scholarly article | Q13442814 |
review article | Q7318358 |
P50 | author | Lichan Chen | Q86131120 |
P2093 | author name string | Yan He | |
Dezhong Joshua Liao | |||
Ningzhi Xu | |||
Yanjie Liu | |||
Haiyan Zhou | |||
Chengfu Yuan | |||
P2860 | cites work | Endocrine-induced regression of cancers | Q71988266 |
Uptake of (3H)oestradiol by dimethylbenzanthracene-induced rat mammary tumours regressing spontaneously or after ovariectomy | Q72426489 | ||
Cell cycle basis for the onset and progression of c-Myc-induced, TGFalpha-enhanced mouse mammary gland carcinogenesis | Q73540242 | ||
Carcinoma mammae occurring in a male mouse under continued treatment with oestrin | Q74847962 | ||
Tumors of the breast related to the oestrin hormone | Q78248336 | ||
III. The Effect of Scarlet Red, in Various Combinations, upon the Epitheliation of Granulating Surfaces | Q81274991 | ||
Reviewing Einstein | Q85567507 | ||
A novel imprinted transgene located near a repetitive element that exhibits allelic imbalance in DNA methylation during early development | Q85946060 | ||
Einstein's milestones | Q86877954 | ||
Increasing value and reducing waste in biomedical research | Q88101227 | ||
A survey on data reproducibility in cancer research provides insights into our limited ability to translate findings from the laboratory to the clinic | Q21090756 | ||
Rescuing US biomedical research from its systemic flaws | Q22021994 | ||
Genome engineering using the CRISPR-Cas9 system | Q22122027 | ||
An open investigation of the reproducibility of cancer biology research | Q24273259 | ||
How to make more published research true | Q24288766 | ||
Research efficiency: Perverse incentives | Q24496194 | ||
A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language? | Q24629627 | ||
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology | Q24632651 | ||
Deconstructing stem cell tumorigenicity: a roadmap to safe regenerative medicine | Q24646217 | ||
Conditional mouse models demonstrate oncogene-dependent differences in tumor maintenance and recurrence | Q24803965 | ||
Pseudogenes regulate parental gene expression via ceRNA network | Q26738904 | ||
Is the Efficiency of RNA Silencing Evolutionarily Regulated? | Q26749041 | ||
Learning about the Importance of Mutation Prevention from Curable Cancers and Benign Tumors | Q26766238 | ||
To Know How a Gene Works, We Need to Redefine It First but then, More Importantly, to Let the Cell Itself Decide How to Transcribe and Process Its RNAs | Q26774954 | ||
Weaknesses and Pitfalls of Using Mice and Rats in Cancer Chemoprevention Studies | Q26781102 | ||
Protecting the normal in order to better kill the cancer | Q26801291 | ||
Hypothesis: Artifacts, Including Spurious Chimeric RNAs with a Short Homologous Sequence, Caused by Consecutive Reverse Transcriptions and Endogenous Random Primers | Q26820767 | ||
Measuring and Reducing Off-Target Activities of Programmable Nucleases Including CRISPR-Cas9 | Q27011906 | ||
The multilayered complexity of ceRNA crosstalk and competition | Q27025671 | ||
Stem cells, cancer, and cancer stem cells | Q27860878 | ||
Concise Review: Induced Pluripotent Stem Cells as New Model Systems in Oncology | Q28080945 | ||
Technologies for controlled, local delivery of siRNA | Q28087657 | ||
Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes | Q28343950 | ||
Xmrk, kras and myc transgenic zebrafish liver cancer models share molecular signatures with subsets of human hepatocellular carcinoma | Q28540910 | ||
Necrosis, and then stress induced necrosis-like cell death, but not apoptosis, should be the preferred cell death mode for chemotherapy: clearance of a few misconceptions | Q28652643 | ||
Inducible and repressable oncogene-addicted hepatocellular carcinoma in Tet-on xmrk transgenic zebrafish | Q39711102 | ||
Endocrine-induced regression of cancers | Q39859723 | ||
Hormone dependence in breast cancer | Q39899350 | ||
Evolution of epithelial proliferation induced by scarlet red in the skin of normal and carcinogen-treated rabbits | Q39908993 | ||
ERalpha gene expression in human primary osteoblasts: evidence for the expression of two receptor proteins | Q40765356 | ||
"Science Citation Index Worship" in China. | Q40855622 | ||
Experimental Study of the Pathogenesis of Carcinoma | Q41268564 | ||
Analysis of transcription and estrogen insensitivity in the female mouse after targeted disruption of the estrogen receptor gene | Q41275521 | ||
siPools: highly complex but accurately defined siRNA pools eliminate off-target effects. | Q41980019 | ||
CRISPR/Cas9 mutagenesis invalidates a putative cancer dependency targeted in on-going clinical trials | Q42108657 | ||
Improving validation practices in "omics" research | Q42112095 | ||
Complementary information derived from CRISPR Cas9 mediated gene deletion and suppression | Q42224452 | ||
Just like the rest of evolution in Mother Nature, the evolution of cancers may be driven by natural selection, and not by haphazard mutations | Q42236265 | ||
