Alternate aerosol and systemic immunisation with a recombinant viral vector for tuberculosis, MVA85A: A phase I randomised controlled trial

scientific article published on 30 April 2019

Alternate aerosol and systemic immunisation with a recombinant viral vector for tuberculosis, MVA85A: A phase I randomised controlled trial is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PMED.1002790
P932PMC publication ID6490884
P698PubMed publication ID31039172

P50authorHelen McShaneQ58870907
Lisa StockdaleQ87705741
Michael RisteQ90313329
Zita-Rose Manjaly ThomasQ91643221
Alison M. LawrieQ109926029
P2093author name stringMorven Wilkie
Iman Satti
Stephanie A Harris
Ali Hamidi
Alice Minhinnick
Raquel Lopez Ramon
Samantha Vermaak
Julia L Marshall
Henry Bettinson
P2860cites workThe efficacy of bacillus Calmette-Guérin vaccination of newborns and infants in the prevention of tuberculosis: meta-analyses of the published literatureQ52877396
Prevention of M. tuberculosis Infection with H4:IC31 Vaccine or BCG Revaccination.Q55617820
Phase 2b Controlled Trial of M72/AS01 Vaccine to Prevent TuberculosisQ57069957
IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challengeQ58518610
Immunization Against Measles by AerosolQ70272393
Hypersensitivity Pneumonitis: A Comprehensive ReviewQ26796700
Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania majorQ29619125
Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trialQ29620144
Comparing the safety and immunogenicity of a candidate TB vaccine MVA85A administered by intramuscular and intradermal deliveryQ33603206
Safety and immunogenicity of a candidate tuberculosis vaccine MVA85A delivered by aerosol in BCG-vaccinated healthy adults: a phase 1, double-blind, randomised controlled trial.Q34259027
Cough aerosols of Mycobacterium tuberculosis predict new infection: a household contact studyQ34322008
Efficacy of BCG vaccine in the prevention of tuberculosis. Meta-analysis of the published literatureQ34349749
Recombinant modified vaccinia virus Ankara expressing antigen 85A boosts BCG-primed and naturally acquired antimycobacterial immunity in humansQ34361636
Intranasal boosting with an adenovirus-vectored vaccine markedly enhances protection by parenteral Mycobacterium bovis BCG immunization against pulmonary tuberculosisQ34975770
Cell-mediated immune responses in tuberculosisQ34982062
A "prime-pull" vaccine strategy has a modest effect on local and systemic antibody responses to HIV gp140 in miceQ35049110
New aspects of hypersensitivity pneumonitis.Q35865633
Evaluation of the Immunogenicity of Mycobacterium bovis BCG Delivered by Aerosol to the Lungs of MacaquesQ35998753
Characterization of the Antigen-Specific CD4(+) T Cell Response Induced by Prime-Boost Strategies with CAF01 and CpG Adjuvants Administered by the Intranasal and Subcutaneous RoutesQ36002296
A vaccine strategy that protects against genital herpes by establishing local memory T cellsQ36403540
T-cell activation is an immune correlate of risk in BCG vaccinated infantsQ36799172
Evaluation of the safety and immunogenicity of a candidate tuberculosis vaccine, MVA85A, delivered by aerosol to the lungs of macaquesQ36826315
Immunogenicity and safety of aerosolized measles vaccine: systematic review and meta-analysisQ37032973
Hypersensitivity pneumonitis: insights in diagnosis and pathobiologyQ38017165
Chronic hypersensitivity pneumonitis: important considerations in the work-up of this fibrotic lung diseaseQ38316859
Alternative routes of measles immunization: a reviewQ38958647
Vaccine-induced Th17 cells are established as resident memory cells in the lung and promote local IgA responsesQ40726914
THE MOST RECENT EXPERIMENTS WITH "BACILLE CALMETTE GUERIN".Q40845874
Specific T cell frequency and cytokine expression profile do not correlate with protection against tuberculosis after bacillus Calmette-Guérin vaccination of newbornsQ41775340
Control of chronic mycobacterium tuberculosis infection by CD4 KLRG1- IL-2-secreting central memory cellsQ42262934
Enhanced immunogenicity and protective efficacy against Mycobacterium tuberculosis of bacille Calmette-Guérin vaccine using mucosal administration and boosting with a recombinant modified vaccinia virus AnkaraQ45722508
BCG vaccination and the EPI.Q46272168
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue4
P407language of work or nameEnglishQ1860
P921main subjecttuberculosisQ12204
phase I clinical trialQ5452194
P304page(s)e1002790
P577publication date2019-04-30
P1433published inPLOS MEDICINEQ1686921
P1476titleAlternate aerosol and systemic immunisation with a recombinant viral vector for tuberculosis, MVA85A: A phase I randomised controlled trial
P478volume16

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cites work (P2860)
Q64080155Addressing critical needs in the fight to end tuberculosis with innovative tools and strategies
Q97553095Emerging trends in inhaled drug delivery
Q92645553Insights and challenges in tuberculosis vaccine development
Q92246549Mucosal delivery of tuberculosis vaccines: a review of current approaches and challenges
Q98465670Targeting Unconventional Host Components for Vaccination-Induced Protection Against TB
Q89514589The status of tuberculosis vaccine development
Q89533499Toll like-receptor agonist Pam3Cys modulates the immunogenicity of liposomes containing the tuberculosis vaccine candidate H56
Q90345218Vaccination Against Tuberculosis: Revamping BCG by Molecular Genetics Guided by Immunology
Q100751549Vaccine strategies for the Mtb/HIV copandemic

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