The architects of bacterial DNA bridges: a structurally and functionally conserved family of proteins

scientific article published on 04 December 2019

The architects of bacterial DNA bridges: a structurally and functionally conserved family of proteins is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1098/RSOB.190223
P932PMC publication ID6936261
P698PubMed publication ID31795918

P50authorRemus T DameQ38305121
P2093author name stringL Qin
A M Erkelens
F Ben Bdira
P2860cites workChromosomal macrodomains and associated proteins: implications for DNA organization and replication in gram negative bacteriaQ21092425
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Regulation of chromatin by histone modificationsQ24635070
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Lsr2 is a nucleoid-associated protein that targets AT-rich sequences and virulence genes in Mycobacterium tuberculosisQ27659569
H-NS forms a superhelical protein scaffold for DNA condensationQ27664196
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Structural basis for recognition of AT-rich DNA by unrelated xenogeneic silencing proteinsQ27670439
Structural Insights into the Regulation of Foreign Genes in Salmonella by the Hha/H-NS ComplexQ27676910
The Structure of the Oligomerization Domain of Lsr2 from Mycobacterium tuberculosis Reveals a Mechanism for Chromosome Organization and ProtectionQ27681284
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Chromosome organization in bacteria: mechanistic insights into genome structure and functionQ91452344
Association of nucleoid proteins with coding and non-coding segments of the Escherichia coli genome.Q38309827
Homeostatic regulation of supercoiling sensitivity coordinates transcription of the bacterial genomeQ38312050
Selective silencing of foreign DNA with low GC content by the H-NS protein in SalmonellaQ38312504
A genetic selection for supercoiling mutants of Escherichia coli reveals proteins implicated in chromosome structureQ38321551
Variable structures of Fis-DNA complexes determined by flanking DNA-protein contactsQ38350596
Genome-wide identification of H-NS-controlled, temperature-regulated genes in Escherichia coli K-12.Q38358978
Structure of histone-based chromatin in Archaea.Q38629808
Chromatin structure and gene expressionQ39220942
H-NS is a part of a thermally controlled mechanism for bacterial gene regulation.Q39497729
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H-NS mediated compaction of DNA visualised by atomic force microscopyQ39584438
The Escherichia coli stpA gene is transiently expressed during growth in rich medium and is induced in minimal medium and by stress conditions.Q39844343
Effects of sigmaS and the transcriptional activator AppY on induction of the Escherichia coli hya and cbdAB-appA operons in response to carbon and phosphate starvationQ39845067
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Lsr2 of Mycobacterium tuberculosis is a DNA-bridging proteinQ28487199
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The Escherichia coli phosphotyrosine proteome relates to core pathways and virulenceQ28533887
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Organization of supercoil domains and their reorganization by transcriptionQ28768389
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The T4 phage DNA mimic protein Arn inhibits the DNA binding activity of the bacterial histone-like protein H-NS.Q30365649
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Differential effects and interactions of endogenous and horizontally acquired H-NS-like proteins in pathogenic Escherichia coliQ33621541
A divalent switch drives H-NS/DNA-binding conformations between stiffening and bridging modes.Q33631136
The Rok protein of Bacillus subtilis represses genes for cell surface and extracellular functionsQ33714630
The transcriptional regulator Rok binds A+T-rich DNA and is involved in repression of a mobile genetic element in Bacillus subtilis.Q33750107
The bacterial DNA-binding protein H-NS represses ribosomal RNA transcription by trapping RNA polymerase in the initiation complexQ33901055
Repression of phase-variable cup gene expression by H-NS-like proteins in Pseudomonas aeruginosaQ33911477
DNA looping-mediated repression by histone-like protein H-NS: specific requirement of Esigma70 as a cofactor for loopingQ34055951
Shigella flexneri 2a strain 2457T expresses three members of the H-NS-like protein family: characterization of the Sfh proteinQ34219679
The evolution of SMC proteins: phylogenetic analysis and structural implicationsQ34281852
High-order oligomerization is required for the function of the H-NS family member MvaT in Pseudomonas aeruginosaQ34297693
Nucleosome arrays reveal the two-start organization of the chromatin fiberQ34371762
High-resolution mapping of the spatial organization of a bacterial chromosomeQ34380184
JPred4: a protein secondary structure prediction serverQ34472202
Condensin-Based Chromosome Organization from Bacteria to VertebratesQ34515902
Developmental biology of Streptomyces from the perspective of 100 actinobacterial genome sequencesQ34629213
