| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1040893323 |
| P356 | DOI | 10.1038/NATURE10181 |
| P932 | PMC publication ID | 3150218 |
| P698 | PubMed publication ID | 21743475 |
| P5875 | ResearchGate publication ID | 51481012 |
| P50 | author | Ramanujan Shankar Hegde | Q24004353 |
| P2093 | author name string | Ajay Sharma | |
| Malaiyalam Mariappan | |||
| Erik Gutierrez | |||
| Heather D Eshleman | |||
| Tara Hessa | |||
| P2860 | cites work | Multilayered mechanism of CD4 downregulation by HIV-1 Vpu involving distinct ER retention and ERAD targeting steps | Q21131559 |
| A ribosome-associating factor chaperones tail-anchored membrane proteins | Q24293683 | ||
| Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region | Q24301622 | ||
| A ubiquitin ligase-associated chaperone holdase maintains polypeptides in soluble states for proteasome degradation | Q24305231 | ||
| The cytoplasmic Hsp70 chaperone machinery subjects misfolded and endoplasmic reticulum import-incompetent proteins to degradation via the ubiquitin-proteasome system | Q24676115 | ||
| Protein translocation across the endoplasmic reticulum. I. Detection in the microsomal membrane of a receptor for the signal recognition particle | Q24680984 | ||
| Ubr1 and Ubr2 function in a quality control pathway for degradation of unfolded cytosolic proteins | Q27930363 | ||
| Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1 | Q27932129 | ||
| Degradation of misfolded protein in the cytoplasm is mediated by the ubiquitin ligase Ubr1. | Q27939178 | ||
| Identification of a targeting factor for posttranslational membrane protein insertion into the ER | Q28294726 | ||
| BAG-6 is essential for selective elimination of defective proteasomal substrates | Q28505838 | ||
| Reduced translocation of nascent prion protein during ER stress contributes to neurodegeneration | Q30483989 | ||
| Conditions of endoplasmic reticulum stress favor the accumulation of cytosolic prion protein | Q33253898 | ||
| Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway | Q33264756 | ||
| Functional depletion of mahogunin by cytosolically exposed prion protein contributes to neurodegeneration | Q33289413 | ||
| The efficiency of protein compartmentalization into the secretory pathway | Q33564834 | ||
| Signal sequence insufficiency contributes to neurodegeneration caused by transmembrane prion protein | Q33689595 | ||
| Enzymatic blockade of the ubiquitin-proteasome pathway | Q33863563 | ||
| Cotranslational partitioning of nascent prion protein into multiple populations at the translocation channel | Q34274103 | ||
| The signal recognition particle | Q34275497 | ||
| Compartment-restricted biotinylation reveals novel features of prion protein metabolism in vivo | Q34408461 | ||
| In vitro dissection of protein translocation into the mammalian endoplasmic reticulum | Q35065009 | ||
| CHIP: a link between the chaperone and proteasome systems | Q35759085 | ||
| Substrate-specific function of the translocon-associated protein complex during translocation across the ER membrane | Q36325004 | ||
| Retrotranslocation of prion proteins from the endoplasmic reticulum by preventing GPI signal transamidation | Q36796856 | ||
| A signal-anchor sequence stimulates signal recognition particle binding to ribosomes from inside the exit tunnel | Q37068989 | ||
| Photocrosslinking of the signal sequence of nascent preprolactin to the 54-kilodalton polypeptide of the signal recognition particle | Q37407450 | ||
| Delivering proteins for export from the cytosol | Q37420386 | ||
| Protection from cytosolic prion protein toxicity by modulation of protein translocation | Q37671821 | ||
| Protein quality control in the cytosol and the endoplasmic reticulum: brothers in arms. | Q37802039 | ||
| Bat3 promotes the membrane integration of tail-anchored proteins | Q41113412 | ||
| Organelle pH studies using targeted avidin and fluorescein-biotin | Q41724391 | ||
| Signal sequences control gating of the protein translocation channel in a substrate-specific manner | Q42818885 | ||
| Conversion of PrP to a self-perpetuating PrPSc-like conformation in the cytosol | Q44184136 | ||
| Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol | Q44184139 | ||
| Mutant PrP is delayed in its exit from the endoplasmic reticulum, but neither wild-type nor mutant PrP undergoes retrotranslocation prior to proteasomal degradation | Q44381518 | ||
