| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Hidde J. Haisma | Q37830344 |
| Frank J Dekker | Q39476878 | ||
| P2093 | author name string | Hidde J Haisma | |
| Frank J Dekker | |||
| P433 | issue | 19-20 | |
| P304 | page(s) | 942-948 | |
| P577 | publication date | 2009-07-02 | |
| P1433 | published in | Drug Discovery Today | Q3040085 |
| P1476 | title | Histone acetyl transferases as emerging drug targets | |
| P478 | volume | 14 |
| Q36102450 | 6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site |
| Q47836122 | A 6-alkylsalicylate histone acetyltransferase inhibitor inhibits histone acetylation and pro-inflammatory gene expression in murine precision-cut lung slices |
| Q33733125 | A combination of p300 and Braf expression in the diagnosis and prognosis of melanoma |
| Q26782981 | A dynamic interface between ubiquitylation and cAMP signaling |
| Q37993058 | A role for cytoskeletal protein acetylation in modulating myometrial activity. |
| Q36055920 | A role for epigenetic changes in the development of retinal neurodegenerative conditions |
| Q34428163 | Acetylation-mediated suppression of transcription-independent memory: bidirectional modulation of memory by acetylation |
| Q36442907 | Activation of tachykinin, neurokinin 3 receptors affects chromatin structure and gene expression by means of histone acetylation |
| Q91991310 | African swine fever virus replication events and cell nucleus: New insights and perspectives |
| Q33927405 | Alcohol exposure decreases CREB binding protein expression and histone acetylation in the developing cerebellum |
| Q35863203 | Altering cancer transcriptomes using epigenomic inhibitors |
| Q50420238 | Anacardic Acids from Cashew Nuts Prevent Behavioral Changes and Oxidative Stress Induced by Rotenone in a Rat Model of Parkinson's Disease. |
| Q28395758 | Anacardic acids from cashew nuts ameliorate lung damage induced by exposure to diesel exhaust particles in mice |
| Q51374049 | Analysis of HDACi-Induced Changes in Chromosomal Passenger Complex Localization. |
| Q42573875 | Androgen receptor signalling in prostate cancer: the functional consequences of acetylation |
| Q33745848 | Application of a high-throughput fluorescent acetyltransferase assay to identify inhibitors of homocitrate synthase |
| Q28577251 | Auto-acetylation stabilizes p300 in cardiac myocytes during acute oxidative stress, promoting STAT3 accumulation and cell survival |
| Q42050418 | Azalysine analogues as probes for protein lysine deacetylation and demethylation |
| Q42128109 | BET bromodomain inhibitors block growth of pancreatic cancer cells in three-dimensional collagen |
| Q27021767 | Beyond the genome: epigenetic mechanisms in lung remodeling |
| Q38704516 | Bioanalytical approaches for the detection of protein acetylation-related enzymes |
| Q38185355 | Bromodomains and their pharmacological inhibitors |
| Q36644882 | C646, a Novel p300/CREB-Binding Protein-Specific Inhibitor of Histone Acetyltransferase, Attenuates Influenza A Virus Infection |
| Q35989524 | CAMKII-conditional deletion of histone deacetylase 2 potentiates acute methamphetamine-induced expression of immediate early genes in the mouse nucleus accumbens |
| Q96111272 | Cellular Location of HNF4α is Linked With Terminal Liver Failure in Humans |
| Q37829708 | Chemical approaches for the detection and synthesis of acetylated proteins |
| Q37825449 | Chemical biology of histone acetyltransferase natural compounds modulators |
| Q37983159 | Chronic pain: emerging evidence for the involvement of epigenetics |
| Q89558878 | Control of mesenchymal stem cell biology by histone modifications |
| Q36699551 | Creb1-Mecp2-(m)CpG complex transactivates postnatal murine neuronal glucose transporter isoform 3 expression |
| Q26850027 | Design of small molecule epigenetic modulators |
| Q37769504 | Development of curcumin as an epigenetic agent |
| Q38818485 | Dietary phytochemicals as epigenetic modifiers in cancer: Promise and challenges |
| Q21296850 | Dietary, metabolic, and potentially environmental modulation of the lysine acetylation machinery |
| Q27681322 | Dimeric structure of p300/CBP associated factor |
| Q34831586 | Distinct roles of the Gcn5 histone acetyltransferase revealed during transient stress-induced reprogramming of the genome |
| Q42141606 | Double null cells reveal that CBP and p300 are dispensable for p53 targets p21 and Mdm2 but variably required for target genes of other signaling pathways |
| Q42820289 | Drug screening for ALS using patient-specific induced pluripotent stem cells |
