review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Fabrizio Ensoli | Q55069671 |
Valentina Bordignon | Q56450971 | ||
Luigi Toma | Q62664887 | ||
Enea Gino Di Domenico | Q42838379 | ||
P2093 | author name string | Elisabetta Trento | |
Giovanna D'Agosto | |||
Paola Cordiali-Fei | |||
P2860 | cites work | The cancer burden attributable to biologic agents | Q38293923 |
Kaposi's sarcoma-associated herpesvirus latent and lytic gene expression as revealed by DNA arrays | Q38305362 | ||
Kaposi's sarcoma-associated herpesvirus induces the ATM and H2AX DNA damage response early during de novo infection of primary endothelial cells, which play roles in latency establishment | Q38329562 | ||
Therapeutic opportunities within the DNA damage response | Q38364665 | ||
Identification of Kaposi Sarcoma Herpesvirus (KSHV) vIRF1 Protein as a Novel Interaction Partner of Human Deubiquitinase USP7. | Q38801652 | ||
The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway | Q22065419 | ||
Nucleophosmin acts as a novel AP2alpha-binding transcriptional corepressor during cell differentiation | Q24298255 | ||
The CHK2-BRCA1 tumour suppressor pathway ensures chromosomal stability in human somatic cells | Q24305557 | ||
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage | Q24306743 | ||
Kaposi's sarcoma-associated herpesvirus ORF57 protein interacts with PYM to enhance translation of viral intronless mRNAs | Q24309306 | ||
Recruitment of the complete hTREX complex is required for Kaposi's sarcoma-associated herpesvirus intronless mRNA nuclear export and virus replication | Q24310689 | ||
Autophagy mediates the mitotic senescence transition | Q24320401 | ||
Human herpesvirus 8 LANA interacts with proteins of the mSin3 corepressor complex and negatively regulates Epstein-Barr virus gene expression in dually infected PEL cells | Q24527215 | ||
Protein interactions targeting the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus to cell chromosomes | Q24538878 | ||
Kaposi's sarcoma-associated herpesvirus-encoded latency-associated nuclear antigen modulates K1 expression through its cis-acting elements within the terminal repeats | Q24543014 | ||
Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells | Q24555724 | ||
Structural basis of inhibition of CDK-cyclin complexes by INK4 inhibitors | Q24597269 | ||
Megabase chromatin domains involved in DNA double-strand breaks in vivo | Q24680284 | ||
Co-infections and Pathogenesis of KSHV-Associated Malignancies | Q26766493 | ||
Modulation of DNA damage and repair pathways by human tumour viruses | Q26825783 | ||
The crystal structure of the DNA-binding domain of vIRF-1 from the oncogenic KSHV reveals a conserved fold for DNA binding and reinforces its role as a transcription factor | Q27676606 | ||
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes | Q27860662 | ||
The DNA Damage Response: Making It Safe to Play with Knives | Q27861055 | ||
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139 | Q28131715 | ||
A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM | Q28270543 | ||
DNA damage and the balance between survival and death in cancer biology | Q28271163 | ||
H2AX: the histone guardian of the genome | Q28274279 | ||
The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer | Q28297155 | ||
ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage | Q28364113 | ||
KSHV reactivation from latency requires Pim-1 and Pim-3 kinases to inactivate the latency-associated nuclear antigen LANA | Q28474913 | ||
Kaposi sarcoma herpes virus latency associated nuclear antigen protein release the G2/M cell cycle blocks by modulating ATM/ATR mediated checkpoint pathway | Q28540116 | ||
Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage | Q29614218 | ||
GammaH2AX and cancer | Q29614974 | ||
DNA repair pathways as targets for cancer therapy | Q29615572 | ||
Identification of microRNAs of the herpesvirus family | Q29618671 | ||
Global burden of cancers attributable to infections in 2008: a review and synthetic analysis | Q29620303 | ||
Kaposi's sarcoma-associated herpesvirus-encoded LANA can interact with the nuclear mitotic apparatus protein to regulate genome maintenance and segregation | Q30482603 | ||
The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks | Q33286997 | ||
Viral oncogene-induced DNA damage response is activated in Kaposi sarcoma tumorigenesis | Q33301012 | ||
