| scholarly article | Q13442814 |
| P50 | author | Xi Chen | Q58120162 |
| P2093 | author name string | Xia Liu | |
| Yang Lu | |||
| Xia Lin | |||
| Xin-Hua Feng | |||
| John B Patterson | |||
| Zheng Sun | |||
| Yiwen Chen | |||
| Feng Li | |||
| Yi Jiang | |||
| Frank Sicheri | |||
| Yu Xiang | |||
| Qing Shi | |||
| Haifa Shen | |||
| Leng Han | |||
| Na Zhao | |||
| Jeffrey M Rosen | |||
| Bo Yuan | |||
| Yunfei Wang | |||
| Jin Cao | |||
| Mingzhou Li | |||
| Qianzi Tang | |||
| Michael T Lewis | |||
| Wen Bu | |||
| Nagireddy Putluri | |||
| Lacey E Dobrolecki | |||
| Haoqiang Ying | |||
| Qingping Zeng | |||
| Longyong Xu | |||
| Yingyun Gong | |||
| Xiaoran Wang | |||
| Xiangdong Lv | |||
| Sean M Hartig | |||
| Manisha Talukdar | |||
| Benny Abraham Kaipparettu | |||
| Dorothy Z Hu | |||
| P2860 | cites work | Pharmacological brake-release of mRNA translation enhances cognitive memory | Q21128794 |
| XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor | Q24292102 | ||
| Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development | Q24292104 | ||
| Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7 | Q24337643 | ||
| The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule | Q24596804 | ||
| Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma | Q24598483 | ||
| Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma | Q24600346 | ||
| The tumor lysis syndrome | Q24605151 | ||
| Comprehensive molecular portraits of human breast tumours | Q24630844 | ||
| Endoplasmic reticulum stress in malignancy | Q27006434 | ||
| Structure and mechanism of action of the hydroxy–aryl–aldehyde class of IRE1 endoribonuclease inhibitors | Q27640568 | ||
| Structure of the Dual Enzyme Ire1 Reveals the Basis for Catalysis and Regulation in Nonconventional RNA Splicing | Q27649529 | ||
| The unfolded protein response signals through high-order assembly of Ire1 | Q27653139 | ||
| Inhibition of ER stress-associated IRE-1/XBP-1 pathway reduces leukemic cell survival | Q38996766 | ||
| Epithelial-to-mesenchymal transition activates PERK-eIF2α and sensitizes cells to endoplasmic reticulum stress | Q39007267 | ||
| Elements of cancer immunity and the cancer-immune set point | Q39094764 | ||
| IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates. | Q39814866 | ||
| Ceapins are a new class of unfolded protein response inhibitors, selectively targeting the ATF6α branch. | Q42115604 | ||
| Characterization of a novel PERK kinase inhibitor with antitumor and antiangiogenic activity | Q46379013 | ||
| IRE1α RNase-dependent lipid homeostasis promotes survival in Myc-transformed cancers. | Q48519557 | ||
| A mammary-specific model demonstrates the role of the p53 tumor suppressor gene in tumor development | Q61911906 | ||
| Differential contributions of ATF6 and XBP1 to the activation of endoplasmic reticulum stress-responsive cis-acting elements ERSE, UPRE and ERSE-II | Q81144490 | ||
| Dimeric Structure of Pseudokinase RNase L Bound to 2-5A Reveals a Basis for Interferon-Induced Antiviral Activity | Q27681451 | ||
| Signal integration in the endoplasmic reticulum unfolded protein response | Q27860577 | ||
| A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus | Q27930818 | ||
| The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response | Q27933479 | ||
| Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase | Q27938837 | ||
| The Myc/Max/Mad network and the transcriptional control of cell behavior | Q28141143 | ||
| IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA | Q28214814 | ||
| A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis | Q28255073 | ||
| Expression cloning of 2-5A-dependent RNAase: A uniquely regulated mediator of interferon action | Q28297833 | ||
| ER stress regulates myeloid-derived suppressor cell fate through TRAIL-R-mediated apoptosis | Q28386923 | ||
| ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis | Q28389316 | ||
| Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
| Integration of external signaling pathways with the core transcriptional network in embryonic stem cells | Q29547179 | ||
| The unfolded protein response: from stress pathway to homeostatic regulation | Q29547396 | ||
| Principles of cancer therapy: oncogene and non-oncogene addiction | Q29616779 | ||
| MYC on the path to cancer | Q29619979 | ||
| Nonlinear model-based estimates of IC(50) for studies involving continuous therapeutic dose-response data | Q31160584 | ||
