| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.2217/EPI-2017-0027 |
| P698 | PubMed publication ID | 28617138 |
| P50 | author | Marcel Kwiatkowski | Q83575206 |
| Rainer Bischoff | Q38590109 | ||
| P2093 | author name string | Frank J Dekker | |
| Thea van den Bosch | |||
| P2860 | cites work | NF-kappaB and activator protein 1 response elements and the role of histone modifications in IL-1beta-induced TGF-beta1 gene transcription | Q42488247 |
| Histone deacetylase inhibitors MS-275 and SAHA induced growth arrest and suppressed lipopolysaccharide-stimulated NF-kappaB p65 nuclear accumulation in human rheumatoid arthritis synovial fibroblastic E11 cells | Q43084969 | ||
| Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS. | Q43143715 | ||
| Thiol-Based Potent and Selective HDAC6 Inhibitors Promote Tubulin Acetylation and T-Regulatory Cell Suppressive Function | Q43175411 | ||
| Expression and activity of histone deacetylases in human asthmatic airways | Q44086893 | ||
| Histone acetylase and deacetylase activity in alveolar macrophages and blood mononocytes in asthma | Q44846614 | ||
| Trichostatin A attenuates airway inflammation in mouse asthma model | Q45222913 | ||
| Induction of Foxp3+ regulatory T cells with histone deacetylase inhibitors | Q46055067 | ||
| Activity and expression of histone acetylases and deacetylases in inflammatory phenotypes of asthma | Q48136302 | ||
| Defective sirtuin-1 increases IL-4 expression through acetylation of GATA-3 in patients with severe asthma. | Q51568936 | ||
| Chemoproteomics reveals time-dependent binding of histone deacetylase inhibitors to endogenous repressor complexes. | Q51731542 | ||
| Activation of NF-kappaB transcription factor in asthma death. | Q51753354 | ||
| Frequency of Foxp3+CD4CD25+ T cells is associated with the phenotypes of allergic asthma. | Q51840768 | ||
| Glucocorticoid receptor β and histone deacetylase 1 and 2 expression in the airways of severe asthma. | Q54334722 | ||
| Decreased histone deacetylase activity in chronic obstructive pulmonary disease. | Q54664094 | ||
| Effects of the Histone Deacetylase Inhibitor, Trichostatin A, in a Chronic Allergic Airways Disease Model in Mice | Q58049795 | ||
| Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease | Q22299313 | ||
| Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase | Q24293656 | ||
| The functional interactome landscape of the human histone deacetylase family | Q24294822 | ||
| Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes | Q24338109 | ||
| Histone deacetylases (HDACs): characterization of the classical HDAC family | Q24535587 | ||
| ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESIS | Q24629431 | ||
| COPD immunopathology | Q26749575 | ||
| Real-time imaging of histone H4K12-specific acetylation determines the modes of action of histone deacetylase and bromodomain inhibitors | Q27667522 | ||
| Histone Deacetylase (HDAC) Inhibitor Kinetic Rate Constants Correlate with Cellular Histone Acetylation but Not Transcription and Cell Viability | Q27679266 | ||
| Lysine acetylation targets protein complexes and co-regulates major cellular functions | Q27860589 | ||
| The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells | Q27860620 | ||
| The language of covalent histone modifications | Q27860931 | ||
| Histone deacetylase 3 (HDAC 3) as emerging drug target in NF-κB-mediated inflammation | Q28076052 | ||
| Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB. | Q28118359 | ||
| Post-activation turn-off of NF-kappa B-dependent transcription is regulated by acetylation of p65 | Q28213946 | ||
| Duration of nuclear NF-kappaB action regulated by reversible acetylation | Q28215080 | ||
| Histone acetylation and deacetylation: importance in inflammatory lung diseases | Q28237379 | ||
| Regulatory T cells exert checks and balances on self tolerance and autoimmunity | Q28267935 | ||
| The regulation of IL-10 production by immune cells | Q29615479 | ||
| Anticancer activities of histone deacetylase inhibitors | Q29616624 | ||
| The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men | Q29619117 | ||
| Acetylation site specificities of lysine deacetylase inhibitors in human cells | Q30002375 | ||
| Divergent roles of histone deacetylase 6 (HDAC6) and histone deacetylase 11 (HDAC11) on the transcriptional regulation of IL10 in antigen presenting cells | Q33607294 | ||
