Deletion of the DEF1 gene does not confer UV-immutability but frequently leads to self-diploidization in yeast Saccharomyces cerevisiae

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Deletion of the DEF1 gene does not confer UV-immutability but frequently leads to self-diploidization in yeast Saccharomyces cerevisiae is …
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scholarly articleQ13442814

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P356DOI10.1016/J.DNAREP.2018.08.026
P932PMC publication ID6173828
P698PubMed publication ID30172224

P2093author name stringY I Pavlov
E I Stepchenkova
A A Shiriaeva
P2860cites workEukaryotic DNA polymerase ζQ27011365
Def1 promotes the degradation of Pol3 for polymerase exchange to occur during DNA-damage--induced mutagenesis in Saccharomyces cerevisiaeQ27930388
A Rad26-Def1 complex coordinates repair and RNA pol II proteolysis in response to DNA damageQ27937572
Systematic identification of pathways that couple cell growth and division in yeastQ27939933
Novel roles for selected genes in meiotic DNA processingQ27940367
DNA Polymerase δ and ζ Switch by Sharing Accessory Subunits of DNA Polymerase δQ28263318
In vivo consequences of putative active site mutations in yeast DNA polymerases alpha, epsilon, delta, and zetaQ28354217
Genome-wide mutation avalanches induced in diploid yeast cells by a base analog or an APOBEC deaminaseQ28536837
Proteomic screening for amyloid proteinsQ28542935
A novel variant of DNA polymerase ζ, Rev3ΔC, highlights differential regulation of Pol32 as a subunit of polymerase δ versus ζ in Saccharomyces cerevisiaeQ28652503
Eukaryotic translesion synthesis DNA polymerases: specificity of structure and functionQ29617871
Genomic convergence toward diploidy in Saccharomyces cerevisiaeQ33258468
DNA polymerase zeta (pol zeta) in higher eukaryotesQ34729967
The property of DNA polymerase zeta: REV7 is a putative protein involved in translesion DNA synthesis and cell cycle controlQ35013042
Identification of Saccharomyces cerevisiae Genes Whose Deletion Causes Synthetic Effects in Cells with Reduced Levels of the Nuclear Pif1 DNA HelicaseQ36383222
Modulation of mutagenesis in eukaryotes by DNA replication fork dynamics and quality of nucleotide poolsQ37483304
Pif1 helicase and Polδ promote recombination-coupled DNA synthesis via bubble migration.Q37558760
Gene copy-number alterations: a cost-benefit analysisQ38078490
Distinct mechanisms of mutant huntingtin toxicity in different yeast strains.Q39133029
Translesion DNA polymerases in eukaryotes: what makes them tick?Q39171293
Improved flow cytometric analysis of the budding yeast cell cycle.Q44215106
Saccharomyces cerevisiae deletion strains with complex DNA content profiles.Q44301066
Dependency of Heterochromatin Domains on Replication Factors.Q47350699
Proteomic identification of histone post-translational modifications and proteins enriched at a DNA double-strand breakQ47445796
Recombination Is Responsible for the Increased Recovery of Drug-Resistant Mutants with Hypermutated Genomes in Resting Yeast Diploids Expressing APOBEC Deaminases.Q49388555
Def1 and Dst1 play distinct roles in repair of AP lesions in highly transcribed genomic regionsQ50994474
Spontaneous Changes in Ploidy Are Common in YeastQ51149794
Defect of Fe-S cluster binding by DNA polymerase δ in yeast suppresses UV-induced mutagenesis, but enhances DNA polymerase ζ - dependent spontaneous mutagenesisQ51228039
Restricted pleiotropy facilitates mutational erosion of major life-history traitsQ54708052
Adaptive genome duplication affects patterns of molecular evolution in Saccharomyces cerevisiae.Q55339992
[Mechanism of mutant induction in the ade2 gene of diploid Saccharomyces cerevisiae yeasts by ultraviolet rays]Q70160133
Mutability of LYS2 gene in diploid Saccharomyces yeasts. II. Frequency of mutants induced by 6-N-hydroxylaminopurine and propiolactoneQ70252176
Genetic side effects accompanying gene targeting in yeast: the influence of short heterologous terminiQ80397218
Iron-Sulfur Clusters in DNA Polymerases and Primases of EukaryotesQ88626544
P407language of work or nameEnglishQ1860
P921main subjectploidyQ118406
Saccharomyces cerevisiaeQ719725
DEF1Q27544682
P304page(s)49-54
P577publication date2018-10-01
P1433published inDNA RepairQ3894086
P1476titleDeletion of the DEF1 gene does not confer UV-immutability but frequently leads to self-diploidization in yeast Saccharomyces cerevisiae
P478volume70