| A substrate-specific inhibitor of protein translocation into the endoplasmic reticulum | Q46562004 | ||
| Diffusional mobility of Golgi proteins in membranes of living cells | Q71160454 | ||
| P433 | issue | 7356 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 394-397 | |
| P577 | publication date | 2011-07-10 | |
| P1433 | published in | Nature | Q180445 |
| P1476 | title | Protein targeting and degradation are coupled for elimination of mislocalized proteins | |
| P478 | volume | 475 |
| Q35751874 | A calmodulin-dependent translocation pathway for small secretory proteins |
| Q40215164 | A conserved island of BAG6/Scythe is related to ubiquitin domains and participates in short hydrophobicity recognition. |
| Q34256996 | A novel BAT3 sequence generated by alternative RNA splicing of exon 11B displays cell type-specific expression and impacts on subcellular localization |
| Q38040951 | A portrait of the GET pathway as a surprisingly complicated young man. |
| Q24305231 | A ubiquitin ligase-associated chaperone holdase maintains polypeptides in soluble states for proteasome degradation |
| Q36947746 | A ubiquitin-like domain recruits an oligomeric chaperone to a retrotranslocation complex in endoplasmic reticulum-associated degradation |
| Q38093231 | All roads lead to Rome (but some may be harder to travel): SRP-independent translocation into the endoplasmic reticulum |
| Q46325087 | Assembly and Function of Heterotypic Ubiquitin Chains in Cell-Cycle and Protein Quality Control |
| Q38168708 | BAG-6, a jack of all trades in health and disease |
| Q84597133 | BAG6 'mops up' mislocalized proteins |
| Q92479518 | BAG6 contributes to glucose uptake by supporting the cell surface translocation of the glucose transporter GLUT4 |
| Q92270950 | BAG6 deficiency induces mis-distribution of mitochondrial clusters under depolarization |
| Q41482461 | BAG6 regulates the quality control of a polytopic ERAD substrate |
| Q38070391 | BAG6/BAT3: emerging roles in quality control for nascent polypeptides |
| Q100157394 | BAG6:GET4:UBL4A binds mislocalized membrane protein:SGTA and ASNA1:ATP |
| Q34103187 | BAT3 guides misfolded glycoproteins out of the endoplasmic reticulum |
| Q24311324 | Bag6 complex contains a minimal tail-anchor-targeting module and a mock BAG domain |
| Q38082449 | Bag6/Bat3/Scythe: a novel chaperone activity with diverse regulatory functions in protein biogenesis and degradation. |
| Q43240834 | Binding of SGTA to Rpn13 selectively modulates protein quality control |
| Q38664342 | Charged residues next to transmembrane regions revisited: "Positive-inside rule" is complemented by the "negative inside depletion/outside enrichment rule" |
| Q38864129 | Comparative Haploid Genetic Screens Reveal Divergent Pathways in the Biogenesis and Trafficking of Glycophosphatidylinositol-Anchored Proteins. |
| Q33628850 | Control of mitochondrial biogenesis and function by the ubiquitin-proteasome system |
| Q51830754 | Cotransin induces accumulation of a cytotoxic clusterin variant that cotranslationally rerouted to the cytosol. |
| Q64104486 | Cytoplasmic control of Rab family small GTPases through BAG6 |
| Q24300029 | Cytosolic quality control of mislocalized proteins requires RNF126 recruitment to Bag6 |
| Q52424984 | Distinct types of protease systems are involved in homeostasis regulation of mitochondrial morphology via balanced fusion and fission. |
| Q36091833 | Efficient secretion of small proteins in mammalian cells relies on Sec62-dependent posttranslational translocation |
| Q34294233 | Elevation of proteasomal substrate levels sensitizes cells to apoptosis induced by inhibition of proteasomal deubiquitinases |
| Q44897873 | Elimination of a signal sequence-uncleaved form of defective HLA protein through BAG6. |
| Q26866138 | Endoplasmic reticulum targeting and insertion of tail-anchored membrane proteins by the GET pathway |
| Q64255510 | Genome-Wide Identification and Evaluation of New Reference Genes for Gene Expression Analysis Under Temperature and Salinity Stresses in |
| Q36731436 | Get3 is a holdase chaperone and moves to deposition sites for aggregated proteins when membrane targeting is blocked |
| Q90424090 | Guiding tail-anchored membrane proteins to the endoplasmic reticulum in a chaperone cascade |
| Q40209893 | HLA-B-associated transcript 3 (Bat3/Scythe) negatively regulates Smad phosphorylation in BMP signaling |
