CV-2619 protects cultured astrocytes against reperfusion injury via nerve growth factor production

scientific article published on 01 October 2000

CV-2619 protects cultured astrocytes against reperfusion injury via nerve growth factor production is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0014-2999(00)00701-9
P698PubMed publication ID11040339

P2093author name stringMori K
Lee E
Yoshida T
Matsuda T
Baba A
Takuma K
Kishi T
P2860cites workNGF and the treatment of Alzheimer's diseaseQ34347795
A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer diseaseQ35166007
Neuronal and glial apoptosis after traumatic spinal cord injury.Q36868349
Radical AGEing in Alzheimer's diseaseQ40542915
Idebenone. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in age-related cognitive disordersQ40644109
Astrocytes: form, functions, and roles in diseaseQ40762453
Hydrogen peroxide mediates amyloid beta protein toxicityQ41460857
Na(+)-Ca2+ exchanger: physiology and pharmacology.Q41508961
Nerve growth factor promotes survival of septal cholinergic neurons after fimbrial transectionsQ42525515
Stimulation of nerve growth factor synthesis/secretion by 1,4-benzoquinone and its derivatives in cultured mouse astroglial cellsQ43992105
Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly stateQ44689258
Oral administration of idebenone induces nerve growth factor in the brain and improves learning and memory in basal forebrain-lesioned ratsQ48146849
Oxidative stress induces apoptosis in embryonic cortical neurons.Q48226359
Protective effects of idebenone and alpha-tocopherol on beta-amyloid-(1-42)-induced learning and memory deficits in rats: implication of oxidative stress in beta-amyloid-induced neurotoxicity in vivoQ48284615
Idebenone protects hippocampal neurons against amyloid beta-peptide-induced neurotoxicity in rat primary culturesQ48335946
Selective glial vulnerability following transient global ischemia in rat brainQ48463130
Inhibition of lipid peroxidation by a novel compound (CV-2619) in brain mitochondria and mode of action of the inhibitionQ48588909
NGF-Mediated increase of choline acetyltransferase (ChAT) in the neonatal rat forebrain: Evidence for a physiological role of NGF in the brain?Q48792920
Heat shock protects cultured rat astrocytes in a model of reperfusion injuryQ48892096
Evidence for an NGF-induced autocrine neurotrophic potential of glial cells in nervous system development.Q53016027
Oral administration of idebenone, a stimulator of NGF synthesis, recovers reduced NGF content in aged rat brain.Q53208474
Effects of idebenone on neurological deficits following cerebrovascular lesions in stroke-prone spontaneously hypertensive rats.Q54109843
Effects of idebenone on neurological deficits, local cerebral blood flow, and energy metabolism in rats with experimental cerebral ischemiaQ69690850
Chronic intraventricular injections of nerve growth factor elevate hippocampal choline acetyltransferase activity in adult rats with partial septo-hippocampal lesionsQ71270737
Involvement of Na+-Ca2+ exchanger in reperfusion-induced delayed cell death of cultured rat astrocytesQ71354094
Cultured rat astrocytes possess Na(+)-Ca2+ exchangerQ72630595
Intracellular ascorbic acid inhibits the Na(+)-Ca2+ exchanger in cultured rat astrocytesQ72632390
Apoptosis in Ca2 + reperfusion injury of cultured astrocytes: roles of reactive oxygen species and NF-kappaB activationQ73265113
T-588 inhibits astrocyte apoptosis via mitogen-activated protein kinase signal pathwayQ73943216
Involvement of calcineurin in Ca2+ paradox-like injury of cultured rat astrocytesQ74509768
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectastrocyteQ502961
reperfusion injuryQ1413991
P304page(s)333-339
P577publication date2000-10-01
P1433published inEuropean Journal of PharmacologyQ1376712
P1476titleCV-2619 protects cultured astrocytes against reperfusion injury via nerve growth factor production
P478volume406

Reverse relations

cites work (P2860)
Q44077103Heat shock inhibits hydrogen peroxide-induced apoptosis in cultured astrocytes
Q28343913Ibudilast attenuates astrocyte apoptosis via cyclic GMP signalling pathway in an in vitro reperfusion model
Q34108909Idebenone increases mitochondrial complex I activity in fibroblasts from LHON patients while producing contradictory effects on respiration.
Q28741474NQO1-dependent redox cycling of idebenone: effects on cellular redox potential and energy levels
Q30497951Quantitative automated microscopy (QuAM) elucidates growth factor specific signalling in pain sensitization

Search more.