Lysine succinylation is a frequently occurring modification in prokaryotes and eukaryotes and extensively overlaps with acetylationQ34954115
Bridged filaments of histone-like nucleoid structuring protein pause RNA polymerase and aid termination in bacteriaQ35111368
The competence transcription factor of Bacillus subtilis recognizes short A/T-rich sequences arranged in a unique, flexible pattern along the DNA helixQ35200591
The pleiotropic response regulator DegU functions as a priming protein in competence development in Bacillus subtilisQ35202131
Oligomerization mechanisms of an H-NS family protein, Pmr, encoded on the plasmid pCAR1 provide a molecular basis for functions of H-NS family membersQ35227911
H-NS in Gram-negative bacteria: a family of multifaceted proteinsQ35579488
Differential protease-mediated turnover of H-NS and StpA revealed by a mutation altering protein stability and stationary-phase survival of Escherichia coliQ35631720
Escherichia coli protein analogs StpA and H-NS: regulatory loops, similar and disparate effects on nucleic acid dynamicsQ35846232
Gene silencing H-NS paralogue StpA forms a rigid protein filament along DNA that blocks DNA accessibilityQ35906107
Plasmids bearing hfq and the hns-like gene stpA complement hns mutants in modulating arginine decarboxylase gene expression in Escherichia coliQ35980094
Nucleoprotein filament formation is the structural basis for bacterial protein H-NS gene silencingQ36093140
Nucleosome and chromatin fiber dynamicsQ36101104
Environmental signals controlling expression of virulence determinants in bacteriaQ36109256
Gene 5.5 protein of bacteriophage T7 inhibits the nucleoid protein H-NS of Escherichia coliQ36129355
The MaoP/maoS Site-Specific System Organizes the Ori Region of the E. coli Chromosome into a Macrodomain.Q36132532
H-NS Regulates Gene Expression and Compacts the Nucleoid: Insights from Single-Molecule ExperimentsQ36146713
Long range chromosome organization in Escherichia coli: The position of the replication origin defines the non-structured regions and the Right and Left macrodomainsQ36366966
MvaT Family Proteins Encoded on IncP-7 Plasmid pCAR1 and the Host Chromosome Regulate the Host Transcriptome Cooperatively but DifferentlyQ36497535
Alba shapes the archaeal genome using a delicate balance of bridging and stiffening the DNA.Q36503563
Acetylome analysis reveals the involvement of lysine acetylation in biosynthesis of antibiotics in Bacillus amyloliquefaciensQ36517087
The novel Hha/YmoA family of nucleoid-associated proteins: use of structural mimicry to modulate the activity of the H-NS family of proteinsQ36658260
Topological domain structure of the Escherichia coli chromosomeQ36661286
Comparative genomics of mycobacterial proteasesQ36870333
Mechanism of DNA organization by Mycobacterium tuberculosis protein Lsr2.Q36878497
Tracking bacterial virulence: global modulators as indicators.Q36893565
The quantitative and condition-dependent Escherichia coli proteomeQ36956238
H-NS family members function coordinately in an opportunistic pathogenQ36999879
Antirepression as a second mechanism of transcriptional activation by a minor groove binding proteinQ37318351
Macrodomain organization of the Escherichia coli chromosome.Q37592872
Bacterial nucleoid-associated proteins, nucleoid structure and gene expressionQ37688895
Structure and dynamics of the crenarchaeal nucleoid.Q38077247
The 5.5 protein of phage T7 inhibits H-NS through interactions with the central oligomerization domainQ38285825
Large-scale monitoring of pleiotropic regulation of gene expression by the prokaryotic nucleoid-associated protein, H-NS.Q38302084
Nucleotide sequence of a newly-identified Escherichia coli gene, stpA, encoding an H-NS-like protein.Q40536273
The DNA-mimic antirestriction proteins ArdA ColIB-P9, Arn T4, and Ocr T7 as activators of H-NS-dependent gene transcription.Q40567432
The Escherichia coli nucleoid protein H-NS functions directly as a transcriptional repressor.Q40872265
Antibacterial phage ORFans of Pseudomonas aeruginosa phage LUZ24 reveal a novel MvaT inhibiting protein.Q40900099
Coordinated and differential expression of histone-like proteins in Escherichia coli: regulation and function of the H-NS analog StpA.Q41077231
Microarray analysis of temperature-induced transcriptome of Yersinia pestisQ41460599
The positive regulator CfaD overcomes the repression mediated by histone-like protein H-NS (H1) in the CFA/I fimbrial operon of Escherichia coliQ41529169
Growth phase-dependent expression profiles of three vital H-NS family proteins encoded on the chromosome of Pseudomonas putida KT2440 and on the pCAR1 plasmidQ41558018
Interaction between the bacterial nucleoid associated proteins Hha and H-NS involves a conformational change of HhaQ41824879
DNA bridging: a property shared among H-NS-like proteinsQ41844405
Dynamic distribution of seqa protein across the chromosome of escherichia coli K-12.Q41979738
Replication cycle-coordinated change of the adenine nucleotide-bound forms of DnaA protein in Escherichia coliQ42085318
Functions of the Hha and YdgT proteins in transcriptional silencing by the nucleoid proteins, H-NS and StpA, in Escherichia coliQ42168572
