| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1001623133 |
| P356 | DOI | 10.1038/NATURE05490 |
| P8608 | Fatcat ID | release_hefp4f5gdre2nmt3hqiaeyqrli |
| P932 | PMC publication ID | 2821831 |
| P698 | PubMed publication ID | 17220875 |
| P5875 | ResearchGate publication ID | 6580681 |
| P2093 | author name string | Brenda A Schulman | |
| Min Zhuang | |||
| James M Holton | |||
| Melanie D Ohi | |||
| Danny T Huang | |||
| Harold W Hunt | |||
| P2860 | cites work | Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1 | Q24293794 |
| Conservation in the Mechanism of Nedd8 Activation by the Human AppBp1-Uba3 Heterodimer | Q24301571 | ||
| A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8 | Q24303664 | ||
| A new NEDD8-ligating system for cullin-4A | Q24321773 | ||
| Structures of the SUMO E1 provide mechanistic insights into SUMO activation and E2 recruitment to E1 | Q24338548 | ||
| The ESCRT complexes: structure and mechanism of a membrane-trafficking network | Q24683234 | ||
| Structure of a conjugating enzyme-ubiquitin thiolester intermediate reveals a novel role for the ubiquitin tail | Q27635260 | ||
| Insights into the ubiquitin transfer cascade from the structure of the activating enzyme for NEDD8 | Q27640736 | ||
| The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1 | Q27642844 | ||
| Structure of ubiquitin refined at 1.8 A resolution | Q27728512 | ||
| Crystal structure of the human ubiquitin-like protein NEDD8 and interactions with ubiquitin pathway enzymes | Q27766356 | ||
| The ubiquitin system | Q27860803 | ||
| Biochemistry. All in the ubiquitin family | Q28143379 | ||
| Crystal structure of a fragment of mouse ubiquitin-activating enzyme | Q28240284 | ||
| Modification of proteins by ubiquitin and ubiquitin-like proteins | Q28244250 | ||
| The mechanism of ubiquitin activating enzyme. A kinetic and equilibrium analysis | Q28264747 | ||
| E2 conjugating enzymes must disengage from their E1 enzymes before E3-dependent ubiquitin and ubiquitin-like transfer | Q28270616 | ||
| Pleiotropic effects of ATP.Mg2+ binding in the catalytic cycle of ubiquitin-activating enzyme | Q28305802 | ||
| Ubiquitin-binding domains | Q29614358 | ||
| Ubiquitin: structures, functions, mechanisms | Q29616462 | ||
| Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex | Q29617624 | ||
| Retrovirus budding | Q29619900 | ||
| Identification of a multifunctional binding site on Ubc9p required for Smt3p conjugation | Q30857842 | ||
| Ubiquitin-activating enzyme. Mechanism and role in protein-ubiquitin conjugation | Q34055195 | ||
| A new ticket for entry into budding vesicles-ubiquitin | Q34365247 | ||
| Molecular determinants of polyubiquitin linkage selection by an HECT ubiquitin ligase | Q34547388 | ||
| Lingering mysteries of ubiquitin-chain assembly | Q36368593 | ||
| Structural complexity in ubiquitin recognition. | Q36431283 | ||
| Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown | Q38583853 | ||
| "Covalent affinity" purification of ubiquitin-activating enzyme | Q55062459 | ||
| Functional diversity among putative E2 isozymes in the mechanism of ubiquitin-histone ligation | Q69837130 | ||
| Functional heterogeneity of ubiquitin carrier proteins | Q70077950 | ||
| Substrate properties of site-specific mutant ubiquitin protein (G76A) reveal unexpected mechanistic features of ubiquitin-activating enzyme (E1) | Q72287606 | ||
| Characterization of the binding interface between ubiquitin and class I human ubiquitin-conjugating enzyme 2b by multidimensional heteronuclear NMR spectroscopy in solution | Q77944118 | ||
| A UbcH5/ubiquitin noncovalent complex is required for processive BRCA1-directed ubiquitination | Q82857335 | ||
| P433 | issue | 7126 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 394-8 | |
| P577 | publication date | 2007-01-25 | |
| P1433 | published in | Nature | Q180445 |
| P1476 | title | Basis for a ubiquitin-like protein thioester switch toggling E1–E2 affinity | |
| P478 | volume | 445 |
| Q27664416 | A Dual E3 Mechanism for Rub1 Ligation to Cdc53 |
| Q30386218 | A synergistic approach to protein crystallization: combination of a fixed-arm carrier with surface entropy reduction. |
