SGTA associates with nascent membrane protein precursors

scientific article published on 25 March 2020

SGTA associates with nascent membrane protein precursors is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.15252/EMBR.201948835
P932PMC publication ID7202230
P698PubMed publication ID32216016

P50authorStephen HighQ30510387
Pawel LeznickiQ88446241
P2860cites workA ribosome-associating factor chaperones tail-anchored membrane proteinsQ24293683
Cytosolic quality control of mislocalized proteins requires RNF126 recruitment to Bag6Q24300029
SGTA recognizes a noncanonical ubiquitin-like domain in the Bag6-Ubl4A-Trc35 complex to promote endoplasmic reticulum-associated degradationQ24306367
Bag6 complex contains a minimal tail-anchor-targeting module and a mock BAG domainQ24311324
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Cdc48/p97 promotes degradation of aberrant nascent polypeptides bound to the ribosomeQ27939735
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Small glutamine-rich tetratricopeptide repeat-containing protein is composed of three structural units with distinct functionsQ28572700
SGTA antagonizes BAG6-mediated protein triageQ28596609
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Trigger factor binds to ribosome-signal-recognition particle (SRP) complexes and is excluded by binding of the SRP receptorQ34330256
Topogenesis of membrane proteins: determinants and dynamics.Q34353219
PUROMYCIN INHIBITION OF PROTEIN SYNTHESIS: INCORPORATION OF PUROMYCIN INTO PEPTIDE CHAINSQ34402144
Association of protein biogenesis factors at the yeast ribosomal tunnel exit is affected by the translational status and nascent polypeptide sequenceQ34603048
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Protein targeting and degradation are coupled for elimination of mislocalized proteinsQ35147351
The ribosome quality control pathway can access nascent polypeptides stalled at the Sec61 transloconQ35717767
Aberrant substrate engagement of the ER translocon triggers degradation by the Hrd1 ubiquitin ligase.Q36027390
The interaction of the chaperonin tailless complex polypeptide 1 (TCP1) ring complex (TRiC) with ribosome-bound nascent chains examined using photo-cross-linkingQ36327627
SRP keeps polypeptides translocation-competent by slowing translation to match limiting ER-targeting sitesQ36726739
A cotranslational ubiquitination pathway for quality control of misfolded proteinsQ36844049
A signal-anchor sequence stimulates signal recognition particle binding to ribosomes from inside the exit tunnelQ37068989
Probing the molecular environment of translocating polypeptide chains by cross-linking.Q37479657
The ribosome as a platform for co-translational processing, folding and targeting of newly synthesized proteinsQ37506110
Ribosome-associated chaperones as key players in proteostasisQ38002646
Co-translational targeting and translocation of proteins to the endoplasmic reticulum.Q38088451
A cytosolic chaperone complexes with dynamic membrane J-proteins and mobilizes a nonenveloped virus out of the endoplasmic reticulum.Q38542913
A biochemical analysis of the constraints of tail-anchored protein biogenesis.Q38780873
On the road to nowhere: cross-talk between post-translational protein targeting and cytosolic quality control.Q38860895
Global profiling of SRP interaction with nascent polypeptides.Q39529450
Cotranslational Intersection between the SRP and GET Targeting Pathways to the Endoplasmic Reticulum of Saccharomyces cerevisiaeQ39647451
The cotranslational contacts between ribosome-bound nascent polypeptides and the subunits of the hetero-oligomeric chaperonin TRiC probed by photocross-linkingQ40414710
Systematic probing of the environment of a translocating secretory protein during translocation through the ER membraneQ40792995
The affinity of signal recognition particle for presecretory proteins is dependent on nascent chain lengthQ41107376
Bat3 promotes the membrane integration of tail-anchored proteinsQ41113412
Direct probing of the interaction between the signal sequence of nascent preprolactin and the signal recognition particle by specific cross-linkingQ41514326
Principles of cotranslational ubiquitination and quality control at the ribosomeQ41861567
Ubiquilins Chaperone and Triage Mitochondrial Membrane Proteins for Degradation.Q41953002
SGTA regulates the cytosolic quality control of hydrophobic substratesQ42186480
Mechanistic basis for a molecular triage reactionQ42292851
Binding of SGTA to Rpn13 selectively modulates protein quality controlQ43240834
Mechanisms of Tail-Anchored Membrane Protein Targeting and Insertion.Q46465153
Multiple pathways facilitate the biogenesis of mammalian tail-anchored proteinsQ47108141
The ER membrane protein complex is a transmembrane domain insertaseQ47292355
hSnd2 protein represents an alternative targeting factor to the endoplasmic reticulum in human cells.Q47870590
Dissecting the physiological role of selective transmembrane-segment retention at the ER transloconQ47876109
Defining the physiological role of SRP in protein-targeting efficiency and specificity.Q48216182
Signal recognition particle binds to ribosome-bound signal sequences with fluorescence-detected subnanomolar affinity that does not diminish as the nascent chain lengthens.Q52842432
The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins.Q55473761
Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein importQ58740862
Signal-sequence recognition by an Escherichia coli ribonucleoprotein complexQ59096822
EMC Is Required to Initiate Accurate Membrane Protein TopogenesisQ59800191
Biogenesis of Polytopic Membrane Proteins: Membrane Segments of P-glycoprotein Sequentially Translocate To Span the ER Membrane†Q62108911
Reinitiation of protein translocation across the endoplasmic reticulum membrane for the topogenesis of multispanning membrane proteinsQ71069998
Site-specific photocross-linking reveals that Sec61p and TRAM contact different regions of a membrane-inserted signal sequenceQ72639603
Substrate relay in an Hsp70-cochaperone cascade safeguards tail-anchored membrane protein targetingQ89421739
Mechanisms and functions of ribosome-associated protein quality controlQ92802742
P921main subjectmembrane proteinQ423042
P304page(s)e48835
P577publication date2020-03-25
P1433published inEMBO ReportsQ5323356
P1476titleSGTA associates with nascent membrane protein precursors