| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Nerea Osinalde | |
| Ugo Mayor | |||
| Juanma Ramirez | |||
| Cristina Garcia-Barcena | |||
| P2860 | cites work | RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination | Q22010577 |
| Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53 | Q22253350 | ||
| The E3 ubiquitin-ligase HACE1 catalyzes the ubiquitylation of active Rac1 | Q24294840 | ||
| UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids | Q24300880 | ||
| Solution Structure of the Hdm2 C2H2C4 RING, a Domain Critical for Ubiquitination of p53 | Q57078209 | ||
| The U box is a modified RING finger — a common domain in ubiquitination | Q57263070 | ||
| The E3 ubiquitin ligase TRIM25 regulates adipocyte differentiation via proteasome-mediated degradation of PPARγ | Q57462658 | ||
| Impaired proteostasis in rare neurological diseases | Q57807035 | ||
| Loss of the E3 ubiquitin ligase MKRN1 represses diet-induced metabolic syndrome through AMPK activation | Q58708227 | ||
| Parkin negatively regulates the antiviral signaling pathway by targeting TRAF3 for degradation | Q59358722 | ||
| Analysis of the Zn-Binding Domains of TRIM32, the E3 Ubiquitin Ligase Mutated in Limb Girdle Muscular Dystrophy 2H | Q64084220 | ||
| The p53-associated protein MDM2 contains a newly characterized zinc-binding domain called the RING finger | Q72100609 | ||
| The RING finger of c-Cbl mediates desensitization of the epidermal growth factor receptor | Q78069495 | ||
| Types of Ubiquitin Ligases | Q89063966 | ||
| Syntaphilin Ubiquitination Regulates Mitochondrial Dynamics and Tumor Cell Movements | Q89093378 | ||
| Phosphorylation of IRS4 by CK1γ2 promotes its degradation by CHIP through the ubiquitin/lysosome pathway | Q90352966 | ||
| A serine in the first transmembrane domain of the human E3 ubiquitin ligase MARCH9 is critical for down-regulation of its protein substrates | Q90560557 | ||
| HERC2 is an E3 ligase that targets BRCA1 for degradation. | Q53312505 | ||
| Lotus japonicus E3 ligase SEVEN IN ABSENTIA4 destabilizes the symbiosis receptor-like kinase SYMRK and negatively regulates rhizobial infection. | Q54514958 | ||
| TRIM37 defective in mulibrey nanism is a novel RING finger ubiquitin E3 ligase | Q24301759 | ||
| Role of histone H2A ubiquitination in Polycomb silencing | Q24305090 | ||
| RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites | Q24306486 | ||
| WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome | Q24563029 | ||
| RING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination | Q26850008 | ||
| Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases | Q27626747 | ||
| Solution structure of a Nedd4 WW domain-ENaC peptide complex | Q27631393 | ||
| Structure of a BRCA1-BARD1 heterodimeric RING-RING complex | Q27635007 | ||
| Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans | Q27649717 | ||
| Insights into Ubiquitin Transfer Cascades from a Structure of a UbcH5B∼Ubiquitin-HECTNEDD4L Complex | Q27658921 | ||
| RING domain dimerization is essential for RNF4 function | Q27663855 | ||
| Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis | Q27670947 | ||
| BIRC7–E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer | Q27671574 | ||
| Kinetic, Thermodynamic, and Structural Characterizations of the Association between Nrf2-DLGex Degron and Keap1 | Q27681060 | ||
| Structural insights into the TRIM family of ubiquitin E3 ligases | Q27683218 | ||
| Regulation of ubiquitin transfer by XIAP, a dimeric RING E3 ligase | Q27683623 | ||
| RING domain E3 ubiquitin ligases | Q27860546 | ||
| Mechanisms underlying ubiquitination | Q27860656 | ||
| The ubiquitin system | Q27860803 | ||
| Yeast DNA repair proteins Rad6 and Rad18 form a heterodimer that has ubiquitin conjugating, DNA binding, and ATP hydrolytic activities | Q27938794 | ||
| RNF144A, an E3 ubiquitin ligase for DNA-PKcs, promotes apoptosis during DNA damage | Q28116209 | ||
| The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase | Q28145635 | ||
| A novel cysteine-rich sequence motif | Q28264720 | ||