| Q28542915 | A ubiquitin shuttle DC-UbP/UBTD2 reconciles protein ubiquitination and deubiquitination via linking UbE1 and USP5 enzymes |
| Q37399067 | ATG systems from the protein structural point of view |
| Q24299970 | Active site remodelling accompanies thioester bond formation in the SUMO E1 |
| Q24336527 | Adaptor protein self-assembly drives the control of a cullin-RING ubiquitin ligase |
| Q41829071 | All change: protein conformation and the ubiquitination reaction cascade |
| Q36166518 | An In Vitro Förster Resonance Energy Transfer-Based High-Throughput Screening Assay for Inhibitors of Protein–Protein Interactions in SUMOylation Pathway |
| Q96304533 | Anticancer drug discovery by targeting cullin neddylation |
| Q27675398 | Atg8 Transfer from Atg7 to Atg3: A Distinctive E1-E2 Architecture and Mechanism in the Autophagy Pathway |
| Q64946052 | Biosynthesis of the RiPP trojan horse nucleotide antibiotic microcin C is directed by the N-formyl of the peptide precursor. |
| Q29619578 | Building ubiquitin chains: E2 enzymes at work |
| Q64115469 | CUBAN, a Case Study of Selective Binding: Structural Details of the Discrimination between Ubiquitin and NEDD8 |
| Q36594657 | Characterization and Structural Insights into Selective E1-E2 Interactions in the Human and Plasmodium falciparum SUMO Conjugation Systems |
| Q102211002 | Characterization of Plasmodium falciparum NEDD8 and identification of cullins as its substrates |
| Q64166868 | Chemical Tools To Study the Proteasome |
| Q55082402 | Conformational Dynamics and Allostery in E2:E3 Interactions Drive Ubiquitination: gp78 and Ube2g2. |
| Q27865235 | Conformational transition associated with E1-E2 interaction in small ubiquitin-like modifications |
| Q27666500 | Crystal Structure of UBA2ufd-Ubc9: Insights into E1-E2 Interactions in Sumo Pathways |
| Q27660424 | Crystal Structure of the Human Ubiquitin-activating Enzyme 5 (UBA5) Bound to ATP: MECHANISTIC INSIGHTS INTO A MINIMALISTIC E1 ENZYME |
| Q27649959 | Crystal structure of human IPS-1/MAVS/VISA/Cardif caspase activation recruitment domain |
| Q27678888 | Crystal structure of the ubiquitin-like small archaeal modifier protein 2 fromHaloferax volcanii |
| Q28271246 | Crystal structures of MBP fusion proteins |
| Q40303257 | Cullin-RING E3 Ubiquitin Ligases: Bridges to Destruction. |
| Q48343629 | DENEDDYLASE1 Protein Counters Automodification of Neddylating Enzymes to Maintain NEDD8 Protein Homeostasis in Arabidopsis |
| Q37599859 | Design of an expression system to enhance MBP-mediated crystallization |
| Q34751430 | Development of FRET assay into quantitative and high-throughput screening technology platforms for protein-protein interactions |
| Q55526954 | Dissecting Distinct Roles of NEDDylation E1 Ligase Heterodimer APPBP1 and UBA3 Reveals Potential Evolution Process for Activation of Ubiquitin-related Pathways. |
| Q38749959 | Domain alternation and active site remodeling are conserved structural features of ubiquitin E1. |
| Q50296641 | Doubly neddylated UBA3:NAE1 binds AcM-UBE2F |
| Q50296640 | Doubly neddylated UBA3:NAE1 binds AcM-UBE2M |
| Q28307753 | Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging |
| Q34693707 | E1- and ubiquitin-like proteins provide a direct link between protein conjugation and sulfur transfer in archaea |
| Q35643657 | E1-E2 Interactions in Ubiquitin and Nedd8 Ligation Pathways |
| Q24316067 | E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification |
| Q27681811 | E2-binding surface on Uba3 β-grasp domain undergoes a conformational transition |
| Q28301074 | E2s: structurally economical and functionally replete |
| Q27695600 | Expression, purification, and crystal structure of N-terminal domains of human ubiquitin-activating enzyme (E1) |
| Q36946992 | Function and regulation of protein neddylation. 'Protein modifications: beyond the usual suspects' review series |
| Q28236887 | Functional diversification of the RING finger and other binuclear treble clef domains in prokaryotes and the early evolution of the ubiquitin system |
| Q33359848 | Genome-wide analysis of adaptive molecular evolution in the carnivorous plant Utricularia gibba. |
