scholarly article | Q13442814 |
P50 | author | Robert Jackson | Q85237127 |
Ingeborg Zehbe | Q109301855 | ||
Sean Cuninghame | Q117231623 | ||
P2860 | cites work | Hallmarks of Cancer: The Next Generation | Q22252312 |
Structures and Proton-Pumping Strategies of Mitochondrial Respiratory Enzymes | Q22255650 | ||
A conserved family of prolyl-4-hydroxylases that modify HIF | Q24291794 | ||
Epstein-Barr virus immortalization of human B-cells leads to stabilization of hypoxia-induced factor 1 alpha, congruent with the Warburg effect | Q24294513 | ||
Twist and epithelial-mesenchymal transition are induced by the EBV oncoprotein latent membrane protein 1 and are associated with metastatic nasopharyngeal carcinoma | Q24298635 | ||
SUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxia | Q24299542 | ||
Metastasis-associated protein 1 enhances stability of hypoxia-inducible factor-1alpha protein by recruiting histone deacetylase 1. | Q24306316 | ||
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension | Q24307473 | ||
Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1 | Q24316075 | ||
The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53 | Q24317677 | ||
IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway | Q24337225 | ||
Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1alpha | Q24338422 | ||
Lysosomal cysteine proteases: facts and opportunities | Q24535678 | ||
Understanding the Warburg effect: the metabolic requirements of cell proliferation | Q24604760 | ||
miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis | Q24613599 | ||
HIF-1: upstream and downstream of cancer metabolism | Q24647482 | ||
Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8) | Q24650427 | ||
Why do viruses cause cancer? Highlights of the first century of human tumour virology | Q37811898 | ||
Diverse roles of hepatitis B virus in liver cancer | Q38020667 | ||
Oxygen-independent regulation of HIF-1: novel involvement of PI3K/AKT/mTOR pathway in cancer | Q38072462 | ||
Disrupting proton dynamics and energy metabolism for cancer therapy | Q38130850 | ||
bHLH-PAS proteins in cancer | Q38164994 | ||
The transcription factor Egr1 regulates the HIF-1alpha gene during hypoxia. | Q38290578 | ||
Nucleotide sequence, chromosomal assignment and mRNA expression of mouse hypoxia-inducible factor-1 alpha | Q38356865 | ||
Hepatitis B virus X protein induces angiogenesis by stabilizing hypoxia-inducible factor-1alpha | Q38518574 | ||
A dual role for hypoxia inducible factor-1α in the hepatitis C virus lifecycle and hepatoma migration | Q39426654 | ||
Overexpression of MMP-9 and HIF-1α in Breast Cancer Cells under Hypoxic Conditions | Q39716859 | ||
Role of the HBx oncoprotein in carbonic anhydrase 9 induction | Q39768872 | ||
Comprehensive analysis of the independent effect of twist and snail in promoting metastasis of hepatocellular carcinoma. | Q39788635 | ||
Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH. | Q39899643 | ||
Epstein-Barr virus-encoded EBNA1 modulates the AP-1 transcription factor pathway in nasopharyngeal carcinoma cells and enhances angiogenesis in vitro | Q39927855 | ||
Kaposi's sarcoma-associated herpesvirus viral IFN regulatory factor 3 stabilizes hypoxia-inducible factor-1 alpha to induce vascular endothelial growth factor expression | Q40002571 | ||
Roles for hypoxia-regulated genes during cervical carcinogenesis: somatic evolution during the hypoxia-glycolysis-acidosis sequence | Q40041397 | ||
A potential alpha-helix motif in the amino terminus of LANA encoded by Kaposi's sarcoma-associated herpesvirus is critical for nuclear accumulation of HIF-1alpha in normoxia | Q40106826 | ||
Activation of hypoxia-inducible factor 1 in human T-cell leukaemia virus type 1-infected cell lines and primary adult T-cell leukaemia cells | Q40118264 | ||