| The ubiquitin code | Q28265104 | ||
| Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing | Q28287373 | ||
| The E3 ubiquitin-ligase Bmi1/Ring1A controls the proteasomal degradation of Top2alpha cleavage complex - a potentially new drug target | Q28472102 | ||
| Autoubiquitylation of the V(D)J recombinase protein RAG1 | Q28508279 | ||
| The ability of TRIM3 to induce growth arrest depends on RING-dependent E3 ligase activity | Q28587814 | ||
| Functional regulation of FEZ1 by the U-box-type ubiquitin ligase E4B contributes to neuritogenesis | Q28593080 | ||
| Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization | Q29615622 | ||
| Ubiquitin Ligases: Structure, Function, and Regulation. | Q39219103 | ||
| Direct and indirect control of mitogen-activated protein kinase pathway-associated components, BRAP/IMP E3 ubiquitin ligase and CRAF/RAF1 kinase, by the deubiquitylating enzyme USP15. | Q39252412 | ||
| Dynamic ubiquitin signaling in cell cycle regulation. | Q39419310 | ||
| CHFR functions as a ubiquitin ligase for HLTF to regulate its stability and functions | Q39715347 | ||
| The ubiquitin E3 ligase TRIM31 promotes aggregation and activation of the signaling adaptor MAVS through Lys63-linked polyubiquitination | Q39757179 | ||
| Nedd4-2 catalyzes ubiquitination and degradation of cell surface ENaC. | Q40133019 | ||
| Asymmetric nature of two subunits of RAD18, a RING-type ubiquitin ligase E3, in the human RAD6A-RAD18 ternary complex. | Q40898008 | ||
| The E3 ubiquitin ligase AMFR and INSIG1 bridge the activation of TBK1 kinase by modifying the adaptor STING. | Q41590212 | ||
| The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension. | Q41774507 | ||
| The Prp19 U-box crystal structure suggests a common dimeric architecture for a class of oligomeric E3 ubiquitin ligases | Q41817040 | ||
| Ubiquitination-deubiquitination by the TRIM27-USP7 complex regulates tumor necrosis factor alpha-induced apoptosis | Q41867665 | ||
| Zinc Binding Properties of Engineered RING Finger Domain of Arkadia E3 Ubiquitin Ligase | Q41945238 | ||
| A conformational switch regulates the ubiquitin ligase HUWE1. | Q42321543 | ||
| Structural analysis of MDM2 RING separates degradation from regulation of p53 transcription activity. | Q42510354 | ||
| A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase | Q42682536 | ||
| TRIM37, a novel E3 ligase for PEX5-mediated peroxisomal matrix protein import. | Q44453670 | ||
| Ube3a, the E3 ubiquitin ligase causing Angelman syndrome and linked to autism, regulates protein homeostasis through the proteasomal shuttle Rpn10. | Q47070856 | ||
| Parkin targets HIF-1α for ubiquitination and degradation to inhibit breast tumor progression. | Q47132104 | ||
| Nuclear RNF2 inhibits interferon function by promoting K33-linked STAT1 disassociation from DNA. | Q47291958 | ||
| The E3 Ligase RING1 Targets p53 for Degradation and Promotes Cancer Cell Proliferation and Survival. | Q47350725 | ||
| ARIH2 Ubiquitinates NLRP3 and Negatively Regulates NLRP3 Inflammasome Activation in Macrophages. | Q47578909 | ||
| Cell cycle-regulated ubiquitination of tankyrase 1 by RNF8 and ABRO1/BRCC36 controls the timing of sister telomere resolution | Q48137760 | ||
| Inactivation of the MDM2 RING domain enhances p53 transcriptional activity in mice | Q50083521 | ||
| A Comprehensive Atlas of E3 Ubiquitin Ligase Mutations in Neurological Disorders | Q50329951 | ||
| ??? | Q64860635 | ||
| Physiological functions of the HECT family of ubiquitin ligases | Q29617293 | ||
| Substrate targeting in the ubiquitin system | Q33641408 | ||
| E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP. | Q33861394 | ||
| Functional communication between endogenous BRCA1 and its partner, BARD1, during Xenopus laevis development | Q33946999 | ||
| RNF2 is recruited by WASH to ubiquitinate AMBRA1 leading to downregulation of autophagy | Q34008456 | ||
| Identification of a ubiquitin-protein ligase subunit within the CCR4-NOT transcription repressor complex | Q34112326 | ||
