scholarly article | Q13442814 |
P50 | author | K. Ravi Acharya | Q56451095 |
Jonathan R Davies | Q88168821 | ||
P2093 | author name string | Sai Man Liu | |
P2860 | cites work | Botulinum neurotoxin types B and E: purification, limited proteolysis by endoproteinase Glu-C and pepsin, and comparison of their identified cleaved sites relative to the three-dimensional structure of type A neurotoxin | Q43691688 |
C3 exoenzyme from Clostridium botulinum: structure of a tetragonal crystal form and a reassessment of NAD-induced flexure | Q44991874 | ||
Molecular characterization of a novel botulinum neurotoxin type H gene | Q45290850 | ||
A novel strain of Clostridium botulinum that produces type B and type H botulinum toxins | Q45345427 | ||
Botulinum neurotoxin G binds synaptotagmin-II in a mode similar to that of serotype B: tyrosine 1186 and lysine 1191 cause its lower affinity | Q45345429 | ||
Identification of the SV2 protein receptor-binding site of botulinum neurotoxin type E. | Q45364853 | ||
Characterization of the D/C mosaic neurotoxin produced by Clostridium botulinum associated with bovine botulism in Japan | Q46596535 | ||
Binding of Clostridium botulinum type C and D neurotoxins to ganglioside and phospholipid. Novel insights into the receptor for clostridial neurotoxins | Q46663715 | ||
Mosaic structures of neurotoxins produced from Clostridium botulinum types C and D organisms | Q46880568 | ||
Translocation of botulinum neurotoxin light chain protease through the heavy chain channel | Q46942366 | ||
Structural basis for the unique ganglioside and cell membrane recognition mechanism of botulinum neurotoxin DC. | Q47093993 | ||
High resolution crystal structures of Clostridium botulinum neurotoxin A3 and A4 binding domains. | Q47244161 | ||
Novel chimeras of botulinum neurotoxins A and E unveil contributions from the binding, translocation, and protease domains to their functional characteristics | Q47783055 | ||
Characterization of the functional activity of botulinum neurotoxin subtype B6. | Q47817058 | ||
Differential contribution of the residues in C-terminal half of the heavy chain of botulinum neurotoxin type B to its binding to the ganglioside GT1b and the synaptotagmin 2/GT1b complex | Q48327877 | ||
Thioredoxin and its reductase are present on synaptic vesicles, and their inhibition prevents the paralysis induced by botulinum neurotoxins. | Q48543733 | ||
Identification of a novel botulinum neurotoxin gene cluster in Enterococcus | Q50091489 | ||
Identification of a Botulinum Neurotoxin-like Toxin in a Commensal Strain of Enterococcus faecium. | Q50207264 | ||
Only the complex N559-glycan in the synaptic vesicle glycoprotein 2C mediates high affinity binding to botulinum neurotoxin serotype A1. | Q51505838 | ||
Uptake of botulinum neurotoxin into cultured neurons. | Q52095157 | ||
Crystal Structure of Botulinum Neurotoxin A2 in Complex with the Human Protein Receptor SV2C Reveals Plasticity in Receptor Binding. | Q52323614 | ||
Structural characterisation of the catalytic domain of botulinum neurotoxin X - high activity and unique substrate specificity. | Q52655358 | ||
Genomic insights into the evolution and ecology of botulinum neurotoxins. | Q52717433 | ||
A lipid-binding loop of botulinum neurotoxin serotypes B, DC and G is an essential feature to confer their exquisite potency. | Q52803571 | ||
Characterization of the neurotoxin produced by isolates associated with avian botulism. | Q54633890 | ||
Purification and Characterization of Recombinant Botulinum Neurotoxin Serotype FA, Also Known as Serotype H. | Q54983982 | ||
High resolution crystal structures of the receptor-binding domain of Clostridium botulinum neurotoxin serotypes A and FA. | Q55256497 | ||
Botulinum Neurotoxin F Subtypes Cleaving the VAMP-2 Q⁻K Peptide Bond Exhibit Unique Catalytic Properties and Substrate Specificities | Q58805104 | ||
Nicking of single chain Clostridium botulinum type A neurotoxin by an endogenous protease | Q69521812 | ||