Higher expression and activity of metalloproteinases in human cervical carcinoma cell lines is associated with HPV presence. | Q40196754 | ||
EBV latent membrane protein 1 up-regulates hypoxia-inducible factor 1alpha through Siah1-mediated down-regulation of prolyl hydroxylases 1 and 3 in nasopharyngeal epithelial cells | Q40219046 | ||
Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis | Q36584906 | ||
Glucose metabolism and cancer | Q36625786 | ||
Virus-specific mechanisms of carcinogenesis in hepatitis C virus associated liver cancer | Q36812745 | ||
HIF-1 mediates the Warburg effect in clear cell renal carcinoma | Q36841614 | ||
Papillomavirus E6 and E7 proteins and their cellular targets | Q36992007 | ||
NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha | Q37158836 | ||
Hypoxia-specific stabilization of HIF-1alpha by human papillomaviruses | Q37171664 | ||
Increased expression of ErbB-2 in liver is associated with hepatitis B x antigen and shorter survival in patients with liver cancer | Q37349973 | ||
Signal transducer and activator of transcription 3 is required for hypoxia-inducible factor-1alpha RNA expression in both tumor cells and tumor-associated myeloid cells | Q37417836 | ||
Regulation of hypoxia-inducible factor-1alpha by NF-kappaB | Q24657260 | ||
Clonal integration of a polyomavirus in human Merkel cell carcinoma | Q24657675 | ||
Hepatitis C Virus Stabilizes Hypoxia-Inducible Factor 1 and Stimulates the Synthesis of Vascular Endothelial Growth Factor | Q27481487 | ||
Temporal Proteome and Lipidome Profiles Reveal Hepatitis C Virus-Associated Reprogramming of Hepatocellular Metabolism and Bioenergetics | Q27490520 | ||
Hepatitis C Virus-Linked Mitochondrial Dysfunction Promotes Hypoxia-Inducible Factor 1 -Mediated Glycolytic Adaptation | Q27490543 | ||
Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer | Q27824855 | ||
Targeting HIF-1 for cancer therapy | Q27860504 | ||
Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function | Q28140184 | ||
HIF1A gene transcription is dependent on a core promoter sequence encompassing activating and inhibiting sequences located upstream from the transcription initiation site and cis elements located within the 5'UTR | Q28140700 | ||
HIF-1: mediator of physiological and pathophysiological responses to hypoxia | Q28140835 | ||
HIF-1, O(2), and the 3 PHDs: how animal cells signal hypoxia to the nucleus | Q28191456 | ||
Carbonic anhydrase IX expression, a novel surrogate marker of tumor hypoxia, is associated with a poor prognosis in non-small-cell lung cancer | Q28206439 | ||
Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch | Q28217194 | ||
Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1α | Q28259513 | ||
Histone deacetylase 7 associates with hypoxia-inducible factor 1alpha and increases transcriptional activity | Q28274440 | ||
Pathogenic mechanisms in HBV- and HCV-associated hepatocellular carcinoma | Q28284012 | ||
In vivo expression of mRNAs encoding hypoxia-inducible factor 1 | Q28286675 | ||
Energy boost: the Warburg effect returns in a new theory of cancer | Q28298486 | ||
Hypoxia-inducible factor-1 alpha is regulated at the post-mRNA level | Q28303316 | ||
Molecular mechanisms and clinical applications of angiogenesis | Q29547314 | ||
Microenvironmental regulation of metastasis | Q29547660 | ||
Papillomaviruses and cancer: from basic studies to clinical application | Q29614745 | ||
Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways | Q29615855 | ||
THE METABOLISM OF TUMORS IN THE BODY | Q29616202 | ||
Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing | Q29617570 | ||
Tumor metastasis: mechanistic insights and clinical challenges | Q29617676 | ||
Epidemiology of Viral Hepatitis and Hepatocellular Carcinoma | Q29617918 | ||
Epstein-Barr virus: 40 years on | Q29617969 | ||
