Mechanisms of Tail-Anchored Membrane Protein Targeting and Insertion.

scientific article published in October 2017

Mechanisms of Tail-Anchored Membrane Protein Targeting and Insertion. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1146/ANNUREV-CELLBIO-100616-060839
P932PMC publication ID6343671
P698PubMed publication ID28992441

P50authorUn Seng ChioQ60371755
P2093author name stringHyunju Cho
Shu-Ou Shan
P2860cites workMolecular machinery for insertion of tail-anchored membrane proteins into the endoplasmic reticulum membrane in mammalian cellsQ87414726
FISSION1A, an Arabidopsis tail-anchored protein, is localized to three subcellular compartmentsQ87496591
How YidC inserts and folds proteins across a membraneQ87816862
Targeting of the tail-anchored peroxisomal membrane proteins PEX26 and PEX15 occurs through C-terminal PEX19-binding sitesQ24292960
A ribosome-associating factor chaperones tail-anchored membrane proteinsQ24293683
Cytosolic quality control of mislocalized proteins requires RNF126 recruitment to Bag6Q24300029
A ubiquitin ligase-associated chaperone holdase maintains polypeptides in soluble states for proteasome degradationQ24305231
SGTA recognizes a noncanonical ubiquitin-like domain in the Bag6-Ubl4A-Trc35 complex to promote endoplasmic reticulum-associated degradationQ24306367
Structural basis for docking of peroxisomal membrane protein carrier Pex19p onto its receptor Pex3pQ24307906
Bag6 complex contains a minimal tail-anchor-targeting module and a mock BAG domainQ24311324
The peroxisomal receptor Pex19p forms a helical mPTS recognition domainQ24318137
Transport route for synaptobrevin via a novel pathway of insertion into the endoplasmic reticulum membraneQ24568369
Structural and Functional Insights into Small, Glutamine-Rich, Tetratricopeptide Repeat Protein AlphaQ26770509
Peroxisomes take shapeQ27027175
Association between the intrinsically disordered protein PEX19 and PEX3Q27318204
Structure of TPR domain-peptide complexes: critical elements in the assembly of the Hsp70-Hsp90 multichaperone machineQ27622332
The structural basis of tail-anchored membrane protein recognition by Get3Q27656979
Model for eukaryotic tail-anchored protein binding based on the structure of Get3Q27657172
Structural insights into tail-anchored protein binding and membrane insertion by Get3Q27658386
The Crystal Structures of Yeast Get3 Suggest a Mechanism for Tail-Anchored Protein Membrane InsertionQ27658420
Crystal Structure of Get4-Get5 Complex and Its Interactions with Sgt2, Get3, and Ydj1Q27659241
The structure of Get4 reveals an alpha-solenoid fold adapted for multiple interactions in tail-anchored protein biogenesisQ27660129
Insights into Peroxisome Function from the Structure of PEX3 in Complex with a Soluble Fragment of PEX19Q27662365
Structural characterization of the Get4/Get5 complex and its interaction with Get3Q27662391
Structural Basis for Tail-Anchored Membrane Protein Biogenesis by the Get3-Receptor ComplexQ27670623
A Structural Model of the Sgt2 Protein and Its Interactions with Chaperones and the Get4/Get5 ComplexQ27671664
The mechanism of membrane-associated steps in tail-anchored protein insertionQ27671975
Structures of the Sgt2/SGTA Dimerization Domain with the Get5/UBL4A UBL Domain Reveal an Interaction that Forms a Conserved Dynamic InterfaceQ27675050
Structure of the Sgt2/Get5 complex provides insights into GET-mediated targeting of tail-anchored membrane proteinsQ27675806
Get5 Carboxyl-terminal Domain Is a Novel Dimerization Motif That Tethers an Extended Get4/Get5 ComplexQ27676804
Get1 stabilizes an open dimer conformation of get3 ATPase by binding two distinct interfacesQ27681084
Crystal structure of ATP-bound Get3–Get4–Get5 complex reveals regulation of Get3 by Get4Q27683285
Structure of the Sgt2 dimerization domain complexed with the Get5 UBL domain involved in the targeting of tail-anchored membrane proteins to the endoplasmic reticulumQ27686994
