| scholarly article | Q13442814 |
| P356 | DOI | 10.1038/SJ.ONC.1203227 |
| P698 | PubMed publication ID | 10644993 |
| P50 | author | Ragnhild A. Lothe | Q11996941 |
| Manel Esteller | Q3816008 | ||
| Lauri Aaltonen | Q23039716 | ||
| Stephen B. Baylin | Q28113000 | ||
| James G. Herman | Q59569278 | ||
| P2093 | author name string | Paul G Corn | |
| Egle Avizienyte | |||
| P2860 | cites work | Loss of LKB1 kinase activity in Peutz-Jeghers syndrome, and evidence for allelic and locus heterogeneity | Q24539769 |
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| Peutz-Jeghers syndrome | Q33679883 | ||
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| Did the four human cancer cell lines DLD-1, HCT-15, HCT-8, and HRT-18 originate from one and the same patient? | Q42819326 | ||
| Genetic pathways of colorectal carcinogenesis rarely involve the PTEN and LKB1 genes outside the inherited hamartoma syndromes | Q42850964 | ||
| Cultural and Antigenic Properties of Newly Established Cell Strains Derived From Adenocarcinomas of the Human Colon and Rectum | Q47872753 | ||
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| A family with Peutz-Jeghers syndrome and bilateral breast cancer | Q57650862 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Peutz-Jeghers syndrome | Q1544989 |
| P304 | page(s) | 164-168 | |
| P577 | publication date | 2000-01-06 | |
| P1433 | published in | Oncogene | Q1568657 |
| P1476 | title | Epigenetic inactivation of LKB1 in primary tumors associated with the Peutz-Jeghers syndrome | |
| P478 | volume | 19 |
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| Q36283354 | Altered LKB1/AMPK/TSC1/TSC2/mTOR signaling causes disruption of Sertoli cell polarity and spermatogenesis |
| Q39517661 | Altered LKB1/CREB-regulated transcription co-activator (CRTC) signaling axis promotes esophageal cancer cell migration and invasion. |
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| Q37204613 | Breaking the epithelial polarity barrier in cancer: the strange case of LKB1/PAR-4 |
| Q35749872 | Brush border myosin Ia has tumor suppressor activity in the intestine. |
| Q35761237 | Colorectal cancer: a model for epigenetic tumorigenesis |
| Q61799012 | Constitutive Promoter Hypermethylation Can Be a Predisposing Event in Isolated Early-Onset Breast Cancer |
| Q28472991 | Convergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosis |
| Q33337445 | CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future |
| Q33870798 | DNA hypermethylation in tumorigenesis: epigenetics joins genetics |
| Q34290318 | DNA methylation, chromatin inheritance, and cancer |
| Q30993657 | DNA methylation, methyltransferases, and cancer |
| Q34547049 | Distinctive gene expression of human lung adenocarcinomas carrying LKB1 mutations. |
| Q35118477 | Epigenetics: The Role of Methylation in the Mechanism of Action of Tumor Suppressor Genes |
| Q36459906 | Expression and transcriptional profiling of the LKB1 tumor suppressor in cervical cancer cells |
| Q52749536 | Expression of STK11 gene and its promoter activity in MCF control and cancer cells. |
| Q39001461 | Frequent hypermethylation of WNT pathway genes in laryngeal squamous cell carcinomas |
| Q34193241 | Gene expression of the tumour suppressor LKB1 is mediated by Sp1, NF-Y and FOXO transcription factors |
| Q36811822 | Gene-set Analysis with CGI Information for Differential DNA Methylation Profiling |
| Q54651537 | Genetic Alterations of the LKB1 Gene in Head and Neck Cancer |
| Q34544116 | Genetic analysis of the LKB1/STK11 gene in hepatocellular carcinomas |
| Q36697151 | Genetic and epigenetic analyses of MBD3 in colon and lung cancer. |
| Q34094993 | Genetic variation in a metabolic signaling pathway and colon and rectal cancer risk: mTOR, PTEN, STK11, RPKAA1, PRKAG2, TSC1, TSC2, PI3K and Akt1. |
| Q37727837 | Germinal center kinases in immune regulation. |
| Q35868041 | Highly penetrant hereditary cancer syndromes. |
| Q33721668 | Homozygous deletion of the STK11/LKB1 locus and the generation of novel fusion transcripts in cervical cancer cells |
| Q26801711 | Induced pluripotent stem cell technology for dissecting the cancer epigenome |
| Q34156001 | Induction of cyclooxygenase-2 in a mouse model of Peutz-Jeghers polyposis |
| Q36277422 | Inherited polyposis syndromes: molecular mechanisms, clinicopathology, and genetic testing |
| Q33835913 | Interplay between epigenetics and metabolism in oncogenesis: mechanisms and therapeutic approaches |
| Q38994951 | LKB1 Loss induces characteristic patterns of gene expression in human tumors associated with NRF2 activation and attenuation of PI3K-AKT. |
| Q38354509 | LKB1 Tumor Suppressor: Therapeutic Opportunities Knock when LKB1 Is Inactivated. |
| Q39026772 | LKB1 as a Tumor Suppressor in Uterine Cancer: Mouse Models and Translational Studies |
| Q28205561 | LKB1 associates with Brg1 and is necessary for Brg1-induced growth arrest |
| Q37207745 | LKB1 catalytic activity contributes to estrogen receptor alpha signaling |
| Q45827485 | LKB1 downregulation may be independent of promoter methylation or FOXO3 expression in head and neck cancer. |
| Q37165210 | LKB1 haploinsufficiency cooperates with Kras to promote pancreatic cancer through suppression of p21-dependent growth arrest |
