BAG6 regulates the quality control of a polytopic ERAD substrate

scientific article published on 7 May 2014

BAG6 regulates the quality control of a polytopic ERAD substrate is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1242/JCS.145565
P932PMC publication ID4075357
P698PubMed publication ID24806960
P5875ResearchGate publication ID262148730

P50authorStephen HighQ30510387
P2093author name stringAishwarya Payapilly
P2860cites workUbiquitin-dependent intramembrane rhomboid protease promotes ERAD of membrane proteinsQ24293182
A ubiquitin ligase-associated chaperone holdase maintains polypeptides in soluble states for proteasome degradationQ24305231
Involvement of Bag6 and the TRC pathway in proteasome assemblyQ38864831
Bat3 promotes the membrane integration of tail-anchored proteinsQ41113412
Endoplasmic reticulum-associated degradation of a degron-containing polytopic membrane proteinQ42060923
Unique proteasome subunit Xrpn10c is a specific receptor for the antiapoptotic ubiquitin-like protein ScytheQ48109396
Regulation of apoptosis by Bat3-enhanced YWK-II/APLP2 protein stability.Q51758768
Anti-rhodopsin monoclonal antibodies of defined specificity: characterization and applicationQ70122085
Human SGT interacts with Bag-6/Bat-3/Scythe and cells with reduced levels of either protein display persistence of few misaligned chromosomes and mitotic arrestQ84001054
SGTA recognizes a noncanonical ubiquitin-like domain in the Bag6-Ubl4A-Trc35 complex to promote endoplasmic reticulum-associated degradationQ24306367
USP13 antagonizes gp78 to maintain functionality of a chaperone in ER-associated degradationQ24320201
Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destructionQ24324602
Ubiquitin-like and ubiquitin-associated domain proteins: significance in proteasomal degradationQ24653719
Gene overexpression: uses, mechanisms, and interpretationQ27001204
Global analysis of protein expression in yeastQ27860658
Comprehensive characterization of genes required for protein folding in the endoplasmic reticulumQ27937991
Human Scythe contains a functional nuclear localization sequence and remains in the nucleus during staurosporine-induced apoptosisQ28190428
Acetylation regulates gluconeogenesis by promoting PEPCK1 degradation via recruiting the UBR5 ubiquitin ligaseQ28242315
Regulatory mechanisms involved in the control of ubiquitin homeostasisQ28280583
A novel, non-apoptotic role for Scythe/BAT3: a functional switch between the pro- and anti-proliferative roles of p21 during the cell cycleQ28385780
BAG-6 is essential for selective elimination of defective proteasomal substratesQ28505838
SGTA antagonizes BAG6-mediated protein triageQ28596609
The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosolQ29618773
Enzymatic blockade of the ubiquitin-proteasome pathwayQ33863563
Out with the old, in with the new? Comparing methods for measuring protein degradationQ33866204
BAT3 guides misfolded glycoproteins out of the endoplasmic reticulumQ34103187
The association of BAG6 with SGTA and tail-anchored proteinsQ34637885
Molecular chaperones and substrate ubiquitination control the efficiency of endoplasmic reticulum-associated degradation.Q34765885
Protein targeting and degradation are coupled for elimination of mislocalized proteinsQ35147351
Ubiquitin receptors and protein quality controlQ36606405
The spatial and temporal organization of ubiquitin networksQ36844591
A ubiquitin-like domain recruits an oligomeric chaperone to a retrotranslocation complex in endoplasmic reticulum-associated degradationQ36947746
Nuclear BAG6-UBL4A-GET4 complex mediates DNA damage signaling and cell death.Q37012498
Extraproteasomal Rpn10 restricts access of the polyubiquitin-binding protein Dsk2 to proteasome.Q37098025
MHC class I molecules are preferentially ubiquitinated on endoplasmic reticulum luminal residues during HRD1 ubiquitin E3 ligase-mediated dislocation.Q37143424
Protein quality control in the cytosol and the endoplasmic reticulum: brothers in arms.Q37802039
Urban planning of the endoplasmic reticulum (ER): how diverse mechanisms segregate the many functions of the ER.Q37901155
Protein quality control in the ER: balancing the ubiquitin checkbookQ37953004
Cellular functions of the DUBsQ37987409
BAG6/BAT3: emerging roles in quality control for nascent polypeptidesQ38070391
Bag6/Bat3/Scythe: a novel chaperone activity with diverse regulatory functions in protein biogenesis and degradation.Q38082449
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issuePt 13
P407language of work or nameEnglishQ1860
P921main subjectquality controlQ827792
P1104number of pages12
P304page(s)2898-2909
P577publication date2014-05-07
P1433published inJournal of Cell ScienceQ1524177
P1476titleBAG6 regulates the quality control of a polytopic ERAD substrate
P478volume127

Reverse relations

cites work (P2860)
Q40215164A conserved island of BAG6/Scythe is related to ubiquitin domains and participates in short hydrophobicity recognition.
Q92270950BAG6 deficiency induces mis-distribution of mitochondrial clusters under depolarization
Q43240834Binding of SGTA to Rpn13 selectively modulates protein quality control
Q64104486Cytoplasmic control of Rab family small GTPases through BAG6
Q46703828Novel characterization of the HSPA2-stabilizing protein BAG6 in human spermatozoa
Q42186480SGTA regulates the cytosolic quality control of hydrophobic substrates
Q26770509Structural and Functional Insights into Small, Glutamine-Rich, Tetratricopeptide Repeat Protein Alpha
Q36824020The Vpu-interacting Protein SGTA Regulates Expression of a Non-glycosylated Tetherin Species
Q92648002The WRB Subunit of the Get3 Receptor is Required for the Correct Integration of its Partner CAML into the ER
Q38775370UBQLN4 recognizes mislocalized transmembrane domain proteins and targets these to proteasomal degradation

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