| Q27022124 | HLA-dependent tumour development: a role for tumour associate macrophages? |
| Q42383178 | Human Sex Determination at the Edge of Ambiguity: INHERITED XY SEX REVERSAL DUE TO ENHANCED UBIQUITINATION AND PROTEASOMAL DEGRADATION OF A MASTER TRANSCRIPTION FACTOR. |
| Q47255663 | In vitro reconstitution of translational arrest pathways |
| Q41558826 | Inhibition of protein translocation at the endoplasmic reticulum promotes activation of the unfolded protein response |
| Q38864831 | Involvement of Bag6 and the TRC pathway in proteasome assembly |
| Q28675845 | Listerin-dependent nascent protein ubiquitination relies on ribosome subunit dissociation |
| Q58583775 | Lost in Translation: Ribosome-Associated mRNA and Protein Quality Controls |
| Q55044914 | MARCH6 and TRC8 facilitate the quality control of cytosolic and tail-anchored proteins. |
| Q46465153 | Mechanisms of Tail-Anchored Membrane Protein Targeting and Insertion. |
| Q42292851 | Mechanistic basis for a molecular triage reaction |
| Q34179638 | Membrane protein insertion at the endoplasmic reticulum |
| Q34095072 | Metabolism of minor isoforms of prion proteins: Cytosolic prion protein and transmembrane prion protein |
| Q39612063 | Mice lacking WRB reveal differential biogenesis requirements of tail-anchored proteins in vivo |
| Q64290441 | Misfolded GPI-anchored proteins are escorted through the secretory pathway by ER-derived factors |
| Q26828990 | Molecular chaperones in targeting misfolded proteins for ubiquitin-dependent degradation |
| Q55114046 | Molecular mechanism of ER stress-induced pre-emptive quality control involving association of the translocon, Derlin-1, and HRD1. |
| Q34343289 | Msp1/ATAD1 maintains mitochondrial function by facilitating the degradation of mislocalized tail-anchored proteins |
| Q41869462 | Msp1: patrolling mitochondria for lost proteins |
| Q47108141 | Multiple pathways facilitate the biogenesis of mammalian tail-anchored proteins |
| Q40778656 | Multiple selection filters ensure accurate tail-anchored membrane protein targeting |
| Q98878656 | Multiplexed measurement of variant abundance and activity reveals VKOR topology, active site and human variant impact |
| Q37297662 | Nodular lymphocyte predominant hodgkin lymphoma and T cell/histiocyte rich large B cell lymphoma--endpoints of a spectrum of one disease? |
| Q46703828 | Novel characterization of the HSPA2-stabilizing protein BAG6 in human spermatozoa |
| Q42224037 | Overexpression of BAT3 alleviates prion protein fragment PrP106-126-induced neuronal apoptosis. |
| Q28306492 | Perilous journey: a tour of the ubiquitin-proteasome system |
| Q37047936 | Peroxin-dependent targeting of a lipid-droplet-destined membrane protein to ER subdomains |
| Q38900355 | Porcine reproductive and respiratory syndrome virus nonstructural protein 2 (nsp2) topology and selective isoform integration in artificial membranes |
| Q47305042 | Positive charge in the n-region of the signal peptide contributes to efficient post-translational translocation of small secretory preproteins |
| Q46498597 | PrP-containing aggresomes are cytosolic components of an ER quality control mechanism. |
| Q33743186 | Predicting the targeting of tail-anchored proteins to subcellular compartments in mammalian cells. |
| Q36224548 | Proteasomal degradation of preemptive quality control (pQC) substrates is mediated by an AIRAPL-p97 complex |
| Q37953004 | Protein quality control in the ER: balancing the ubiquitin checkbook |
| Q38954697 | Proteome complexity and the forces that drive proteome imbalance. |
| Q90740558 | Quality Control of Orphaned Proteins |
| Q34244144 | Reconstitution of a minimal ribosome-associated ubiquitination pathway with purified factors |
| Q39430414 | Repair or destruction-an intimate liaison between ubiquitin ligases and molecular chaperones in proteostasis |
| Q39185522 | Rescue of impaired NK cell activity in hodgkin lymphoma with bispecific antibodies in vitro and in patients |
| Q90864188 | Ribosomal mistranslation leads to silencing of the unfolded protein response and increased mitochondrial biogenesis |
| Q28596609 | SGTA antagonizes BAG6-mediated protein triage |
| Q90678120 | SGTA associates with nascent membrane protein precursors |
| Q42371745 | SGTA interacts with the proteasomal ubiquitin receptor Rpn13 via a carboxylate clamp mechanism. |