Nucleophosmin phosphorylation by v-cyclin-CDK6 controls KSHV latency | Q33545232 | ||
Kinetics of Kaposi's sarcoma-associated herpesvirus gene expression | Q33653424 | ||
Glycyrrhizic acid alters Kaposi sarcoma-associated herpesvirus latency, triggering p53-mediated apoptosis in transformed B lymphocytes. | Q33683742 | ||
Kaposi's sarcoma-associated herpesvirus reactivation is regulated by interaction of latency-associated nuclear antigen with recombination signal sequence-binding protein Jkappa, the major downstream effector of the Notch signaling pathway | Q33737793 | ||
A cluster of latently expressed genes in Kaposi's sarcoma-associated herpesvirus | Q33784966 | ||
A complex translational program generates multiple novel proteins from the latently expressed kaposin (K12) locus of Kaposi's sarcoma-associated herpesvirus. | Q33815534 | ||
Latent nuclear antigen of Kaposi's sarcoma-associated herpesvirus interacts with RING3, a homolog of the Drosophila female sterile homeotic (fsh) gene | Q33824419 | ||
CREB-binding protein and histone deacetylase regulate the transcriptional activity of Kaposi's sarcoma-associated herpesvirus open reading frame 50 | Q33854980 | ||
Efficient persistence of extrachromosomal KSHV DNA mediated by latency-associated nuclear antigen | Q33859518 | ||
Cloning and identification of a microRNA cluster within the latency-associated region of Kaposi's sarcoma-associated herpesvirus | Q33883910 | ||
p53 inhibition by the LANA protein of KSHV protects against cell death | Q33885642 | ||
Viral cyclins | Q33920746 | ||
Regulation of homologous recombination in eukaryotes | Q33966065 | ||
Inhibition of p300 histone acetyltransferase by viral interferon regulatory factor | Q33966269 | ||
Kaposi's sarcoma-associated herpesvirus: a new DNA tumor virus | Q34132022 | ||
Update on KSHV epidemiology, Kaposi Sarcoma pathogenesis, and treatment of Kaposi Sarcoma | Q34168712 | ||
Multifunctional role of ATM/Tel1 kinase in genome stability: from the DNA damage response to telomere maintenance | Q34176919 | ||
Mechanism of action of antitumor drugs that interact with microtubules and tubulin | Q34188643 | ||
The DNA damage response in viral-induced cellular transformation | Q34246710 | ||
Kaposi's Sarcoma-Associated Herpesvirus microRNAs | Q34273195 | ||
The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus supports latent DNA replication in dividing cells | Q34355092 | ||
Selenomethionine regulation of p53 by a ref1-dependent redox mechanism | Q34394902 | ||
Inhibition of the ATM/p53 signal transduction pathway by Kaposi's sarcoma-associated herpesvirus interferon regulatory factor 1. | Q34434681 | ||
The latent nuclear antigen of Kaposi sarcoma-associated herpesvirus targets the retinoblastoma-E2F pathway and with the oncogene Hras transforms primary rat cells | Q34511161 | ||
Virus-encoded microRNAs: an overview and a look to the future | Q34544400 | ||
Molecular and cellular mechanisms of KSHV oncogenesis of Kaposi's sarcoma associated with HIV/AIDS | Q34663095 | ||
KSHV LANA--the master regulator of KSHV latency | Q34774797 | ||
Lytic infection of Kaposi's sarcoma-associated herpesvirus induces DNA double-strand breaks and impairs non-homologous end joining. | Q50990735 | ||
Targeting mitotic chromosomes: a conserved mechanism to ensure viral genome persistence. | Q51831648 | ||
Familial Kaposi's Sarcoma in HHV8 infected subjects presenting the G-174C allele of the IL-6 promoter: a possible role for EBV? | Q51846023 | ||
Transient activation of p53 in G2 phase is sufficient to induce senescence. | Q53043642 | ||
The Transcriptional Activity of cAMP Response Element-binding Protein-binding Protein Is Modulated by the Latency Associated Nuclear Antigen of Kaposi's Sarcoma-associated Herpesvirus | Q57662902 | ||
Associations of Classic Kaposi Sarcoma with Common Variants in Genes that Modulate Host Immunity | Q57665241 | ||
Three-Dimensional Structure of the Human DNA-PKcs/Ku70/Ku80 Complex Assembled on DNA and Its Implications for DNA DSB Repair | Q58660114 | ||
Transcription profile of Kaposi's sarcoma-associated herpesvirus in primary Kaposi's sarcoma lesions as determined by real-time PCR arrays | Q73344152 | ||
Electrochemotherapy-induced virus disappearance in HHV-8-positive skin nodules of Kaposi sarcoma: first histological and immunohistochemical demonstration of efficacy | Q84584664 | ||
A seroprevalence study of human herpesvirus type 8 (HHV8) in eastern and Central Africa and in the Mediterranean area. | Q38884285 | ||
