35628416 | ||
| Gene expression induced by Toll-like receptors in macrophages requires the transcription factor NFAT5 | Q35760842 | ||
| CCL2/CCR2 chemokine signaling coordinates survival and motility of breast cancer cells through Smad3 protein- and p42/44 mitogen-activated protein kinase (MAPK)-dependent mechanisms | Q36332973 | ||
| Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon gamma and lipopolysaccharide | Q36609461 | ||
| Fat-specific protein 27 modulates nuclear factor of activated T cells 5 and the cellular response to stress | Q36744115 | ||
| LPS-induced NFκB enhanceosome requires TonEBP/NFAT5 without DNA binding | Q36841546 | ||
| NFAT5/TonEBP mutant mice define osmotic stress as a critical feature of the lymphoid microenvironment | Q36986637 | ||
| Reactive oxygen species regulate context-dependent inhibition of NFAT5 target genes | Q37064902 | ||
| A key regulatory role for Vav1 in controlling lipopolysaccharide endotoxemia via macrophage-derived IL-6. | Q37633249 | ||
| The cytokine and chemokine expression profile of nucleus pulposus cells: implications for degeneration and regeneration of the intervertebral disc. | Q37691242 | ||
| Biomechanics of intervertebral disk degeneration | Q37938106 | ||
| Regulation of the hyperosmotic induction of aquaporin 5 and VEGF in retinal pigment epithelial cells: involvement of NFAT5 | Q38299744 | ||
| A c-Rel subdomain responsible for enhanced DNA-binding affinity and selective gene activation. | Q38320987 | ||
| Prolyl hydroxylase EGLN3 regulates skeletal myoblast differentiation through an NF-kappaB-dependent pathway | Q39615856 | ||
| The expression of aquaporin-1 in the medulla of the kidney is dependent on the transcription factor associated with hypertonicity, TonEBP. | Q39678716 | ||
| Hypertonicity-induced expression of monocyte chemoattractant protein-1 through a novel cis-acting element and MAPK signaling pathways | Q39718833 | ||
| Expression of taurine transporter is regulated through the TonE (tonicity-responsive element)/TonEBP (TonE-binding protein) pathway and contributes to cytoprotection in HepG2 cells | Q40556250 | ||
| Circadian factors BMAL1 and RORα control HIF-1α transcriptional activity in nucleus pulposus cells: implications in maintenance of intervertebral disc health | Q41133336 | ||
| Regulation of gene expression by hypertonicity | Q41387971 | ||
| Tonicity-dependent induction of Sgk1 expression has a potential role in dehydration-induced natriuresis in rodents. | Q42110630 | ||
| Physiological tonicity improves human chondrogenic marker expression through nuclear factor of activated T-cells 5 in vitro | Q42262285 | ||
| Activation of TonEBP by calcium controls {beta}1,3-glucuronosyltransferase-I expression, a key regulator of glycosaminoglycan synthesis in cells of the intervertebral disc | Q42868510 | ||
| A clinical study of degenerative spondylolisthesis. Radiographic analysis and choice of treatment | Q45785692 | ||
| Nucleus pulposus cells upregulate PI3K/Akt and MEK/ERK signaling pathways under hypoxic conditions and resist apoptosis induced by serum withdrawal | Q46440724 | ||
| Nitric oxide regulation system in degenerative lumbar disease | Q46666894 | ||
| Nucleus pulposus cells express HIF-1 alpha under normoxic culture conditions: a metabolic adaptation to the intervertebral disc microenvironment | Q46891204 | ||
| Glycosaminoglycan chemical exchange saturation transfer of lumbar intervertebral discs in patients with spondyloarthritis. | Q50950066 | ||
| Cytokine profile in degenerated painful intervertebral disc: variability with respect to duration of symptoms and type of disease. | Q53148502 | ||
| Quantitative analysis of types I and II collagens in human intervertebral discs at various ages | Q67021472 | ||
| MEK/ERK signaling controls osmoregulation of nucleus pulposus cells of the intervertebral disc by transactivation of TonEBP/OREBP | Q79981860 | ||
| P4510 | describes a project that uses | ImageQuant | Q112270642 |
| P433 | issue | 52 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 26686-26697 | |
| P577 | publication date | 2016-11-08 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | RNA Sequencing Reveals a Role of TonEBP Transcription Factor in Regulation of Pro-inflammatory Genes in Response to Hyperosmolarity in Healthy Nucleus Pulposus Cells: A HOMEOSTATIC RESPONSE? | |
| P478 | volume | 291 |
| Q47936637 | Bicarbonate Recycling by HIF-1-Dependent Carbonic Anhydrase Isoforms 9 and 12 Is Critical in Maintaining Intracellular pH and Viability of Nucleus Pulposus Cells |
| Q88487617 | COX-2 expression mediated by calcium-TonEBP signaling axis under hyperosmotic conditions serves osmoprotective function in nucleus pulposus cells |
| Q55052402 | Expression of Carbonic Anhydrase III, a Nucleus Pulposus Phenotypic Marker, is Hypoxia-responsive and Confers Protection from Oxidative Stress-induced Cell Death. |
| Q87947877 | Glycosaminoglycan synthesis in the nucleus pulposus: Dysregulation and the pathogenesis of disc degeneration |
| Q33867011 | Lack of evidence for involvement of TonEBP and hyperosmotic stimulus in induction of autophagy in the nucleus pulposus |
| Q91846231 | NFAT5/TonEBP controls early acquisition of notochord phenotypic markers, collagen composition, and sonic hedgehog signaling during mouse intervertebral disc embryogenesis |
| Q90999547 | Nucleus pulposus primary cilia alter their length in response to changes in extracellular osmolarity but do not control TonEBP-mediated osmoregulation |
| Q47904196 | TNF-α promotes nuclear enrichment of the transcription factor TonEBP/NFAT5 to selectively control inflammatory but not osmoregulatory responses in nucleus pulposus cells |
| Q58584194 | Transcriptome analysis identifies activated signaling pathways and regulated ABC transporters and solute carriers after hyperosmotic stress in renal MDCK I cells |
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