Global burden of cancers attributable to infections in 2008: a review and synthetic analysis | Q29620303 | ||
The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice | Q29620765 | ||
EC5S ubiquitin complex is recruited by KSHV latent antigen LANA for degradation of the VHL and p53 tumor suppressors | Q33261811 | ||
The role of NF-kappaB in Hepatitis b virus X protein-mediated upregulation of VEGF and MMPs | Q33523861 | ||
Bicarbonate increases tumor pH and inhibits spontaneous metastases | Q33711068 | ||
MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis | Q33744153 | ||
Hepatitis B virus HBx protein deregulates cell cycle checkpoint controls | Q33765576 | ||
Kaposi's sarcoma-associated herpesvirus LANA2 is a B-cell-specific latent viral protein that inhibits p53 | Q33834993 | ||
p53 inhibition by the LANA protein of KSHV protects against cell death | Q33885642 | ||
Class II histone deacetylases are associated with VHL-independent regulation of hypoxia-inducible factor 1 alpha | Q40236336 | ||
NF-kappaB represses E-cadherin expression and enhances epithelial to mesenchymal transition of mammary epithelial cells: potential involvement of ZEB-1 and ZEB-2. | Q40252191 | ||
Role for Akt/protein kinase B and activator protein-1 in cellular proliferation induced by the human T-cell leukemia virus type 1 tax oncoprotein | Q40325197 | ||
Hepatitis C virus, ER stress, and oxidative stress | Q40432170 | ||
Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH. | Q40489574 | ||
The carboxy-terminus of the hepatitis B virus X protein is necessary and sufficient for the activation of hypoxia-inducible factor-1alpha | Q40495822 | ||
Hepatitis B viral HBx induces matrix metalloproteinase-9 gene expression through activation of ERK and PI-3K/AKT pathways: involvement of invasive potential | Q40558090 | ||
Suppression of the dual-specificity phosphatase MKP-1 enhances HIF-1 trans-activation and increases expression of EPO. | Q40606498 | ||
Hypoxia up-regulates hypoxia-inducible factor-1alpha transcription by involving phosphatidylinositol 3-kinase and nuclear factor kappaB in pulmonary artery smooth muscle cells | Q40725245 | ||
Association of latent membrane protein 1 and matrix metalloproteinase 9 with metastasis in nasopharyngeal carcinoma | Q40860124 | ||
Telomerase activation by the E6 gene product of human papillomavirus type 16. | Q41218028 | ||
Mitogen-Activated Protein Kinases and Reactive Oxygen Species: How Can ROS Activate MAPK Pathways? | Q41786663 | ||
Degradation of extracellular-matrix proteins by human cathepsin B from normal and tumour tissues | Q41849893 | ||
The physiology and pathology of the EMT. Meeting on the epithelial-mesenchymal transition. | Q41987639 | ||
Kaposi's sarcoma-associated herpesvirus latent protein LANA interacts with HIF-1 alpha to upregulate RTA expression during hypoxia: Latency control under low oxygen conditions | Q42049779 | ||
HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia | Q42512319 | ||
Hypoxia enhances vascular cell proliferation and angiogenesis in vitro via rapamycin (mTOR)-dependent signaling | Q42814573 | ||
The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival | Q42828483 | ||
G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator | Q42833351 | ||
Expression and coordinated regulation of matrix metalloproteinases in chronic hepatitis C and hepatitis C virus-induced liver cirrhosis | Q43048487 | ||
Dephosphorylated hypoxia-inducible factor 1alpha as a mediator of p53-dependent apoptosis during hypoxia | Q43761426 | ||
Hypoxia-inducible factor 1 activation by aerobic glycolysis implicates the Warburg effect in carcinogenesis | Q43954468 | ||
Overexpression of human papillomavirus (HPV) type 16 oncoproteins promotes angiogenesis via enhancing HIF-1α and VEGF expression in non-small cell lung cancer cells | Q44066614 | ||