| Histone deacetylase inhibitors activate NF-kappaB in human leukemia cells through an ATM/NEMO-related pathway | Q33744417 | ||
| Dynamic interactions between TIP60 and p300 regulate FOXP3 function through a structural switch defined by a single lysine on TIP60. | Q33782307 | ||
| The clinical development of histone deacetylase inhibitors as targeted anticancer drugs | Q33829390 | ||
| Blockade of histone deacetylase inhibitor-induced RelA/p65 acetylation and NF-kappaB activation potentiates apoptosis in leukemia cells through a process mediated by oxidative damage, XIAP downregulation, and c-Jun N-terminal kinase 1 activation | Q33863049 | ||
| Impaired macrophage phagocytosis of bacteria in severe asthma. | Q33864335 | ||
| Inhaled corticosteroids in chronic obstructive pulmonary disease: a pro-con perspective | Q34065276 | ||
| TH17 cells in asthma and COPD. | Q34098172 | ||
| Class I histone deacetylase inhibitor entinostat suppresses regulatory T cells and enhances immunotherapies in renal and prostate cancer models | Q34150018 | ||
| Absence of Foxp3+ regulatory T cells during allergen provocation does not exacerbate murine allergic airway inflammation | Q34447903 | ||
| Enhancement of inflammatory protein expression and nuclear factor Κb (NF-Κb) activity by trichostatin A (TSA) in OP9 preadipocytes | Q34651949 | ||
| Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors | Q34687445 | ||
| Glucocorticosteroids: current and future directions | Q34903070 | ||
| Histone deacetylase inhibitors for treating a spectrum of diseases not related to cancer | Q35016934 | ||
| Histone deacetylase 6 and heat shock protein 90 control the functions of Foxp3(+) T-regulatory cells | Q35096555 | ||
| IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx? | Q35129625 | ||
| FOXP3+ regulatory T cell development and function require histone/protein deacetylase 3. | Q35183865 | ||
| Histone deacetylase inhibitors in clinical studies as templates for new anticancer agents | Q35214924 | ||
| Histone/protein deacetylases control Foxp3 expression and the heat shock response of T-regulatory cells. | Q35300659 | ||
| Estradiol inhibits Th17 cell differentiation through inhibition of RORγT transcription by recruiting the ERα/REA complex to estrogen response elements of the RORγT promoter | Q35329102 | ||
| Histone Deacetylase Inhibitors (HDACi) Cause the Selective Depletion of Bromodomain Containing Proteins (BCPs). | Q35583360 | ||
| Tissue factor pathway inhibitor attenuates the progression of malignant pleural mesothelioma in nude mice | Q35813885 | ||
| Histone/protein deacetylases and T-cell immune responses | Q35849307 | ||
| Decreased Histone Deacetylase 2 (HDAC2) in Peripheral Blood Monocytes (PBMCs) of COPD Patients | Q35904081 | ||
| Elevated H3K18 acetylation in airway epithelial cells of asthmatic subjects | Q35937982 | ||
| Cells adapt to the epigenomic disruption caused by histone deacetylase inhibitors through a coordinated, chromatin-mediated transcriptional response | Q36067075 | ||
| Histone deacetylase inhibitor-mediated cell death is distinct from its global effect on chromatin | Q36283075 | ||
| Effector T cell differentiation: are master regulators of effector T cells still the masters? | Q38576266 | ||
| Histone Deacetylase Inhibitors Promote Mitochondrial Reactive Oxygen Species Production and Bacterial Clearance by Human Macrophages. | Q38741197 | ||
| Inflammatory mechanisms in patients with chronic obstructive pulmonary disease. | Q38845823 | ||
| Inside HDACs with more selective HDAC inhibitors | Q38869201 | ||
| Association between histone hyperacetylation status in memory T lymphocytes and allergen-induced eosinophilic airway inflammation. | Q38893203 | ||
| The Search for Potent, Small-Molecule HDACIs in Cancer Treatment: A Decade After Vorinostat. | Q39127916 | ||
| Oral administration of histone deacetylase inhibitor MS-275 ameliorates neuroinflammation and cerebral amyloidosis and improves behavior in a mouse model. | Q39196413 | ||
| HDAC inhibitor MS-275 attenuates the inflammatory reaction in rat experimental autoimmune prostatitis. | Q39549290 | ||
| FoxP3, GATA-3 and T-bet expression in elderly asthma. | Q39812241 | ||
| Histone deacetylase inhibitors suppress the inducibility of nuclear factor-kappaB by tumor necrosis factor-alpha receptor-1 down-regulation | Q40278633 | ||