Prevalence and risk factors for human herpesvirus 8 infection in northern Cameroon | Q39395409 | ||
Characterization of human herpesvirus 8 ORF59 protein (PF-8) and mapping of the processivity and viral DNA polymerase-interacting domains | Q39597623 | ||
Differential regulation of the overlapping Kaposi's sarcoma-associated herpesvirus vGCR (orf74) and LANA (orf73) promoters | Q39602154 | ||
Octamer-binding sequence is a key element for the autoregulation of Kaposi's sarcoma-associated herpesvirus ORF50/Lyta gene expression | Q39603733 | ||
Transcripts encoding K12, v-FLIP, v-cyclin, and the microRNA cluster of Kaposi's sarcoma-associated herpesvirus originate from a common promoter. | Q39612221 | ||
Bub1 and CENP-F can contribute to Kaposi's sarcoma-associated herpesvirus genome persistence by targeting LANA to kinetochores | Q39675686 | ||
DNA-PK/Ku complex binds to latency-associated nuclear antigen and negatively regulates Kaposi's sarcoma-associated herpesvirus latent replication. | Q39725564 | ||
Kaposi's sarcoma-associated herpesvirus gene expression in endothelial (spindle) tumor cells | Q39877852 | ||
Kaposi's sarcoma-associated herpesvirus encodes a functional cyclin. | Q39878517 | ||
The cyclin encoded by Kaposi's sarcoma-associated herpesvirus stimulates cdk6 to phosphorylate the retinoblastoma protein and histone H1. | Q39879780 | ||
Latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus up-regulates transcription of human telomerase reverse transcriptase promoter through interaction with transcription factor Sp1. | Q39992257 | ||
Disruption of Kaposi's sarcoma-associated herpesvirus latent nuclear antigen leads to abortive episome persistence | Q40163096 | ||
Ets-1-dependent expression of vascular endothelial growth factor receptors is activated by latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus through interaction with Daxx | Q40252446 | ||
The nucleosomal surface as a docking station for Kaposi's sarcoma herpesvirus LANA. | Q40318272 | ||
Kaposi's sarcoma-associated herpesvirus-encoded latency-associated nuclear antigen induces chromosomal instability through inhibition of p53 function | Q40335991 | ||
Constitutively active K-cyclin/cdk6 kinase in Kaposi sarcoma-associated herpesvirus-infected cells | Q40426996 | ||
The kaposin B protein of KSHV activates the p38/MK2 pathway and stabilizes cytokine mRNAs. | Q40461940 | ||
Interferon-Induced Antiviral Actions and Their Regulation | Q40484830 | ||
The Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen binds to specific sequences at the left end of the viral genome through its carboxy-terminus | Q40746913 | ||
Lytic growth of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in culture | Q41225141 | ||
Our cells get stressed too! Implications for human disease | Q41693676 | ||
Kaposi's sarcoma-associated herpesvirus LANA protein downregulates nuclear glycogen synthase kinase 3 activity and consequently blocks differentiation | Q41846091 | ||
Regulation of the interaction between glycogen synthase kinase 3 and the Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen | Q41849965 | ||
The latency-associated nuclear antigen interacts with MeCP2 and nucleosomes through separate domains | Q41860564 | ||
Kaposi's sarcoma-associated herpesvirus latent protein LANA interacts with HIF-1 alpha to upregulate RTA expression during hypoxia: Latency control under low oxygen conditions | Q42049779 | ||
Ser18 and 23 phosphorylation is required for p53-dependent apoptosis and tumor suppression | Q42062886 | ||
ATM is a target for positive regulation by E2F-1. | Q42806424 | ||
FLIP-mediated autophagy regulation in cell death control | Q42832950 | ||
A mitotic role for the DNA damage-responsive CHK2 kinase | Q44178226 | ||
MDM2 and CDKN1A gene polymorphisms and risk of Kaposi's sarcoma in African and Caucasian patients | Q44248155 | ||
Recruitment of the tumour suppressor protein p73 by Kaposi's Sarcoma Herpesvirus latent nuclear antigen contributes to the survival of primary effusion lymphoma cells | Q44703163 | ||
Antibodies to human herpesvirus type 8 in the general population and in Kaposi's sarcoma patients. | Q45878585 | ||
The oncogenic potential of Kaposi's sarcoma-associated herpesvirus cyclin is exposed by p53 loss in vitro and in vivo | Q46725222 | ||
Subversion of autophagy by Kaposi's sarcoma-associated herpesvirus impairs oncogene-induced senescence | Q46798265 | ||