Botulinum type A neurotoxin digested with pepsin yields 132, 97, 72, 45, 42, and 18 kD fragments | Q70477491 | ||
Binding of botulinum type B neurotoxin to Chinese hamster ovary cells transfected with rat synaptotagmin II cDNA | Q71660117 | ||
Botulinum neurotoxin A activity is dependent upon the presence of specific gangliosides in neuroblastoma cells expressing synaptotagmin I | Q74380537 | ||
Comparison of effects of botulinum toxin subtype A1 and A2 using twitch tension assay and rat grip strength test | Q82207656 | ||
Validity of botulinum neurotoxin serotype H | Q87661789 | ||
Synaptotagmin II and gangliosides bind independently with botulinum neurotoxin B but each restrains the other | Q87698566 | ||
SV2 mediates entry of tetanus neurotoxin into central neurons | Q21090499 | ||
Botulinal neurotoxins: revival of an old killer | Q23832313 | ||
Toxigenic clostridia | Q24616838 | ||
Genomes, neurotoxins and biology of Clostridium botulinum Group I and Group II | Q26853403 | ||
Structural analysis of the catalytic and binding sites of Clostridium botulinum neurotoxin B | Q27626220 | ||
Structural basis of cell surface receptor recognition by botulinum neurotoxin B | Q27643302 | ||
Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity | Q27643303 | ||
Crystal Structure of Botulinum Neurotoxin Type A in Complex with the Cell Surface Co-Receptor GT1b—Insight into the Toxin–Neuron Interaction | Q27651618 | ||
Domain organization in Clostridium botulinum neurotoxin type E is unique: its implication in faster translocation | Q27653311 | ||
Glycosylated SV2 and Gangliosides as Dual Receptors for Botulinum Neurotoxin Serotype F | Q27655649 | ||
Crystal Structure of the Botulinum Neurotoxin Type G Binding Domain: Insight into Cell Surface Binding | Q27660172 | ||
Structural Analysis of Botulinum Neurotoxin Type G Receptor Binding, | Q27662005 | ||
Botulinum neurotoxin serotype D attacks neurons via two carbohydrate-binding sites in a ganglioside-dependent manner | Q27664044 | ||
Identification of a Unique Ganglioside Binding Loop within Botulinum Neurotoxins C and D-SA, | Q27664131 | ||
Structural analysis of the receptor binding domain of botulinum neurotoxin serotype D | Q27664616 | ||
Crystal structure of the receptor binding domain of the botulinum C–D mosaic neurotoxin reveals potential roles of lysines 1118 and 1136 in membrane interactions | Q27666174 | ||
The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites | Q27667683 | ||
Novel Ganglioside-mediated Entry of Botulinum Neurotoxin Serotype D into Neurons | Q27668123 | ||
Unique Ganglioside Recognition Strategies for Clostridial Neurotoxins | Q27671814 | ||
Botulinum Neurotoxin Serotype C Associates with Dual Ganglioside Receptors to Facilitate Cell Entry | Q27673821 | ||
Structural insights into the functional role of the Hcn sub-domain of the receptor-binding domain of the botulinum neurotoxin mosaic serotype C/D | Q27677003 | ||
Structure of dual receptor binding to botulinum neurotoxin B | Q27678834 | ||
Crystal Structures of Botulinum Neurotoxin DC in Complex with Its Protein Receptors Synaptotagmin I and II | Q27679493 | ||
Structural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin A | Q27687569 | ||
Crystal structure of botulinum neurotoxin type A and implications for toxicity | Q27765727 | ||
Synaptotagmin: a Ca(2+) sensor that triggers exocytosis? | Q28208303 | ||
A complexin/synaptotagmin 1 switch controls fast synaptic vesicle exocytosis | Q28264748 | ||
Human synaptotagmin-II is not a high affinity receptor for botulinum neurotoxin B and G: increased therapeutic dosage and immunogenicity | Q28572057 | ||
The synaptic vesicle protein 2C mediates the uptake of botulinum neurotoxin A into phrenic nerves | Q28578304 | ||
"Inconvenient truths" in the pursuit of scientific knowledge and public health | Q28660966 | ||
The HCC-domain of botulinum neurotoxins A and B exhibits a singular ganglioside binding site displaying serotype specific carbohydrate interaction | Q31036598 | ||