Kaposi's sarcoma associated herpesvirus G protein-coupled receptor immortalizes human endothelial cells by activation of the VEGF receptor-2/ KDR. | Q44277985 | ||
Hepatitis B virus X protein enhances transcriptional activity of hypoxia-inducible factor-1alpha through activation of mitogen-activated protein kinase pathway | Q44509761 | ||
mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways | Q44905183 | ||
Angiogenesis soluble factors as hepatocellular carcinoma noninvasive markers for monitoring hepatitis C virus cirrhotic patients awaiting liver transplantation. | Q44934094 | ||
Hepatitis C virus core protein upregulates the expression of vascular endothelial growth factor via the nuclear factor‐κB/hypoxia‐inducible factor‐1α axis under hypoxic conditions | Q45360614 | ||
Hepatitis B virus X protein induces the expression of MTA1 and HDAC1, which enhances hypoxia signaling in hepatocellular carcinoma cells | Q45397229 | ||
Human hepatitis B virus X protein is a possible mediator of hypoxia-induced angiogenesis in hepatocarcinogenesis | Q45744352 | ||
HBx gene of hepatitis B virus induces liver cancer in transgenic mice | Q45852802 | ||
Overexpression of human papillomavirus type 16 oncoproteins enhances hypoxia-inducible factor 1 alpha protein accumulation and vascular endothelial growth factor expression in human cervical carcinoma cells | Q46198800 | ||
The potential of angiogenesis soluble markers in chronic hepatitis C. | Q46653289 | ||
The Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) K1 protein induces expression of angiogenic and invasion factors | Q47755368 | ||
HPV-16 E7 but not E6 oncogenic protein triggers both cellular immunosuppression and angiogenic processes | Q50757084 | ||
TWIST activation by hypoxia inducible factor-1 (HIF-1): implications in metastasis and development | Q51952297 | ||
p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1. | Q52173333 | ||
p38alpha MAP kinase as a sensor of reactive oxygen species in tumorigenesis | Q53336933 | ||
The purpose of the HIF-1/PHD feedback loop: To limit mTOR-induced HIF-1α | Q53427469 | ||
Expression of VEGF as prognosticator in primary nasopharyngeal cancer and its relation to EBV status | Q53658719 | ||
Epstein–Barr Virus in Burkitt's Lymphoma and Nasopharyngeal Carcinoma: EBV DNA in Biopsies of Burkitt Tumours and Anaplastic Carcinomas of the Nasopharynx | Q56689988 | ||
Oncogenes and tumor angiogenesis: the HPV-16 E6 oncoprotein activates the vascular endothelial growth factor (VEGF) gene promoter in a p53 independent manner | Q62566479 | ||
Angiogenesis Modulators Expression in Culture Cell Lines Positives for HPV-16 Oncoproteins | Q62566482 | ||
Significant differences in serum activities of matrix metalloproteinase-2 and -9 between HCV- and HBV-infected patients and carriers | Q73571853 | ||
Asian-American variants of human papillomavirus 16 and risk for cervical cancer: a case-control study | Q74459615 | ||
Expression profiles associated with aggressive behavior in Merkel cell carcinoma | Q79370590 | ||
Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice | Q79834386 | ||
MAP kinase pathways | Q81074052 | ||
Amplification of the angiogenic signal through the activation of the TSC/mTOR/HIF axis by the KSHV vGPCR in Kaposi's sarcoma | Q33895137 | ||
HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression | Q33968465 | ||
HIV, EBV and KSHV: Viral cooperation in the pathogenesis of human malignancies | Q34170639 | ||
Epstein-Barr virus and cancer | Q34297027 | ||
Acidity generated by the tumor microenvironment drives local invasion | Q34320819 | ||
Epstein-Barr virus latent membrane protein 1 induces synthesis of hypoxia-inducible factor 1 alpha | Q34346992 | ||
Hepatitis B Virus X Protein Upregulates mTOR Signaling through IKKβ to Increase Cell Proliferation and VEGF Production in Hepatocellular Carcinoma | Q34359262 | ||