Effective treatment of Kaposi's sarcoma by electrochemotherapy and intravenous bleomycin administration | Q47443263 | ||
Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen Induces Expression of the Helix-Loop-Helix Protein Id-1 in Human Endothelial Cells | Q34976840 | ||
Molecular biology of KSHV lytic reactivation | Q35014918 | ||
Stimulus-dependent dynamics of p53 in single cells | Q35088876 | ||
The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus manipulates the activity of glycogen synthase kinase-3beta | Q35104781 | ||
Molecular Biology of Kaposi's Sarcoma-associated Herpesvirus and Related Oncogenesis | Q35124404 | ||
Distribution of human herpesvirus-8 latently infected cells in Kaposi's sarcoma, multicentric Castleman's disease, and primary effusion lymphoma | Q35131811 | ||
A novel mechanism inducing genome instability in Kaposi's sarcoma-associated herpesvirus infected cells | Q35161728 | ||
Reactivation of the p53 pathway as a treatment modality for KSHV-induced lymphomas. | Q35664106 | ||
The cell cycle and how it is steered by Kaposi's sarcoma-associated herpesvirus cyclin. | Q35786023 | ||
Interactions of viruses with the cellular DNA repair machinery | Q35848546 | ||
Treatment of Kaposi sarcoma-associated herpesvirus-associated cancers | Q35895560 | ||
Oncogenic Herpesvirus Utilizes Stress-Induced Cell Cycle Checkpoints for Efficient Lytic Replication | Q35927487 | ||
The viral interferon regulatory factors of KSHV: immunosuppressors or oncogenes? | Q35927496 | ||
Nutlin-3 induces apoptosis, disrupts viral latency and inhibits expression of angiopoietin-2 in Kaposi sarcoma tumor cells. | Q35954902 | ||
Regulation of growth signalling and cell cycle by Kaposi's sarcoma-associated herpesvirus genes. | Q35964857 | ||
Global chromatin compaction limits the strength of the DNA damage response | Q36119310 | ||
TREX, SR proteins and export of mRNA. | Q36131499 | ||
HIV and human herpesvirus 8 co-infection across the globe: Systematic review and meta-analysis | Q36167185 | ||
KSHV vFLIP is essential for the survival of infected lymphoma cells | Q36399405 | ||
Kaposi's sarcoma and its associated herpesvirus | Q36487309 | ||
Cell signaling pathways engaged by KSHV. | Q36531004 | ||
H2AX phosphorylation is important for LANA-mediated Kaposi's sarcoma-associated herpesvirus episome persistence | Q36760020 | ||
Lytic cycle switches of oncogenic human gammaherpesviruses | Q36786043 | ||
KSHV infection and the pathogenesis of Kaposi's sarcoma | Q37014777 | ||
Taking the time to make important decisions: the checkpoint effector kinases Chk1 and Chk2 and the DNA damage response | Q37497709 | ||
Restricted expression of Kaposi sarcoma-associated herpesvirus (human herpesvirus 8) genes in Kaposi sarcoma | Q37535731 | ||
mRNA export and cancer | Q37907202 | ||
Pegylated liposomal doxorubicin: a review of its use in metastatic breast cancer, ovarian cancer, multiple myeloma and AIDS-related Kaposi's sarcoma | Q37964713 | ||
New clues to understand the role of THO and other functionally related factors in mRNP biogenesis | Q37972238 | ||
Cellular origin of Kaposi's sarcoma and Kaposi's sarcoma-associated herpesvirus-induced cell reprogramming | Q38107726 | ||
Kaposi's sarcoma-associated herpesvirus ORF57 protein: exploiting all stages of viral mRNA processing. | Q38125077 | ||
The role of Kaposi sarcoma-associated herpesvirus in the pathogenesis of Kaposi sarcoma | Q38248404 | ||
P275 | copyright license | Creative Commons Attribution | Q6905323 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 6 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | virus | Q808 |
catalysis | Q82264 | ||
DNA damage | Q5205747 | ||
organic chemistry | Q11351 | ||
Herpesviridae infectious disease | Q18975237 | ||
P304 | page(s) | 854 | |
P577 | publication date | 2016-06-01 | |
P1433 | published in | International Journal of Molecular Sciences | Q3153277 |
P1476 | title | Activation of DNA Damage Response Induced by the Kaposi's Sarcoma-Associated Herpes Virus | |
P478 | volume | 17 |
Q42323202 | DNA Damage and Repair in Degenerative Diseases 2016 |
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Q38716372 | The DNA damage response promotes polyomavirus JC infection by nucleus to cytoplasm NF- kappaB activation. |
Q59357194 | Virus DNA Replication and the Host DNA Damage Response |
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