| A Phos-tag-based approach reveals the extent of physiological endoplasmic reticulum stress | Q33641274 | ||
| Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts | Q33742688 | ||
| XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway | Q33926690 | ||
| Transcriptional amplification in tumor cells with elevated c-Myc. | Q34302542 | ||
| The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation | Q34835596 | ||
| Sec63 and Xbp1 regulate IRE1α activity and polycystic disease severity | Q35719978 | ||
| Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cells | Q35779268 | ||
| MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibition | Q35894198 | ||
| Comparing computer-generated and pathologist-generated tumour segmentations for immunohistochemical scoring of breast tissue microarrays. | Q36295039 | ||
| ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth | Q36497999 | ||
| SIRT6 Suppresses Pancreatic Cancer through Control of Lin28b | Q36968417 | ||
| A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models | Q37067545 | ||
| Subcellular localization of glycogen synthase kinase 3beta controls embryonic stem cell self-renewal | Q37145406 | ||
| An easy and efficient inducible CRISPR/Cas9 platform with improved specificity for multiple gene targeting | Q37401076 | ||
| Triple-negative breast cancer: disease entity or title of convenience? | Q37793824 | ||
| The impact of the endoplasmic reticulum protein-folding environment on cancer development | Q38241996 | ||
| Druggable sensors of the unfolded protein response | Q38261088 | ||
| Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. | Q38311676 | ||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P1104 | number of pages | 17 | |
| P304 | page(s) | 1283-1299 | |
| P577 | publication date | 2018-02-26 | |
| P1433 | published in | Journal of Clinical Investigation | Q3186904 |
| P1476 | title | Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer. | |
| P478 | volume | 128 |
| Q55357800 | A New Role for Estrogen Receptor α in Cell Proliferation and Cancer: Activating the Anticipatory Unfolded Protein Response. |
| Q98778664 | Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma |
| Q64283441 | Binding to an Unusual Inactive Kinase Conformation by Highly Selective Inhibitors of Inositol-Requiring Enzyme 1α Kinase-Endoribonuclease |
| Q92879104 | Development of Personalized Therapeutic Strategies by Targeting Actionable Vulnerabilities in Metastatic and Chemotherapy-Resistant Breast Cancer PDXs |
| Q93155378 | Dual role of Endoplasmic Reticulum Stress-Mediated Unfolded Protein Response Signaling Pathway in Carcinogenesis |
| Q92188856 | ER Stress and the UPR in Shaping Intestinal Tissue Homeostasis and Immunity |
| Q97645837 | Effects of CORO2A on Cell Migration and Proliferation and Its Potential Regulatory Network in Breast Cancer |
| Q89951520 | Endoplasmic Reticulum Stress Signaling in Cancer Cells |
| Q98771144 | Endoplasmic Reticulum Stress in Bone Metastases |
| Q102211135 | Endoplasmic reticulum stress signals in the tumour and its microenvironment |
| Q48519557 | IRE1α RNase-dependent lipid homeostasis promotes survival in Myc-transformed cancers. |
| Q61124479 | IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling |
| Q57577429 | Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy |
| Q58725469 | New Hope for Pancreatic Ductal Adenocarcinoma Treatment Targeting Endoplasmic Reticulum Stress Response: A Systematic Review |
| Q99623519 | Pharmacological Targeting of IRE1 in Cancer |
| Q92003537 | Pharmacological targeting of the unfolded protein response for disease intervention |
| Q99594846 | Protein quality control through endoplasmic reticulum-associated degradation maintains haematopoietic stem cell identity and niche interactions |
| Q89727329 | Targeting the Unfolded Protein Response in Hormone-Regulated Cancers |
| Q92000954 | The IRE1 endoplasmic reticulum stress sensor activates natural killer cell immunity in part by regulating c-Myc |
| Q100725422 | The SUMO pathway in pancreatic cancer: insights and inhibition |
| Q57105740 | The Unfolded Protein Response in Breast Cancer |
| Q57473219 | Therapeutic targeting of cellular stress responses in cancer |
| Q92795478 | Unravel the molecular mechanism of XBP1 in regulating the biology of cancer cells |
Search more.