| Mammalian HECT ubiquitin-protein ligases: biological and pathophysiological aspects | Q34336329 | ||
| Ubiquitin signaling: extreme conservation as a source of diversity | Q34341547 | ||
| Downregulation of cell surface receptors by the K3 family of viral and cellular ubiquitin E3 ligases. | Q34453408 | ||
| MARCH-IX mediates ubiquitination and downregulation of ICAM-1. | Q34591916 | ||
| Lysine 63-linked TANK-binding kinase 1 ubiquitination by mindbomb E3 ubiquitin protein ligase 2 is mediated by the mitochondrial antiviral signaling protein | Q34593916 | ||
| Ubiquitin in motion: structural studies of the ubiquitin-conjugating enzyme∼ubiquitin conjugate | Q34666396 | ||
| The E3 ubiquitin ligase RAD18 regulates ubiquitylation and chromatin loading of FANCD2 and FANCI | Q35029423 | ||
| The E3 ubiquitin ligase ARIH1 protects against genotoxic stress by initiating a 4EHP-mediated mRNA translation arrest. | Q35165148 | ||
| Contribution of E3-ubiquitin ligase activity to HIV-1 restriction by TRIM5alpha(rh): structure of the RING domain of TRIM5alpha | Q35192942 | ||
| The E3 ubiquitin ligase Trim7 mediates c-Jun/AP-1 activation by Ras signalling | Q35400332 | ||
| The Mdm2 RING domain C-terminus is required for supramolecular assembly and ubiquitin ligase activity | Q35610627 | ||
| N-terminal ubiquitination: more protein substrates join in. | Q35727083 | ||
| Estrogen receptor alpha is a putative substrate for the BRCA1 ubiquitin ligase | Q35749504 | ||
| Cancer-predisposing mutations within the RING domain of BRCA1: loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity | Q35865833 | ||
| The MLLE domain of the ubiquitin ligase UBR5 binds to its catalytic domain to regulate substrate binding | Q36050050 | ||
| The E3 ubiquitin ligase MARCH8 negatively regulates IL-1β-induced NF-κB activation by targeting the IL1RAP coreceptor for ubiquitination and degradation | Q36212969 | ||
| Structure of an E3:E2~Ub complex reveals an allosteric mechanism shared among RING/U-box ligases. | Q36291328 | ||
| The ubiquitin ligase HERC3 attenuates NF-κB-dependent transcription independently of its enzymatic activity by delivering the RelA subunit for degradation | Q36676501 | ||
| Activation of UbcH5c~Ub is the result of a shift in interdomain motions of the conjugate bound to U-box E3 ligase E4B. | Q36882621 | ||
| The MID1 E3 ligase catalyzes the polyubiquitination of Alpha4 (α4), a regulatory subunit of protein phosphatase 2A (PP2A): novel insights into MID1-mediated regulation of PP2A. | Q37175200 | ||
| The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein | Q37187752 | ||
| Smurf1-mediated Lys29-linked nonproteolytic polyubiquitination of axin negatively regulates Wnt/β-catenin signaling | Q37264400 | ||
| Fbw7 dimerization determines the specificity and robustness of substrate degradation. | Q37388879 | ||
| The active form of E6-associated protein (E6AP)/UBE3A ubiquitin ligase is an oligomer | Q37459194 | ||
| Ubiquitination of substrates by esterification | Q37924935 | ||
| The SIAH E3 ubiquitin ligases promote Wnt/β-catenin signaling through mediating Wnt-induced Axin degradation | Q38762765 | ||
| The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated β-catenin by sequestering TCF4 to the nuclear membrane | Q38836796 | ||
| Mdm2 Splice isoforms regulate the p53/Mdm2/Mdm4 regulatory circuit via RING domain-mediated ubiquitination of p53 and Mdm4. | Q38976292 | ||
| CBL linker region and RING finger mutations lead to enhanced granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling via elevated levels of JAK2 and LYN. | Q39148813 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P304 | page(s) | 39 | |
| P577 | publication date | 2020-02-04 | |
| P1433 | published in | Frontiers in Cell and Developmental Biology | Q27725488 |
| P1476 | title | How to Inactivate Human Ubiquitin E3 Ligases by Mutation | |
| P478 | volume | 8 |
| Q99614314 | A Membrane-Tethered Ubiquitination Pathway Regulates Hedgehog Signaling and Heart Development | cites work | P2860 |
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