A Chaperone Cascade Sorts Proteins for Posttranslational Membrane Insertion into the Endoplasmic ReticulumQ27931629
SGT2 and MDY2 interact with molecular chaperone YDJ1 in Saccharomyces cerevisiaeQ27931740
The GET complex mediates insertion of tail-anchored proteins into the ER membraneQ27932687
The conserved AAA-ATPase Msp1 confers organelle specificity to tail-anchored proteinsQ27933340
Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profileQ27935813
Comprehensive characterization of genes required for protein folding in the endoplasmic reticulumQ27937991
Peroxisomal membrane proteins insert into the endoplasmic reticulumQ27939149
Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexesQ27939264
Bipartite signals mediate subcellular targeting of tail-anchored membrane proteins in Saccharomyces cerevisiaeQ27939705
Identification of a targeting factor for posttranslational membrane protein insertion into the ERQ28294726
Solution structure of the SGTA dimerisation domain and investigation of its interactions with the ubiquitin-like domains of BAG6 and UBL4AQ28545114
SGTA antagonizes BAG6-mediated protein triageQ28596609
Specific targeting of proteins to outer envelope membranes of endosymbiotic organelles, chloroplasts, and mitochondriaQ28657937
The SND proteins constitute an alternative targeting route to the endoplasmic reticulumQ33364351
Hydrophobic profiles of the tail anchors in SLMAP dictate subcellular targetingQ33470754
Distinct pathways mediate the sorting of tail-anchored proteins to the plastid outer envelopeQ33564134
Targeting of tail-anchored proteins to yeast mitochondria in vivoQ33865072
Transmembrane topogenesis of a tail-anchored protein is modulated by membrane lipid compositionQ33899633
Interaction of modified tail-anchored proteins with liposomes: effect of extensions of hydrophilic segment at the COOH-terminus of holo-cytochromes b₅.Q34090103
Ribosome fidelity: tRNA discrimination, proofreading and induced fit.Q34134651
A class of membrane proteins with a C-terminal anchorQ34290936
Msp1/ATAD1 maintains mitochondrial function by facilitating the degradation of mislocalized tail-anchored proteinsQ34343289
A vesicle carrier that mediates peroxisome protein traffic from the endoplasmic reticulumQ34411335
Differential gradients of interaction affinities drive efficient targeting and recycling in the GET pathwayQ34581057
The association of BAG6 with SGTA and tail-anchored proteinsQ34637885
Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranesQ34719604
WRB and CAML are necessary and sufficient to mediate tail-anchored protein targeting to the ER membraneQ35083500
The Get1/2 transmembrane complex is an endoplasmic-reticulum membrane protein insertaseQ35127549
Protein targeting and degradation are coupled for elimination of mislocalized proteinsQ35147351
Nucleotide-dependent mechanism of Get3 as elucidated from free energy calculationsQ35974266
The complex process of GETting tail-anchored membrane proteins to the ER.Q35986793
Unassisted translocation of large polypeptide domains across phospholipid bilayersQ36119397
Mechanism of Assembly of a Substrate Transfer Complex during Tail-anchored Protein TargetingQ36444249
Tail-anchored PEX26 targets peroxisomes via a PEX19-dependent and TRC40-independent class I pathwayQ36655456
Precise timing of ATPase activation drives targeting of tail-anchored proteinsQ36835510
Tail-anchored membrane protein insertion into the endoplasmic reticulumQ37140792
Distinct targeting pathways for the membrane insertion of tail-anchored (TA) proteinsQ37307105
A mutant cytochrome b5 with a lengthened membrane anchor escapes from the endoplasmic reticulum and reaches the plasma membraneQ37632959
Signal recognition particle: an essential protein-targeting machineQ38081948
Tail-anchored Protein Insertion in Mammals: FUNCTION AND RECIPROCAL INTERACTIONS OF THE TWO SUBUNITS OF THE TRC40 RECEPTOR.Q38768375
The mechanism of tail-anchored protein insertion into the ER membraneQ39502102
