Structural and Functional Insights into Small, Glutamine-Rich, Tetratricopeptide Repeat Protein Alpha

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Structural and Functional Insights into Small, Glutamine-Rich, Tetratricopeptide Repeat Protein Alpha is …
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scholarly articleQ13442814

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P356DOI10.3389/FMOLB.2015.00071
P3181OpenCitations bibliographic resource ID2148126
P932PMC publication ID4683186
P698PubMed publication ID26734616
P5875ResearchGate publication ID289524116

P50authorSantiago Martínez-LumbrerasQ57036749
Arjun ThapaliyaQ86035538
Rivka L IsaacsonQ42700334
P2093author name stringEwelina M Krysztofinska
Joanna D Roberts
P2860cites workA ribosome-associating factor chaperones tail-anchored membrane proteinsQ24293683
Chaperoned ubiquitylation--crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complexQ24296990
Cytosolic quality control of mislocalized proteins requires RNF126 recruitment to Bag6Q24300029
SGTA recognizes a noncanonical ubiquitin-like domain in the Bag6-Ubl4A-Trc35 complex to promote endoplasmic reticulum-associated degradationQ24306367
Identification of a novel cellular TPR-containing protein, SGT, that interacts with the nonstructural protein NS1 of parvovirus H-1.Q24523131
Functional interaction of human immunodeficiency virus type 1 Vpu and Gag with a novel member of the tetratricopeptide repeat protein family.Q24523647
Small glutamine-rich tetratricopeptide repeat-containing protein (SGT) interacts with the ubiquitin-dependent endocytosis (UbE) motif of the growth hormone receptorQ24530121
The structure of the tetratricopeptide repeats of protein phosphatase 5: implications for TPR-mediated protein-protein interactionsQ24533152
Structure of TPR domain-peptide complexes: critical elements in the assembly of the Hsp70-Hsp90 multichaperone machineQ27622332
Structural and functional characterization of human SGT and its interaction with Vpu of the human immunodeficiency virus type 1Q27651876
A Structural Model of the Sgt2 Protein and Its Interactions with Chaperones and the Get4/Get5 ComplexQ27671664
Structures of the Sgt2/SGTA Dimerization Domain with the Get5/UBL4A UBL Domain Reveal an Interaction that Forms a Conserved Dynamic InterfaceQ27675050
Structure of the Sgt2/Get5 complex provides insights into GET-mediated targeting of tail-anchored membrane proteinsQ27675806
A Chaperone Cascade Sorts Proteins for Posttranslational Membrane Insertion into the Endoplasmic ReticulumQ27931629
Specific interaction of the 70-kDa heat shock cognate protein with the tetratricopeptide repeatsQ28138187
1H, 13C and 15N assignments of Sgt2 N-terminal dimerisation domain and its binding partner, Get5 Ubiquitin-like domainQ63427580
Snap helix with knob and hole: essential repeats in S. pombe nuclear protein nuc2+Q68697897
The tetratricopeptide repeat: a structural motif mediating protein-protein interactionsQ28145758
hSGT interacts with the N-terminal region of myostatinQ28185056
Association of Vpu-binding protein with microtubules and Vpu-dependent redistribution of HIV-1 Gag proteinQ28205173
Isolation and characterization of human SGT and identification of homologues in Saccharomyces cerevisiae and Caenorhabditis elegansQ28282753
Identification of a targeting factor for posttranslational membrane protein insertion into the ERQ28294726
A brain-specific isoform of small glutamine-rich tetratricopeptide repeat-containing protein binds to Hsc70 and the cysteine string proteinQ28504634
BAG-6 is essential for selective elimination of defective proteasomal substratesQ28505838
Solution structure of the SGTA dimerisation domain and investigation of its interactions with the ubiquitin-like domains of BAG6 and UBL4AQ28545114
Small glutamine-rich tetratricopeptide repeat-containing protein is composed of three structural units with distinct functionsQ28572700