Sequencing the botulinum neurotoxin gene and related genes in Clostridium botulinum type E strains reveals orfx3 and a novel type E neurotoxin subtype | Q33300918 | ||
Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4 and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within plasmids | Q33308728 | ||
Loss of the Synaptic Vesicle Protein SV2B results in reduced neurotransmission and altered synaptic vesicle protein expression in the retina. | Q33432742 | ||
Clostridial toxins as therapeutic agents: benefits of nature's most toxic proteins | Q33765977 | ||
Botulinum neurotoxin D-C uses synaptotagmin I and II as receptors, and human synaptotagmin II is not an effective receptor for type B, D-C and G toxins | Q33793263 | ||
Botulinum neurotoxin D uses synaptic vesicle protein SV2 and gangliosides as receptors | Q33869062 | ||
Draft Genome Sequence of Weissella oryzae SG25T, Isolated from Fermented Rice Grains | Q33949089 | ||
Two novel toxin variants revealed by whole-genome sequencing of 175 Clostridium botulinum type E strains | Q34261184 | ||
Clostridium and bacillus binary enterotoxins: bad for the bowels, and eukaryotic being. | Q34263384 | ||
Synaptotagmins: why so many? | Q34460901 | ||
Analysis of a unique Clostridium botulinum strain from the Southern hemisphere producing a novel type E botulinum neurotoxin subtype | Q34462614 | ||
Botulinum neurotoxin subtype A2 enters neuronal cells faster than subtype A1 | Q34583087 | ||
Genetic characterization and comparison of Clostridium botulinum isolates from botulism cases in Japan between 2006 and 2011. | Q34594221 | ||
Clostridium botulinum strain Af84 contains three neurotoxin gene clusters: bont/A2, bont/F4 and bont/F5. | Q34700141 | ||
An atypical outbreak of food-borne botulism due to Clostridium botulinum types B and E from ham. | Q34983207 | ||
Isolation and functional characterization of the novel Clostridium botulinum neurotoxin A8 subtype. | Q35058841 | ||
Unique ganglioside binding by botulinum neurotoxins C and D-SA | Q35207347 | ||
Identification of the protein receptor binding site of botulinum neurotoxins B and G proves the double-receptor concept. | Q35250681 | ||
Analysis of Clostridium botulinum serotype E strains by using multilocus sequence typing, amplified fragment length polymorphism, variable-number tandem-repeat analysis, and botulinum neurotoxin gene sequencing | Q35599226 | ||
Genetic diversity among Botulinum Neurotoxin-producing clostridial strains | Q35634548 | ||
Beltless translocation domain of botulinum neurotoxin A embodies a minimum ion-conductive channel | Q35693923 | ||
Phylogeny and taxonomy of the food-borne pathogen Clostridium botulinum and its neurotoxins | Q35831352 | ||
De novo subtype and strain identification of botulinum neurotoxin type B through toxin proteomics. | Q35843022 | ||
Nucleotide sequence of Clostridium botulinum C1 neurotoxin | Q35871888 | ||
Laboratory Investigation of the First Case of Botulism Caused by Clostridium butyricum Type E Toxin in the United States. | Q36066793 | ||
Botulinum neurotoxins B and E translocate at different rates and exhibit divergent responses to GT1b and low pH | Q36099792 | ||
Purification and characterization of a protease from Clostridium botulinum type A that nicks single-chain type A botulinum neurotoxin into the di-chain form | Q36162224 | ||
In vivo onset and duration of action varies for botulinum neurotoxin A subtypes 1-5. | Q36315520 | ||
Synaptotagmins I and II mediate entry of botulinum neurotoxin B into cells | Q36325534 | ||
Mechanism of botulinum neurotoxin B and G entry into hippocampal neurons | Q36639118 | ||
Glycosylated SV2A and SV2B mediate the entry of botulinum neurotoxin E into neurons. | Q36992893 | ||
N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A. | Q37276819 | ||
Receptor and substrate interactions of clostridial neurotoxins | Q37408530 | ||
Molecular characterization of Clostridium botulinum isolates from foodborne outbreaks in Thailand, 2010. | Q37521567 | ||
Type C botulism due to toxic feed affecting 52,000 farmed foxes and minks in Finland | Q37575869 | ||
