Combination immunotherapy and radiation therapy strategies for pancreatic cancer-targeting multiple steps in the cancer immunity cycle

Combination immunotherapy and radiation therapy strategies for pancreatic cancer-targeting multiple steps in the cancer immunity cycle is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.21037/JGO.2018.05.16
P932PMC publication ID6286952
P698PubMed publication ID30603120

P50authorIgnacio Garrido-LagunaQ71791712
P2093author name stringConan Kinsey
Anna Torgeson
Shane Lloyd
Snehal Gajiwala
P2860cites workModern Radiotherapy Concepts and the Impact of Radiation on Immune ActivationQ26744490
Sipuleucel-T immunotherapy for castration-resistant prostate cancerQ27860648
The abscopal effect of local radiotherapy: using immunotherapy to make a rare event clinically relevantQ28081732
Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenaseQ28204166
Idiotype vaccination as consolidation therapy: time for integration into standard of care for follicular lymphoma?Q43053502
Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer.Q46111623
Adjuvant Nivolumab versus Ipilimumab in Resected Stage III or IV MelanomaQ47551890
Real-Time Genomic Profiling of Pancreatic Ductal Adenocarcinoma: Potential Actionability and Correlation with Clinical PhenotypeQ48013101
Pembrolizumab for the Treatment of Advanced Salivary Gland Carcinoma: Findings of the Phase 1b KEYNOTE-028 StudyQ49925686
Pembrolizumab as first-line therapy for metastatic non-small-cell lung cancerQ49959323
Prevalence of FOXP3+ regulatory T cells increases during the progression of pancreatic ductal adenocarcinoma and its premalignant lesions.Q51803685
Clinical significance and therapeutic potential of the programmed death-1 ligand/programmed death-1 pathway in human pancreatic cancer.Q54287306
The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor zeta-chain and induce a regulatory phenotype in naive T cellsQ56902123
Die Rolle der Strahlentherapie bei der Induktion von Antitumor-ImmunantwortenQ61893824
Clinical roles of increased populations of Foxp3+CD4+ T cells in peripheral blood from advanced pancreatic cancer patientsQ79323463
B7-H1 up-regulated expression in human pancreatic carcinoma tissue associates with tumor progressionQ80890589
Abscopal effect in a patient with melanomaQ84201850
Ionizing radiation inhibition of distant untreated tumors (abscopal effect) is immune mediatedQ28245528
The Galalpha1,3Galbeta1,4GlcNAc-R (alpha-Gal) epitope: a carbohydrate of unique evolution and clinical relevanceQ28755302
Cancer immunotherapy via dendritic cellsQ29615444
Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabineQ29616728
Immunologic correlates of the abscopal effect in a patient with melanomaQ29620334
Targeting tumour-associated macrophages with CCR2 inhibition in combination with FOLFIRINOX in patients with borderline resectable and locally advanced pancreatic cancer: a single-centre, open-label, dose-finding, non-randomised, phase 1b trial.Q33609699
Immuno-oncology: understanding the function and dysfunction of the immune system in cancerQ33859814
Abscopal effects of radiotherapy on advanced melanoma patients who progressed after ipilimumab immunotherapy.Q33930593
CSF1/CSF1R blockade reprograms tumor-infiltrating macrophages and improves response to T-cell checkpoint immunotherapy in pancreatic cancer models.Q34279134
Elevated myeloid-derived suppressor cells in pancreatic, esophageal and gastric cancer are an independent prognostic factor and are associated with significant elevation of the Th2 cytokine interleukin-13.Q35222367
Inflammatory cells contribute to the generation of an angiogenic phenotype in pancreatic ductal adenocarcinomaQ35587710
IDO and tolerance to tumorsQ35628246
Tumor-associated transforming growth factor-beta and interleukin-10 contribute to a systemic Th2 immune phenotype in pancreatic carcinoma patientsQ35787792
PD-1/PD-L1 inhibitors.Q35893753
The controversial abscopal effectQ36143531
CD40 Stimulation Obviates Innate Sensors and Drives T Cell Immunity in CancerQ37029731
Fractionated but not single-dose radiotherapy induces an immune-mediated abscopal effect when combined with anti-CTLA-4 antibodyQ37351567
Potential targets for pancreatic cancer immunotherapeuticsQ37861220
Induction of abscopal anti-tumor immunity and immunogenic tumor cell death by ionizing irradiation - implications for cancer therapies.Q37993183
Role of the immune system in pancreatic cancer progression and immune modulating treatment strategies.Q38169428
Effect of Chemoradiotherapy vs Chemotherapy on Survival in Patients With Locally Advanced Pancreatic Cancer Controlled After 4 Months of Gemcitabine With or Without Erlotinib: The LAP07 Randomized Clinical Trial.Q38393038
Adjuvant ipilimumab versus placebo after complete resection of high-risk stage III melanoma (EORTC 18071): a randomised, double-blind, phase 3 trialQ38404655
Addition of algenpantucel-L immunotherapy to standard adjuvant therapy for pancreatic cancer: a phase 2 studyQ38459890
Changing the course of pancreatic cancer--Focus on recent translational advancesQ38753998
MAP Kinase Inhibition Promotes T Cell and Anti-tumor Activity in Combination with PD-L1 Checkpoint BlockadeQ38788877
The Abscopal Effect of Radiation Therapy: What Is It and How Can We Use It in Breast Cancer?Q38875105
PD-1 Restrains Radiotherapy-Induced Abscopal Effect.Q38907646
Pembrolizumab versus Chemotherapy for PD-L1-Positive Non-Small-Cell Lung CancerQ38975751
Cancer Statistics, 2017.Q39038674
Phase III randomized trial of patient-specific vaccination for previously untreated patients with follicular lymphoma in first complete remission: protocol summary and interim reportQ39130681
Projecting cancer incidence and deaths to 2030: the unexpected burden of thyroid, liver, and pancreas cancers in the United StatesQ39190004
Prolonged Survival in Stage III Melanoma with Ipilimumab Adjuvant TherapyQ39311439
Pancreatic cancer: Update on immunotherapies and algenpantucel-L.Q40261599
CD4+CD25+ regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curativeQ40591372
One percent of human circulating B lymphocytes are capable of producing the natural anti-Gal antibodyQ41521078
Local radiotherapy and granulocyte-macrophage colony-stimulating factor to generate abscopal responses in patients with metastatic solid tumours: a proof-of-principle trial.Q41653193
Priming the pancreatic cancer tumor microenvironment for checkpoint-inhibitor immunotherapyQ42118954
Overcoming immunosuppression as a new immunotherapeutic approach against pancreatic cancerQ42848515
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectgastroenterologyQ120569
immunotherapyQ1427096
P304page(s)1014-1026
P577publication date2018-12-01
P1433published inJournal of gastrointestinal oncologyQ26842467
P1476titleCombination immunotherapy and radiation therapy strategies for pancreatic cancer-targeting multiple steps in the cancer immunity cycle
P478volume9

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cites work (P2860)
Q92600987Irreversible Electroporation Combined with Checkpoint Blockade and TLR7 Stimulation Induces Antitumor Immunity in a Murine Pancreatic Cancer Model
Q94602728Relationship between IL-10 and PD-L1 in esophageal carcinoma tissues and IL-10 down-regulates PD-L1 expression via Met signaling pathway
Q98159678Relationship between IL10 and PD-L1 in Liver Hepatocellular Carcinoma Tissue and Cell Lines
Q64967557The Combination of Stereotactic Body Radiation Therapy and Immunotherapy in Primary Liver Tumors.
Q92627680Use of a Linear Accelerator for Conducting In Vitro Radiobiology Experiments

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