Aerobic glycolysis by proliferating cells: a protective strategy against reactive oxygen species. | Q34425171 | ||
Molecular mechanisms of cellular transformation by HTLV-1 Tax. | Q34450092 | ||
Transcriptional repression of E-cadherin by human papillomavirus type 16 E6. | Q34493735 | ||
The latent nuclear antigen of Kaposi sarcoma-associated herpesvirus targets the retinoblastoma-E2F pathway and with the oncogene Hras transforms primary rat cells | Q34511161 | ||
Histone deacetylase inhibitors induce VHL and ubiquitin-independent proteasomal degradation of hypoxia-inducible factor 1alpha | Q34519869 | ||
Cancer's molecular sweet tooth and the Warburg effect. | Q34566915 | ||
Transcriptional repression of p53 promoter by hepatitis C virus core protein | Q34739314 | ||
Epstein-Barr Virus latent membrane protein 1 induces Snail and epithelial–mesenchymal transition in metastatic nasopharyngeal carcinoma | Q34745799 | ||
Human papillomavirus E7 enhances hypoxia-inducible factor 1-mediated transcription by inhibiting binding of histone deacetylases | Q34799489 | ||
Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) contains hypoxia response elements: relevance to lytic induction by hypoxia | Q35019982 | ||
Kaposi sarcoma-associated herpesvirus (KSHV): molecular biology and oncogenesis | Q35127940 | ||
Latent Kaposi's sarcoma-associated herpesvirus infection of endothelial cells activates hypoxia-induced factors | Q35139228 | ||
Depletion of Langerhans cells in human papillomavirus type 16-infected skin is associated with E6-mediated down regulation of E-cadherin | Q35155315 | ||
Increased intrahepatic cyclooxygenase 2, matrix metalloproteinase 2, and matrix metalloproteinase 9 expression is associated with progressive liver disease in chronic hepatitis C virus infection: role of viral core and NS5A proteins | Q35596979 | ||
Oncogenic Viruses and Tumor Glucose Metabolism: Like Kids in a Candy Store | Q35671327 | ||
Aberrant expression of VEGF-C is related to grade of cervical intraepithelial neoplasia (CIN) and high risk HPV, but does not predict virus clearance after treatment of CIN or prognosis of cervical cancer. | Q35769502 | ||
Kaposi's sarcoma-associated herpesvirus infection promotes invasion of primary human umbilical vein endothelial cells by inducing matrix metalloproteinases | Q35914351 | ||
Hypoxia-inducible factor-1 facilitates cervical cancer progression in human papillomavirus type 16 transgenic mice | Q35916052 | ||
Vascular endothelial growth factor/vascular permeability factor is an autocrine growth factor for AIDS-Kaposi sarcoma | Q35967211 | ||
The expression of matrix metalloproteinase 9 is enhanced by Epstein–Barr virus latent membrane protein 1 | Q36006767 | ||
Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy | Q36220497 | ||
Induction of cyclooxygenase-2 by Epstein-Barr virus latent membrane protein 1 is involved in vascular endothelial growth factor production in nasopharyngeal carcinoma cells | Q36242117 | ||
PI3K/AKT inhibition induces caspase-dependent apoptosis in HTLV-1-transformed cells | Q36358632 | ||
The Asian-American E6 Variant Protein of Human Papillomavirus 16 Alone Is Sufficient To Promote Immortalization, Transformation, and Migration of Primary Human Foreskin Keratinocytes | Q36363871 | ||
Kaposi sarcoma herpesvirus promotes endothelial-to-mesenchymal transition through Notch-dependent signaling. | Q36439695 | ||
Kaposi's sarcoma and its associated herpesvirus | Q36487309 | ||
P407 | language of work or name | English | Q1860 |
P921 | main subject | hypoxia | Q105688 |
carcinogenesis | Q1637543 | ||
P304 | page(s) | 370-383 | |
P577 | publication date | 2014-04-01 | |
P1433 | published in | Virology | Q7934867 |
P1476 | title | Hypoxia-inducible factor 1 and its role in viral carcinogenesis | |
P478 | volume | 456-457 |
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