SGTA antagonizes BAG6-mediated protein triageQ28596609
TPR proteins: the versatile helixQ29547585
Posttranslational quality control: folding, refolding, and degrading proteins.Q30323825
A repeating amino acid motif in CDC23 defines a family of proteins and a new relationship among genes required for mitosis and RNA synthesisQ30667531
The cochaperone SGTA (small glutamine-rich tetratricopeptide repeat-containing protein alpha) demonstrates regulatory specificity for the androgen, glucocorticoid, and progesterone receptorsQ34075879
A trimeric protein complex functions as a synaptic chaperone machine.Q34093245
The association of BAG6 with SGTA and tail-anchored proteinsQ34637885
Protein targeting and degradation are coupled for elimination of mislocalized proteinsQ35147351
Regulated protein turnover: snapshots of the proteasome in actionQ35257872
Structures of Get3, Get4, and Get5 provide new models for TA membrane protein targetingQ36570230
Tail-anchored membrane protein insertion into the endoplasmic reticulumQ37140792
Small glutamine-rich tetratricopeptide repeat-containing protein alpha (SGTA), a candidate gene for polycystic ovary syndromeQ37399343
Post-translational translocation into the endoplasmic reticulumQ38069735
BAG6/BAT3: emerging roles in quality control for nascent polypeptidesQ38070391
SGTA: a new player in the molecular co-chaperone gameQ38118665
A cytosolic chaperone complexes with dynamic membrane J-proteins and mobilizes a nonenveloped virus out of the endoplasmic reticulum.Q38542913
A biochemical analysis of the constraints of tail-anchored protein biogenesis.Q38780873
Expression and prognostic role of SGTA in human breast carcinoma correlates with tumor cell proliferationQ39159398
The Rec protein of HERV-K(HML-2) upregulates androgen receptor activity by binding to the human small glutamine-rich tetratricopeptide repeat protein (hSGT).Q39325220
Bat3 promotes the membrane integration of tail-anchored proteinsQ41113412
BAG6 regulates the quality control of a polytopic ERAD substrateQ41482461
SGTA regulates the cytosolic quality control of hydrophobic substratesQ42186480
Control of androgen receptor signaling in prostate cancer by the cochaperone small glutamine rich tetratricopeptide repeat containing protein alphaQ42520361
Binding of SGTA to Rpn13 selectively modulates protein quality controlQ43240834
Severe acute respiratory syndrome coronavirus protein 7a interacts with hSGT.Q48094280
Unique proteasome subunit Xrpn10c is a specific receptor for the antiapoptotic ubiquitin-like protein ScytheQ48109396
Cloning, purification and characterization of the Caenorhabditis elegans small glutamine-rich tetratricopeptide repeat-containing proteinQ57003535
P407language of work or nameEnglishQ1860
P304page(s)71
P577publication date2015-01-01
P1433published inFrontiers in molecular biosciencesQ27726420
P1476titleStructural and Functional Insights into Small, Glutamine-Rich, Tetratricopeptide Repeat Protein Alpha
P478volume2

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cites work (P2860)
Q27468807How Polyomaviruses Exploit the ERAD Machinery to Cause Infection
Q46465153Mechanisms of Tail-Anchored Membrane Protein Targeting and Insertion.
Q42371745SGTA interacts with the proteasomal ubiquitin receptor Rpn13 via a carboxylate clamp mechanism.
Q38709698SGTA-Dependent Regulation of Hsc70 Promotes Cytosol Entry of Simian Virus 40 from the Endoplasmic Reticulum
Q55657250Structural complexity of the co-chaperone SGTA: a conserved C-terminal region is implicated in dimerization and substrate quality control.
Q42700283Structure and Interactions of the TPR Domain of Sgt2 with Yeast Chaperones and Ybr137wp
Q36824020The Vpu-interacting Protein SGTA Regulates Expression of a Non-glycosylated Tetherin Species

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