Influence of Liver Fibrosis on Lobular Zonation

scientific article published on 02 December 2019

Influence of Liver Fibrosis on Lobular Zonation is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3390/CELLS8121556
P932PMC publication ID6953125
P698PubMed publication ID31810365

P50authorYasser A AhmedQ60329586
Christian H HollandQ89684581
Rolf GebhardtQ99628521
Julio Saez-RodriguezQ41044850
Ahmed GhallabQ43208341
P2093author name stringChristian Trautwein
Jan G Hengstler
Dirk Drasdo
Maximilian Hatting
Marie-Luise Berres
Reham Hassan
Jörg Reinders
Walaa Murad
Madlen Matz-Soja
Kai Markus Schneider
Maiju Myllys
Ayham Zaza
Eman A Abdelrahim
Tahany Abbas
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Modern pathogenetic concepts of liver fibrosis suggest stellate cells and TGF-beta as major players and therapeutic targetsQ28303698
limma powers differential expression analyses for RNA-sequencing and microarray studiesQ29617988
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Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regenerationQ30495068
Optimality in the zonation of ammonia detoxification in rodent liver.Q51697079
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Bile micro-infarcts in cholestasis are initiated by rupture of the apical hepatocyte membrane and cause shunting of bile to sinusoidal bloodQ57111980
Burden of liver disease in Europe: Epidemiology and analysis of risk factors to identify prevention policiesQ57164796
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Iroquois Homeodomain transcription factors in ventricular conduction system and arrhythmia.Q64938031
Liver Zonation in Health and Disease: Hypoxia and Hypoxia-Inducible Transcription Factors as Concert Masters.Q64968927
The enterohepatic circulation of urea nitrogenQ71269450
Differential gene expression in periportal and perivenous mouse hepatocytesQ79282635
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Spatio-temporal visualization of the distribution of acetaminophen as well as its metabolites and adducts in mouse livers by MALDI MSIQ90433800
The pyrrolizidine alkaloid senecionine induces CYP-dependent destruction of sinusoidal endothelial cells and cholestasis in miceQ90673668
Hepatic heparan sulfate is a master regulator of hepcidin expression and iron homeostasis in human hepatocytes and miceQ91966980
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Benchmark and integration of resources for the estimation of human transcription factor activitiesQ92152603
A step-by-step workflow for low-level analysis of single-cell RNA-seq data with Bioconductor.Q31146507
Functional contribution of elevated circulating and hepatic non-classical CD14CD16 monocytes to inflammation and human liver fibrosisQ33604746
Aberrant expression and distribution of enzymes of the urea cycle and other ammonia metabolizing pathways in dogs with congenital portosystemic shuntsQ33778949
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Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.Q37121662
Functional characterization of somatic mutations in cancer using network-based inference of protein activityQ37292348
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Update on hepatic stellate cells: pathogenic role in liver fibrosis and novel isolation techniquesQ37965682
The ascending pathophysiology of cholestatic liver disease.Q39040911
Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissueQ39658669
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Physiologically-based modelling in mice suggests an aggravated loss of clearance capacity after toxic liver damageQ41109384
Cholestasis-induced adaptive remodeling of interlobular bile ductsQ41477905
Adverse outcome pathways: opportunities, limitations and open questionsQ42307037
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Integrated metabolic spatial-temporal model for the prediction of ammonia detoxification during liver damage and regenerationQ46550945
A frequent misinterpretation in current research on liver fibrosis: the vessel in the center of CCl4-induced pseudolobules is a portal veinQ46907265
Perturbation-response genes reveal signaling footprints in cancer gene expressionQ48319034
Effect of reducing brain glutamine synthesis on metabolic symptoms of hepatic encephalopathyQ48324424
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
limmaQ112236343
edgeRQ113334690
P433issue12
P577publication date2019-12-02
P1433published inCellsQ27724621
P1476titleInfluence of Liver Fibrosis on Lobular Zonation
P478volume8

Reverse relations

cites work (P2860)
Q102059001Comparing distress of mouse models for liver damage
Q90478256Concomitant inflammation/metabolism transcriptional regulatory networks in liver disease
Q92644459Liver fibrosis causes periportalization of lobular zonation
Q91634646PPARG as therapeutic target for antifibrotic therapy
Q99634252The Genetic Architecture of Carbon Tetrachloride-Induced Liver Fibrosis in Mice

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