Reproducibility of biomedical research - The importance of editorial vigilance | Q42316762 | ||
Enhanced guide-RNA Design and Targeting Analysis for Precise CRISPR Genome Editing of Single and Consortia of Industrially Relevant and Non-Model Organisms | Q42694500 | ||
Evaluation and control of miRNA-like off-target repression for RNA interference | Q42777701 | ||
An incentive-based approach for improving data reproducibility | Q43732618 | ||
1,500 scientists lift the lid on reproducibility | Q44039870 | ||
Enhanced proofreading governs CRISPR-Cas9 targeting accuracy | Q46347859 | ||
China's publication bazaar | Q46655354 | ||
Targeting Specificity of the CRISPR/Cas9 System | Q47675031 | ||
Improving CRISPR-Cas9 On-Target Specificity. | Q47706611 | ||
Safety, Security, and Policy Considerations for Plant Genome Editing. | Q47919114 | ||
Computational Prediction of CRISPR/Cas9 Target Sites Reveals Potential Off-Target Risks in Human and Mouse | Q47992606 | ||
How should medical science change? | Q48098966 | ||
Regression of estrone-induced mammary tumors in the rat | Q49120808 | ||
Cancer reproducibility project releases first results. | Q53566286 | ||
Mammary cancer induced by a single feeding of polymucular hydrocarbons, and its suppression. | Q53614294 | ||
Avoidable waste in the production and reporting of research evidence | Q56028127 | ||
Occurrence of cancer in rats treated with oestrone | Q57226033 | ||
Where next with peer-review? | Q58994619 | ||
Reality check on reproducibility | Q59068878 | ||
Enzyme activities in regressing estrone-induced mammary tumors of the rat | Q69551590 | ||
Ribo-gnome: the big world of small RNAs | Q29615681 | ||
Policy: NIH plans to enhance reproducibility | Q29616124 | ||
Protein multiplicity can lead to misconduct in western blotting and misinterpretation of immunohistochemical staining results, creating much conflicting data | Q30240288 | ||
Limitations are not properly acknowledged in the scientific literature | Q30483405 | ||
The Inherent Drawbacks of the Pressure to Publish in Health Sciences: Good or Bad Science | Q30488578 | ||
Reproducibility2020: Progress and priorities | Q30492016 | ||
Online GESS: prediction of miRNA-like off-target effects in large-scale RNAi screen data by seed region analysis | Q30831501 | ||
c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations | Q31929763 | ||
Combined Inactivation of MYC and K-Ras oncogenes reverses tumorigenesis in lung adenocarcinomas and lymphomas | Q33332189 | ||
It Is Imperative to Establish a Pellucid Definition of Chimeric RNA and to Clear Up a Lot of Confusion in the Relevant Research | Q33624325 | ||
Production of recombinant antibodies using bacteriophages | Q33643027 | ||
Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens | Q33654299 | ||
Reversible tumorigenesis by MYC in hematopoietic lineages | Q33874286 | ||
New methods as alternative or corrective measures for the pitfalls and artifacts of reverse transcription and polymerase chain reactions (RT-PCR) in cloning chimeric or antisense-accompanied RNA | Q33953031 | ||
Computational detection and suppression of sequence-specific off-target phenotypes from whole genome RNAi screens | Q33983441 | ||
Reproducibility in science: improving the standard for basic and preclinical research | Q34042907 | ||
c-Myc in breast cancer | Q34055118 | ||
MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer | Q34357796 | ||
Gist of Dr. Katsusaburo Yamagiwa's papers entitled "Experimental study on the pathogenesis of epithelial tumors" (I to VI reports). | Q34390239 | ||
Pseudogenes as weaknesses of ACTB (Actb) and GAPDH (Gapdh) used as reference genes in reverse transcription and polymerase chain reactions | Q34395392 | ||
Function of alternative splicing | Q34554255 | ||
Roles of androgens in the development, growth, and carcinogenesis of the mammary gland | Q34565492 | ||
On the reproducibility of science: unique identification of research resources in the biomedical literature | Q34986389 | ||
Myc-induced liver tumors in transgenic zebrafish can regress in tp53 null mutation | Q35001641 | ||
Characterization of pancreatic lesions from MT-tgf alpha, Ela-myc and MT-tgf alpha/Ela-myc single and double transgenic mice | Q35016285 | ||
Possible formation of mitochondrial-RNA containing chimeric or trimeric RNA implies a post-transcriptional and post-splicing mechanism for RNA fusion | Q35034950 | ||
Histopathogenesis of 7,12-diemthylbenz(a)anthracene-induced rat mammary tumors | Q35053066 | ||
Phage antibody display libraries: a powerful antibody discovery platform for immunotherapy. | Q35419158 | ||
Mammary tumors of the rat: a review | Q35533930 | ||
An inducible kras(V12) transgenic zebrafish model for liver tumorigenesis and chemical drug screening. | Q35665032 | ||
gespeR: a statistical model for deconvoluting off-target-confounded RNA interference screens | Q35800841 | ||
