scholarly article | Q13442814 |
P50 | author | Kate E Coleman | Q88004189 |
Tony T Huang | Q88004193 | ||
Beatrix Ueberheide | Q56435647 | ||
Mathew J K Jones | Q82034734 | ||
P2093 | author name string | Miklós Békés | |
Jessica R Chapman | |||
Sarah B Crist | |||
P2860 | cites work | Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1 | Q24293794 |
A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1 | Q24301361 | ||
ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain | Q24303631 | ||
Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis. | Q24304921 | ||
Regulation of nucleolar signalling to p53 through NEDDylation of L11 | Q24310534 | ||
Identification of c-MYC as a target of the APC pathway | Q24310637 | ||
PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex | Q24312855 | ||
Ribosomal proteins are targets for the NEDD8 pathway | Q24313502 | ||
Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation | Q24314520 | ||
Dephosphorylation and activation of a p34cdc2/cyclin B complex in vitro by human CDC25 protein | Q24314987 | ||
E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification | Q24316067 | ||
SCCRO (DCUN1D1) is an essential component of the E3 complex for neddylation | Q24317319 | ||
Structural basis of NEDD8 ubiquitin discrimination by the deNEDDylating enzyme NEDP1. | Q24529121 | ||
RNA-guided human genome engineering via Cas9 | Q24598394 | ||
Systematic and quantitative assessment of the ubiquitin-modified proteome | Q24634631 | ||
Loss of the mammalian APC/C activator FZR1 shortens G1 and lengthens S phase but has little effect on exit from mitosis | Q39782770 | ||
Changes in the ratio of free NEDD8 to ubiquitin triggers NEDDylation by ubiquitin enzymes | Q41141041 | ||
Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system | Q41483751 | ||
Identification of conjugation specificity determinants unmasks vestigial preference for ubiquitin within the NEDD8 E2. | Q41792392 | ||
Dynamic regulation of the PR-Set7 histone methyltransferase is required for normal cell cycle progression | Q42376622 | ||
Depletion of Uhrf1 inhibits chromosomal DNA replication in Xenopus egg extracts | Q42585685 | ||
Human ARF binds E2F1 and inhibits its transcriptional activity. | Q43583428 | ||
The covalent modifier Nedd8 is critical for the activation of Smurf1 ubiquitin ligase in tumorigenesis | Q45345755 | ||
DEN1 deneddylates non-cullin proteins in vivo. | Q45345762 | ||
Nuclear localization signal sequence is required for VACM-1/CUL5-dependent regulation of cellular growth | Q47597881 | ||
DENEDDYLASE1 deconjugates NEDD8 from non-cullin protein substrates in Arabidopsis thaliana | Q58001200 | ||
Deletion of the Cul1 gene in mice causes arrest in early embryogenesis and accumulation of cyclin E | Q58236966 | ||
Wnt/β-catenin signaling and disease | Q26823272 | ||
Basis for a ubiquitin-like protein thioester switch toggling E1–E2 affinity | Q27641129 | ||
Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases | Q27644446 | ||
Dcn1 functions as a scaffold-type E3 ligase for cullin neddylation | Q27649565 | ||
Substrate-assisted inhibition of ubiquitin-like protein-activating enzymes: the NEDD8 E1 inhibitor MLN4924 forms a NEDD8-AMP mimetic in situ | Q27659474 | ||
N-Terminal Acetylation Acts as an Avidity Enhancer Within an Interconnected Multiprotein Complex | Q27674398 | ||
Structural Conservation of Distinctive N-terminal Acetylation-Dependent Interactions across a Family of Mammalian NEDD8 Ligation Enzymes | Q27675332 | ||
Crystal structure of the human COP9 signalosome | Q27694578 | ||
Cullin-RING ubiquitin E3 ligase regulation by the COP9 signalosome | Q27704406 | ||
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources | Q27860739 | ||
The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin. | Q27863647 | ||
Small ubiquitin-related modifier (SUMO)-specific proteases: profiling the specificities and activities of human SENPs | Q27865192 | ||
Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1. | Q27931858 | ||
Ubiquitylation, neddylation and the DNA damage response | Q28087342 | ||
Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists | Q28131785 | ||
Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage | Q28182301 | ||
The SCF(Skp2) ubiquitin ligase complex interacts with the human replication licensing factor Cdt1 and regulates Cdt1 degradation | Q28184480 | ||
Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome | Q28187304 | ||
Expression of VACM-1 protein in cultured rat adrenal endothelial cells is linked to the cell cycle | Q28202165 | ||
Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase | Q28202311 | ||
NEDP1, a highly conserved cysteine protease that deNEDDylates Cullins | Q28202321 | ||
Identification and characterization of DEN1, a deneddylase of the ULP family | Q28205400 | ||
DEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1 | Q28205415 | ||
Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase | Q28215069 | ||
SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase | Q28234989 | ||
Deregulated expression of E2F-1 induces cyclin A- and E-associated kinase activities independently from cell cycle position | Q28240239 | ||
The retinoblastoma gene and its product are targeted by ICBP90: a key mechanism in the G1/S transition during the cell cycle | Q28260808 | ||
Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity | Q28270986 | ||
A practical recipe for stable isotope labeling by amino acids in cell culture (SILAC) | Q28296386 | ||
A rate limiting function of cdc25A for S phase entry inversely correlates with tyrosine dephosphorylation of Cdk2 | Q28297403 | ||
Dual mode of degradation of Cdc25 A phosphatase | Q28386155 | ||
Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E | Q28504517 | ||
Expression of VACM-1/cul5 mutant in endothelial cells induces MAPK phosphorylation and maspin degradation and converts cells to the angiogenic phenotype | Q28578323 | ||
Ectopic expression of Cdc25A accelerates the G(1)/S transition and leads to premature activation of cyclin E- and cyclin A-dependent kinases | Q28610271 | ||
MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification | Q29547200 | ||
An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer | Q29616732 | ||
CRL4(Cdt2) regulates cell proliferation and histone gene expression by targeting PR-Set7/Set8 for degradation | Q30430339 | ||
Cleavage of the C-terminus of NEDD8 by UCH-L3. | Q31990233 | ||
Phosphorylation of VACM-1/Cul5 by protein kinase A regulates its neddylation and antiproliferative effect | Q33717656 | ||
The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2. | Q33889383 | ||
Downregulation of miR-7 upregulates Cullin 5 (CUL5) to facilitate G1/S transition in human hepatocellular carcinoma cells | Q34039349 | ||
Protein neddylation: beyond cullin-RING ligases | Q34042816 | ||
Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profiling | Q34159143 | ||
The NEDD8 Conjugation Pathway and Its Relevance in Cancer Biology and Therapy | Q34202686 | ||
CRL4Cdt2-Mediated Destruction of the Histone Methyltransferase Set8 Prevents Premature Chromatin Compaction in S Phase | Q34215301 | ||
The dynamics and mechanism of SUMO chain deconjugation by SUMO-specific proteases | Q34695640 | ||
Identification of SCF ubiquitin ligase substrates by global protein stability profiling | Q34874145 | ||
Down-regulation of UHRF1, associated with re-expression of tumor suppressor genes, is a common feature of natural compounds exhibiting anti-cancer properties | Q34989248 | ||
FOXP1 potentiates Wnt/β-catenin signaling in diffuse large B cell lymphoma. | Q35167200 | ||
Suppression of glioblastoma by targeting the overactivated protein neddylation pathway | Q36082492 | ||
Large-scale identification of ubiquitination sites by mass spectrometry | Q36496727 | ||
Deubiquitinases as a signaling target of oxidative stress | Q36501472 | ||
RNF111-dependent neddylation activates DNA damage-induced ubiquitination | Q36677932 | ||
Cand1 promotes assembly of new SCF complexes through dynamic exchange of F box proteins | Q36850952 | ||
Multimodal activation of the ubiquitin ligase SCF by Nedd8 conjugation | Q37101488 | ||
A targeted proteomic analysis of the ubiquitin-like modifier nedd8 and associated proteins. | Q37178794 | ||
Targeted inhibition of the COP9 signalosome for treatment of cancer | Q37364323 | ||
Uncovering the role of APC-Cdh1 in generating the dynamics of S-phase onset | Q37582528 | ||
UHRF1 overexpression drives DNA hypomethylation and hepatocellular carcinoma | Q37632823 | ||
Overactivated neddylation pathway as a therapeutic target in lung cancer. | Q38992669 | ||
DUB-resistant ubiquitin to survey ubiquitination switches in mammalian cells | Q39065396 | ||
Mps1 kinase activity restrains anaphase during an unperturbed mitosis and targets Mad2 to kinetochores. | Q39131699 | ||
DNA damage regulates UHRF1 stability via the SCF(β-TrCP) E3 ligase | Q39214600 | ||
NEDDylation controls the target specificity of E2F1 and apoptosis induction. | Q39273538 | ||
NEDDylation regulates E2F-1-dependent transcription | Q39307613 | ||
Global identification of modular cullin-RING ligase substrates | Q39462405 | ||
Increased Cul1 expression promotes melanoma cell proliferation through regulating p27 expression | Q39650489 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P407 | language of work or name | English | Q1860 |
P921 | main subject | protein neddylation | Q21115705 |
P577 | publication date | 2017-05-05 | |
P1433 | published in | eLife | Q2000008 |
P1476 | title | SENP8 limits aberrant neddylation of NEDD8 pathway components to promote cullin-RING ubiquitin ligase function | |
P478 | volume | 6 |
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