Synaptotagmin 2 Is the Fast Ca2+ Sensor at a Central Inhibitory Synapse | Q37611626 | ||
Crystal structure of the BoNT/A2 receptor-binding domain in complex with the luminal domain of its neuronal receptor SV2C | Q37677078 | ||
Crystal Structure of the Receptor-Binding Domain of Botulinum Neurotoxin Type HA, Also Known as Type FA or H. | Q37727928 | ||
Botulinum neurotoxins: new questions arising from structural biology. | Q38256719 | ||
Glycans Confer Specificity to the Recognition of Ganglioside Receptors by Botulinum Neurotoxin A. | Q38289813 | ||
Evidence for direct binding of Clostridium botulinum type E derivative toxin and its fragments to gangliosides and free fatty acids | Q38350234 | ||
On the translocation of botulinum and tetanus neurotoxins across the membrane of acidic intracellular compartments. | Q38573906 | ||
Analysis of neurotoxin cluster genes in Clostridium botulinum strains producing botulinum neurotoxin serotype A subtypes | Q38607324 | ||
Differentiating Botulinum Neurotoxin-Producing Clostridia with a Simple, Multiplex PCR Assay | Q38667349 | ||
Structure, Function and Evolution of Clostridium botulinum C2 and C3 Toxins: Insight to Poultry and Veterinary Vaccines | Q39028709 | ||
Genetic analysis of type E botulinum toxin-producing Clostridium butyricum strains | Q39488386 | ||
Double anchorage to the membrane and intact inter-chain disulfide bond are required for the low pH induced entry of tetanus and botulinum neurotoxins into neurons. | Q39500669 | ||
Molecular cloning of the Clostridium botulinum structural gene encoding the type B neurotoxin and determination of its entire nucleotide sequence. | Q39894316 | ||
Crucial role of the disulfide bridge between botulinum neurotoxin light and heavy chains in protease translocation across membranes | Q40100085 | ||
SV2 is the protein receptor for botulinum neurotoxin A. | Q40303506 | ||
Entry of Botulinum Neurotoxin Subtypes A1 and A2 into Neurons | Q40442566 | ||
Inhibition of botulinum neurotoxins interchain disulfide bond reduction prevents the peripheral neuroparalysis of botulism. | Q40451664 | ||
Role of a Protease in Natural Activation of Clostridium botulinum Neurotoxin | Q40913922 | ||
Engineered botulinum neurotoxin B with improved efficacy for targeting human receptors | Q40971832 | ||
Identification and characterization of a novel botulinum neurotoxin. | Q41245604 | ||
Genomic characterization of Italian Clostridium botulinum group I strains | Q41407289 | ||
Toxin detection in patients' sera by mass spectrometry during two outbreaks of type A Botulism in France. | Q41636038 | ||
Botulinum neurotoxin homologs in non-Clostridium species. | Q41648666 | ||
Sequence diversity of genes encoding botulinum neurotoxin type F. | Q41773499 | ||
Neurotoxin gene clusters in Clostridium botulinum type Ab strains. | Q42244103 | ||
The first non Clostridial botulinum-like toxin cleaves VAMP within the juxtamembrane domain | Q42408273 | ||
Draft Genome Sequence of Bivalent Clostridium botulinum Strain IBCA10-7060, Encoding Botulinum Neurotoxin B and a New FA Mosaic Type | Q42580371 | ||
Characterization of botulinum type A neurotoxin gene: delineation of the N-terminal encoding region | Q42644816 | ||
Novel clostridium botulinum toxin and dual use research of concern issues | Q42773993 | ||
Novel Clostridium botulinum toxin gene arrangement with subtype A5 and partial subtype B3 botulinum neurotoxin genes | Q43097153 | ||
Botulinum neurotoxins C, E and F bind gangliosides via a conserved binding site prior to stimulation-dependent uptake with botulinum neurotoxin F utilising the three isoforms of SV2 as second receptor | Q43299518 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 10 | |
P407 | language of work or name | English | Q1860 |
P577 | publication date | 2018-10-20 | |
P1433 | published in | Toxins | Q15724569 |
P1476 | title | Variations in the Botulinum Neurotoxin Binding Domain and the Potential for Novel Therapeutics | |
P478 | volume | 10 |