| Q90318686 | Genome-wide analysis of genes encoding core components of the ubiquitin system in soybean (Glycine max) reveals a potential role for ubiquitination in host immunity against soybean cyst nematode |
| Q33786739 | Homology Modelling of Human E1 Ubiquitin Activating Enzyme |
| Q27655732 | How the MccB bacterial ancestor of ubiquitin E1 initiates biosynthesis of the microcin C7 antibiotic |
| Q37935680 | How ubiquitination regulates the TGF-β signalling pathway: new insights and new players: new isoforms of ubiquitin-activating enzymes in the E1-E3 families join the game |
| Q34139564 | Identification and mechanistic studies of a novel ubiquitin E1 inhibitor. |
| Q41792392 | Identification of conjugation specificity determinants unmasks vestigial preference for ubiquitin within the NEDD8 E2. |
| Q90100885 | Improved Methods for Preparing the Telomere Tethering Complex Bqt1-Bqt2 for Structural Studies |
| Q39094288 | Inhibition of NEDD8 and FAT10 ligase activities through the degrading enzyme NEDD8 ultimate buster 1: A potential anticancer approach |
| Q27658921 | Insights into Ubiquitin Transfer Cascades from a Structure of a UbcH5B∼Ubiquitin-HECTNEDD4L Complex |
| Q27675408 | Insights into noncanonical E1 enzyme activation from the structure of autophagic E1 Atg7 with Atg8 |
| Q34782977 | Macromolecular juggling by ubiquitylation enzymes |
| Q34236443 | Mechanism of E1-E2 Interaction for the Inhibition of Ubl Adenylation |
| Q35939802 | Mechanistic Studies on Activation of Ubiquitin and Di-ubiquitin-like Protein, FAT10, by Ubiquitin-like Modifier Activating Enzyme 6, Uba6 |
| Q59794218 | Molecular mechanism of a covalent allosteric inhibitor of SUMO E1 activating enzyme |
| Q37566975 | Multitasking with ubiquitin through multivalent interactions |
| Q27674398 | N-Terminal Acetylation Acts as an Avidity Enhancer Within an Interconnected Multiprotein Complex |
| Q37840759 | NEDD8 Pathways in Cancer, Sine Quibus Non |
| Q50296638 | NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 |
| Q50296639 | NEDD8-UBA3:NAE1 binds a second NEDD8 |
| Q27653225 | NMR and X-RAY structures of human E2-like ubiquitin-fold modifier conjugating enzyme 1 (UFC1) reveal structural and functional conservation in the metazoan UFM1-UBA5-UFC1 ubiquination pathway |
| Q45384266 | NMR assignments of ubiquitin fold domain (UFD) in SUMO-activating enzyme subunit 2 from rice |
| Q30855071 | Natural history of the E1-like superfamily: implication for adenylation, sulfur transfer, and ubiquitin conjugation |
| Q40552928 | Neddylation E2 UBE2F Promotes the Survival of Lung Cancer Cells by Activating CRL5 to Degrade NOXA via the K11 Linkage. |
| Q93216197 | Neddylation of sterol regulatory element-binding protein 1c is a potential therapeutic target for nonalcoholic fatty liver treatment |
| Q33924565 | Orthogonal Ubiquitin Transfer through Engineered E1-E2 Cascades for Protein Ubiquitination |
| Q59032605 | Pass the protein |
| Q28306492 | Perilous journey: a tour of the ubiquitin-proteasome system |
| Q34793372 | Phage Display to Identify Nedd8‐Mimicking Peptides as Inhibitors of the Nedd8 Transfer Cascade |
| Q26996431 | Principles of allosteric interactions in cell signaling |
| Q34925373 | Profiling the cross reactivity of ubiquitin with the Nedd8 activating enzyme by phage display |
| Q37168597 | Protein interactions in the sumoylation cascade: lessons from X-ray structures |
| Q34042816 | Protein neddylation: beyond cullin-RING ligases |
| Q36677932 | RNF111-Dependent Neddylation Activates DNA Damage-Induced Ubiquitination |
| Q24298480 | RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1alpha during hypoxia |
| Q35860480 | RWD Domain as an E2 (Ubc9)-Interaction Module |
| Q36455731 | Recognition and cleavage of related to ubiquitin 1 (Rub1) and Rub1-ubiquitin chains by components of the ubiquitin-proteasome system |
| Q34185122 | Redesigning the NEDD8 Pathway with a Bacterial Genetic Screen for Ubiquitin-Like Molecule Transfer |
| Q34987659 | Regulation of T cell receptor complex-mediated signaling by ubiquitin and ubiquitin-like modifications |
| Q27865252 | Role of the Zn(2+) motif of E1 in SUMO adenylation |
| Q37067867 | Roles of ubiquitination at the synapse |
