scholarly article | Q13442814 |
P2093 | author name string | Yanping Zhang | |
Hui Tian | |||
Junnian Zheng | |||
Aiwen Jin | |||
Nicole R Tackmann | |||
P2860 | cites work | PUMA, a novel proapoptotic gene, is induced by p53 | Q24291463 |
RING domain-mediated interaction is a requirement for MDM2's E3 ligase activity | Q40110366 | ||
Inhibition of p53 degradation by Mdm2 acetylation | Q40580015 | ||
DNA damage-induced MDMX degradation is mediated by MDM2. | Q40636352 | ||
Temporal dissection of p53 function in vitro and in vivo | Q44365729 | ||
Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo. | Q44896717 | ||
The MDM2 RING-finger domain is required to promote p53 nuclear export | Q45301160 | ||
20 years studying p53 functions in genetically engineered mice | Q84583331 | ||
Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization | Q24292930 | ||
Acetylation is indispensable for p53 activation | Q24313477 | ||
Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain | Q24314763 | ||
Mdmx enhances p53 ubiquitination by altering the substrate preference of the Mdm2 ubiquitin ligase | Q24316238 | ||
MDMX: a novel p53-binding protein with some functional properties of MDM2 | Q24561971 | ||
The first 30 years of p53: growing ever more complex | Q24645732 | ||
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2 | Q27642888 | ||
p53, the cellular gatekeeper for growth and division | Q27860990 | ||
WAF1, a potential mediator of p53 tumor suppression | Q27861121 | ||
Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53 | Q28214793 | ||
MDMX inhibits the p300/CBP-mediated acetylation of p53 | Q28216910 | ||
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene | Q28306186 | ||
Targeted inactivation of Mdm2 RING finger E3 ubiquitin ligase activity in the mouse reveals mechanistic insights into p53 regulation | Q28508240 | ||
Regulation of p53 by Mdm2 E3 ligase function is dispensable in embryogenesis and development, but essential in response to DNA damage | Q28510160 | ||
Blinded by the Light: The Growing Complexity of p53 | Q29547590 | ||
Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53 | Q29614430 | ||
SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells | Q29615006 | ||
Modes of p53 regulation | Q29615657 | ||
Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53 | Q29615851 | ||
Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53 | Q29617850 | ||
The p53 orchestra: Mdm2 and Mdmx set the tone | Q34020353 | ||
Validation of MdmX as a therapeutic target for reactivating p53 in tumors | Q34209099 | ||
p300/CBP/p53 interaction and regulation of the p53 response | Q34254607 | ||
Mdm2 RING mutation enhances p53 transcriptional activity and p53-p300 interaction | Q34292937 | ||
p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2. | Q34585107 | ||
MdmX protein is essential for Mdm2 protein-mediated p53 polyubiquitination | Q35084991 | ||
The p53 inhibitors MDM2/MDMX complex is required for control of p53 activity in vivo | Q35122947 | ||
Heterodimerization of Mdm2 and Mdm4 is critical for regulating p53 activity during embryogenesis but dispensable for p53 and Mdm2 stability | Q35123240 | ||
MDM2 promotes ubiquitination and degradation of MDMX | Q35161842 | ||
The MDM2 RING domain and central acidic domain play distinct roles in MDM2 protein homodimerization and MDM2-MDMX protein heterodimerization | Q35608179 | ||
The Mdm2 RING domain C-terminus is required for supramolecular assembly and ubiquitin ligase activity | Q35610627 | ||
p53 regulation: teamwork between RING domains of Mdm2 and MdmX. | Q37963700 | ||
p53 promotes VEGF expression and angiogenesis in the absence of an intact p21-Rb pathway. | Q39187173 | ||
MdmX protects p53 from Mdm2-mediated degradation | Q39450800 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 52 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 21614-21622 | |
P577 | publication date | 2017-11-09 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Inactivation of the MDM2 RING domain enhances p53 transcriptional activity in mice | |
P478 | volume | 292 |
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