| Q35937982 | Elevated H3K18 acetylation in airway epithelial cells of asthmatic subjects |
| Q39611465 | Epigenetic Plasticity Drives Adipogenic and Osteogenic Differentiation of Marrow-derived Mesenchymal Stem Cells |
| Q37672061 | Epigenetic contributions to hormonally-mediated sexual differentiation of the brain |
| Q37719605 | Epigenetic control of skeletal muscle fibre type |
| Q36465823 | Epigenetic mechanisms in stroke and epilepsy |
| Q29616621 | Epigenetic protein families: a new frontier for drug discovery |
| Q53084522 | Epigenetically centered evolution in an example of myeloid malignancy. |
| Q38679304 | Epigenetics in Personalized Management of Lung Cancer |
| Q33810295 | Epigenetics meets endocrinology |
| Q38770916 | Epigenetics: A primer for clinicians |
| Q38055065 | Epigenomics and interindividual differences in drug response |
| Q27692571 | Fate determination in mesenchymal stem cells: a perspective from histone-modifying enzymes |
| Q34236804 | Focused examination of the intestinal lamina propria yields greater molecular insight into mechanisms underlying SIV induced immune dysfunction |
| Q36188969 | Fungal KATs/KDACs: A New Highway to Better Antifungal Drugs? |
| Q35574284 | Gcn5 Modulates the Cellular Response to Oxidative Stress and Histone Deacetylase Inhibition. |
| Q36834101 | HDAC 3-selective inhibitor RGFP966 demonstrates anti-inflammatory properties in RAW 264.7 macrophages and mouse precision-cut lung slices by attenuating NF-κB p65 transcriptional activity. |
| Q27316244 | HDAC activity is required during Xenopus tail regeneration |
| Q35182839 | Heparanase-mediated loss of nuclear syndecan-1 enhances histone acetyltransferase (HAT) activity to promote expression of genes that drive an aggressive tumor phenotype |
| Q41645565 | Hierarchy in somatic mutations arising during genomic evolution and progression of follicular lymphoma |
| Q35195856 | High throughput screening identifies modulators of histone deacetylase inhibitors |
| Q94544744 | Histone Deacetylases Inhibitors in Neurodegenerative Diseases, Neuroprotection and Neuronal Differentiation |
| Q30316789 | Histone acetyltransferase inhibitors block neuroblastoma cell growth in vivo |
| Q28082536 | Histone acetyltransferases and histone deacetylases in B- and T-cell development, physiology and malignancy |
| Q33866592 | Histone acetyltransferases are crucial regulators in NF-κB mediated inflammation. |
| Q26745642 | Histone acetyltransferases: challenges in targeting bi-substrate enzymes |
| Q38271597 | Histone modifications: Targeting head and neck cancer stem cells |
| Q37871526 | How to control an infectious bead string: nucleosome-based regulation and targeting of herpesvirus chromatin. |
| Q38514126 | Identification of family determining residues in Jumonji-C lysine demethylases: A sequence-based, family wide classification |
| Q38946242 | Identification of structural features of 2-alkylidene-1,3-dicarbonyl derivatives that induce inhibition and/or activation of histone acetyltransferases KAT3B/p300 and KAT2B/PCAF. |
| Q39286723 | Inhibition of PCAF histone acetyltransferase and cytotoxic effect of N-acylanthranilic acids |
| Q39249234 | Inhibition of PCAF histone acetyltransferase, cytotoxicity and cell permeability of 2-acylamino-1-(3- or 4-carboxy-phenyl)benzamides. |
| Q38363468 | Inhibition of different histone acetyltransferases (HATs) uncovers transcription-dependent and -independent acetylation-mediated mechanisms in memory formation |
| Q91678511 | Inhibition of histone deacetylase 1 (HDAC1) and HDAC2 enhances CRISPR/Cas9 genome editing |
| Q38547122 | Inhibitors of emerging epigenetic targets for cancer therapy: a patent review (2010-2014). |
| Q47869988 | Insights into intermolecular interactions, electrostatic properties and the stability of C646 in the binding pocket of p300 histone acetyltransferase enzyme: a combined molecular dynamics and charge density study |
| Q35003657 | Interpreting clinical assays for histone deacetylase inhibitors |
| Q52597611 | KAT3B-p300 and H3AcK18/H3AcK14 levels are prognostic markers for kidney ccRCC tumor aggressiveness and target of KAT inhibitor CPTH2. |
| Q36452936 | Live-cell studies of p300/CBP histone acetyltransferase activity and inhibition |
| Q37062105 | Lung cancer and its association with chronic obstructive pulmonary disease: update on nexus of epigenetics |
| Q48098684 | Lysine Acetylation Goes Global: From Epigenetics to Metabolism and Therapeutics. |
| Q99237713 | Lysine Acetyltransferase Inhibitors From Natural Sources |
| Q38085375 | Lysine acetyltransferases CBP and p300 as therapeutic targets in cognitive and neurodegenerative disorders. |