Skin tumors following a single application of methylcholanthrene in C57 brown mice. | Q35972034 | ||
Studies in carcinogenesis: XI. Development of skin tumors in mice painted with 3:4-benzpyrene and creosote oil fractions | Q35972245 | ||
Spontaneous regression of induced mammary tumours in rats | Q36127216 | ||
Tumor dormancy and MYC inactivation: pushing cancer to the brink of normalcy | Q36147630 | ||
Rehabilitation of cancer through oncogene inactivation | Q36162935 | ||
Basic anatomy and tumor biology of the RPS6KA6 gene that encodes the p90 ribosomal S6 kinase-4. | Q36188228 | ||
Biomedical Journals and Preprint Services: Friends or Foes? | Q36229851 | ||
Rapid induction of mammary carcinoma in the rat and the influence of hormones on the tumors | Q36264079 | ||
High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding | Q36369721 | ||
Tumor dormancy: death and resurrection of cancer as seen through transgenic mouse models | Q36575307 | ||
Conditional transgenic models define how MYC initiates and maintains tumorigenesis | Q36578360 | ||
Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene | Q36692660 | ||
The Predominant Proteins that React to the MC-20 Estrogen Receptor Alpha Antibody Differ in Molecular Weight between the Mammary Gland and Uterus in the Mouse and Rat. | Q36735733 | ||
Histological complexities of pancreatic lesions from transgenic mouse models are consistent with biological and morphological heterogeneity of human pancreatic cancer | Q36759171 | ||
Structure-Guided Control of siRNA Off-Target Effects | Q37130349 | ||
Tumor dormancy and oncogene addiction | Q37286246 | ||
Expression profile of microRNAs in c-Myc induced mouse mammary tumors | Q37439539 | ||
Cyclin-dependent kinase 4 may be expressed as multiple proteins and have functions that are independent of binding to CCND and RB and occur at the S and G 2/M phases of the cell cycle | Q37530267 | ||
Males develop faster and more severe hepatocellular carcinoma than females in krasV12 transgenic zebrafish | Q37602180 | ||
From rabbit antibody repertoires to rabbit monoclonal antibodies | Q37739483 | ||
Reviewing once more the c-myc and Ras collaboration: converging at the cyclin D1-CDK4 complex and challenging basic concepts of cancer biology | Q37825724 | ||
Reducing waste from incomplete or unusable reports of biomedical research | Q38177450 | ||
Critical appraisal of quantitative PCR results in colorectal cancer research: can we rely on published qPCR results? | Q38178402 | ||
Concise review: dedifferentiation meets cancer development: proof of concept for epigenetic cancer | Q38239816 | ||
Enhancing reproducibility: Failures from Reproducibility Initiatives underline core challenges | Q38378266 | ||
Induced pluripotency and oncogenic transformation are related processes | Q38494976 | ||
Talking the talk, but not walking the walk: RT-qPCR as a paradigm for the lack of reproducibility in molecular research | Q38630683 | ||
The earth is flat (p > 0.05): significance thresholds and the crisis of unreplicable research | Q38683193 | ||
Irreproducibility in Preclinical Biomedical Research: Perceptions, Uncertainties, and Knowledge Gaps | Q38699688 | ||
A patient called Medical Research | Q38742332 | ||
Reproducibility: Respect your cells! | Q38746267 | ||
Genome-wide target specificities of CRISPR RNA-guided programmable deaminases | Q38842681 | ||
The challenges with the validation of research antibodies. | Q38868120 | ||
Explicit Modeling of siRNA-Dependent On- and Off-Target Repression Improves the Interpretation of Screening Results | Q38953295 | ||
Isoforms of wild type proteins often appear as low molecular weight bands on SDS-PAGE. | Q38987507 | ||
Sensitivity, specificity, and reproducibility of RNA-Seq differential expression calls. | Q39043455 | ||
The credibility crisis in research: Can economics tools help? | Q39264517 | ||
P275 | copyright license | Creative Commons Attribution-NonCommercial | Q6936496 |
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | medical research | Q2752427 |
P304 | page(s) | 309-322 | |
P577 | publication date | 2018-01-19 | |
P1433 | published in | International Journal of Medical Sciences | Q10927439 |
P1476 | title | While it is not deliberate, much of today's biomedical research contains logical and technical flaws, showing a need for corrective action | |
P478 | volume | 15 |
Q90746119 | Evidence for immortality and autonomy in animal cancer models is often not provided, which causes confusion on key issues of cancer biology |
Q89965056 | High Fidelity of Mouse Models Mimicking Human Genetic Skeletal Disorders |
Q60312790 | Spontaneous Cancers, But Not Many Induced Ones in Animals, Resemble Semi-New Organisms that Possess a Unique Programmed Cell Death Mode Different from Apoptosis, Senescent Death, Necrosis and Stress-Induced Cell Death |
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