Cinaciguat, a soluble guanylate cyclase activator: results from the randomized, controlled, phase IIb COMPOSE programme in acute heart failure syndromes

article by Mihai Gheorghiade et al published September 2012 in European Journal of Heart Failure

Cinaciguat, a soluble guanylate cyclase activator: results from the randomized, controlled, phase IIb COMPOSE programme in acute heart failure syndromes is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/EURJHF/HFS093
P698PubMed publication ID22713287

P50authorAlexandre MebazaaQ63107378
Phillip D LevyQ89918839
Christina NowackQ114291637
Stephen J GreeneQ125217678
Aldo P. MaggioniQ40310748
Mihai GheorghiadeQ60059386
Gerasimos FilippatosQ63107352
P2093author name stringRoberto Ferrari
Erland Erdmann
P2860cites workNO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potentialQ24656131
Structure of cinaciguat (BAY 58-2667) bound to Nostoc H-NOX domain reveals insights into heme-mimetic activation of the soluble guanylyl cyclaseQ27661554
Clinical trials update: highlights of the scientific sessions of the XXIII Congress of the European Society of Cardiology--WARIS II, ESCAMI, PAFAC, RITZ-1 and TIMEQ28191847
Effect of nesiritide in patients with acute decompensated heart failureQ28242547
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Evaluation study of congestive heart failure and pulmonary artery catheterization effectiveness: the ESCAPE trialQ34456841
Acute heart failure syndromes: current state and framework for future researchQ34478054
Common causes of troponin elevations in the absence of acute myocardial infarction: incidence and clinical significanceQ35770005
Effects of tolvaptan on dyspnoea relief from the EVEREST trialsQ37343857
Clinical trials of pharmacological therapies in acute heart failure syndromes: lessons learned and directions forwardQ37710255
Implantable cardioverter-defibrillator implementation in acute heart failure syndromes: unanswered questionsQ37855663
The impact of early standard therapy on dyspnoea in patients with acute heart failure: the URGENT-dyspnoea studyQ39296001
Hemodynamic and clinical effects of tezosentan, an intravenous dual endothelin receptor antagonist, in patients hospitalized for acute decompensated heart failureQ44505481
Cinaciguat (BAY 58-2667) improves cardiopulmonary hemodynamics in patients with acute decompensated heart failure.Q46006828
Targeting heme-oxidized soluble guanylate cyclase in experimental heart failureQ48260348
Cardioprotective effects in aged spontaneously hypertensive rats due to chronic stimulation/activation of sGC without hypotension.Q55211329
A proposal to standardize dyspnoea measurement in clinical trials of acute heart failure syndromes: the need for a uniform approachQ57630719
P433issue9
P921main subjectheart failureQ181754
acute decompensated heart failureQ4677930
P304page(s)1056-1066
P577publication date2012-09-01
P1433published inEuropean Journal of Heart FailureQ5017954
P1476titleCinaciguat, a soluble guanylate cyclase activator: results from the randomized, controlled, phase IIb COMPOSE programme in acute heart failure syndromes
P478volume14

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