| scholarly article | Q13442814 |
| P2093 | author name string | Yang Lu | |
| Akihiko Yoshimura | |||
| Kazuko Saeki | |||
| Giichi Takaesu | |||
| Takashi Kobayashi | |||
| Ryoko Yoshida | |||
| Satoru Fukuyama | |||
| Hiroshi Shiraishi | |||
| P2860 | cites work | Cloning and characterization of novel CIS family genes | Q24321480 |
| Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3 | Q24555816 | ||
| Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain | Q28140535 | ||
| A novel oncostatin M-inducible gene OIG37 forms a gene family with MyD118 and GADD45 and negatively regulates cell growth | Q28142637 | ||
| SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130 | Q28142716 | ||
| The STATs of cancer--new molecular targets come of age | Q29614601 | ||
| Stat3 as an oncogene | Q29614606 | ||
| Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors | Q33941380 | ||
| Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3. | Q34329517 | ||
| Suppression of epithelial apoptosis and delayed mammary gland involution in mice with a conditional knockout of Stat3. | Q35207498 | ||
| Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130 | Q35777741 | ||
| Genome-wide analysis of STAT target genes: elucidating the mechanism of STAT-mediated oncogenesis | Q35946736 | ||
| The role of IL-6 and STAT3 in inflammation and cancer | Q36274467 | ||
| Signal transduction of inflammatory cytokines and tumor development | Q36492439 | ||
| The genes induced by signal transducer and activators of transcription (STAT)3 and STAT5 in mammary epithelial cells define the roles of these STATs in mammary development. | Q38318687 | ||
| Transcriptional activation of the p21(WAF1,CIP1,SDI1) gene by interleukin-6 type cytokines. A prerequisite for their pro-differentiating and anti-apoptotic effects on human osteoblastic cells | Q38334647 | ||
| SOCS3 regulates the plasticity of gp130 signaling | Q38354507 | ||
| SOCS3 negatively regulates IL-6 signaling in vivo | Q38354512 | ||
| SOCS3: an essential regulator of LIF receptor signaling in trophoblast giant cell differentiation | Q39698984 | ||
| Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways | Q40399370 | ||
| Stat3-induced apoptosis requires a molecular switch in PI(3)K subunit composition | Q40442177 | ||
| Tyrosine phosphorylation disrupts elongin interaction and accelerates SOCS3 degradation | Q40642728 | ||
| The N-terminal truncated isoform of SOCS3 translated from an alternative initiation AUG codon under stress conditions is stable due to the lack of a major ubiquitination site, Lys-6. | Q40686285 | ||
| Suppressors of cytokine signaling (SOCS)-1 and SOCS-3 are induced by CpG-DNA and modulate cytokine responses in APCs | Q40801352 | ||
| Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: role of activated STAT3 signaling | Q40837817 | ||
| STAT3 orchestrates contradictory signals in cytokine-induced G1 to S cell-cycle transition | Q40993836 | ||
| Involvement of STAT3 in the granulocyte colony-stimulating factor-induced differentiation of myeloid cells | Q41089142 | ||
| Loss of SOCS3 in T helper cells resulted in reduced immune responses and hyperproduction of interleukin 10 and transforming growth factor-beta 1 | Q42766950 | ||
| Independent and cooperative activation of chromosomal c-fos promoter by STAT3. | Q44324683 | ||
| Activation of STAT3 by IL-6 and IL-10 in primary human macrophages is differentially modulated by suppressor of cytokine signaling 3. | Q44355411 | ||
| A dual, non-redundant, role for LIF as a regulator of development and STAT3-mediated cell death in mammary gland | Q44480678 | ||
| IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages | Q46376203 | ||
| SOCS3 is a physiological negative regulator for granulopoiesis and granulocyte colony-stimulating factor receptor signaling. | Q47292718 | ||
| Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity | Q47314567 | ||
| SOCS3 is a critical physiological negative regulator of G-CSF signaling and emergency granulopoiesis. | Q51027830 | ||
| Deletion of the SOCS3 gene in liver parenchymal cells promotes hepatitis-induced hepatocarcinogenesis. | Q53344106 | ||
| Loss of SOCS3 in the liver promotes fibrosis by enhancing STAT3-mediated TGF-beta1 production. | Q54618183 | ||
| Differential Activation of Acute Phase Response Factor/STAT3 and STAT1 via the Cytoplasmic Domain of the Interleukin 6 Signal Transducer gp130 | Q56690299 | ||
| P433 | issue | 48 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | apoptotic process | Q14599311 |
| P1104 | number of pages | 8 | |
| P304 | page(s) | 36683-36690 | |