Mechanism of environmentally driven conformational changes that modulate H-NS DNA-bridging activityQ42380111
Structural basis for H-NS-mediated trapping of RNA polymerase in the open initiation complex at the rrnB P1.Q42664136
Temperature-dependent conjugative transfer of R27: role of chromosome- and plasmid-encoded Hha and H-NS proteinsQ42863256
Obligate heterodimerization of the archaeal Alba2 protein with Alba1 provides a mechanism for control of DNA packagingQ43017813
Ser/Thr/Tyr phosphoproteome analysis of pathogenic and non-pathogenic Pseudomonas speciesQ43491036
A truncated H-NS-like protein from enteropathogenic Escherichia coli acts as an H-NS antagonistQ45231403
Condensin- and Replication-Mediated Bacterial Chromosome Folding and Origin Condensation Revealed by Hi-C and Super-resolution Imaging.Q46681388
Charged residues in the H-NS linker drive DNA binding and gene silencing in single cells.Q47433869
Investigation of the self-association and hetero-association interactions of H-NS and StpA from EnterobacteriaQ50054725
H-NS promotes looped domain formation in the bacterial chromosomeQ50067068
An H-NS-like stealth protein aids horizontal DNA transmission in bacteriaQ50074297
Genetic and biochemical interactions between the bacterial replication initiator DnaA and the nucleoid-associated protein Rok in Bacillus subtilis.Q50350067
Multiscale Structuring of the E. coli Chromosome by Nucleoid-Associated and Condensin Proteins.Q52390782
Repression by binding of H-NS within the transcription unit.Q52579807
Evolution of Bacterial Global Modulators: Role of a Novel H-NS Paralogue in the Enteroaggregative Escherichia coli Strain 042.Q52632413
The MatP/matS site-specific system organizes the terminus region of the E. coli chromosome into a macrodomain.Q53441904
On the structure of the folded chromosome of Escherichia coliQ54101766
Systematic mutational analysis revealing the functional domain organization of Escherichia coli nucleoid protein H-NS.Q54578667
StpA and Hha stimulate pausing by RNA polymerase by promoting DNA-DNA bridging of H-NS filaments.Q55356316
Quantitative Determination of DNA Bridging Efficiency of Chromatin ProteinsQ56888855
Post-translational modification of nucleoid-associated proteins: an extra layer of functional modulation in bacteria?Q57033829
Two Faces of CwlM, an Essential PknB Substrate, in Mycobacterium tuberculosisQ57044784
MvaT proteins in Pseudomonas spp.: a novel class of H-NS-like proteinsQ57176930
On the Origin of the Selectivity of Plasmidic H-NS towards Horizontally Acquired DNA: Linking H-NS Oligomerization and Cooperative DNA BindingQ57962489
New Roles for Key Residues in Helices H1 and H2 of the Escherichia coli H-NS N-terminal Domain: H-NS Dimer Stabilization and Hha BindingQ57962553
Structure and function of archaeal histonesQ58286649
The Major Architects of Chromatin: Architectural Proteins in Bacteria, Archaea and EukaryotesQ58286818
How bacterial xenogeneic silencer rok distinguishes foreign from self DNA in its resident genomeQ58696868
A single molecule analysis of H-NS uncouples DNA binding affinity from DNA specificityQ58728313
Transcriptional silencing and thermoregulation of gene expression in Escherichia coliQ59097717
Protein lysine acetylation plays a regulatory role in Bacillus subtilis multicellularityQ59126458
Chromatin Fiber Folding: Requirement for the Histone H4 N-terminal TailQ61041700
H-NS uses an autoinhibitory conformational switch for environment-controlled gene silencingQ61821275
H-NS cooperative binding to high-affinity sites in a regulatory element results in transcriptional silencingQ63430392
Gene duplications in the E. coli genome: common themes among pathotypesQ64091842
Silencing cryptic specialized metabolism in Streptomyces by the nucleoid-associated protein Lsr2.Q64946672
Differences in the binding of H1 variants to DNA. Cooperativity and linker-length related distributionQ67989761
Twelve species of the nucleoid-associated protein from Escherichia coli. Sequence recognition specificity and DNA binding affinityQ73157405
Three-way interactions among the Sfh, StpA and H-NS nucleoid-structuring proteins of Shigella flexneri 2a strain 2457TQ73481709
Expression of the hemolysin operon in Escherichia coli is modulated by a nucleoid-protein complex that includes the proteins Hha and H-NSQ73706944
Oligomerization and DNA-binding capacity of Pmr, a histone-like protein H1 (H-NS) family protein encoded on IncP-7 carbazole-degradative plasmid pCAR1Q83930337
P433issue12
P304page(s)190223
P577publication date2019-12-04
P1433published inOpen BiologyQ7095958
P1476titleThe architects of bacterial DNA bridges: a structurally and functionally conserved family of proteins
P478volume9

Reverse relations

cites work (P2860)
Q94464346Chromosome Segregation Proteins as Coordinators of Cell Cycle in Response to Environmental Conditions
Q100946076Overexpression of the third H-NS paralogue H-NS2 compensates fitness loss in hns mutants of the enteroaggregative Escherichia coli strain 042
Q92565084Structural basis for osmotic regulation of the DNA binding properties of H-NS proteins

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