| Q38150711 | Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer |
| Q41896576 | Novel insights into histone modifiers in adipogenesis |
| Q50439440 | Nucleic acid-mimicking coordination polymer for label-free fluorescent activity assay of histone acetyltransferases. |
| Q37992020 | Ochratoxin a and mitotic disruption: mode of action analysis of renal tumor formation by ochratoxin A. |
| Q38843254 | PTEN activation through K163 acetylation by inhibiting HDAC6 contributes to tumour inhibition |
| Q38080414 | Perspectives on natural product epigenetic modulators in chemical biology and medicine. |
| Q41617155 | Phototrophy and starvation-based induction of autophagy upon removal of Gcn5-catalyzed acetylation of Atg7 in Magnaporthe oryzae |
| Q34472671 | Potential biological applications of bio-based anacardic acids and their derivatives |
| Q38345325 | Principles and problems of the electrophoretic mobility shift assay |
| Q36590549 | Purification of multiprotein histone acetyltransferase complexes |
| Q64054689 | Quantifying Tip60 (Kat5) stratifies breast cancer |
| Q37641967 | Quantitative Analysis and Discovery of Lysine and Arginine Modifications. |
| Q42323836 | Radiosensitizing effect of the histone acetyltransferase inhibitor anacardic acid on various mammalian cell lines. |
| Q35764015 | Redox regulation of genome stability by effects on gene expression, epigenetic pathways and DNA damage/repair. |
| Q58860078 | Rhodanine carboxylic acids as novel inhibitors of histone acetyltransferases |
| Q28831354 | Salicylate, diflunisal and their metabolites inhibit CBP/p300 and exhibit anticancer activity |
| Q39148603 | Selective inhibition of p300 HAT blocks cell cycle progression, induces cellular senescence, and inhibits the DNA damage response in melanoma cells. |
| Q51251801 | Site-Specific Acetyl Lysine Antibodies Reveal Differential Regulation of Histone Acetylation upon Kinase Inhibition. |
| Q34123380 | Small molecule inhibitors of histone acetyltransferases as epigenetic tools and drug candidates |
| Q37961728 | Small-molecule chromatin-modifying agents: therapeutic applications |
| Q34692024 | Small-molecule inhibitors of acetyltransferase p300 identified by high-throughput screening are potent anticancer agents. |
| Q41930037 | Sodium phenylbutyrate abrogates African swine fever virus replication by disrupting the virus-induced hypoacetylation status of histone H3K9/K14. |
| Q26314426 | Structure and Functional Diversity of GCN5-Related N-Acetyltransferases (GNAT) |
| Q40271872 | Structure-Activity Relationships on Cinnamoyl Derivatives as Inhibitors of p300 Histone Acetyltransferase. |
| Q90676091 | Sulforaphane and iberin are potent epigenetic modulators of histone acetylation and methylation in malignant melanoma |
| Q26741346 | Targeting cancer using KAT inhibitors to mimic lethal knockouts |
| Q37961798 | Targeting epigenetic networks with polypharmacology: a new avenue to tackle cancer |
| Q57712790 | Targeting transcription factor lysine acetylation in inflammatory airway diseases |
| Q26746703 | The Impact of External Factors on the Epigenome: In Utero and over Lifetime |
| Q38707912 | The bounty of nature for changing the cancer landscape |
| Q30383560 | The histone acetyltransferase p300 inhibitor C646 reduces pro-inflammatory gene expression and inhibits histone deacetylases. |
| Q26825332 | The role of posttranslational modifications in the assembly of stress granules |
| Q35842121 | The stability of histone acetyltransferase general control non-derepressible (Gcn) 5 is regulated by Cullin4-RING E3 ubiquitin ligase |
| Q38723116 | Therapeutics Targeting Protein Acetylation Perturb Latency of Human Viruses |
| Q34734222 | Three-dimensional collagen I promotes gemcitabine resistance in vitro in pancreatic cancer cells through HMGA2-dependent histone acetyltransferase expression |
| Q30437494 | Towards new approaches to disorders of fear and anxiety |
| Q37251585 | Trichostatin A, a histone deacetylase inhibitor suppresses NADPH Oxidase 4-Derived Redox Signalling and Angiogenesis |
| Q34137377 | Tuning acetylation levels with HAT activators: Therapeutic strategy in neurodegenerative diseases |
| Q34607095 | Use of epigenetic drugs in disease: an overview |
| Q33599508 | Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor |
| Q46530595 | Vitamin A upregulates matrix metalloproteinase-9 activity by murine myeloid dendritic cells through a nonclassical transcriptional mechanism |
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