| P577 | publication date | 2006-10-06 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Loss of SOCS3 gene expression converts STAT3 function from anti-apoptotic to pro-apoptotic. | |
| P478 | volume | 281 |
| Q38828603 | Additive effects of eukaryotic co‑expression plasmid carrying GRIM‑19 and LKB1 genes on breast cancer in vitro and in vivo |
| Q41958588 | Alveolar epithelial cells in idiopathic pulmonary fibrosis display upregulation of TRAIL, DR4 and DR5 expression with simultaneous preferential over-expression of pro-apoptotic marker p53. |
| Q36002733 | Apoptosis and inflammation: role of adipokines in inflammatory bowel disease |
| Q92648538 | Cigarette smoke exposure reduces leukemia inhibitory factor levels during respiratory syncytial viral infection |
| Q39220977 | Essential role of JAK/STAT pathway in the induction of cell cycle arrest in macrophages infected with periodontopathic bacterium Aggregatibacter actinomycetemcomitans |
| Q35973308 | Expression of interleukin-8 receptor CXCR2 and suppressor of cytokine signaling-3 in astrocytic tumors |
| Q35122777 | Gene silencing of SOCS3 by siRNA intranasal delivery inhibits asthma phenotype in mice |
| Q33425926 | High-fat diet induces apoptosis of hypothalamic neurons |
| Q39082160 | Human metapneumovirus inhibits the IL-6-induced JAK/STAT3 signalling cascade in airway epithelium. |
| Q42066620 | IL-6 cytoprotection in hyperoxic acute lung injury occurs via suppressor of cytokine signaling-1-induced apoptosis signal-regulating kinase-1 degradation |
| Q35137626 | IL-6 promotes acute and chronic inflammatory disease in the absence of SOCS3. |
| Q33634642 | Immunohistochemical analysis of IL-6, IL-8/CXCR2 axis, Tyr p-STAT-3, and SOCS-3 in lymph nodes from patients with chronic lymphocytic leukemia: correlation between microvascular characteristics and prognostic significance. |
| Q36177778 | Knockdown of stat3 expression by RNAi inhibits in vitro growth of human ovarian cancer |
| Q30430038 | Leptin signaling in intestinal epithelium mediates resistance to enteric infection by Entamoeba histolytica |
| Q34306309 | Leukemia inhibitory factor protects the lung during respiratory syncytial viral infection |
| Q41502830 | Leukocyte antigen-related protein tyrosine phosphatase negatively regulates hydrogen peroxide-induced vascular smooth muscle cell apoptosis |
| Q34275385 | Organogenesis and tumorigenesis: Insight from the JAK/STAT pathway in the Drosophila eye |
| Q42116196 | Potentiation of astrogliogenesis by STAT3-mediated activation of bone morphogenetic protein-Smad signaling in neural stem cells |
| Q39704573 | Protective properties of inhaled IL-22 in a model of ventilator-induced lung injury. |
| Q59350543 | Pulmonary phagocyte-derived NPY controls the pathology of severe influenza virus infection |
| Q52930721 | Role of SOCS3 in the Jak/stat3 pathway in the human placenta: different mechanisms for preterm and term labor. |
| Q38239660 | SOCS Proteins in Macrophage Polarization and Function. |
| Q35927538 | SOCS, Inflammation, and Autoimmunity |
| Q43135527 | SOCS3 regulates p21 expression and cell cycle arrest in response to DNA damage. |
| Q38823319 | SOCS3 revisited: a broad regulator of disease, now ready for therapeutic use? |
| Q28649788 | SOCS3 silencing attenuates eosinophil functions in asthma patients |
| Q61805100 | Suppressor of Cytokine Signaling 3 (SOCS3) Degrades p65 and Regulate HIV-1 Replication |
| Q37374334 | Suppressors of cytokine-signaling proteins induce insulin resistance in the retina and promote survival of retinal cells |
| Q38938226 | Synergistic effects of eukaryotic co-expression plasmid-based STAT3-specific siRNA and LKB1 on ovarian cancer in vitro and in vivo |
| Q34035704 | The PI3K regulatory subunits p55α and p50α regulate cell death in vivo. |
| Q35248175 | The construction of common and specific significance subnetworks of Alzheimer's disease from multiple brain regions |
| Q41052928 | The microRNA miR-155 controls CD8(+) T cell responses by regulating interferon signaling. |
| Q33589279 | The role of CXC-chemokine receptor CXCR2 and suppressor of cytokine signaling-3 (SOCS-3) in renal cell carcinoma |
| Q33772382 | Transforming growth factor-{beta} coordinately induces suppressor of cytokine signaling 3 and leukemia inhibitory factor to suppress osteoclast apoptosis. |
| Q38877630 | Upregulation of GRIM-19 inhibits the growth and invasion of human breast cancer cells |
| Q91900221 | miR-221 Augments TRAIL-Mediated Apoptosis in Prostate Cancer Cells by Inducing Endogenous TRAIL Expression and Targeting the Functional Repressors SOCS3 and PIK3R1 |
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