| Acetylation of GATA-3 affects T-cell survival and homing to secondary lymphoid organs | Q40370630 | ||
| IL-10 disrupts the Brd4-docking sites to inhibit LPS-induced CXCL8 and TNF-α expression in monocytes: Implications for chronic obstructive pulmonary disease | Q40868198 | ||
| Three novel acetylation sites in the Foxp3 transcription factor regulate the suppressive activity of regulatory T cells | Q42196147 | ||
| Regulatory T cells in induced sputum of asthmatic children: association with inflammatory cytokines | Q36293791 | ||
| SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease. | Q36539471 | ||
| Alveolar macrophages as orchestrators of COPD. | Q36602291 | ||
| Histone deacetylases 6 and 9 and sirtuin-1 control Foxp3+ regulatory T cell function through shared and isoform-specific mechanisms. | Q36702713 | ||
| HDAC inhibition suppresses primary immune responses, enhances secondary immune responses, and abrogates autoimmunity during tumor immunotherapy | Q36740297 | ||
| Reciprocal regulation of RORγt acetylation and function by p300 and HDAC1. | Q36756039 | ||
| HDAC 3-selective inhibitor RGFP966 demonstrates anti-inflammatory properties in RAW 264.7 macrophages and mouse precision-cut lung slices by attenuating NF-κB p65 transcriptional activity. | Q36834101 | ||
| Sirtuins: the 'magnificent seven', function, metabolism and longevity | Q36911415 | ||
| The cytokine network in asthma and chronic obstructive pulmonary disease | Q36955575 | ||
| Immunology of asthma and chronic obstructive pulmonary disease | Q37084506 | ||
| The histone deacetylase inhibitor trichostatin A suppresses murine innate allergic inflammation by blocking group 2 innate lymphoid cell (ILC2) activation | Q37085681 | ||
| Relative corticosteroid insensitivity of peripheral blood mononuclear cells in severe asthma | Q37144279 | ||
| Targeting the NF-kappaB pathway in asthma and chronic obstructive pulmonary disease. | Q37308018 | ||
| Therapeutic effects of histone deacetylase inhibitors in a murine asthma model | Q37358582 | ||
| Histone acetyl transferases as emerging drug targets. | Q37540911 | ||
| Passive smoking impairs histone deacetylase-2 in children with severe asthma. | Q37553296 | ||
| The histone deacetylase HDAC11 regulates the expression of interleukin 10 and immune tolerance | Q37586967 | ||
| Histone deacetylase inhibitors modulate interleukin 6-dependent CD4+ T cell polarization in vitro and in vivo | Q37608561 | ||
| New patented histone deacetylase inhibitors | Q37638742 | ||
| Inhaled corticosteroids in chronic obstructive pulmonary disease: a review. | Q37681569 | ||
| HDAC1-3 inhibitor MS-275 enhances IL10 expression in RAW264.7 macrophages and reduces cigarette smoke-induced airway inflammation in mice | Q37721580 | ||
| Regulatory signal transduction pathways for class IIa histone deacetylases | Q37744144 | ||
| The many paths to asthma: phenotype shaped by innate and adaptive immunity | Q37766451 | ||
| T(H)17 cells in asthma and inflammation | Q37840493 | ||
| Function of histone deacetylase inhibitors in inflammation. | Q37899219 | ||
| HDAC inhibitors in HIV. | Q37956178 | ||
| Glucocorticoid-resistant asthma and novel anti-inflammatory drugs. | Q38015637 | ||
| Transcription and beyond: the role of mammalian class I lysine deacetylases | Q38156341 | ||
| Small molecule inhibitors of histone acetyltransferases and deacetylases are potential drugs for inflammatory diseases. | Q38165621 | ||
| Histone deacetylases and their inhibitors: new implications for asthma and chronic respiratory conditions | Q38169885 | ||
| Targeting histone-modifications in Alzheimer's disease. What is the evidence that this is a promising therapeutic avenue? | Q38184220 | ||
| The growing landscape of lysine acetylation links metabolism and cell signalling | Q38232935 | ||
| Histone deacetylase inhibitors in hematological malignancies and solid tumors | Q38344675 | ||
| Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production | Q38505117 | ||
| P433 | issue | 7 | |
| P304 | page(s) | 1013-1028 | |
| P577 | publication date | 2017-06-15 | |
| P1433 | published in | Epigenomics | Q20737165 |
| P1476 | title | Targeting transcription factor lysine acetylation in inflammatory airway diseases | |
| P478 | volume | 9 |
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