| Q51152129 | S. pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity. |
| Q42009353 | SENP8 limits aberrant neddylation of NEDD8 pathway components to promote cullin-RING ubiquitin ligase function |
| Q34918623 | SIMS: a hybrid method for rapid conformational analysis. |
| Q33289671 | Small but versatile: the extraordinary functional and structural diversity of the beta-grasp fold |
| Q38728113 | Specificity and disease in the ubiquitin system |
| Q36787669 | Split Inteins: Nature's Protein Ligases. |
| Q83477572 | Structural Insights into Functional Modes of Proteins Involved in Ubiquitin Family Pathways |
| Q42324001 | Structural analysis and evolution of specificity of the SUMO UFD E1-E2 interactions. |
| Q33987001 | Structural and functional insights to ubiquitin-like protein conjugation. |
| Q92998759 | Structural basis for adenylation and thioester bond formation in the ubiquitin E1 |
| Q27675401 | Structural basis of Atg8 activation by a homodimeric E1, Atg7 |
| Q58951347 | Structural biology: Transformative encounters |
| Q92153523 | Structural insights into E1 recognition and the ubiquitin-conjugating activity of the E2 enzyme Cdc34 |
| Q24314520 | Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation |
| Q21090578 | Structural model of the hUbA1-UbcH10 quaternary complex: in silico and experimental analysis of the protein-protein interactions between E1, E2 and ubiquitin |
| Q27644629 | Structure and Analysis of a Complex between SUMO and Ubc9 Illustrates Features of a Conserved E2-Ubl Interaction |
| Q40336938 | Structure of UBE2Z Enzyme Provides Functional Insight into Specificity in the FAT10 Protein Conjugation Machinery |
| Q24299638 | Structure of a RING E3 trapped in action reveals ligation mechanism for the ubiquitin-like protein NEDD8 |
| Q27644674 | Structure of a SUMO-binding-motif Mimic Bound to Smt3p–Ubc9p: Conservation of a Non-covalent Ubiquitin-like Protein–E2 Complex as a Platform for Selective Interactions within a SUMO Pathway |
| Q27676404 | Structure of a Ubiquitin E1-E2 Complex: Insights to E1-E2 Thioester Transfer |
| Q27690199 | Structure of the ubiquitin-activating enzyme loaded with two ubiquitin molecules |
| Q46129565 | Systematic determinations of SUMOylation activation intermediates and dynamics by a sensitive and quantitative FRET assay |
| Q24313441 | TRIP12 functions as an E3 ubiquitin ligase of APP-BP1 |
| Q36327733 | Taking it step by step: mechanistic insights from structural studies of ubiquitin/ubiquitin-like protein modification pathways |
| Q38059505 | Targeting neddylation in cancer therapy |
| Q27646842 | The Intrinsic Affinity between E2 and the Cys Domain of E1 in Ubiquitin-like Modifications |
| Q27865218 | The basis for selective E1-E2 interactions in the ISG15 conjugation system |
| Q37681979 | The enzymes in ubiquitin-like post-translational modifications |
| Q34081793 | The molecular determinants of NEDD8 specific recognition by human SENP8. |
| Q37369189 | The multiple layers of ubiquitin-dependent cell cycle control. |
| Q37971572 | The natural history of ubiquitin and ubiquitin-related domains |
| Q36721779 | The role of allostery in the ubiquitin-proteasome system |
| Q50296642 | Transfer of NEDD8 to AcM-UBE2F |
| Q50296643 | Transfer of NEDD8 to AcM-UBE2M |
| Q41174619 | Tumor Necrosis Factor α-induced Inflammation Is Increased but Apoptosis Is Inhibited by Common Food Additive Carrageenan |
| Q34225698 | Twists and turns in ubiquitin‐like protein conjugation cascades |
| Q93241593 | UFM1-Activating Enzyme 5 (Uba5) Requires an Extension to Get the Job Done Right |
| Q85554027 | Ubiquitin- and ubiquitin-like proteins-conjugating enzymes (E2s) in breast cancer |
| Q24323309 | Ubiquitin-conjugating enzyme UBE2D2 is responsible for FBXW2 (F-box and WD repeat domain containing 2)-mediated human GCM1 (glial cell missing homolog 1) ubiquitination and degradation |
| Q39149390 | Ubiquitin-like Protein Conjugation: Structures, Chemistry, and Mechanism |
| Q24647626 | Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways |
| Q36283663 | Using protein motion to read, write, and erase ubiquitin signals |
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