| Q34825535 | LKB1 inhibits breast cancer partially through repressing the Hedgehog signaling pathway |
| Q54348800 | LKB1 loss at transcriptional level promotes tumor malignancy and poor patient outcomes in colorectal cancer. |
| Q37829489 | LKB1 loss of function studied in vivo |
| Q38910483 | LKB1 suppresses proliferation and invasion of prostate cancer through hedgehog signaling pathway |
| Q37333592 | LKB1; linking cell structure and tumor suppression |
| Q39601869 | Liver kinase B1 (LKB1) in the pathogenesis of UVB-induced murine basal cell carcinoma |
| Q34899298 | Liver kinase B1 (LKB1) in the pathogenesis of epithelial cancers |
| Q34458796 | Loss of LKB1 in high-grade endometrial carcinoma: LKB1 is a novel transcriptional target of p53. |
| Q73670302 | Loss of Stk11/Lkb1 expression in pancreatic and biliary neoplasms |
| Q34527075 | Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation |
| Q92316777 | Metabolic Dysregulations and Epigenetics: A Bidirectional Interplay that Drives Tumor Progression |
| Q64245167 | Metabolic Reprogramming in Breast Cancer and Its Therapeutic Implications |
| Q52668163 | Metformin and berberine, two versatile drugs in treatment of common metabolic diseases. |
| Q34378429 | Methylation and colorectal cancer |
| Q28364163 | Methylation matters |
| Q41614903 | Methylation of STK11 promoter is a risk factor for tumor stage and survival in clear cell renal cell carcinoma |
| Q36547059 | Minimal deviation adenocarcinoma of the cervix and tumorlets of sex-cord stromal tumor with annular tubules of the ovary in Peutz-Jeghers syndrome |
| Q26769935 | Molecular approach to genetic and epigenetic pathogenesis of early-onset colorectal cancer |
| Q40074388 | Molecular insights into Peutz-Jeghers syndrome: two probands with a germline mutation of LKB1. |
| Q28201622 | Mutation screening at the RNA level of the STK11/LKB1 gene in Peutz-Jeghers syndrome reveals complex splicing abnormalities and a novel mRNA isoform (STK11 c.597(insertion mark)598insIVS4) |
| Q36234845 | Mutations in the human LKB1/STK11 gene |
| Q37679354 | Polarity protein alterations in carcinoma: a focus on emerging roles for polarity regulators |
| Q41144658 | Prognostic significance of LKB1 promoter methylation in cutaneous malignant melanoma |
| Q34087196 | Radiation necrosis following treatment of high grade glioma--a review of the literature and current understanding |
| Q40346993 | Reactive lipid species from cyclooxygenase-2 inactivate tumor suppressor LKB1/STK11: cyclopentenone prostaglandins and 4-hydroxy-2-nonenal covalently modify and inhibit the AMP-kinase kinase that modulates cellular energy homeostasis and protein tra |
| Q34358845 | Recent progress on liver kinase B1 (LKB1): expression, regulation, downstream signaling and cancer suppressive function |
| Q28189311 | Regulation of the Wnt signalling component PAR1A by the Peutz-Jeghers syndrome kinase LKB1 |
| Q36768322 | Restoration of ASC expression sensitizes colorectal cancer cells to genotoxic stress-induced caspase-independent cell death |
| Q40631284 | Restoration of Silenced Peutz-Jeghers Syndrome Gene, LKB1, Induces Apoptosis in Pancreatic Carcinoma Cells |
| Q38708958 | Role of CPS1 in Cell Growth, Metabolism and Prognosis in LKB1-Inactivated Lung Adenocarcinoma |
| Q93035905 | Role of INSL4 Signaling in Sustaining the Growth and Viability of LKB1-Inactivated Lung Cancer |
| Q37252718 | Role of LKB1 in lung cancer development |
| Q34066238 | Role of Lkb1, the causative gene of Peutz-Jegher's syndrome, in embryogenesis and polyposis |
| Q37815730 | SIRT1 and AMPK in regulating mammalian senescence: a critical review and a working model |
| Q24685646 | STK11/LKB1 Peutz-Jeghers gene inactivation in intraductal papillary-mucinous neoplasms of the pancreas |
| Q33425903 | Somatic LKB1 mutations promote cervical cancer progression |
| Q28076017 | Stem cell dynamics and pretumor progression in the intestinal tract |
| Q43235502 | Stochastic dynamics of cancer initiation |
| Q38938226 | Synergistic effects of eukaryotic co-expression plasmid-based STAT3-specific siRNA and LKB1 on ovarian cancer in vitro and in vivo |
| Q38016107 | Targeting metabolism for cancer treatment and prevention: metformin, an old drug with multi-faceted effects |
| Q56421597 | The fundamental role of epigenetic events in cancer |
| Q37389066 | The molecular mechanisms that underlie the tumor suppressor function of LKB1. |
| Q35596876 | The negative regulators of Wnt pathway-DACH1, DKK1, and WIF1 are methylated in oral and oropharyngeal cancer and WIF1 methylation predicts shorter survival |
| Q33783277 | The transcriptional responsiveness of LKB1 to STAT-mediated signaling is differentially modulated by prolactin in human breast cancer cells |
| Q37934215 | The tumor suppressor kinase LKB1: lessons from mouse models |
| Q91861384 | Towards quantitative and multiplexed in vivo functional cancer genomics |
| Q40840350 | Trans-regulated silencing and reactivation of TP53 tumor suppressor gene in malignant transformation and its reversion |
| Q39209841 | Underexpression of tumour suppressor LKB1 in clear cell renal cell carcinoma is common and confers growth advantage in vitro and in vivo |
| Q36951807 | cAMP/CREB-regulated LINC00473 marks LKB1-inactivated lung cancer and mediates tumor growth. |
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