Characterization of signal that directs C-tail-anchored proteins to mammalian mitochondrial outer membraneQ39586462
The role of cytosolic proteins in the insertion of tail-anchored proteins into phospholipid bilayers.Q39837187
Transmembrane domain-dependent partitioning of membrane proteins within the endoplasmic reticulumQ39994820
Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargoQ40031008
Multiple selection filters ensure accurate tail-anchored membrane protein targetingQ40778656
Cytosolic factor- and TOM-independent import of C-tail-anchored mitochondrial outer membrane proteinsQ41092707
Hydrophobic handoff for direct delivery of peroxisome tail-anchored proteins.Q41679263
Intra-ER sorting of the peroxisomal membrane protein Pex3 relies on its luminal domainQ41775470
New insights into the targeting of a subset of tail-anchored proteins to the outer mitochondrial membraneQ41995686
SGTA regulates the cytosolic quality control of hydrophobic substratesQ42186480
WRB is the receptor for TRC40/Asna1-mediated insertion of tail-anchored proteins into the ER membraneQ42280602
Mechanistic basis for a molecular triage reactionQ42292851
SGTA interacts with the proteasomal ubiquitin receptor Rpn13 via a carboxylate clamp mechanism.Q42371745
A precursor-specific role for Hsp40/Hsc70 during tail-anchored protein integration at the endoplasmic reticulumQ43125499
Binding of SGTA to Rpn13 selectively modulates protein quality controlQ43240834
Integration of tail-anchored proteins into the mitochondrial outer membrane does not require any known import componentsQ44066667
Peroxisomal ascorbate peroxidase resides within a subdomain of rough endoplasmic reticulum in wild-type Arabidopsis cellsQ44477483
Post-Translational Targeting of a Tail-Anchored Green Fluorescent Protein to the Endolpasmic ReticulumQ44619407
Asna1/TRC40-mediated membrane insertion of tail-anchored proteinsQ44964243
Retention of cytochrome b5 in the endoplasmic reticulum is transmembrane and luminal domain-dependentQ47724611
Novel targeting signals mediate the sorting of different isoforms of the tail-anchored membrane protein cytochrome b5 to either endoplasmic reticulum or mitochondriaQ48168157
AKR2A-mediated import of chloroplast outer membrane proteins is essential for chloroplast biogenesis.Q53505483
The sorting signals for peroxisomal membrane-bound ascorbate peroxidase are within its C-terminal tailQ73626482
Charged amino acids at the carboxyl-terminal portions determine the intracellular locations of two isoforms of cytochrome b5Q77545117
Post-translational integration of tail-anchored proteins is facilitated by defined molecular chaperonesQ80210461
P921main subjectmembrane proteinQ423042
P304page(s)417-438
P577publication date2017-10-01
P1433published inAnnual Review of Cell and Developmental BiologyQ4497277
P1476titleMechanisms of Tail-Anchored Membrane Protein Targeting and Insertion
P478volume33

Reverse relations

cites work (P2860)
Q58608852A bacteria-derived tail anchor localizes to peroxisomes in yeast and mammalian cells
Q90730458Distinct Requirements for Tail-Anchored Membrane Protein Biogenesis in Escherichia coli
Q64244254Folding and Misfolding of Human Membrane Proteins in Health and Disease: From Single Molecules to Cellular Proteostasis
Q90424090Guiding tail-anchored membrane proteins to the endoplasmic reticulum in a chaperone cascade
Q91727097In vitro Assays for Targeting and Insertion of Tail-Anchored Proteins Into the ER Membrane
Q100235790Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Q89766695Proteins containing ubiquitin-like (Ubl) domains not only bind to 26S proteasomes but also induce their activation
Q90678120SGTA associates with nascent membrane protein precursors
Q92648002The WRB Subunit of the Get3 Receptor is Required for the Correct Integration of its Partner CAML into the ER
Q95851107The architecture of EMC reveals a path for membrane protein insertion

Search more.