| Q24306367 | SGTA recognizes a noncanonical ubiquitin-like domain in the Bag6-Ubl4A-Trc35 complex to promote endoplasmic reticulum-associated degradation |
| Q42186480 | SGTA regulates the cytosolic quality control of hydrophobic substrates |
| Q37374069 | Secretory protein profiling reveals TNF-α inactivation by selective and promiscuous Sec61 modulators |
| Q24338887 | Signal-peptide-mediated translocation is regulated by a p97-AIRAPL complex |
| Q28545114 | Solution structure of the SGTA dimerisation domain and investigation of its interactions with the ubiquitin-like domains of BAG6 and UBL4A |
| Q42111753 | Spatial control of lipid droplet proteins by the ERAD ubiquitin ligase Doa10. |
| Q51036230 | Specific inhibition of hamster prion protein translocation by the dodecadepsipeptide valinomycin. |
| Q26770509 | Structural and Functional Insights into Small, Glutamine-Rich, Tetratricopeptide Repeat Protein Alpha |
| Q42011073 | Structural and functional insights into the E3 ligase, RNF126. |
| Q46122220 | Structural basis for regulation of the nucleo-cytoplasmic distribution of Bag6 by TRC35. |
| Q39582237 | Structural features within the nascent chain regulate alternative targeting of secretory proteins to mitochondria |
| Q42700283 | Structure and Interactions of the TPR Domain of Sgt2 with Yeast Chaperones and Ybr137wp |
| Q35064391 | Structure and assembly pathway of the ribosome quality control complex |
| Q39474998 | Structure of a BAG6 (Bcl-2-associated athanogene 6)-Ubl4a (ubiquitin-like protein 4a) complex reveals a novel binding interface that functions in tail-anchored protein biogenesis |
| Q27675050 | Structures of the Sgt2/SGTA Dimerization Domain with the Get5/UBL4A UBL Domain Reveal an Interaction that Forms a Conserved Dynamic Interface |
| Q41176440 | Structures of the scanning and engaged states of the mammalian SRP-ribosome complex |
| Q35915784 | Subcellular Fractionation Analysis of the Extraction of Ubiquitinated Polytopic Membrane Substrate during ER-Associated Degradation |
| Q36242781 | TRC40 can deliver short secretory proteins to the Sec61 translocon |
| Q36655456 | Tail-anchored PEX26 targets peroxisomes via a PEX19-dependent and TRC40-independent class I pathway |
| Q37140792 | Tail-anchored membrane protein insertion into the endoplasmic reticulum |
| Q47292355 | The ER membrane protein complex is a transmembrane domain insertase |
| Q50908561 | The Role of LORELEI in Pollen Tube Reception at the Interface of the Synergid Cell and Pollen Tube Requires the Modified Eight-Cysteine Motif and the Receptor-Like Kinase FERONIA. |
| Q47586836 | The Sec61/SecY complex is inherently deficient in translocating intrinsically disordered proteins |
| Q52312170 | The VCP-UBXN1 complex mediates triage of ubiquitylated cytosolic proteins bound to the BAG6 complex. |
| Q36824020 | The Vpu-interacting Protein SGTA Regulates Expression of a Non-glycosylated Tetherin Species |
| Q92648002 | The WRB Subunit of the Get3 Receptor is Required for the Correct Integration of its Partner CAML into the ER |
| Q34637885 | The association of BAG6 with SGTA and tail-anchored proteins |
| Q35110985 | The chaperone BAG6 captures dislocated glycoproteins in the cytosol. |
| Q35986793 | The complex process of GETting tail-anchored membrane proteins to the ER. |
| Q38419066 | The emerging role of calcium-modulating cyclophilin ligand in posttranslational insertion of tail-anchored proteins into the endoplasmic reticulum membrane |
| Q49358535 | The peroxisome biogenesis factors posttranslationally target reticulon homology domain-containing proteins to the endoplasmic reticulum membrane |
| Q34029353 | Towards a systems understanding of MHC class I and MHC class II antigen presentation. |
| Q55235796 | Transmembrane E3 ligase RNF183 mediates ER stress-induced apoptosis by degrading Bcl-xL. |
| Q47993287 | UBE2O is a quality control factor for orphans of multiprotein complexes. |
| Q38775370 | UBQLN4 recognizes mislocalized transmembrane domain proteins and targets these to proteasomal degradation |
| Q24320201 | USP13 antagonizes gp78 to maintain functionality of a chaperone in ER-associated degradation |
| Q41953002 | Ubiquilins Chaperone and Triage Mitochondrial Membrane Proteins for Degradation. |
| Q33797100 | VAPB/ALS8 interacts with FFAT-like proteins including the p97 cofactor FAF1 and the ASNA1 ATPase |
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